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    Exosomes

    Exosomes: cell-derived vesicles that are present in many and perhaps all eukaryotic fluids, including blood, urine, and cultured medium of cell cultures. Exosomes are either released from the cell when multivesicular bodies fuse with the plasma membrane or released directly from the plasma membrane. Evidence is accumulating that exosomes have specialized functions and play a key role in processes such as coagulation, intercellular signaling, and waste management.

    Webinars

    • AUG 15, 2018 | 8:00 AM
      3D Spheroid Cell Models for Drug-Resistant Cancer Research
      3D Spheroid Cell Models for Drug-Resistant Cancer Research
      DATE: August 15, 2018TIME: 08:00AM PDT, 11:00AM EDTThe failure of current chemotherapeutic strategies in the fight against cancer can be largely attributed to the occurrence of drug res...
      Speaker: Clarissa Willers, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      9 2
      JUL 19, 2018 | 9:00 AM
      Investigating the role of microRNAs in pancreatic cancer progression
      Investigating the role of microRNAs in pancreatic cancer progression
      DATE:  July 19, 2018TIME:  09:00am PDT Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with a 5 year-survival rate of approximately 6%. Despite recent...
      Speaker: Silvia Ottaviani, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      9 5
      JUN 29, 2018 | 9:00 AM
      Diet and gene interactions in the control of central cell metabolism
      Diet and gene interactions in the control of central cell metabolism
      DATE: June 29, 2018TIME: 09:00AM PDT, 12:00PM EDT There is significant epidemiological evidence to suggest that the consumption of a high-broccoli diet is associated with a r...
      Speaker: Sophie Prosolek
      Sponsored By: Thermo Fisher Scientific/Gibco
      6 2
      MAY 24, 2018 | 9:30 AM
      Turning to a new dimension in cell culture for cancer research
      Turning to a new dimension in cell culture for cancer research
      DATE: May 24, 2018 TIME: 9:30PM PDT The current gold standard in in vitro pre-clinical cancer treatment screening remain cell lines,...
      Speaker: Carlemi Calitz, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      14 2
      MAY 09, 2018 | 1:30 PM
      Next-Generation Sequencing to Understand the Function of miRNAs in Human IPSC-Cardiomyocyte Disease Models
      Next-Generation Sequencing to Understand the Function of miRNAs...
      There is increasing evidence that intracellular miRNAs play a role in the pathogenesis of many complex disease phenotypes.  In addition, extracellular miRNAs in exosomes are emerging as...
      Speaker: Ulrich Broeckel, MD , Amy Turner, BS
      Presented at: Genetics and Genomics Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      MAY 09, 2018 | 10:30 AM
      The microRNA Regulatory Landscape of MSC-Derived Exosomes: A Systems View
      The microRNA Regulatory Landscape of MSC-Derived Exosomes: A Systems...
      Mesenchymal stem cell (MSC)-derived exosomes mediate tissue regeneration in a variety of diseases including ischemic heart injury, liver fibrosis, and cerebrovascular disease. Despite an incr...
      Speaker: Juliane Nguyen, PharmD, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2018
      Sponsored By: NanoString Technologies
      3
      APR 27, 2018 | 10:00 AM
      Investigating DNA repair mechanisms in hypoxic brain tumours and the link to treatment resistance
      Investigating DNA repair mechanisms in hypoxic brain tumours and...
      DATE: April 27, 2018TIME: 10:00am PST, 1:00pm ESTGlioblastoma (GBM) and Medulloblastoma (MB) are the most common adult and paediatric brain tumours, both of which can have devastating c...
      Speaker: Sophie Cowman
      Sponsored By: Thermo Fisher Scientific/Gibco
      10 4
      MAR 22, 2018 | 9:00 AM
      Differentiation sensitizes stem-like glioblastoma tumor-initiating cells to mechanical inputs
      Differentiation sensitizes stem-like glioblastoma tumor-initiating...
