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    CRISPR-Cas9

    CRISPR-Cas9: Clustered regularly interspaced short palindromic repeats are segments of prokaryotic DNA containing short, repetitive base sequences. These play a key role in a bacterial defence system,and form the basis of a genome editing technology known as CRISPR/Cas9 that allows permanent modification of genes within organisms. The CRISPR/Cas system is a prokaryotic immune system that confers resistance to foreign genetic elements such as those present within plasmids and phages that provides a form of acquired immunity. It is a unique technology that enables geneticists and medical researchers to edit parts of the genome by removing, adding or altering sections of the DNA sequence.

    Webinars

    • SEP 30, 2020 | 12:00 AM
      Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics
      Elucidation of remdesivir cytotoxicity pathways through genome-wide...
      The adenosine analogue remdesivir has emerged as a front-line antiviral treatment for SARS-CoV-2, with preliminary evidence that it reduces the duration and severity of illness. Prior clinic...
      Speaker: Minja Velimirovic, MSc, PhD Candidate
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 30, 2020 | 12:00 AM
      CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
      CRISPR/Cas9 as a tool to model and study cancer - insights and...
      Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
      Speaker: Grace R. Anderson, PhD
      Presented at: CRISPR Virtual Event Series 2020
      2
      SEP 30, 2020 | 12:00 AM
      Long-read sequencing reveals unforeseen CRISPR-Cas9 activity
      Long-read sequencing reveals unforeseen CRISPR-Cas9 activity
      An extensively debated concern about CRISPR-Cas9 genome editing is that unspecific guide RNA (gRNA) binding may induce off-target mutations. However, accurate prediction of CRISPR-Cas9 off-t...
      Speaker: Adam Ameur
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 30, 2020 | 12:00 AM
      Measuring Outcomes of CRISPR Experiments & Leveraging Cas9 for Targeted Sequencing
      Measuring Outcomes of CRISPR Experiments & Leveraging Cas9 for...
      CRISPR experiments are a powerful tool which are easy to carry out, however it is more difficult to determine the outcome of these experiments, and to ensure that only the desired targets we...
      Speaker: Jonas Korlach, PhD
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 17, 2020 | 8:00 AM
      Scalable Manufacturing and Nanovesicle Delivery of CRISPR-Cas9 Ribonucleoproteins Using a cGMP- Compliant Cell Engineering Platform
      Scalable Manufacturing and Nanovesicle Delivery of CRISPR-Cas9...
      DATE: September 17, 2020 TIME: 8:00am PT CRISPR-Cas9 has tremendous potential as a therapeutic tool for treating human diseases. However, prolonged expression of the nuclease and gRNA from v...
      Speaker: Peter Gee, Ph.D.
      Sponsored By: MaxCyte®
      6
      SEP 10, 2020 | 9:00 AM
      An Insider's Look: How One Parameter Can Optimize Key Phases of Bioprocessing Workflows
      An Insider's Look: How One Parameter Can Optimize Key Phases of...
      Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
      Speaker: Tara Barreira , Kristeena Wright
      Sponsored By: Advanced Instruments
      7
      SEP 03, 2020 | 9:00 AM
      The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
      The Complexities of SV Analytical Ultracentrifugation: AAVs are...
      DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
      Speaker: Dr. Lake Paul
      Sponsored By: Beckman Coulter Life Sciences
      12
      AUG 06, 2020 | 10:00 AM
      Part VI: Dissecting Cell Signaling Networks That Regulate Adult Neural Stem Cell Functions
      Part VI: Dissecting Cell Signaling Networks That Regulate Adult...
      In the adult mammalian hippocampus, neurogenesis (in which new neurons are generated and integrated into the CNS) is believed to underlie learning and memory. Within the hippocampus, numerou...
      Speaker: Kira Mosher, PhD
      Presented at: 2020 Beckman Symposium
      1
      JUN 18, 2020 | 9:00 AM
      Unveiling the role of T cell dysfunction in the development and progression of glioblastoma
      Unveiling the role of T cell dysfunction in the development and...
      DATE: June 18, 2020 TIME: 9:00am PDT, 12:00pm EDT Despite the success of immunotherapy against several malignancies including melanoma and lung adenocarcinoma, glioblastoma remains the excep...
      Speaker: Felipe Galvez Cancino, Ph.D.
      Sponsored By: Thermo Fisher Scientific/Gibco
      18 2
      JUN 02, 2020 | 7:00 AM
      Harnessing the Power of Protein Expression Systems in Vaccine Development
      Harnessing the Power of Protein Expression Systems in Vaccine...
