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    Epigenetics

    Epigenetics: the study of heritable changes in gene function that do not involve changes in the DNA sequence. Epigenetics often refers to changes in a chromosome that affect gene activity and expression, but can also be used to describe any heritable phenotypic change that does not derive from a modification of the genome, such as prions. Such effects on cellular and physiological phenotypic traits may result from external or environmental factors, or be part of normal developmental program. The standard definition of epigenetics requires these alterations to be heritable, either in the progeny of cells or of organisms.

    Webinars

    • JUN 03, 2020 | 2:00 AM
      A Mitotic Error Code
      A Mitotic Error Code
      Similar to the “histone code” hypothesis in which epigenetic marks on histone tails expand the information potential of the genetic code, different tubulin isoforms, combined wit...
      Speaker: KEYNOTE: Helder Maiato, PhD
      Presented at: Cell & Developmental Biology Virtual Meeting
      3
      MAY 20, 2020 | 12:45 PM
      Molecular and Immunologic Profiling of CD8+ T Cell Responses in Patients Receiving a Multiple Antigen-Engineered Dendritic Cell Vaccine
      Molecular and Immunologic Profiling of CD8+ T Cell Responses in...
      Background: Despite the immunogenicity and safety profile of dendritic cell (DC) vaccines, the importance of vaccine-induced antigen-specific T cell responses is unclear across clinical tria...
      Speaker: Juraj Adamik, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 14, 2020 | 2:15 PM
      First Experience from New World of Easy NGS - Ion Torrent Genexus Workflow
      First Experience from New World of Easy NGS - Ion Torrent Genexus...
      In the past years, next-generation sequencing has revolutionized the way testing is done in the field of clinical oncology research. Parallel testing of genomic markers in tissue biopsies as...
      Speaker: Philip Jermann, PhD
      Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
      8
      MAY 14, 2020 | 2:15 PM
      First Experience from New World of Easy NGS - Ion Torrent Genexus Workflow
      First Experience from New World of Easy NGS - Ion Torrent Genexus...
      In the past years, next-generation sequencing has revolutionized the way testing is done in the field of clinical oncology research. Parallel testing of genomic markers in tissue biopsies as...
      Speaker: Philip Jermann, PhD
      Presented at: OncomineWorld Autumn: A virtual NGS education meeting
      2
      MAY 14, 2020 | 1:25 PM
      Test Validation in Medical Laboratories: the Australian Perspective
      Test Validation in Medical Laboratories: the Australian Perspective
      My laboratory at the Garvan Institute operates an ISO 15189 and NATA accredited laboratory for testing of patients using whole genome and whole exome sequencing, as well as gene panel testin...
      Speaker: Luke Hesson, PhD, FFScRCPA
      Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
      7
      MAY 14, 2020 | 1:25 PM
      NATA Accreditation of Next Generation Sequencing for CDx Testing
      NATA Accreditation of Next Generation Sequencing for CDx Testing
      ...
      Speaker: Luke Hesson, PhD, FFScRCPA
      Presented at: OncomineWorld Autumn: A virtual NGS education meeting
      1
      MAY 14, 2020 | 1:25 PM
      Test Validation in Medical Laboratories: the Australian Perspective
      Test Validation in Medical Laboratories: the Australian Perspective
      My laboratory at the Garvan Institute operates an ISO 15189 and NATA accredited laboratory for testing of patients using whole genome and whole exome sequencing, as well as gene panel testin...
      Speaker: Luke Hesson, PhD, FFScRCPA
      Presented at: OncomineWorld Autumn: A virtual NGS education meeting
      5
      MAY 14, 2020 | 1:25 PM
      NATA Accreditation of Next Generation Sequencing for CDx Testing
      NATA Accreditation of Next Generation Sequencing for CDx Testing
      ...
      Speaker: Luke Hesson, PhD, FFScRCPA
      Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
      6
      MAY 08, 2020 | 10:00 AM
      TCR-seq & BCR-seq Solutions: Applications to Clinical Research Projects
      TCR-seq & BCR-seq Solutions: Applications to Clinical Research...
      DATE: May 8, 2020 TIME: 10:00am PT, 11:00am MT, 1:00pm ET The application of next generation sequencing to interrogate immune repertoires and methods in which these highly complex dataset...
      Speaker: Brian O'Connor, PhD
      Sponsored By: Thermo Fisher Scientific - Ion Torrent
      16 10
      MAY 07, 2020 | 8:00 AM
      When Cell Growth is Critical: Evaluating COâ‚‚ Incubator Parameters for Cell Therapy
      When Cell Growth is Critical: Evaluating COâ‚‚ Incubator Parameters...