      DATE: March 22, 2018TIME: 09:00am PST, 12:00pm ESTGlioblastoma (GBM) is the most aggressive primary brain cancer, with nearly universal recurrence after treatment. GBMs are highly heter...
      Speaker: Jasmine Hughes
      Sponsored By: Thermo Fisher Scientific/Gibco
      6 4
      NOV 14, 2017 | 12:00 PM
      WEBINAR: Exosome miRNA sequencing for biomarker profiling using the Ion S5 System and Ion Total RNA-seq kit
      WEBINAR: Exosome miRNA sequencing for biomarker profiling using...
      DATE: November 14, 2017TIME: 12:00pm PST, 03:00pm ESTLearning Objectives: How to maximise RNA yield and extraction from exosomes and biological fluids How to construct small RNA...
      Speaker: Dr. Lesley Cheng
      Sponsored By: Thermo Fisher Scientific - Ion Torrent
      9
      OCT 12, 2017 | 10:30 AM
      Hypersecretion of fibroblast-derived exosomes during chemotherapy promotes pancreatic cancer chemoresistance
      Hypersecretion of fibroblast-derived exosomes during chemotherapy...
      Pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of only 9%. Acquired drug resistance is a major factor that limits the effectiveness of chemotherapy. Exosomes, secreted...
      Speaker: Reginald Hill, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
      1
      OCT 11, 2017 | 10:30 AM
      Brain Tumor Exosomes in Cancer Immunity: Fat Balls of Immune Confusion
      Brain Tumor Exosomes in Cancer Immunity: Fat Balls of Immune Confusion
      Exosomes are nano-scale lipid membrane-enclosed extracellular vesicles that form in the cellular endosomal system but are released outside the cell. These virus-sized “fat balls”...
      Speaker: Michael Graner, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
      1
      SEP 28, 2017 | 1:30 PM
      The RRID Initiative, what is needed for scholarship in the 21st century
      The RRID Initiative, what is needed for scholarship in the 21st...
      The Resource Identification Initiative supports NIH's new guidelines for Rigor and Transparency as these apply in biomedical publications. Authors are instructed to authenticate key biolo...
      Speaker: Anita Bandrowski, PhD
      Presented at: Cell Biology Virtual Event Series 2017
      1
      SEP 28, 2017 | 12:00 PM
      Back to basics: Fundamental concepts and special considerations in RNA isolation
      Back to basics: Fundamental concepts and special considerations...
      How are your RNA yields? Some sample types present special challenges in RNA purification and analysis. In this webinar, we will discuss and provide tips for the following topics: &b...
      Speaker: Abhishek Sharma
      Presented at: Cell Biology Virtual Event Series 2017
      2
      SEP 28, 2017 | 10:30 AM
      Engineering stem cell biology for disease modelling and therapeutics
      Engineering stem cell biology for disease modelling and therapeutics
      Stem cells can self-renew and differentiate into multiple different cell types. Engineering of stem cells has enabled new methods to study development and organogenesis in humans as well as d...
      Speaker: Amr Abdeen, PhD
      Presented at: Cell Biology Virtual Event Series 2017
      1
      SEP 28, 2017 | 9:00 AM
      Fine tuning of myosin activity shapes actomyosin network organization and tissue contractility of the C. elegans spermatheca
      Fine tuning of myosin activity shapes actomyosin network organization...
      Contractile non-muscle cells, including smooth muscle and myoepithelial cells, provide the mechanical forces required for tissue homeostasis in numerous organ systems. For example, smooth mus...
      Speaker: Alison Wirshing, PhD
      Presented at: Cell Biology Virtual Event Series 2017
      1
      SEP 28, 2017 | 7:30 AM
      Keynote Presentation: RNA-targeting CRISPR and application to diseases
      Keynote Presentation: RNA-targeting CRISPR and application to...
