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    Chromatin

    Chromatin: is a complex of DNA and proteins that forms chromosomes within the nucleus of eukaryotic cells. Chromatin exists in two forms. One form, called euchromatin, is less condensed and can be transcribed. The second form, called heterochromatin, is highly condensed and is typically not transcribed.

    Webinars

    • SEP 03, 2020 | 11:00 AM
      Filtered Fume Hoods: Expert insight on improving your lab's green initiative
      Filtered Fume Hoods: Expert insight on improving your lab's green...
      DATE: September 3, 2020 TIME: 9:00 am PDT, 12:00 pm EDT So many considerations go into a lab. How many fume hoods do I need? What chemicals can they handle and how often? What about ducting?...
      Speaker: Kasey Fulmer , Kenneth Crooks
      Sponsored By: Labconco
      11
      SEP 03, 2020 | 9:00 AM
      The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
      The Complexities of SV Analytical Ultracentrifugation: AAVs are...
      DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
      Speaker: Dr. Lake Paul
      Sponsored By: Beckman Coulter Life Sciences
      12
      JUL 29, 2020 | 12:00 PM
      Linking Cancer Metabolism to Neurodegeneration
      Linking Cancer Metabolism to Neurodegeneration
      The major function of mitochondria in cellular homeostasis has been the generation of ATP through oxidative phosphorylation. However, we have previously demonstrated that mitochondria can se...
      Speaker: Navdeep S. Chandel PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      3
      JUN 16, 2020 | 8:00 AM
      Measuring molecular interactions by multi-wavelength analytical ultracentrifugation
      Measuring molecular interactions by multi-wavelength analytical...
      DATE: June 16, 2020 TIME: 8:00am PT Multi-wavelength analysis of hydrodynamic data collected on the latest analytical ultracentrifugation instruments provides additional resolution and insig...
      Speaker: Borries Demeler, PhD
      Sponsored By: Beckman Coulter Life Sciences
      22 1
      JUN 02, 2020 | 4:30 PM
      Plenary Address
      Plenary Address
      ...
      Speaker: Plenary Keynote: Xiaowei Zhuang, PhD
      Presented at: 2020 6th annual BRAIN Initiative Investigators Virtual Meeting
      1
      APR 29, 2020 | 6:00 AM
      High-Throughput assessment of ChIP-grade capability with Luminex xMAP technology
      High-Throughput assessment of ChIP-grade capability with Luminex...
      Histone post-translational modifications (PTMs) play pivotal roles in chromatin dynamics and function, with alterations in the healthy profile associated with diverse human pathologies. The...
      Speaker: Michael-Christopher Keogh, PhD
      Presented at: xMAP® Connect Virtual Conference (On-Demand)
      1
      APR 24, 2020 | 8:00 AM
      Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide Structural Variant Analysis
      Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide...
      DATE: April 24, 2020 TIME: 8:00am PT, 11:00am ET, 5:00pm CET...
      Speaker: Ben Clifford, PhD , Sven Bocklandt, PhD
      Sponsored By: Bionano
      11
      APR 21, 2020 | 12:00 PM
      Expanding the Hi-C toolbox: New high-resolution approaches for diploid genome phasing, protein-directed chromatin architecture mapping and more
      Expanding the Hi-C toolbox: New high-resolution approaches for...
      Careful and deliberate packaging of the genome is essential to ensuring correct and timely transcriptional programs. Chromatin conformation capture (3C and Hi-C) is a powerful approach for c...
      Speaker: Iain Russell, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      Sponsored By: Dovetail Genomics
      1
      APR 21, 2020 | 12:00 AM
      Contribution of transposons to structural variation and phenotypic diversity in tomato
      Contribution of transposons to structural variation and phenotypic...
      Structural variation within plant genomes has fueled domestication and selection of traits critical for modern breeding of crop plants. Nevertheless, dissecting the diversity of structural v...
      Speaker: Matthias Benoit, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 15, 2020 | 9:00 AM
      Single-cell multi-omics: DNA methylation and 3D genome
      Single-cell multi-omics: DNA methylation and 3D genome
      DATE: April 15, 2020 TIME: 9:00am PT, 12:00pm ET We report a molecular assay, Methyl-HiC, that can simultaneously capture the chromosome conformation and DNA methylome in a cell. Methyl-HiC...