      DATE: May 7, 2020 TIME: 8:00AM PDT, 11:00AM EDT With the recent explosion of cell therapy, we know more about conditions affecting cell growth than ever before. Your CO2 incubator should not...
      Speaker: Mary Kay Bates, M.S.
      Sponsored By: Thermo Fisher Scientific
      15 2
      APR 29, 2020 | 6:00 AM
      Parsing Complex Disorders of the Gut-Immune-Brain Axis Into Clinically Meaningful Subsets: Immune Signatures as a Lens for Discovery
      Parsing Complex Disorders of the Gut-Immune-Brain Axis Into Clinically...
      ...
      Speaker: Mady Hornig, MA, MD
      Presented at: xMAP® Connect Virtual Conference (On-Demand)
      2
      APR 29, 2020 | 6:00 AM
      High-Throughput assessment of ChIP-grade capability with Luminex xMAP technology
      High-Throughput assessment of ChIP-grade capability with Luminex...
      Histone post-translational modifications (PTMs) play pivotal roles in chromatin dynamics and function, with alterations in the healthy profile associated with diverse human pathologies. The...
      Speaker: Michael-Christopher Keogh, PhD
      Presented at: xMAP® Connect Virtual Conference (On-Demand)
      1
      APR 24, 2020 | 8:00 AM
      Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide Structural Variant Analysis
      Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide...
      DATE: April 24, 2020 TIME: 8:00am PT, 11:00am ET, 5:00pm CET...
      Speaker: Ben Clifford, PhD , Sven Bocklandt, PhD
      Sponsored By: Bionano
      11
      APR 21, 2020 | 12:00 PM
      Expanding the Hi-C toolbox: New high-resolution approaches for diploid genome phasing, protein-directed chromatin architecture mapping and more
      Expanding the Hi-C toolbox: New high-resolution approaches for...
      Careful and deliberate packaging of the genome is essential to ensuring correct and timely transcriptional programs. Chromatin conformation capture (3C and Hi-C) is a powerful approach for c...
      Speaker: Iain Russell, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      Sponsored By: Dovetail Genomics
      1
      APR 21, 2020 | 12:00 AM
      Contribution of transposons to structural variation and phenotypic diversity in tomato
      Contribution of transposons to structural variation and phenotypic...
      Structural variation within plant genomes has fueled domestication and selection of traits critical for modern breeding of crop plants. Nevertheless, dissecting the diversity of structural v...
      Speaker: Matthias Benoit, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 15, 2020 | 9:00 AM
      Single-cell multi-omics: DNA methylation and 3D genome
      Single-cell multi-omics: DNA methylation and 3D genome
      DATE: April 15, 2020 TIME: 9:00am PT, 12:00pm ET We report a molecular assay, Methyl-HiC, that can simultaneously capture the chromosome conformation and DNA methylome in a cell. Methyl-HiC...
      Speaker: Yaping Liu, Ph.D.
      Sponsored By: Zymo Research
      9 3
      APR 02, 2020 | 8:00 AM
      Bionano Genome Imaging unravels complex structural rearrangements induced by replication stress in liver cancer
      Bionano Genome Imaging unravels complex structural rearrangements...
      DATE: April 2, 2020 TIME: 8:00am PT, 11:00am ET Cyclins A2 and E1 regulate the cell cycle by promoting S phase entry and progression. We recently identified a hepatocellular carcinoma (HCC)...
      Speaker: Eric Letouzé, PhD
      Sponsored By: Bionano
      14
      FEB 26, 2020 | 9:00 AM
      CRISPR Based Screening: Advantages of Transcriptional Activators and Inhibitors
      CRISPR Based Screening: Advantages of Transcriptional Activators...
      CRISPR revolutionized gene editing, but multi-target screening remains a complex goal. In addition, the fast pace of CRISPR technology development has brought sophisticated options for libra...
      Speaker: Andrew Ravanelli, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      2 1
      FEB 25, 2020 | 9:00 AM
      CAR-T Generation for Identity, Purity and Potency Assay Testing
      CAR-T Generation for Identity, Purity and Potency Assay Testing
      Learn about how to generate a small scale CAR-T workflow using ThermoFisher products See detailed characterization tools that can be utilized and applied in a CAR-T workflow...