      I will present my lab’s effort on studying and manipulating RNA processing, with particular emphasis on using CRISPR/Cas systems for targeting RNA in living cells in diseases such as my...
      Speaker: Gene Yeo, PhD
      Presented at: Cell Biology Virtual Event Series 2017
      1
      SEP 28, 2017 | 6:00 AM
      The axolotl salamander as a model for nerve-dependent regeneration
      The axolotl salamander as a model for nerve-dependent regeneration
      The Mexican axolotl (Ambystoma mexicanum) is an aquatic salamander that possesses some of the most astonishing regenerative abilities found in nature.  Able to fully regenerate amputated...
      Speaker: Johanna Farkas, PhD
      Presented at: Cell Biology Virtual Event Series 2017
      1
      SEP 27, 2017 | 1:30 PM
      Evolutionary Cell Biology is a powerful paradigm to study complex biological systems
      Evolutionary Cell Biology is a powerful paradigm to study complex...
      Although the cell is commonly referred to as “the most basic unit of life”, it is actually so complex that despite over 350 years of research we are still far from fully understan...
      Speaker: Idan Frumkin, PhD
      Presented at: Cell Biology Virtual Event Series 2017
      1
      SEP 27, 2017 | 12:00 PM
      CRISPR-Cas9 genome engineering: Experimental Design and Applications
      CRISPR-Cas9 genome engineering: Experimental Design and Applications
      The manipulation of the genome to study disease, evaluate drug targets and to stratify patient populations is now a widely accepted concept in the field. At Horizon Discovery, genome engineer...
      Speaker: Danielle Folkard
      Presented at: Cell Biology Virtual Event Series 2017
      Sponsored By: Horizon Discovery
      2
      SEP 27, 2017 | 9:00 AM
      Regulation of actin during cell migration by nucleotide coding sequence and arginylation
      Regulation of actin during cell migration by nucleotide coding...
      Actin cytoskeleton drives cell migration in muscle and non-muscle cells and plays a major role in such diverse processes as tissue morphogenesis, muscle contraction, and cancer metastases. In...
      Speaker: Anna Kashina, PhD
      Presented at: Cell Biology Virtual Event Series 2017
      1
      SEP 27, 2017 | 7:30 AM
      Keynote Presentation: What Microscopy Can Tell Us About the Life of an mRNA in Living Cells
      Keynote Presentation: What Microscopy Can Tell Us About the Life...
      Einstein researcher Robert Singer, Ph.D., discusses a breakthrough in microscopy that is allowing scientists to track messenger RNA in living cells in real time. The study, published in the S...
      Speaker: Robert Singer, PhD
      Presented at: Cell Biology Virtual Event Series 2017
      1
      SEP 27, 2017 | 6:00 AM
      Regulation of microtubule plus-end dynamics during axon guidance and cell migration
      Regulation of microtubule plus-end dynamics during axon guidance...
      A fundamental question in neuronal development is how growth cone cytoskeletal dynamics are coordinated to promote accurate axonal navigation. To address this question, we focus on microtubul...
      Speaker: Laura Lowery, PhD
      Presented at: Cell Biology Virtual Event Series 2017
      1
      SEP 06, 2017 | 9:00 AM
      WEBINAR: Manufacturing and characterization of therapeutic exosomes for clinical studies
      WEBINAR: Manufacturing and characterization of therapeutic exosomes...
      DATE: September 6, 2017TIME: 9:00AM PST, 12:00PM ET The era of using extracellular vesicles (EVs) and exosomes for regenerative medicine applications in the clinic is here. We...
      Speaker: Travis Antes, PhD
      Sponsored By: Miltenyi Biotec
      9
      JAN 17, 2017 | 8:00 AM
      Benefits and limitations of primary and secondary antibody conjugates
      Benefits and limitations of primary and secondary antibody conjugates
      Join Dr Javier Conde Vancells as he reviews the use of primary and secondary antibody conjugates across multiple lab applications, including a review of direct vs. indirect methods in cellula...
