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    CRISPR-Cas9

    CRISPR-Cas9: Clustered regularly interspaced short palindromic repeats are segments of prokaryotic DNA containing short, repetitive base sequences. These play a key role in a bacterial defence system,and form the basis of a genome editing technology known as CRISPR/Cas9 that allows permanent modification of genes within organisms. The CRISPR/Cas system is a prokaryotic immune system that confers resistance to foreign genetic elements such as those present within plasmids and phages that provides a form of acquired immunity. It is a unique technology that enables geneticists and medical researchers to edit parts of the genome by removing, adding or altering sections of the DNA sequence.

    Webinars

    • FEB 26, 2020 | 9:00 AM
      CRISPR Based Screening: Advantages of Transcriptional Activators and Inhibitors
      CRISPR Based Screening: Advantages of Transcriptional Activators...
      CRISPR revolutionized gene editing, but multi-target screening remains a complex goal. In addition, the fast pace of CRISPR technology development has brought sophisticated options for libra...
      Speaker: Andrew Ravanelli, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      2 1
      JAN 30, 2020 | 9:00 AM
      An Automated Cancer Organoid Culture Platform to Accelerate Research and Drug Screening
      An Automated Cancer Organoid Culture Platform to Accelerate Research...
      DATE: January 30, 2020 TIME: 9:00am PST, 12:00pm EST Recent advances in in vitro 3D cellular culture technologies, such as organoids, rapidly developed and established novel, more physiologi...
      Speaker: Brooke Schuster
      Sponsored By: Thermo Fisher Scientific/Gibco
      10
      JAN 23, 2020 | 9:00 AM
      A Workflow for Knock-in Genome Editing: Simplified
      A Workflow for Knock-in Genome Editing: Simplified
      DATE: January 23, 2020 TIME: 9:00am PST, 12:00pm EST...
      Speaker: Matthew Poling, PhD
      Sponsored By: Thermo Fisher Scientific
      17
      JAN 09, 2020 | 10:00 AM
      Engineering the hematopoietic system to treat non-hematological disorders
      Engineering the hematopoietic system to treat non-hematological...
      Join us on January 9, 2020 for this live webinar!...
      Speaker: Natalia Gomez-Ospina, PhD
      Sponsored By: STEMCELL Technologies
      10
      JAN 01, 2020 | 6:00 AM
      Uncovering the mechanism of stress-resistant DNA replication in cancer cells using a modern single-molecule technique
      Uncovering the mechanism of stress-resistant DNA replication in...
      Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
      Speaker: Chames Kermi, PhD, PharmD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      DEC 17, 2019 | 9:00 AM
      The role of SIRT1/LXR signaling in diabetic retinopathy
      The role of SIRT1/LXR signaling in diabetic retinopathy
      DATE: December 17, 2019TIME: 9:00am PST, 12:00pm EST Purpose: Liver x receptors (LXRs) are hypothesized to serve as a link between lipid metabolism and inflammation by prom...
      Speaker: Sandra Hammer, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      DEC 04, 2019 | 7:00 AM
      Improve your reproducibility - Liquid Handling is a crucial factor Exemplarily shown for NGS, ELISA and qPCR
      Improve your reproducibility - Liquid Handling is a crucial factor...
      DATE: December 4, 2019TIME: 7:00am PST, 10:00am EST, 4:00pm CET Do you know how it feels when you just quickly want to redo an experiment that your colleague did, or an experim...
      Speaker: Katja Baesler, PhD , Ulrike Gast, PhD , Alisa Gruschka
      Sponsored By: Eppendorf
      12
      NOV 21, 2019 | 9:00 AM
      The role of immune cells and immune checkpoints in multiple myeloma
      The role of immune cells and immune checkpoints in multiple myeloma
      DATE: November 21, 2019TIME: 9:00am PST, 12:00pm EST Multiple Myeloma is a disease of terminally differentiated plasma cells with the massive production of monoclonal immunoglobu...
      Speaker: Nathalie Heider-Hönatsch, M.Sc.
      Sponsored By: Thermo Fisher Scientific/Gibco
      11
      NOV 18, 2019 | 7:00 AM
      Protect your cells with proper pipetting - How liquid handling influences your cell culture work
      Protect your cells with proper pipetting - How liquid handling...
      DATE: November 18, 2019TIME: 7:00am PST, 11:00am EST, 4:00pm CEWT How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop th...