      Speaker: Tia Hexom, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      10 1
      DEC 04, 2019 | 7:00 AM
      Improve your reproducibility - Liquid Handling is a crucial factor Exemplarily shown for NGS, ELISA and qPCR
      Improve your reproducibility - Liquid Handling is a crucial factor...
      DATE: December 4, 2019TIME: 7:00am PST, 10:00am EST, 4:00pm CET Do you know how it feels when you just quickly want to redo an experiment that your colleague did, or an experim...
      Speaker: Katja Baesler, PhD , Ulrike Gast, PhD , Alisa Gruschka
      Sponsored By: Eppendorf
      12
      NOV 18, 2019 | 7:00 AM
      Protect your cells with proper pipetting - How liquid handling influences your cell culture work
      Protect your cells with proper pipetting - How liquid handling...
      DATE: November 18, 2019TIME: 7:00am PST, 11:00am EST, 4:00pm CEWT How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop th...
      Speaker: Nadine Mellies, PhD , Katja Baesler, PhD
      Sponsored By: Eppendorf
      22 2
      OCT 30, 2019 | 7:00 AM
      A Novel Approach for Single-cell Multi-omic Analysis to Identify Regulatory Signatures in Cancer
      A Novel Approach for Single-cell Multi-omic Analysis to Identify...
      DATE: October 30, 2019TIME: 7:00am PDTJoin us for a webinar to learn how to apply single cell methods to study cancer. Dr. William Greenleaf, Associate Professor from Stanford Universit...
      Speaker: William J. Greenleaf, Ph.D
      Sponsored By: 10x Genomics
      18 1
      SEP 12, 2019 | 10:30 AM
      Analysis of human gut microbiomes and antibiotic resistomes of pediatric patients undergoing stem cell transplantation
      Analysis of human gut microbiomes and antibiotic resistomes of...
      The emergence and spread of antimicrobial-resistant (AMR) bacteria and resistance mechanisms pose a serious challenge to laboratories in both hospital clinical microbiology and public health...
      Speaker: Jonathan Jacobs, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2019
      Sponsored By: QIAGEN
      5
      AUG 13, 2019 | 9:00 AM
      Nanometer-accuracy distance measurements between fluorophores at the single-molecule level
      Nanometer-accuracy distance measurements between fluorophores...
      DATE: August 13, 2019TIME: 9:00am PT, 12:00pm ET, 5:00pm BST Molecular complexes are major constituents of cells, hence unraveling their mechanisms is key to fuller comprehension of c...
      Speaker: Nico Stuurman, PhD , Marcin Barszczewski, PhD
      Sponsored By: Andor
      3
    JUN 03, 2020 | 2:00 AM
    A Mitotic Error Code
    A Mitotic Error Code
    Similar to the “histone code” hypothesis in which epigenetic marks on histone tails expand the information potential of the genetic code, different tubulin isoforms, combined wit...
    Speaker: KEYNOTE: Helder Maiato, PhD
    Presented at: Cell & Developmental Biology Virtual Meeting
    3
    MAY 20, 2020 | 12:45 PM
    Molecular and Immunologic Profiling of CD8+ T Cell Responses in Patients Receiving a Multiple Antigen-Engineered Dendritic Cell Vaccine
    Molecular and Immunologic Profiling of CD8+ T Cell Responses in...
    Background: Despite the immunogenicity and safety profile of dendritic cell (DC) vaccines, the importance of vaccine-induced antigen-specific T cell responses is unclear across clinical tria...
    Speaker: Juraj Adamik, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    MAY 14, 2020 | 2:15 PM
    First Experience from New World of Easy NGS - Ion Torrent Genexus Workflow
    First Experience from New World of Easy NGS - Ion Torrent Genexus...
    In the past years, next-generation sequencing has revolutionized the way testing is done in the field of clinical oncology research. Parallel testing of genomic markers in tissue biopsies as...
    Speaker: Philip Jermann, PhD
    Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
    8
    MAY 14, 2020 | 2:15 PM
    First Experience from New World of Easy NGS - Ion Torrent Genexus Workflow
    First Experience from New World of Easy NGS - Ion Torrent Genexus...
    In the past years, next-generation sequencing has revolutionized the way testing is done in the field of clinical oncology research. Parallel testing of genomic markers in tissue biopsies as...
    Speaker: Philip Jermann, PhD
    Presented at: OncomineWorld Autumn: A virtual NGS education meeting
    2
    MAY 14, 2020 | 1:25 PM
    Test Validation in Medical Laboratories: the Australian Perspective
    Test Validation in Medical Laboratories: the Australian Perspective
    My laboratory at the Garvan Institute operates an ISO 15189 and NATA accredited laboratory for testing of patients using whole genome and whole exome sequencing, as well as gene panel testin...
