Follow
Drug Development
Drug development: describes the process of developing a new drug that energetically targets a specific weakness in a cell. The process consist of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery.
OCT 29, 2014 | 9:00 AM
Although robust and clinically meaningful biomarkers are key to achieving the current vision for precision (molecularly based), cancer medicine (patient stratification, early diagnosis, drug...
OCT 29, 2014 | 6:00 AM
As next-generation sequencing (NGS) platforms advance in their speed, ease-of-use, and cost-effectiveness, many translational researchers are transitioning from microarrays to RNA sequencing...
OCT 29, 2014 | 6:00 AM
The modern era of Precision Medicine requires targeted delivery of molecular inhibitors that control key processes in disease pathways. PARP (Poly ADP Ribose Polymerase) plays a crucial role...
OCT 28, 2014 | 8:00 AM
The TLA Technology constitutes a paradigm shift in targeted next generation sequencing (NGS). The TLA technology uses the physical proximity of nucleotides within a locus of interest as the b...
SEP 24, 2014 | 3:00 PM
Protein-protein interactions and allosterically regulated enzymes have been challenging but important targets for probe- and drug discovery. We and others have found that fragment-based lead...
SEP 24, 2014 | 2:00 PM
Master regulatory transcription factors localize to the genome in a manner influenced by chromatin accessibility and influencing global chromatin structure. With an interest in understanding...
SEP 24, 2014 | 1:00 PM
This lecture will provide an overview of the Vanderbilt Center for Neuroscience Drug Discovery (VCNDD), focusing on how an Academic Drug Discovery Center was established and is maintained. I...
SEP 24, 2014 | 12:00 PM
In the past decade, we have witnessed an explosion in the availability of high-resolution structural information that sheds light on the binding of diverse classes of ligands to both soluble...
SEP 24, 2014 | 11:45 AM
A panel of veteran biotech reporters will discuss hot topics in drug development. Expect a lively debate on emerging technologies, shifting dynamics on drug pricing, and the general health of...
SEP 24, 2014 | 11:00 AM
This presentation will focus on NuMediis general approach towards the discovery of new therapeutic uses for existing drugs. While the business models for repurposing marketed drugs versus rep...
SEP 24, 2014 | 11:00 AM
Heptares Therapeutics is a structure based drug discovery and development company which uses it StaR technology to enable X-ray structures, fragment screening and other biophysical techniques...
SEP 24, 2014 | 10:00 AM
The ever-quickening pace of breathtaking advances in our understanding of disease biology has implicitly promised a profusion of drugs that will dramatically improve human health and well-bei...
SEP 24, 2014 | 10:00 AM
The ever-quickening pace of breathtaking advances in our understanding of disease biology has implicitly promised a profusion of drugs that will dramatically improve human health and well-bei...
SEP 24, 2014 | 8:00 AM
Target selection is arguably the most important decision in all drug discovery and development activities. No amount of great science can overcome the selection of the wrong target. The rapid...
SEP 24, 2014 | 8:00 AM
Antibiotics are among the most important advances in the history of modern medicine. They turned often acutely fatal infections into treatable indications with radical cures. Antibiotics co...
SEP 24, 2014 | 6:00 AM
Duchenne Muscular Dystrophy (DMD) is an X-linked genetic disease occurring in 1 in 3,500 births, and is uniformly fatal in boys. It is caused by any one of over 50 known mutations in the gen...
SEP 16, 2014 | 9:30 AM
Late-stage drug attrition rates in oncology remain higher than in other therapeutic areas. To reduce attrition, it is critical to identify appropriate drug targets and pre-clinical models. Th...
SEP 16, 2014 | 8:30 AM
The use of biomarkers for the stratification of populations for therapy is a concept that holds the potential to revolutionize clinical trial design, the economics of healthcare, and most imp...
SEP 10, 2014 | 10:00 AM
In this webinar, we will describe a comprehensive approach for NGS-based marker discovery and the successful migration of these markers to targeted NGS assays using low-quality (FFPE) and low...