      Speaker: Javier Vancells, PhD
      Presented at: Abcam virtual exhibition: support and products to advance your research
      4
    AUG 15, 2018 | 8:00 AM
    3D Spheroid Cell Models for Drug-Resistant Cancer Research
    3D Spheroid Cell Models for Drug-Resistant Cancer Research
    DATE: August 15, 2018TIME: 08:00AM PDT, 11:00AM EDTThe failure of current chemotherapeutic strategies in the fight against cancer can be largely attributed to the occurrence of drug res...
    Speaker: Clarissa Willers, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    9 2
    JUL 19, 2018 | 9:00 AM
    Investigating the role of microRNAs in pancreatic cancer progression
    Investigating the role of microRNAs in pancreatic cancer progression
    DATE:  July 19, 2018TIME:  09:00am PDT Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with a 5 year-survival rate of approximately 6%. Despite recent...
    Speaker: Silvia Ottaviani, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    9 5
    JUN 29, 2018 | 9:00 AM
    Diet and gene interactions in the control of central cell metabolism
    Diet and gene interactions in the control of central cell metabolism
    DATE: June 29, 2018TIME: 09:00AM PDT, 12:00PM EDT There is significant epidemiological evidence to suggest that the consumption of a high-broccoli diet is associated with a r...
    Speaker: Sophie Prosolek
    Sponsored By: Thermo Fisher Scientific/Gibco
    6 2
    MAY 24, 2018 | 9:30 AM
    Turning to a new dimension in cell culture for cancer research
    Turning to a new dimension in cell culture for cancer research
    DATE: May 24, 2018 TIME: 9:30PM PDT The current gold standard in in vitro pre-clinical cancer treatment screening remain cell lines,...
    Speaker: Carlemi Calitz, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    14 2
    MAY 09, 2018 | 1:30 PM
    Next-Generation Sequencing to Understand the Function of miRNAs in Human IPSC-Cardiomyocyte Disease Models
    Next-Generation Sequencing to Understand the Function of miRNAs...
    There is increasing evidence that intracellular miRNAs play a role in the pathogenesis of many complex disease phenotypes.  In addition, extracellular miRNAs in exosomes are emerging as...
    Speaker: Ulrich Broeckel, MD , Amy Turner, BS
    Presented at: Genetics and Genomics Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
     
     
  • MAY 09, 2018 | 10:30 AM
    The microRNA Regulatory Landscape of MSC-Derived Exosomes: A Systems View
    The microRNA Regulatory Landscape of MSC-Derived Exosomes: A Systems...
    Mesenchymal stem cell (MSC)-derived exosomes mediate tissue regeneration in a variety of diseases including ischemic heart injury, liver fibrosis, and cerebrovascular disease. Despite an incr...
    Speaker: Juliane Nguyen, PharmD, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2018
    Sponsored By: NanoString Technologies
    3
    APR 27, 2018 | 10:00 AM
    Investigating DNA repair mechanisms in hypoxic brain tumours and the link to treatment resistance
    Investigating DNA repair mechanisms in hypoxic brain tumours and...
    DATE: April 27, 2018TIME: 10:00am PST, 1:00pm ESTGlioblastoma (GBM) and Medulloblastoma (MB) are the most common adult and paediatric brain tumours, both of which can have devastating c...
    Speaker: Sophie Cowman
    Sponsored By: Thermo Fisher Scientific/Gibco
    10 4
    MAR 22, 2018 | 9:00 AM
    Differentiation sensitizes stem-like glioblastoma tumor-initiating cells to mechanical inputs
    Differentiation sensitizes stem-like glioblastoma tumor-initiating...
    DATE: March 22, 2018TIME: 09:00am PST, 12:00pm ESTGlioblastoma (GBM) is the most aggressive primary brain cancer, with nearly universal recurrence after treatment. GBMs are highly heter...