      Speaker: Yaping Liu, Ph.D.
      Sponsored By: Zymo Research
      9 3
      APR 02, 2020 | 8:00 AM
      Bionano Genome Imaging unravels complex structural rearrangements induced by replication stress in liver cancer
      Bionano Genome Imaging unravels complex structural rearrangements...
      DATE: April 2, 2020 TIME: 8:00am PT, 11:00am ET Cyclins A2 and E1 regulate the cell cycle by promoting S phase entry and progression. We recently identified a hepatocellular carcinoma (HCC)...
      Speaker: Eric Letouzé, PhD
      Sponsored By: Bionano
      14
      OCT 30, 2019 | 7:00 AM
      A Novel Approach for Single-cell Multi-omic Analysis to Identify Regulatory Signatures in Cancer
      A Novel Approach for Single-cell Multi-omic Analysis to Identify...
      DATE: October 30, 2019TIME: 7:00am PDTJoin us for a webinar to learn how to apply single cell methods to study cancer. Dr. William Greenleaf, Associate Professor from Stanford Universit...
      Speaker: William J. Greenleaf, Ph.D
      Sponsored By: 10x Genomics
      18 1
      SEP 05, 2019 | 7:00 AM
      The bread and butter method of genomics: How to improve your (q)PCR
      The bread and butter method of genomics: How to improve your (q)PCR
      DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
      Speaker: Tim Schommartz, PhD
      Sponsored By: Eppendorf
      17 1
      MAY 08, 2019 | 6:00 AM
      Upgrading the CRISPR Toolbox - New Strategies Sharpen the CRISPR-Cas9 Scissors Utilizing Visualization and Chromatic Accessibility
      Upgrading the CRISPR Toolbox - New Strategies Sharpen the CRISPR-Cas9...
      In this webinar, we will discuss our most recent additions to our CRISPR protein portfolio, the GFP-SpCas9 and GFP-eCas9 fusion proteins. The two GFP-Cas9 fusion proteins offer great visualiz...
      Speaker: Michelle Ding, M.S. , Yanfang Jiang, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      Sponsored By: MilliporeSigma
      1
      MAY 08, 2019 | 6:00 AM
      C.E. CREDITS
      Novel DNA Methylation in Mammals
      Novel DNA Methylation in Mammals
      Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA. Although the critical role of DNA 5-methylcytosine (5mC) in the regulation of transcription is recognize...
      Speaker: Tao Wu, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      2
      OCT 31, 2018 | 8:00 AM
      Chromatin immunoprecipitation: Five steps to great results
      Chromatin immunoprecipitation: Five steps to great results
      DATE: October 31, 2018TIME: 8:00AM PDTChromatin immunoprecipitation (ChIP) is a technique researchers employ to obtain a snapshot of protein-DNA interactions in the cell.  ChI...
      Speaker: Eliza Small, PhD
      Sponsored By: Thermo Fisher Scientific
      10
      OCT 23, 2018 | 9:00 AM
      Chicago® and Dovetail™ Hi-C yield chromosome length scaffolds of the Ixodes scapularis genome
      Chicago® and Dovetail™ Hi-C yield chromosome length scaffolds...
      DATE: October 23, 2018TIME: 9:00AM PDTIxodes scapularis is the principal vector of the Lyme disease spirochete, Borrelia burgdorferi. I. scapularis genome was the first and only...
      Speaker: Monika Gulia-Nuss
      Sponsored By: Dovetail Genomics
      5
      JUN 21, 2018 | 1:30 PM
      Pharmacogenetics in Psychiatry
      Pharmacogenetics in Psychiatry
      There is robust evidence supporting strong association with CYP450 (Phase 1) enzymes and influence on drug levels (affecting response & side effects in many cases) with many psychotropic...
      Speaker: Daniel Mueller, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      1
      JUN 21, 2018 | 12:00 PM
      Whole Genome Sequencing As A Valuable Clinical Tool For the Management of Cancer Patients
      Whole Genome Sequencing As A Valuable Clinical Tool For the Management...
      Advances in DNA sequencing, based upon massively parallel sequencing, has resulted in dramatic advances in DNA sequence output in the past few years. It is now possible to generate terrabases...