      DATE: June 2, 2020 TIME: 7:00am PT, 10:00am ET In just a few months COVID-19 has risen from a regional crisis to a global threat, and drug makers are now scrambling to develop vaccines aimed...
      Speaker: Roland Leathers, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      15 1
      MAY 14, 2020 | 10:00 AM
      Massively Parallel Genome Engineering followed by pooled growth selections for rapid target discovery in microbes
      Massively Parallel Genome Engineering followed by pooled growth...
      DATE: May 14, 2020 TIME: 10:00am PT, 1:00pm ET Massively parallel genome engineering enables rapid and simultaneous evaluation of genotype-phenotype relationships at a genomic scale....
      Speaker: Stephen Federowicz, Ph.D.
      Sponsored By: Inscripta
      7
      MAY 14, 2020 | 4:15 PM
      Advantages and Challenges of Broad Molecular Profiling
      Advantages and Challenges of Broad Molecular Profiling
      The evolution of clinical trial design in oncology reflects the current clinical paradigm of personalized medicine, weighing both histology and molecularly-defined biomarkers as the pillars...
      Speaker: Ilaria Alborelli, PhD
      Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
      8
      MAY 14, 2020 | 4:15 PM
      Advantages and Challenges of Broad Molecular Profiling
      Advantages and Challenges of Broad Molecular Profiling
      The evolution of clinical trial design in oncology reflects the current clinical paradigm of personalized medicine, weighing both histology and molecularly-defined biomarkers as the pillars...
      Speaker: Ilaria Alborelli, PhD
      Presented at: OncomineWorld Autumn: A virtual NGS education meeting
      1
      MAY 14, 2020 | 1:00 AM
      Massively Parallel Genome Engineering followed by pooled growth selections for rapid target discovery in microbes
      Massively Parallel Genome Engineering followed by pooled growth...
      DATE: May 14, 2020 TIME: 10:00am CEST Massively parallel genome engineering enables rapid and simultaneous evaluation of genotype-phenotype relationships at a genomic scale. With the Inscrip...
      Speaker: Laura Klitten, Ph.D.
      Sponsored By: Inscripta
      6
      APR 30, 2020 | 9:00 AM
      Tools and methods for CRISPR-Cas9 screening for functional genomics and drug discovery
      Tools and methods for CRISPR-Cas9 screening for functional genomics...
      DATE: April 30, 2020 TIME: 9:00am PT, 12:00pm ET Loss-of-function studies are an established method for uncovering a gene’s role in a biological pathway or disease state. The advent of...
      Speaker: Louise Baskin, M.S. Molecular Biology and Genetics
      Sponsored By: Thermo Fisher Scientific
      23 1
      APR 22, 2020 | 6:00 AM
      Improved Genome Editing Using Single-Stranded DNA
      Improved Genome Editing Using Single-Stranded DNA
      CRISPR-Cas9 gene editing is a powerful technique that enables genetic modification with greater speed and accuracy than previous approaches. In this webinar, Dr. Chen highlights the advantag...
      Speaker: Ye Chen, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      Sponsored By: GENEWIZ
      1
      APR 21, 2020 | 7:30 AM
      Novel CRISPR Knock-In Technology for the Robust Analysis of Cells and Tissue
      Novel CRISPR Knock-In Technology for the Robust Analysis of Cells...
      Modern biomedical research is being driven by large scale genetic and proteomic research to identify new targets for the study of disease mechanisms. While these techniques have been incredi...
      Speaker: Scott Soderling, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      Sponsored By: CasTag Biosciences
      1 1
      APR 14, 2020 | 9:00 AM
      Gibco Cell Culture Heroes: Work From Home Edition
      Gibco Cell Culture Heroes: Work From Home Edition
      DATE: April 14, 2020 TIME: 9:00am PDT, 12:00pm EDT Besides being Gibco Cell Culture Heroes, what do Vivek, Sandra, Daisy, Ameet and Kristine all have in common? They are all stuck at home fo...
      Speaker: Kristine Wadosky, PhD , Ameet Chimote, PhD , Elizabeth Delery, PhD , Daisy Shu, B.Optom, PhD , Vivek Kamat, PhD , Sandra Hammer, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      12 1
      APR 08, 2020 | 12:00 AM
      Directed Evolution of Next-Generation AAV Vector Systems for Clinical Gene Therapy
      Directed Evolution of Next-Generation AAV Vector Systems for Clinical...
      There has been an increasing number of successful gene therapy clinical trials, leading to regulatory approvals of numerous gene therapy products, in particular ones based on the adeno-assoc...
