Follow
Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
-
FEB 22, 2016Immunology
Around 15 to 20 percent of children with acute lymphoblastic leukemia (ALL) have cancerous cells derived from T lymphocy ...Written By: Kara MarkerFEB 21, 2016Chemistry & Physics
In 1952, a famous experiment mixed together chemicals that were present early in Earth’s history, then approximate ...Written By: Futurity (futurity.org)FEB 19, 2016Clinical & Molecular DX
Tissue bioengineering is rapidly expanding as the demand for lab-grown tissues grows steadily due to shortages in donate ...FEB 17, 2016Health & Medicine
Researchers have found how a cancer-causing retrovirus RSV brings together an unexpected number of retroviral integrase ...Written By: Julianne ChiaetFEB 12, 2016Health & Medicine
Researchers have transformed mouse fibroblasts, the most common type of cell in mammalian connective tissue, into induce ...Written By: Julianne ChiaetFEB 12, 2016Immunology
Vitamin D is an essential micronutrient that must be obtained from the environment; the body does not make it on its own ...Written By: Kara MarkerFEB 10, 2016Health & Medicine
Researchers have found a chain of reactions within nerve cells that signal pain related to inflammation. Developing drug ...Written By: Julianne ChiaetFEB 10, 2016Genetics & Genomics
Scientists from the University of North Carolina at Charlotte, North Carolina Central University’s Nutrition Resea ...Written By: Kara MarkerFEB 09, 2016Health & Medicine
Obesity, diabetes, and other metabolic conditions are a huge problem for which there is not yet an effective solution. A ...Written By: Cassidy ReichFEB 05, 2016Cancer
Overall brain cancer is rare, but it’s actually the most common form of solid tumors in children under 15 years ol ...Written By: Kara MarkerFEB 04, 2016Health & Medicine
Besides having on average larger feet than short people, a new study shows tall people are also more at risk for getting ...Written By: Kara MarkerFEB 04, 2016Immunology
The body needs regulatory T cells (Tregs) on the sidelines of an immune attack, making sure tempers don’t run too ...Written By: Kara MarkerFEB 02, 2016Cell & Molecular Biology
A team led by scientists at The Scripps Research Institute (TSRI) has solved a long-standing mystery in cell biology by ...Written By: The Scripps Research Institute (TSRI)FEB 02, 2016Clinical & Molecular DX
In a historic, unprecedented move, UK national fertility regulators have given the green light for scientists to use the ...JAN 30, 2016Cell & Molecular Biology
To decide whether and where to move in the body, cells need to read chemical signals in their environment—and they ...Written By: Futurity (futurity.org)JAN 29, 2016Health & Medicine
A drug used to treat high blood pressure could be the answer to treating and preventing Alzheimer’s disease. Alzhe ...Written By: Julianne ChiaetJAN 29, 2016Immunology
Scientists are constantly trying to pinpoint the causation behind children who develop autism, often looking to genetics ...Written By: Kara MarkerJAN 28, 2016Neuroscience
Recent years have seen an incredible rise in the research and discussion of neuroinflammation, especially in regards to ...Written By: Cassidy ReichJAN 27, 2016Clinical & Molecular DX
Females are not the weaker sex when it comes to battling the flu virus, says a new study. Published in the American Jour ...JAN 27, 2016Neuroscience
Babies born in the United States are routinely screened for lead levels and have been for decades. It’s well docum ...Written By: Brenda Kelley KimJAN 26, 2016Clinical & Molecular DX
A group at the Icahn School of Medicine at Mount Sinai in New York City recently published a very interesting and exciti ...Written By: Cassidy ReichJAN 25, 2016Chemistry & Physics
Chemists at The Scripps Research Institute (TSRI) have devised a new and widely applicable technique for building potent ...Written By: The Scripps Research Institute (TSRI)JAN 20, 2016Cell & Molecular Biology
Many cells have microscopic gates, called ion channels, which open to allow the flow of ions across the cell membrane. T ...Written By: The Scripps Research Institute (TSRI)JAN 19, 2016Immunology
A new study led by scientists at The Scripps Research Institute (TSRI) shows how dangerous autoimmune responses, seen in ...Written By: The Scripps Research Institute (TSRI)
FEB 22, 2016
Immunology
Around 15 to 20 percent of children with acute lymphoblastic leukemia (ALL) have cancerous cells derived from T lymphocy
...