      Speaker: David Smith, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      1
      JUN 21, 2018 | 10:30 AM
      Setting Up Next-Generation Sequencing for the Needs of Routine Molecular Diagnostics With a Focus on the Suitability of the GeneReader NGS System for Lung Cancer Patients
      Setting Up Next-Generation Sequencing for the Needs of Routine...
      The introduction of targeted therapies into the clinical management of lung adenocarcinoma has had a massive impact on patient care. Multiple driver mutations are now druggable and treatments...
      Speaker: Paul Hofman, MD, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      JUN 21, 2018 | 9:00 AM
      Can AI Beat Cancer?
      Can AI Beat Cancer?
      Finding effective treatments for cancer is fundamentally  a high-dimensional probabilistic planning, search, and optimization problem, characterized by  thousands of molecular subty...
      Speaker: Marty Tenenbaum, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      1
      JUN 21, 2018 | 7:30 AM
      Keynote Presentation: Paving the Path Towards Precision Medicine in Inflammatory Bowel Diseases
      Keynote Presentation: Paving the Path Towards Precision Medicine...
      Crohn’s disease and ulcerative colitis also known as inflammatory bowel diseases or IBD, are characterized by chronic, recurrent inflammation of the gastrointestinal tract, which result...
      Speaker: Andres Hurtado-Lorenzo, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      1
      JUN 21, 2018 | 6:00 AM
      Rapid Whole Genome Sequencing in the NICU and PICU Decreases Infant Morbidity and Mortality
      Rapid Whole Genome Sequencing in the NICU and PICU Decreases Infant...
      Rare disease affects 30 million people in the United States, with nearly 50% of cases affecting children. Because nearly 80% of rare diseases are genetic, advancements in genomic testing are...
      Speaker: Stephen Kingsmore, PhD, MD
      Presented at: Precision Medicine Virtual Event Series 2018
      1
      JUN 20, 2018 | 1:30 PM
      Regulation of Precision Medicine
      Regulation of Precision Medicine
      Regulation of precision medicine is rapidly evolving.  The pre-existing regulatory framework did not contemplate many of the products and technologies which are becoming available with p...
      Speaker: Neil Belson
      Presented at: Precision Medicine Virtual Event Series 2018
      3
    SEP 03, 2020 | 11:00 AM
    Filtered Fume Hoods: Expert insight on improving your lab's green initiative
    Filtered Fume Hoods: Expert insight on improving your lab's green...
    DATE: September 3, 2020 TIME: 9:00 am PDT, 12:00 pm EDT So many considerations go into a lab. How many fume hoods do I need? What chemicals can they handle and how often? What about ducting?...
    Speaker: Kasey Fulmer , Kenneth Crooks
    Sponsored By: Labconco
    11
    SEP 03, 2020 | 9:00 AM
    The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
    The Complexities of SV Analytical Ultracentrifugation: AAVs are...
    DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
    Speaker: Dr. Lake Paul
    Sponsored By: Beckman Coulter Life Sciences
    12
    JUL 29, 2020 | 12:00 PM
    Linking Cancer Metabolism to Neurodegeneration
    Linking Cancer Metabolism to Neurodegeneration
    The major function of mitochondria in cellular homeostasis has been the generation of ATP through oxidative phosphorylation. However, we have previously demonstrated that mitochondria can se...
    Speaker: Navdeep S. Chandel PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    3
    JUN 16, 2020 | 8:00 AM
    Measuring molecular interactions by multi-wavelength analytical ultracentrifugation
    Measuring molecular interactions by multi-wavelength analytical...
    DATE: June 16, 2020 TIME: 8:00am PT Multi-wavelength analysis of hydrodynamic data collected on the latest analytical ultracentrifugation instruments provides additional resolution and insig...
    Speaker: Borries Demeler, PhD
    Sponsored By: Beckman Coulter Life Sciences
    22 1
    JUN 02, 2020 | 4:30 PM
    Plenary Address
    Plenary Address
    ...
    Speaker: Plenary Keynote: Xiaowei Zhuang, PhD
    Presented at: 2020 6th annual BRAIN Initiative Investigators Virtual Meeting
    1
     
     
  • APR 29, 2020 | 6:00 AM
    High-Throughput assessment of ChIP-grade capability with Luminex xMAP technology
    High-Throughput assessment of ChIP-grade capability with Luminex...