      Speaker: David Schaffer, PhD
      Presented at: BioProcessing Virtual Event Series 2020
      2
      APR 07, 2020 | 8:00 AM
      Best Practice Criteria for Pluripotent Stem Cell Lines
      Best Practice Criteria for Pluripotent Stem Cell Lines
      DATE: April 7, 2020 TIME: 8:00am PT, 11:00am ET This webinar sets out to establish why quality control is key to robust, reliable, reproducible science. We will look at best practice criteri...
      Speaker: Lyn Healy
      Sponsored By: STEMCELL Technologies
      22
      MAR 31, 2020 | 7:00 AM
      Investigation of NK cell-driven tumor immunity using novel image cytometry detection method
      Investigation of NK cell-driven tumor immunity using novel image...
      DATE: March 31, 2020 TIME: 7:00am PT, 10:00am PT Please join us for this webinar, during which we will present and discuss the promotion of NK cell-driven tumor immunity. In addition, we wil...
      Speaker: Lucas Ferrari de Andrade, Ph.D. , Leo Chan, Ph.D.
      Sponsored By: Nexcelom Bioscience
      10
      MAR 27, 2020 | 9:00 AM
      Modified Dental Composite for Bone Repair
      Modified Dental Composite for Bone Repair
      DATE: March 27, 2020 TIME: 9:00am PDT, 12:00pm EDT Osteoporosis causes a decrease in bone density, along with deterioration of the bone’s microarchitecture at a faster rate than normal...
      Speaker: Mayda Arshad
      Sponsored By: Thermo Fisher Scientific/Gibco
      11
      MAR 26, 2020 | 9:00 AM
      Cutting Edge Viral and Non-Viral Delivery Platforms for T-Cell Engineering and Beyond
      Cutting Edge Viral and Non-Viral Delivery Platforms for T-Cell...
      DATE: March 26, 2020 TIME: 9:00am PST, 12:00pm EST Growing demand for precision therapy and the recent successes with CAR-T cells for cancer treatment...
      Speaker: Namritha Ravinder
      Sponsored By: Thermo Fisher Scientific
      7
      MAR 03, 2020 | 8:00 AM
      A benchtop platform for massively parallel CRISPR-based microbial genome engineering
      A benchtop platform for massively parallel CRISPR-based microbial...
      DATE: March 3, 2020 TIME: 8:00am PT, 11:00am ET CRISPR-based genome engineering tools are currently revolutionizing the rate of biological discovery in academic and industrial settings world...
      Speaker: Daniel Held, Ph.D.
      Sponsored By: Inscripta
      7
    SEP 30, 2020 | 12:00 AM
    Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics
    Elucidation of remdesivir cytotoxicity pathways through genome-wide...
    The adenosine analogue remdesivir has emerged as a front-line antiviral treatment for SARS-CoV-2, with preliminary evidence that it reduces the duration and severity of illness. Prior clinic...
    Speaker: Minja Velimirovic, MSc, PhD Candidate
    Presented at: CRISPR Virtual Event Series 2020
    1
    SEP 30, 2020 | 12:00 AM
    CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
    CRISPR/Cas9 as a tool to model and study cancer - insights and...
    Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
    Speaker: Grace R. Anderson, PhD
    Presented at: CRISPR Virtual Event Series 2020
    2
    SEP 30, 2020 | 12:00 AM
    Long-read sequencing reveals unforeseen CRISPR-Cas9 activity
    Long-read sequencing reveals unforeseen CRISPR-Cas9 activity
    An extensively debated concern about CRISPR-Cas9 genome editing is that unspecific guide RNA (gRNA) binding may induce off-target mutations. However, accurate prediction of CRISPR-Cas9 off-t...
    Speaker: Adam Ameur
    Presented at: CRISPR Virtual Event Series 2020
    1
    SEP 30, 2020 | 12:00 AM
    Measuring Outcomes of CRISPR Experiments & Leveraging Cas9 for Targeted Sequencing
    Measuring Outcomes of CRISPR Experiments & Leveraging Cas9 for...
    CRISPR experiments are a powerful tool which are easy to carry out, however it is more difficult to determine the outcome of these experiments, and to ensure that only the desired targets we...
    Speaker: Jonas Korlach, PhD
    Presented at: CRISPR Virtual Event Series 2020
    1
    SEP 17, 2020 | 8:00 AM
    Scalable Manufacturing and Nanovesicle Delivery of CRISPR-Cas9 Ribonucleoproteins Using a cGMP- Compliant Cell Engineering Platform
    Scalable Manufacturing and Nanovesicle Delivery of CRISPR-Cas9...