    Speaker: Jasmine Hughes
    Sponsored By: Thermo Fisher Scientific/Gibco
    6 4
    NOV 14, 2017 | 12:00 PM
    WEBINAR: Exosome miRNA sequencing for biomarker profiling using the Ion S5 System and Ion Total RNA-seq kit
    WEBINAR: Exosome miRNA sequencing for biomarker profiling using...
    DATE: November 14, 2017TIME: 12:00pm PST, 03:00pm ESTLearning Objectives: How to maximise RNA yield and extraction from exosomes and biological fluids How to construct small RNA...
    Speaker: Dr. Lesley Cheng
    Sponsored By: Thermo Fisher Scientific - Ion Torrent
    9
    OCT 12, 2017 | 10:30 AM
    Hypersecretion of fibroblast-derived exosomes during chemotherapy promotes pancreatic cancer chemoresistance
    Hypersecretion of fibroblast-derived exosomes during chemotherapy...
    Pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of only 9%. Acquired drug resistance is a major factor that limits the effectiveness of chemotherapy. Exosomes, secreted...
    Speaker: Reginald Hill, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
    1
     
     
  • OCT 11, 2017 | 10:30 AM
    Brain Tumor Exosomes in Cancer Immunity: Fat Balls of Immune Confusion
    Brain Tumor Exosomes in Cancer Immunity: Fat Balls of Immune Confusion
    Exosomes are nano-scale lipid membrane-enclosed extracellular vesicles that form in the cellular endosomal system but are released outside the cell. These virus-sized “fat balls”...
    Speaker: Michael Graner, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
    1
    SEP 28, 2017 | 1:30 PM
    The RRID Initiative, what is needed for scholarship in the 21st century
    The RRID Initiative, what is needed for scholarship in the 21st...
    The Resource Identification Initiative supports NIH's new guidelines for Rigor and Transparency as these apply in biomedical publications. Authors are instructed to authenticate key biolo...
    Speaker: Anita Bandrowski, PhD
    Presented at: Cell Biology Virtual Event Series 2017
    1
    SEP 28, 2017 | 12:00 PM
    Back to basics: Fundamental concepts and special considerations in RNA isolation
    Back to basics: Fundamental concepts and special considerations...
    How are your RNA yields? Some sample types present special challenges in RNA purification and analysis. In this webinar, we will discuss and provide tips for the following topics: &b...
    Speaker: Abhishek Sharma
    Presented at: Cell Biology Virtual Event Series 2017
    2
    SEP 28, 2017 | 10:30 AM
    Engineering stem cell biology for disease modelling and therapeutics
    Engineering stem cell biology for disease modelling and therapeutics
    Stem cells can self-renew and differentiate into multiple different cell types. Engineering of stem cells has enabled new methods to study development and organogenesis in humans as well as d...
    Speaker: Amr Abdeen, PhD
    Presented at: Cell Biology Virtual Event Series 2017
    1
    SEP 28, 2017 | 9:00 AM
    Fine tuning of myosin activity shapes actomyosin network organization and tissue contractility of the C. elegans spermatheca
    Fine tuning of myosin activity shapes actomyosin network organization...
    Contractile non-muscle cells, including smooth muscle and myoepithelial cells, provide the mechanical forces required for tissue homeostasis in numerous organ systems. For example, smooth mus...
    Speaker: Alison Wirshing, PhD
    Presented at: Cell Biology Virtual Event Series 2017
    1
     
     
  • SEP 28, 2017 | 7:30 AM
    Keynote Presentation: RNA-targeting CRISPR and application to diseases
    Keynote Presentation: RNA-targeting CRISPR and application to...
    I will present my lab’s effort on studying and manipulating RNA processing, with particular emphasis on using CRISPR/Cas systems for targeting RNA in living cells in diseases such as my...