      Speaker: Nadine Mellies, PhD , Katja Baesler, PhD
      Sponsored By: Eppendorf
      22 2
      OCT 31, 2019 | 9:00 AM
      Investigation of Endothelial Cell Viability and Growth on 3D printed GelMa Vascular Networks
      Investigation of Endothelial Cell Viability and Growth on 3D printed...
      DATE: October 31, 2019TIME: 9:00am PDT, 12:00pm EDT INTRODUCTION: A major limitation for the development of 3D engineered tissues is the absence of viable and perfusable...
      Speaker: Chrisoula Chappell
      Sponsored By: Thermo Fisher Scientific/Gibco
      8
      OCT 10, 2019 | 6:00 AM
      Highly-efficient and -specific genome editing with Cas9 nickase ribonucleoproteins in Primary T-cells
      Highly-efficient and -specific genome editing with Cas9 nickase...
      In this webinar, we will be discussing some of our most recent testing using our Cas9 proteins, Cas9 RNP nickases in a variety of human cell types, including primary T-cells. Cas nucleases wh...
      Speaker: Jacob Lamberth
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      Sponsored By: MilliporeSigma
      1
      OCT 03, 2019 | 3:00 PM
      'Any Idiot can do it'.  How easy a knockout or knockin mouse could be generated using CRISPR/Cas9 gene editing technology?
      'Any Idiot can do it'. How easy a knockout or knockin mouse could...
      Novel precision genetic technologies such as CRISPR/Cas9 genome editing technology offer novel avenues to a better understanding the mechanisms of diseases. Using CRISPR/Cas9 we are able to p...
      Speaker: Gaetan Burgio, Msc, MBBS, MD, PhD
      Presented at: CRISPR Virtual Event Series 2019
      3
      OCT 03, 2019 | 1:30 PM
      Application of Genome Editing for Improving Banana with Disease Resistance
      Application of Genome Editing for Improving Banana with Disease...
      Banana (Musa spp.) is one of the major staple food crops grown in over 140 countries in the subtropics and tropics with annual global production of around 148 million metric, feeding about 50...
      Speaker: Leena Tripathi, PhD
      Presented at: CRISPR Virtual Event Series 2019
      1
      OCT 03, 2019 | 12:00 PM
      Gene Editing Success: Considerations for maximizing your CRISPR gene editing accuracy and efficiency
      Gene Editing Success: Considerations for maximizing your CRISPR...
      CRISPR based gene editing has proven to be an incredibly powerful tool for studying functions of individual proteins, understanding the role of multi-gene pathways, and even knocking out prot...
      Speaker: Ryan Donnelly
      Presented at: CRISPR Virtual Event Series 2019
      Sponsored By: Horizon Discovery
      2
      OCT 03, 2019 | 10:30 AM
      Experimenting on future children: How do early adopters shape the ethics and regulation of new technologies?
      Experimenting on future children: How do early adopters shape...
      While CRISPR-Cas9 has dominated the science headlines in recent years, there has been a broad social and moral consensus that it is too soon to move to clinical use of genome editing in human...
      Speaker: Catherine Mills, PhD
      Presented at: CRISPR Virtual Event Series 2019
      1
      OCT 03, 2019 | 9:00 AM
      Structures of CRISPR-Cas surveillance complexes
      Structures of CRISPR-Cas surveillance complexes
      CRISPR (clustered regularly interspaced short palindromic repeats) RNA and CRISPR-associated genes (Cas) assemble into RNA-guided surveillance complex that targets foreign nucleic acids for d...
      Speaker: David Taylor, PhD
      Presented at: CRISPR Virtual Event Series 2019
      1
      OCT 03, 2019 | 9:00 AM
      Application of CRISPR-Cas9 in plants
      Application of CRISPR-Cas9 in plants
      CRISPR-Cas9 based gene editing is a powerful tool which can induce heritable mutations at desired genomic loci without leaving transgenic trace in plants. Here we constructed a robust, multip...
      Speaker: Xing-Liang Ma, PhD
      Presented at: CRISPR Virtual Event Series 2019
      2
      OCT 03, 2019 | 7:30 AM
      Keynote Presentation: CRISPR/Cas9 genome editing in mouse and rat: The PHENOMIN-ICS experience
      Keynote Presentation: CRISPR/Cas9 genome editing in mouse and...
      CRISPR/Cas9 technology has become very popular in the last 5 years and has profoundly changed our way to do genetically engineered animals. I will present the latest development in genome edi...