    Speaker: Luke Hesson, PhD, FFScRCPA
    Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
    7
     
     
  • MAY 14, 2020 | 1:25 PM
    NATA Accreditation of Next Generation Sequencing for CDx Testing
    NATA Accreditation of Next Generation Sequencing for CDx Testing
    ...
    Speaker: Luke Hesson, PhD, FFScRCPA
    Presented at: OncomineWorld Autumn: A virtual NGS education meeting
    1
    MAY 14, 2020 | 1:25 PM
    Test Validation in Medical Laboratories: the Australian Perspective
    Test Validation in Medical Laboratories: the Australian Perspective
    My laboratory at the Garvan Institute operates an ISO 15189 and NATA accredited laboratory for testing of patients using whole genome and whole exome sequencing, as well as gene panel testin...
    Speaker: Luke Hesson, PhD, FFScRCPA
    Presented at: OncomineWorld Autumn: A virtual NGS education meeting
    5
    MAY 14, 2020 | 1:25 PM
    NATA Accreditation of Next Generation Sequencing for CDx Testing
    NATA Accreditation of Next Generation Sequencing for CDx Testing
    ...
    Speaker: Luke Hesson, PhD, FFScRCPA
    Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
    6
    MAY 08, 2020 | 10:00 AM
    TCR-seq & BCR-seq Solutions: Applications to Clinical Research Projects
    TCR-seq & BCR-seq Solutions: Applications to Clinical Research...
    DATE: May 8, 2020 TIME: 10:00am PT, 11:00am MT, 1:00pm ET The application of next generation sequencing to interrogate immune repertoires and methods in which these highly complex dataset...
    Speaker: Brian O'Connor, PhD
    Sponsored By: Thermo Fisher Scientific - Ion Torrent
    16 10
    MAY 07, 2020 | 8:00 AM
    When Cell Growth is Critical: Evaluating COâ‚‚ Incubator Parameters for Cell Therapy
    When Cell Growth is Critical: Evaluating COâ‚‚ Incubator Parameters...
    DATE: May 7, 2020 TIME: 8:00AM PDT, 11:00AM EDT With the recent explosion of cell therapy, we know more about conditions affecting cell growth than ever before. Your CO2 incubator should not...
    Speaker: Mary Kay Bates, M.S.
    Sponsored By: Thermo Fisher Scientific
    15 2
     
     
  • APR 29, 2020 | 6:00 AM
    Parsing Complex Disorders of the Gut-Immune-Brain Axis Into Clinically Meaningful Subsets: Immune Signatures as a Lens for Discovery
    Parsing Complex Disorders of the Gut-Immune-Brain Axis Into Clinically...
    ...
    Speaker: Mady Hornig, MA, MD
    Presented at: xMAP® Connect Virtual Conference (On-Demand)
    2
    APR 29, 2020 | 6:00 AM
    High-Throughput assessment of ChIP-grade capability with Luminex xMAP technology
    High-Throughput assessment of ChIP-grade capability with Luminex...
    Histone post-translational modifications (PTMs) play pivotal roles in chromatin dynamics and function, with alterations in the healthy profile associated with diverse human pathologies. The...
    Speaker: Michael-Christopher Keogh, PhD
    Presented at: xMAP® Connect Virtual Conference (On-Demand)
    1
    APR 24, 2020 | 8:00 AM
    Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide Structural Variant Analysis
    Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide...
    DATE: April 24, 2020 TIME: 8:00am PT, 11:00am ET, 5:00pm CET...
    Speaker: Ben Clifford, PhD , Sven Bocklandt, PhD
    Sponsored By: Bionano
    11
    APR 21, 2020 | 12:00 PM
    Expanding the Hi-C toolbox: New high-resolution approaches for diploid genome phasing, protein-directed chromatin architecture mapping and more
    Expanding the Hi-C toolbox: New high-resolution approaches for...
    Careful and deliberate packaging of the genome is essential to ensuring correct and timely transcriptional programs. Chromatin conformation capture (3C and Hi-C) is a powerful approach for c...
    Speaker: Iain Russell, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    Sponsored By: Dovetail Genomics
    1
    APR 21, 2020 | 12:00 AM
    Contribution of transposons to structural variation and phenotypic diversity in tomato
    Contribution of transposons to structural variation and phenotypic...
    Structural variation within plant genomes has fueled domestication and selection of traits critical for modern breeding of crop plants. Nevertheless, dissecting the diversity of structural v...