Written By:
Kara Marker
FEB 21, 2016
Chemistry & Physics
In 1952, a famous experiment mixed together chemicals that were present early in Earth’s history, then approximate
...
Written By:
Futurity (futurity.org)
FEB 19, 2016
Clinical & Molecular DX
Tissue bioengineering is rapidly expanding as the demand for lab-grown tissues grows steadily due to shortages in donate
...
FEB 17, 2016
Health & Medicine
Researchers have found how a cancer-causing retrovirus RSV brings together an unexpected number of retroviral integrase
...
Written By:
Julianne Chiaet
FEB 12, 2016
Health & Medicine
Researchers have transformed mouse fibroblasts, the most common type of cell in mammalian connective tissue, into induce
...
Written By:
Julianne Chiaet
FEB 12, 2016
Immunology
Vitamin D is an essential micronutrient that must be obtained from the environment; the body does not make it on its own
...
Written By:
Kara Marker
FEB 10, 2016
Health & Medicine
Researchers have found a chain of reactions within nerve cells that signal pain related to inflammation. Developing drug
...
Written By:
Julianne Chiaet
FEB 10, 2016
Genetics & Genomics
Scientists from the University of North Carolina at Charlotte, North Carolina Central University’s Nutrition Resea
...
Written By:
Kara Marker
FEB 09, 2016
Health & Medicine
Obesity, diabetes, and other metabolic conditions are a huge problem for which there is not yet an effective solution. A
...
Written By:
Cassidy Reich
FEB 05, 2016
Cancer
Overall brain cancer is rare, but it’s actually the most common form of solid tumors in children under 15 years ol
...
Written By:
Kara Marker
FEB 04, 2016
Health & Medicine
Besides having on average larger feet than short people, a new study shows tall people are also more at risk for getting
...
Written By:
Kara Marker
FEB 04, 2016
Immunology
The body needs regulatory T cells (Tregs) on the sidelines of an immune attack, making sure tempers don’t run too
...
Written By:
Kara Marker
FEB 02, 2016
Cell & Molecular Biology
A team led by scientists at The Scripps Research Institute (TSRI) has solved a long-standing mystery in cell biology by
...
Written By:
The Scripps Research Institute (TSRI)
FEB 02, 2016
Clinical & Molecular DX
In a historic, unprecedented move, UK national fertility regulators have given the green light for scientists to use the
...
JAN 30, 2016
Cell & Molecular Biology
To decide whether and where to move in the body, cells need to read chemical signals in their environment—and they
...
Written By:
Futurity (futurity.org)
JAN 29, 2016
Health & Medicine
A drug used to treat high blood pressure could be the answer to treating and preventing Alzheimer’s disease. Alzhe
...
Written By:
Julianne Chiaet
JAN 29, 2016
Immunology
Scientists are constantly trying to pinpoint the causation behind children who develop autism, often looking to genetics
...
Written By:
Kara Marker
JAN 28, 2016
Neuroscience
Recent years have seen an incredible rise in the research and discussion of neuroinflammation, especially in regards to
...
Written By:
Cassidy Reich
JAN 27, 2016
Clinical & Molecular DX
Females are not the weaker sex when it comes to battling the flu virus, says a new study. Published in the American Jour
...
JAN 27, 2016
Neuroscience
Babies born in the United States are routinely screened for lead levels and have been for decades. It’s well docum
...
Written By:
Brenda Kelley Kim
JAN 26, 2016
Clinical & Molecular DX
A group at the Icahn School of Medicine at Mount Sinai in New York City recently published a very interesting and exciti
...
Written By:
Cassidy Reich
JAN 25, 2016
Chemistry & Physics
Chemists at The Scripps Research Institute (TSRI) have devised a new and widely applicable technique for building potent
...
Written By:
The Scripps Research Institute (TSRI)
JAN 20, 2016
Cell & Molecular Biology
Many cells have microscopic gates, called ion channels, which open to allow the flow of ions across the cell membrane. T
...
Written By:
The Scripps Research Institute (TSRI)
JAN 19, 2016
Immunology
A new study led by scientists at The Scripps Research Institute (TSRI) shows how dangerous autoimmune responses, seen in
...
Written By:
The Scripps Research Institute (TSRI)