      Speaker: Marie-Christine Birling, PhD
      Presented at: CRISPR Virtual Event Series 2019
      1
      OCT 03, 2019 | 6:00 AM
      CRISPR/Cas9 technology and insect population control
      CRISPR/Cas9 technology and insect population control
      Insects are the largest and most diverse arthropod group. Many insect species are agricultural pests or vectors of numerous diseases. In fact, the mosquito is the deadliest animal on the eart...
      Speaker: Nikolay Kandul, PhD
      Presented at: CRISPR Virtual Event Series 2019
      4
      OCT 03, 2019 | 6:00 AM
      CRISPR Regulations: Rewriting DNA and Rethinking GMOs
      CRISPR Regulations: Rewriting DNA and Rethinking GMOs
      First discovered as a genome-editing tool just seven years ago, CRISPR systems have already changed the face of basic research, allowing researchers to alter the DNA of hundreds of organisms...
      Speaker: Lea Witkowsky, PhD
      Presented at: CRISPR Virtual Event Series 2019
      5
      SEP 05, 2019 | 7:00 AM
      The bread and butter method of genomics: How to improve your (q)PCR
      The bread and butter method of genomics: How to improve your (q)PCR
      DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
      Speaker: Tim Schommartz, PhD
      Sponsored By: Eppendorf
      17 1
      AUG 13, 2019 | 9:00 AM
      Nanometer-accuracy distance measurements between fluorophores at the single-molecule level
      Nanometer-accuracy distance measurements between fluorophores...
      DATE: August 13, 2019TIME: 9:00am PT, 12:00pm ET, 5:00pm BST Molecular complexes are major constituents of cells, hence unraveling their mechanisms is key to fuller comprehension of c...
      Speaker: Nico Stuurman, PhD , Marcin Barszczewski, PhD
      Sponsored By: Andor
      3
      JUN 19, 2019 | 11:00 AM
      Selecting the right tools to build your pluripotent stem cell based disease models
      Selecting the right tools to build your pluripotent stem cell...
      DATE: June 19, 2019TIME: 11:00am PDT, 2:00pm EDT Abstract:...
      Speaker: Erik Willems, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      3
      JUN 19, 2019 | 10:00 AM
      Getting started in 3D:  Ask an Expert
      Getting started in 3D: Ask an Expert
      DATE: June 19, 2019TIME: 10:00am PDT, 1:00pm EDT As we develop new methods to create more biologically relevant models for research in understanding disease etiology and in...
      Speaker: Mark Kennedy, Ph.D. , Richard Josephson, PhD
      Sponsored By: Thermo Fisher Scientific
      6
    FEB 26, 2020 | 9:00 AM
    CRISPR Based Screening: Advantages of Transcriptional Activators and Inhibitors
    CRISPR Based Screening: Advantages of Transcriptional Activators...
    CRISPR revolutionized gene editing, but multi-target screening remains a complex goal. In addition, the fast pace of CRISPR technology development has brought sophisticated options for libra...
    Speaker: Andrew Ravanelli, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    2 1
    JAN 30, 2020 | 9:00 AM
    An Automated Cancer Organoid Culture Platform to Accelerate Research and Drug Screening
    An Automated Cancer Organoid Culture Platform to Accelerate Research...
    DATE: January 30, 2020 TIME: 9:00am PST, 12:00pm EST Recent advances in in vitro 3D cellular culture technologies, such as organoids, rapidly developed and established novel, more physiologi...
    Speaker: Brooke Schuster
    Sponsored By: Thermo Fisher Scientific/Gibco
    10
    JAN 23, 2020 | 9:00 AM
    A Workflow for Knock-in Genome Editing: Simplified
    A Workflow for Knock-in Genome Editing: Simplified
    DATE: January 23, 2020 TIME: 9:00am PST, 12:00pm EST...
    Speaker: Matthew Poling, PhD
    Sponsored By: Thermo Fisher Scientific
    17
    JAN 09, 2020 | 10:00 AM
    Engineering the hematopoietic system to treat non-hematological disorders
    Engineering the hematopoietic system to treat non-hematological...
    Join us on January 9, 2020 for this live webinar!...
    Speaker: Natalia Gomez-Ospina, PhD
    Sponsored By: STEMCELL Technologies
    10
    JAN 01, 2020 | 6:00 AM
    Uncovering the mechanism of stress-resistant DNA replication in cancer cells using a modern single-molecule technique
    Uncovering the mechanism of stress-resistant DNA replication in...
    Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
    Speaker: Chames Kermi, PhD, PharmD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
     
     
  • DEC 17, 2019 | 9:00 AM
    The role of SIRT1/LXR signaling in diabetic retinopathy
    The role of SIRT1/LXR signaling in diabetic retinopathy
    DATE: December 17, 2019TIME: 9:00am PST, 12:00pm EST Purpose: Liver x receptors (LXRs) are hypothesized to serve as a link between lipid metabolism and inflammation by prom...
    Speaker: Sandra Hammer, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
    DEC 04, 2019 | 7:00 AM
    Improve your reproducibility - Liquid Handling is a crucial factor Exemplarily shown for NGS, ELISA and qPCR
    Improve your reproducibility - Liquid Handling is a crucial factor...
    DATE: December 4, 2019TIME: 7:00am PST, 10:00am EST, 4:00pm CET Do you know how it feels when you just quickly want to redo an experiment that your colleague did, or an experim...
    Speaker: Katja Baesler, PhD , Ulrike Gast, PhD , Alisa Gruschka
    Sponsored By: Eppendorf
    12
    NOV 21, 2019 | 9:00 AM
    The role of immune cells and immune checkpoints in multiple myeloma
    The role of immune cells and immune checkpoints in multiple myeloma
    DATE: November 21, 2019TIME: 9:00am PST, 12:00pm EST Multiple Myeloma is a disease of terminally differentiated plasma cells with the massive production of monoclonal immunoglobu...
    Speaker: Nathalie Heider-Hönatsch, M.Sc.
    Sponsored By: Thermo Fisher Scientific/Gibco
    11
    NOV 18, 2019 | 7:00 AM
    Protect your cells with proper pipetting - How liquid handling influences your cell culture work
    Protect your cells with proper pipetting - How liquid handling...
    DATE: November 18, 2019TIME: 7:00am PST, 11:00am EST, 4:00pm CEWT How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop th...
    Speaker: Nadine Mellies, PhD , Katja Baesler, PhD
    Sponsored By: Eppendorf
    22 2
    OCT 31, 2019 | 9:00 AM
    Investigation of Endothelial Cell Viability and Growth on 3D printed GelMa Vascular Networks
    Investigation of Endothelial Cell Viability and Growth on 3D printed...
    DATE: October 31, 2019TIME: 9:00am PDT, 12:00pm EDT INTRODUCTION: A major limitation for the development of 3D engineered tissues is the absence of viable and perfusable...
    Speaker: Chrisoula Chappell
    Sponsored By: Thermo Fisher Scientific/Gibco
    8
     
     
  • OCT 10, 2019 | 6:00 AM
    Highly-efficient and -specific genome editing with Cas9 nickase ribonucleoproteins in Primary T-cells
    Highly-efficient and -specific genome editing with Cas9 nickase...
    In this webinar, we will be discussing some of our most recent testing using our Cas9 proteins, Cas9 RNP nickases in a variety of human cell types, including primary T-cells. Cas nucleases wh...
    Speaker: Jacob Lamberth
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    Sponsored By: MilliporeSigma
    1
    OCT 03, 2019 | 3:00 PM
    'Any Idiot can do it'.  How easy a knockout or knockin mouse could be generated using CRISPR/Cas9 gene editing technology?
    'Any Idiot can do it'. How easy a knockout or knockin mouse could...
    Novel precision genetic technologies such as CRISPR/Cas9 genome editing technology offer novel avenues to a better understanding the mechanisms of diseases. Using CRISPR/Cas9 we are able to p...
    Speaker: Gaetan Burgio, Msc, MBBS, MD, PhD
    Presented at: CRISPR Virtual Event Series 2019
    3
    OCT 03, 2019 | 1:30 PM
    Application of Genome Editing for Improving Banana with Disease Resistance
    Application of Genome Editing for Improving Banana with Disease...
    Banana (Musa spp.) is one of the major staple food crops grown in over 140 countries in the subtropics and tropics with annual global production of around 148 million metric, feeding about 50...
    Speaker: Leena Tripathi, PhD
    Presented at: CRISPR Virtual Event Series 2019
    1
    OCT 03, 2019 | 12:00 PM
    Gene Editing Success: Considerations for maximizing your CRISPR gene editing accuracy and efficiency
    Gene Editing Success: Considerations for maximizing your CRISPR...
    CRISPR based gene editing has proven to be an incredibly powerful tool for studying functions of individual proteins, understanding the role of multi-gene pathways, and even knocking out prot...