    DATE: September 17, 2020 TIME: 8:00am PT CRISPR-Cas9 has tremendous potential as a therapeutic tool for treating human diseases. However, prolonged expression of the nuclease and gRNA from v...
    Speaker: Peter Gee, Ph.D.
    Sponsored By: MaxCyte®
    6
     
     
  • SEP 10, 2020 | 9:00 AM
    An Insider's Look: How One Parameter Can Optimize Key Phases of Bioprocessing Workflows
    An Insider's Look: How One Parameter Can Optimize Key Phases of...
    Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
    Speaker: Tara Barreira , Kristeena Wright
    Sponsored By: Advanced Instruments
    7
    SEP 03, 2020 | 9:00 AM
    The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
    The Complexities of SV Analytical Ultracentrifugation: AAVs are...
    DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
    Speaker: Dr. Lake Paul
    Sponsored By: Beckman Coulter Life Sciences
    12
    AUG 06, 2020 | 10:00 AM
    Part VI: Dissecting Cell Signaling Networks That Regulate Adult Neural Stem Cell Functions
    Part VI: Dissecting Cell Signaling Networks That Regulate Adult...
    In the adult mammalian hippocampus, neurogenesis (in which new neurons are generated and integrated into the CNS) is believed to underlie learning and memory. Within the hippocampus, numerou...
    Speaker: Kira Mosher, PhD
    Presented at: 2020 Beckman Symposium
    1
    JUN 18, 2020 | 9:00 AM
    Unveiling the role of T cell dysfunction in the development and progression of glioblastoma
    Unveiling the role of T cell dysfunction in the development and...
    DATE: June 18, 2020 TIME: 9:00am PDT, 12:00pm EDT Despite the success of immunotherapy against several malignancies including melanoma and lung adenocarcinoma, glioblastoma remains the excep...
    Speaker: Felipe Galvez Cancino, Ph.D.
    Sponsored By: Thermo Fisher Scientific/Gibco
    18 2
    JUN 02, 2020 | 7:00 AM
    Harnessing the Power of Protein Expression Systems in Vaccine Development
    Harnessing the Power of Protein Expression Systems in Vaccine...
    DATE: June 2, 2020 TIME: 7:00am PT, 10:00am ET In just a few months COVID-19 has risen from a regional crisis to a global threat, and drug makers are now scrambling to develop vaccines aimed...
    Speaker: Roland Leathers, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    15 1
     
     
  • MAY 14, 2020 | 10:00 AM
    Massively Parallel Genome Engineering followed by pooled growth selections for rapid target discovery in microbes
    Massively Parallel Genome Engineering followed by pooled growth...
    DATE: May 14, 2020 TIME: 10:00am PT, 1:00pm ET Massively parallel genome engineering enables rapid and simultaneous evaluation of genotype-phenotype relationships at a genomic scale....
    Speaker: Stephen Federowicz, Ph.D.
    Sponsored By: Inscripta
    7
    MAY 14, 2020 | 4:15 PM
    Advantages and Challenges of Broad Molecular Profiling
    Advantages and Challenges of Broad Molecular Profiling
    The evolution of clinical trial design in oncology reflects the current clinical paradigm of personalized medicine, weighing both histology and molecularly-defined biomarkers as the pillars...
    Speaker: Ilaria Alborelli, PhD
    Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
    8
    MAY 14, 2020 | 4:15 PM
    Advantages and Challenges of Broad Molecular Profiling
    Advantages and Challenges of Broad Molecular Profiling
    The evolution of clinical trial design in oncology reflects the current clinical paradigm of personalized medicine, weighing both histology and molecularly-defined biomarkers as the pillars...
    Speaker: Ilaria Alborelli, PhD
    Presented at: OncomineWorld Autumn: A virtual NGS education meeting
    1
    MAY 14, 2020 | 1:00 AM
    Massively Parallel Genome Engineering followed by pooled growth selections for rapid target discovery in microbes
    Massively Parallel Genome Engineering followed by pooled growth...
    DATE: May 14, 2020 TIME: 10:00am CEST Massively parallel genome engineering enables rapid and simultaneous evaluation of genotype-phenotype relationships at a genomic scale. With the Inscrip...
    Speaker: Laura Klitten, Ph.D.
    Sponsored By: Inscripta
    6
    APR 30, 2020 | 9:00 AM
    Tools and methods for CRISPR-Cas9 screening for functional genomics and drug discovery
    Tools and methods for CRISPR-Cas9 screening for functional genomics...
    DATE: April 30, 2020 TIME: 9:00am PT, 12:00pm ET Loss-of-function studies are an established method for uncovering a gene’s role in a biological pathway or disease state. The advent of...