    Speaker: Gene Yeo, PhD
    Presented at: Cell Biology Virtual Event Series 2017
    1
    SEP 28, 2017 | 6:00 AM
    The axolotl salamander as a model for nerve-dependent regeneration
    The axolotl salamander as a model for nerve-dependent regeneration
    The Mexican axolotl (Ambystoma mexicanum) is an aquatic salamander that possesses some of the most astonishing regenerative abilities found in nature.  Able to fully regenerate amputated...
    Speaker: Johanna Farkas, PhD
    Presented at: Cell Biology Virtual Event Series 2017
    1
    SEP 27, 2017 | 1:30 PM
    Evolutionary Cell Biology is a powerful paradigm to study complex biological systems
    Evolutionary Cell Biology is a powerful paradigm to study complex...
    Although the cell is commonly referred to as “the most basic unit of life”, it is actually so complex that despite over 350 years of research we are still far from fully understan...
    Speaker: Idan Frumkin, PhD
    Presented at: Cell Biology Virtual Event Series 2017
    1
    SEP 27, 2017 | 12:00 PM
    CRISPR-Cas9 genome engineering: Experimental Design and Applications
    CRISPR-Cas9 genome engineering: Experimental Design and Applications
    The manipulation of the genome to study disease, evaluate drug targets and to stratify patient populations is now a widely accepted concept in the field. At Horizon Discovery, genome engineer...
    Speaker: Danielle Folkard
    Presented at: Cell Biology Virtual Event Series 2017
    Sponsored By: Horizon Discovery
    2
    SEP 27, 2017 | 9:00 AM
    Regulation of actin during cell migration by nucleotide coding sequence and arginylation
    Regulation of actin during cell migration by nucleotide coding...
    Actin cytoskeleton drives cell migration in muscle and non-muscle cells and plays a major role in such diverse processes as tissue morphogenesis, muscle contraction, and cancer metastases. In...
    Speaker: Anna Kashina, PhD
    Presented at: Cell Biology Virtual Event Series 2017
    1
     
     
  • SEP 27, 2017 | 7:30 AM
    Keynote Presentation: What Microscopy Can Tell Us About the Life of an mRNA in Living Cells
    Keynote Presentation: What Microscopy Can Tell Us About the Life...
    Einstein researcher Robert Singer, Ph.D., discusses a breakthrough in microscopy that is allowing scientists to track messenger RNA in living cells in real time. The study, published in the S...
    Speaker: Robert Singer, PhD
    Presented at: Cell Biology Virtual Event Series 2017
    1
    SEP 27, 2017 | 6:00 AM
    Regulation of microtubule plus-end dynamics during axon guidance and cell migration
    Regulation of microtubule plus-end dynamics during axon guidance...
    A fundamental question in neuronal development is how growth cone cytoskeletal dynamics are coordinated to promote accurate axonal navigation. To address this question, we focus on microtubul...
    Speaker: Laura Lowery, PhD
    Presented at: Cell Biology Virtual Event Series 2017
    1
    SEP 06, 2017 | 9:00 AM
    WEBINAR: Manufacturing and characterization of therapeutic exosomes for clinical studies
    WEBINAR: Manufacturing and characterization of therapeutic exosomes...
    DATE: September 6, 2017TIME: 9:00AM PST, 12:00PM ET The era of using extracellular vesicles (EVs) and exosomes for regenerative medicine applications in the clinic is here. We...
    Speaker: Travis Antes, PhD
    Sponsored By: Miltenyi Biotec
    9
    JAN 17, 2017 | 8:00 AM
    Benefits and limitations of primary and secondary antibody conjugates
    Benefits and limitations of primary and secondary antibody conjugates
    Join Dr Javier Conde Vancells as he reviews the use of primary and secondary antibody conjugates across multiple lab applications, including a review of direct vs. indirect methods in cellula...
    Speaker: Javier Vancells, PhD
    Presented at: Abcam virtual exhibition: support and products to advance your research
    4
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