    Histone post-translational modifications (PTMs) play pivotal roles in chromatin dynamics and function, with alterations in the healthy profile associated with diverse human pathologies. The...
    Speaker: Michael-Christopher Keogh, PhD
    Presented at: xMAP® Connect Virtual Conference (On-Demand)
    1
    APR 24, 2020 | 8:00 AM
    Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide Structural Variant Analysis
    Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide...
    DATE: April 24, 2020 TIME: 8:00am PT, 11:00am ET, 5:00pm CET...
    Speaker: Ben Clifford, PhD , Sven Bocklandt, PhD
    Sponsored By: Bionano
    11
    APR 21, 2020 | 12:00 PM
    Expanding the Hi-C toolbox: New high-resolution approaches for diploid genome phasing, protein-directed chromatin architecture mapping and more
    Expanding the Hi-C toolbox: New high-resolution approaches for...
    Careful and deliberate packaging of the genome is essential to ensuring correct and timely transcriptional programs. Chromatin conformation capture (3C and Hi-C) is a powerful approach for c...
    Speaker: Iain Russell, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    Sponsored By: Dovetail Genomics
    1
    APR 21, 2020 | 12:00 AM
    Contribution of transposons to structural variation and phenotypic diversity in tomato
    Contribution of transposons to structural variation and phenotypic...
    Structural variation within plant genomes has fueled domestication and selection of traits critical for modern breeding of crop plants. Nevertheless, dissecting the diversity of structural v...
    Speaker: Matthias Benoit, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 15, 2020 | 9:00 AM
    Single-cell multi-omics: DNA methylation and 3D genome
    Single-cell multi-omics: DNA methylation and 3D genome
    DATE: April 15, 2020 TIME: 9:00am PT, 12:00pm ET We report a molecular assay, Methyl-HiC, that can simultaneously capture the chromosome conformation and DNA methylome in a cell. Methyl-HiC...
    Speaker: Yaping Liu, Ph.D.
    Sponsored By: Zymo Research
    9 3
     
     
  • APR 02, 2020 | 8:00 AM
    Bionano Genome Imaging unravels complex structural rearrangements induced by replication stress in liver cancer
    Bionano Genome Imaging unravels complex structural rearrangements...
    DATE: April 2, 2020 TIME: 8:00am PT, 11:00am ET Cyclins A2 and E1 regulate the cell cycle by promoting S phase entry and progression. We recently identified a hepatocellular carcinoma (HCC)...
    Speaker: Eric Letouzé, PhD
    Sponsored By: Bionano
    14
    OCT 30, 2019 | 7:00 AM
    A Novel Approach for Single-cell Multi-omic Analysis to Identify Regulatory Signatures in Cancer
    A Novel Approach for Single-cell Multi-omic Analysis to Identify...
    DATE: October 30, 2019TIME: 7:00am PDTJoin us for a webinar to learn how to apply single cell methods to study cancer. Dr. William Greenleaf, Associate Professor from Stanford Universit...
    Speaker: William J. Greenleaf, Ph.D
    Sponsored By: 10x Genomics
    18 1
    SEP 05, 2019 | 7:00 AM
    The bread and butter method of genomics: How to improve your (q)PCR
    The bread and butter method of genomics: How to improve your (q)PCR
    DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
    Speaker: Tim Schommartz, PhD
    Sponsored By: Eppendorf
    17 1
    MAY 08, 2019 | 6:00 AM
    Upgrading the CRISPR Toolbox - New Strategies Sharpen the CRISPR-Cas9 Scissors Utilizing Visualization and Chromatic Accessibility
    Upgrading the CRISPR Toolbox - New Strategies Sharpen the CRISPR-Cas9...
    In this webinar, we will discuss our most recent additions to our CRISPR protein portfolio, the GFP-SpCas9 and GFP-eCas9 fusion proteins. The two GFP-Cas9 fusion proteins offer great visualiz...
    Speaker: Michelle Ding, M.S. , Yanfang Jiang, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    Sponsored By: MilliporeSigma
    1
    MAY 08, 2019 | 6:00 AM
    C.E. CREDITS
    Novel DNA Methylation in Mammals
    Novel DNA Methylation in Mammals
    Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA. Although the critical role of DNA 5-methylcytosine (5mC) in the regulation of transcription is recognize...