    Speaker: Ryan Donnelly
    Presented at: CRISPR Virtual Event Series 2019
    Sponsored By: Horizon Discovery
    2
    OCT 03, 2019 | 10:30 AM
    Experimenting on future children: How do early adopters shape the ethics and regulation of new technologies?
    Experimenting on future children: How do early adopters shape...
    While CRISPR-Cas9 has dominated the science headlines in recent years, there has been a broad social and moral consensus that it is too soon to move to clinical use of genome editing in human...
    Speaker: Catherine Mills, PhD
    Presented at: CRISPR Virtual Event Series 2019
    1
     
     
  • OCT 03, 2019 | 9:00 AM
    Structures of CRISPR-Cas surveillance complexes
    Structures of CRISPR-Cas surveillance complexes
    CRISPR (clustered regularly interspaced short palindromic repeats) RNA and CRISPR-associated genes (Cas) assemble into RNA-guided surveillance complex that targets foreign nucleic acids for d...
    Speaker: David Taylor, PhD
    Presented at: CRISPR Virtual Event Series 2019
    1
    OCT 03, 2019 | 9:00 AM
    Application of CRISPR-Cas9 in plants
    Application of CRISPR-Cas9 in plants
    CRISPR-Cas9 based gene editing is a powerful tool which can induce heritable mutations at desired genomic loci without leaving transgenic trace in plants. Here we constructed a robust, multip...
    Speaker: Xing-Liang Ma, PhD
    Presented at: CRISPR Virtual Event Series 2019
    2
    OCT 03, 2019 | 7:30 AM
    Keynote Presentation: CRISPR/Cas9 genome editing in mouse and rat: The PHENOMIN-ICS experience
    Keynote Presentation: CRISPR/Cas9 genome editing in mouse and...
    CRISPR/Cas9 technology has become very popular in the last 5 years and has profoundly changed our way to do genetically engineered animals. I will present the latest development in genome edi...
    Speaker: Marie-Christine Birling, PhD
    Presented at: CRISPR Virtual Event Series 2019
    1
    OCT 03, 2019 | 6:00 AM
    CRISPR/Cas9 technology and insect population control
    CRISPR/Cas9 technology and insect population control
    Insects are the largest and most diverse arthropod group. Many insect species are agricultural pests or vectors of numerous diseases. In fact, the mosquito is the deadliest animal on the eart...
    Speaker: Nikolay Kandul, PhD
    Presented at: CRISPR Virtual Event Series 2019
    4
    OCT 03, 2019 | 6:00 AM
    CRISPR Regulations: Rewriting DNA and Rethinking GMOs
    CRISPR Regulations: Rewriting DNA and Rethinking GMOs
    First discovered as a genome-editing tool just seven years ago, CRISPR systems have already changed the face of basic research, allowing researchers to alter the DNA of hundreds of organisms...
    Speaker: Lea Witkowsky, PhD
    Presented at: CRISPR Virtual Event Series 2019
    5
     
     
  • SEP 05, 2019 | 7:00 AM
    The bread and butter method of genomics: How to improve your (q)PCR
    The bread and butter method of genomics: How to improve your (q)PCR
    DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
    Speaker: Tim Schommartz, PhD
    Sponsored By: Eppendorf
    17 1
    AUG 13, 2019 | 9:00 AM
    Nanometer-accuracy distance measurements between fluorophores at the single-molecule level
    Nanometer-accuracy distance measurements between fluorophores...
    DATE: August 13, 2019TIME: 9:00am PT, 12:00pm ET, 5:00pm BST Molecular complexes are major constituents of cells, hence unraveling their mechanisms is key to fuller comprehension of c...
    Speaker: Nico Stuurman, PhD , Marcin Barszczewski, PhD
    Sponsored By: Andor
    3
    JUN 19, 2019 | 11:00 AM
    Selecting the right tools to build your pluripotent stem cell based disease models
    Selecting the right tools to build your pluripotent stem cell...
    DATE: June 19, 2019TIME: 11:00am PDT, 2:00pm EDT Abstract:...
    Speaker: Erik Willems, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    3
    JUN 19, 2019 | 10:00 AM
    Getting started in 3D:  Ask an Expert
    Getting started in 3D: Ask an Expert
    DATE: June 19, 2019TIME: 10:00am PDT, 1:00pm EDT As we develop new methods to create more biologically relevant models for research in understanding disease etiology and in...
    Speaker: Mark Kennedy, Ph.D. , Richard Josephson, PhD
    Sponsored By: Thermo Fisher Scientific
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