    Speaker: Louise Baskin, M.S. Molecular Biology and Genetics
    Sponsored By: Thermo Fisher Scientific
    23 1
     
     
  • APR 22, 2020 | 6:00 AM
    Improved Genome Editing Using Single-Stranded DNA
    Improved Genome Editing Using Single-Stranded DNA
    CRISPR-Cas9 gene editing is a powerful technique that enables genetic modification with greater speed and accuracy than previous approaches. In this webinar, Dr. Chen highlights the advantag...
    Speaker: Ye Chen, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    Sponsored By: GENEWIZ
    1
    APR 21, 2020 | 7:30 AM
    Novel CRISPR Knock-In Technology for the Robust Analysis of Cells and Tissue
    Novel CRISPR Knock-In Technology for the Robust Analysis of Cells...
    Modern biomedical research is being driven by large scale genetic and proteomic research to identify new targets for the study of disease mechanisms. While these techniques have been incredi...
    Speaker: Scott Soderling, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    Sponsored By: CasTag Biosciences
    1 1
    APR 14, 2020 | 9:00 AM
    Gibco Cell Culture Heroes: Work From Home Edition
    Gibco Cell Culture Heroes: Work From Home Edition
    DATE: April 14, 2020 TIME: 9:00am PDT, 12:00pm EDT Besides being Gibco Cell Culture Heroes, what do Vivek, Sandra, Daisy, Ameet and Kristine all have in common? They are all stuck at home fo...
    Speaker: Kristine Wadosky, PhD , Ameet Chimote, PhD , Elizabeth Delery, PhD , Daisy Shu, B.Optom, PhD , Vivek Kamat, PhD , Sandra Hammer, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    12 1
    APR 08, 2020 | 12:00 AM
    Directed Evolution of Next-Generation AAV Vector Systems for Clinical Gene Therapy
    Directed Evolution of Next-Generation AAV Vector Systems for Clinical...
    There has been an increasing number of successful gene therapy clinical trials, leading to regulatory approvals of numerous gene therapy products, in particular ones based on the adeno-assoc...
    Speaker: David Schaffer, PhD
    Presented at: BioProcessing Virtual Event Series 2020
    2
    APR 07, 2020 | 8:00 AM
    Best Practice Criteria for Pluripotent Stem Cell Lines
    Best Practice Criteria for Pluripotent Stem Cell Lines
    DATE: April 7, 2020 TIME: 8:00am PT, 11:00am ET This webinar sets out to establish why quality control is key to robust, reliable, reproducible science. We will look at best practice criteri...
    Speaker: Lyn Healy
    Sponsored By: STEMCELL Technologies
    22
     
     
  • MAR 31, 2020 | 7:00 AM
    Investigation of NK cell-driven tumor immunity using novel image cytometry detection method
    Investigation of NK cell-driven tumor immunity using novel image...
    DATE: March 31, 2020 TIME: 7:00am PT, 10:00am PT Please join us for this webinar, during which we will present and discuss the promotion of NK cell-driven tumor immunity. In addition, we wil...
    Speaker: Lucas Ferrari de Andrade, Ph.D. , Leo Chan, Ph.D.
    Sponsored By: Nexcelom Bioscience
    10
    MAR 27, 2020 | 9:00 AM
    Modified Dental Composite for Bone Repair
    Modified Dental Composite for Bone Repair
    DATE: March 27, 2020 TIME: 9:00am PDT, 12:00pm EDT Osteoporosis causes a decrease in bone density, along with deterioration of the bone’s microarchitecture at a faster rate than normal...
    Speaker: Mayda Arshad
    Sponsored By: Thermo Fisher Scientific/Gibco
    11
    MAR 26, 2020 | 9:00 AM
    Cutting Edge Viral and Non-Viral Delivery Platforms for T-Cell Engineering and Beyond
    Cutting Edge Viral and Non-Viral Delivery Platforms for T-Cell...
    DATE: March 26, 2020 TIME: 9:00am PST, 12:00pm EST Growing demand for precision therapy and the recent successes with CAR-T cells for cancer treatment...
    Speaker: Namritha Ravinder
    Sponsored By: Thermo Fisher Scientific
    7
    MAR 03, 2020 | 8:00 AM
    A benchtop platform for massively parallel CRISPR-based microbial genome engineering
    A benchtop platform for massively parallel CRISPR-based microbial...
    DATE: March 3, 2020 TIME: 8:00am PT, 11:00am ET CRISPR-based genome engineering tools are currently revolutionizing the rate of biological discovery in academic and industrial settings world...
    Speaker: Daniel Held, Ph.D.
    Sponsored By: Inscripta
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