    Speaker: Matthias Benoit, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
     
     
  • APR 15, 2020 | 9:00 AM
    Single-cell multi-omics: DNA methylation and 3D genome
    Single-cell multi-omics: DNA methylation and 3D genome
    DATE: April 15, 2020 TIME: 9:00am PT, 12:00pm ET We report a molecular assay, Methyl-HiC, that can simultaneously capture the chromosome conformation and DNA methylome in a cell. Methyl-HiC...
    Speaker: Yaping Liu, Ph.D.
    Sponsored By: Zymo Research
    9 3
    APR 02, 2020 | 8:00 AM
    Bionano Genome Imaging unravels complex structural rearrangements induced by replication stress in liver cancer
    Bionano Genome Imaging unravels complex structural rearrangements...
    DATE: April 2, 2020 TIME: 8:00am PT, 11:00am ET Cyclins A2 and E1 regulate the cell cycle by promoting S phase entry and progression. We recently identified a hepatocellular carcinoma (HCC)...
    Speaker: Eric Letouzé, PhD
    Sponsored By: Bionano
    14
    FEB 26, 2020 | 9:00 AM
    CRISPR Based Screening: Advantages of Transcriptional Activators and Inhibitors
    CRISPR Based Screening: Advantages of Transcriptional Activators...
    CRISPR revolutionized gene editing, but multi-target screening remains a complex goal. In addition, the fast pace of CRISPR technology development has brought sophisticated options for libra...
    Speaker: Andrew Ravanelli, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    2 1
    FEB 25, 2020 | 9:00 AM
    CAR-T Generation for Identity, Purity and Potency Assay Testing
    CAR-T Generation for Identity, Purity and Potency Assay Testing
    Learn about how to generate a small scale CAR-T workflow using ThermoFisher products See detailed characterization tools that can be utilized and applied in a CAR-T workflow...
    Speaker: Tia Hexom, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    10 1
    DEC 04, 2019 | 7:00 AM
    Improve your reproducibility - Liquid Handling is a crucial factor Exemplarily shown for NGS, ELISA and qPCR
    Improve your reproducibility - Liquid Handling is a crucial factor...
    DATE: December 4, 2019TIME: 7:00am PST, 10:00am EST, 4:00pm CET Do you know how it feels when you just quickly want to redo an experiment that your colleague did, or an experim...
    Speaker: Katja Baesler, PhD , Ulrike Gast, PhD , Alisa Gruschka
    Sponsored By: Eppendorf
    12
     
     
  • NOV 18, 2019 | 7:00 AM
    Protect your cells with proper pipetting - How liquid handling influences your cell culture work
    Protect your cells with proper pipetting - How liquid handling...
    DATE: November 18, 2019TIME: 7:00am PST, 11:00am EST, 4:00pm CEWT How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop th...
    Speaker: Nadine Mellies, PhD , Katja Baesler, PhD
    Sponsored By: Eppendorf
    22 2
    OCT 30, 2019 | 7:00 AM
    A Novel Approach for Single-cell Multi-omic Analysis to Identify Regulatory Signatures in Cancer
    A Novel Approach for Single-cell Multi-omic Analysis to Identify...
    DATE: October 30, 2019TIME: 7:00am PDTJoin us for a webinar to learn how to apply single cell methods to study cancer. Dr. William Greenleaf, Associate Professor from Stanford Universit...
    Speaker: William J. Greenleaf, Ph.D
    Sponsored By: 10x Genomics
    18 1
    SEP 12, 2019 | 10:30 AM
    Analysis of human gut microbiomes and antibiotic resistomes of pediatric patients undergoing stem cell transplantation
    Analysis of human gut microbiomes and antibiotic resistomes of...
    The emergence and spread of antimicrobial-resistant (AMR) bacteria and resistance mechanisms pose a serious challenge to laboratories in both hospital clinical microbiology and public health...
    Speaker: Jonathan Jacobs, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2019
    Sponsored By: QIAGEN
    5
    AUG 13, 2019 | 9:00 AM
    Nanometer-accuracy distance measurements between fluorophores at the single-molecule level
    Nanometer-accuracy distance measurements between fluorophores...
    DATE: August 13, 2019TIME: 9:00am PT, 12:00pm ET, 5:00pm BST Molecular complexes are major constituents of cells, hence unraveling their mechanisms is key to fuller comprehension of c...
    Speaker: Nico Stuurman, PhD , Marcin Barszczewski, PhD
    Sponsored By: Andor
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