    Speaker: Tao Wu, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    2
     
     
  • OCT 31, 2018 | 8:00 AM
    Chromatin immunoprecipitation: Five steps to great results
    Chromatin immunoprecipitation: Five steps to great results
    DATE: October 31, 2018TIME: 8:00AM PDTChromatin immunoprecipitation (ChIP) is a technique researchers employ to obtain a snapshot of protein-DNA interactions in the cell.  ChI...
    Speaker: Eliza Small, PhD
    Sponsored By: Thermo Fisher Scientific
    10
    OCT 23, 2018 | 9:00 AM
    Chicago® and Dovetail™ Hi-C yield chromosome length scaffolds of the Ixodes scapularis genome
    Chicago® and Dovetail™ Hi-C yield chromosome length scaffolds...
    DATE: October 23, 2018TIME: 9:00AM PDTIxodes scapularis is the principal vector of the Lyme disease spirochete, Borrelia burgdorferi. I. scapularis genome was the first and only...
    Speaker: Monika Gulia-Nuss
    Sponsored By: Dovetail Genomics
    5
    JUN 21, 2018 | 1:30 PM
    Pharmacogenetics in Psychiatry
    Pharmacogenetics in Psychiatry
    There is robust evidence supporting strong association with CYP450 (Phase 1) enzymes and influence on drug levels (affecting response & side effects in many cases) with many psychotropic...
    Speaker: Daniel Mueller, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    1
    JUN 21, 2018 | 12:00 PM
    Whole Genome Sequencing As A Valuable Clinical Tool For the Management of Cancer Patients
    Whole Genome Sequencing As A Valuable Clinical Tool For the Management...
    Advances in DNA sequencing, based upon massively parallel sequencing, has resulted in dramatic advances in DNA sequence output in the past few years. It is now possible to generate terrabases...
    Speaker: David Smith, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    1
    JUN 21, 2018 | 10:30 AM
    Setting Up Next-Generation Sequencing for the Needs of Routine Molecular Diagnostics With a Focus on the Suitability of the GeneReader NGS System for Lung Cancer Patients
    Setting Up Next-Generation Sequencing for the Needs of Routine...
    The introduction of targeted therapies into the clinical management of lung adenocarcinoma has had a massive impact on patient care. Multiple driver mutations are now druggable and treatments...
    Speaker: Paul Hofman, MD, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
     
     
  • JUN 21, 2018 | 9:00 AM
    Can AI Beat Cancer?
    Can AI Beat Cancer?
    Finding effective treatments for cancer is fundamentally  a high-dimensional probabilistic planning, search, and optimization problem, characterized by  thousands of molecular subty...
    Speaker: Marty Tenenbaum, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    1
    JUN 21, 2018 | 7:30 AM
    Keynote Presentation: Paving the Path Towards Precision Medicine in Inflammatory Bowel Diseases
    Keynote Presentation: Paving the Path Towards Precision Medicine...
    Crohn’s disease and ulcerative colitis also known as inflammatory bowel diseases or IBD, are characterized by chronic, recurrent inflammation of the gastrointestinal tract, which result...
    Speaker: Andres Hurtado-Lorenzo, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    1
    JUN 21, 2018 | 6:00 AM
    Rapid Whole Genome Sequencing in the NICU and PICU Decreases Infant Morbidity and Mortality
    Rapid Whole Genome Sequencing in the NICU and PICU Decreases Infant...
    Rare disease affects 30 million people in the United States, with nearly 50% of cases affecting children. Because nearly 80% of rare diseases are genetic, advancements in genomic testing are...
    Speaker: Stephen Kingsmore, PhD, MD
    Presented at: Precision Medicine Virtual Event Series 2018
    1
    JUN 20, 2018 | 1:30 PM
    Regulation of Precision Medicine
    Regulation of Precision Medicine
    Regulation of precision medicine is rapidly evolving.  The pre-existing regulatory framework did not contemplate many of the products and technologies which are becoming available with p...
    Speaker: Neil Belson
    Presented at: Precision Medicine Virtual Event Series 2018
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