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    Gene Silencing

    Gene Silencing: describes the epigenetic regulation of a gene, at the level of transcription or translation, to prevent gene expression. Mechanisms include DNA methylation, histone modification and RNAi. Methods to silence genes are exploited by researchers to study gene function, and for the development of therapeutics for diseases including cancer, infectious diseases and neurodegenerative disorders.

    Trending News

    • APR 24, 2018
      Cancer
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      Synthetic Retinoid Shows Promise for Inhibition of Cancer Cells
      Researchers studied the potential use of a synthetic retinoid, WYC-209, as an inhibitor of cancer cell growth and metast ...
      Written By: Mauri Brueggeman
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      APR 03, 2018
      Genetics & Genomics
      Beneficial Genetic Mutations Could Help Patients
      Beneficial Genetic Mutations Could Help Patients
      New research findings could help develop treatments for a variety of blood disorders, like sickle cell anemia.
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      FEB 16, 2018
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      Clinical Trial for Cannabidiol Effect on Hyperphagia in Affected Individuals with Prader-Willi Syndrome
      Clinical trial starting March 2018 to examine the effect of cannabidiol on hyperphasia in individuals with Prader-Willi ...
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      JAN 31, 2018
      Clinical & Molecular DX
      Scientists Diagnose Rare Condition Affecting Vitamin B12 Processing
      Scientists Diagnose Rare Condition Affecting Vitamin B12 Processing
      A new discovery is making scientists rethink everything they know about rare hereditary diseases. One genetic mechanism ...
      Written By: Kara Marker
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      JAN 09, 2018
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      Protecting Against Glioblastoma
      Protecting Against Glioblastoma
      Researchers at the Spanish National Cancer Research Centre (CNIO) have made progress in the fight against glioblastoma.
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      4
      DEC 19, 2017
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      'Junk' Gene Implicated in Cancer's Growth
      'Junk' Gene Implicated in Cancer's Growth
      One of the biggest surprise findings from the completion of the Human Genome Project was that only 1.5 percent of our ge ...
      Written By: Xuan Pham
      2
      DEC 17, 2017
      Drug Discovery & Development
      Epigenetic Drugs: Promising Therapeutics
      Epigenetic Drugs: Promising Therapeutics
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      Written By: Courtney Schaal
      2
      DEC 07, 2017
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      Using CRISPR For Epigenetic Modifications
      Using CRISPR For Epigenetic Modifications
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      2
      NOV 13, 2017
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      Natural Killer Cells Target Cancer, Shrink Tumors
      Natural Killer Cells Target Cancer, Shrink Tumors
      The battle between the immune system and growing tumors involves natural killer (NK) cells and a protective barrier put ...
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      3
      SEP 26, 2017
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      New Advances In Treatment of Aggressive Brain Tumors
      Brain cancer, in all of its forms, is a highly aggressive form of the disease, that has proven difficult to access and t ...
      Written By: Brenda Kelley Kim
      2
      AUG 21, 2017
      Cell & Molecular Biology
      Faulty Genetic Replication can Cause Problems for Future Generations
      Faulty Genetic Replication can Cause Problems for Future Generations
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      Written By: Carmen Leitch
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      AUG 11, 2017
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      JUL 11, 2017
      Cell & Molecular Biology
      Treatment for Mitochondrial Disease in Development
      Treatment for Mitochondrial Disease in Development
      Mitochondria carry a small amount of their own DNA. If there are mutations in that DNA, they can cause serious disease.
      Written By: Carmen Leitch
      2
      JUN 08, 2017
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      Predicting Huntington's Disease From Blood
      Predicting Huntington's Disease From Blood
      Researchers from the University College London announced the first blood biomarker that can predict and track the progre ...
      Written By: Xuan Pham
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      JUN 04, 2017
      Cell & Molecular Biology
      Sour Taste Cells Also Sense Water
      Sour Taste Cells Also Sense Water
      Reearchers have found that taste cells that detect sour flavors also appear to react to water.
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      JUN 01, 2017
      Cancer
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      MAY 26, 2017
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      Cotton pest has a sweet tooth
      Cotton pest has a sweet tooth
      Xanthomonas citri subsp. Malvacearum (Xcm) causes bacterial blight in cotton. The disease was rampant in the US during t ...
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      MAY 05, 2017
      Clinical & Molecular DX
      'Exercise-in-a-pill' boosts stamina in mice
      'Exercise-in-a-pill' boosts stamina in mice
      Is it possible to bypass countless hours of endurance training by popping a stamina pill? Recent research in mouse studi ...
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      3
      APR 15, 2017
      Cancer
      Study IDs MicroRNA as a New Target for Pancreatic Cancer
      Study IDs MicroRNA as a New Target for Pancreatic Cancer
      Tiny non-coding RNA molecules may have a role in the progression of pancreatic cancer, one of the most aggressive diseas ...
      Written By: Xuan Pham
      4 1
      MAR 13, 2017
      Cell & Molecular Biology
      Transgenic Engineering Takes Dangerous Toxin Out of Corn
      Transgenic Engineering Takes Dangerous Toxin Out of Corn
      While there is a lot of skepticism surrounding genetically modified foods, they have helped solve serious problems in ag ...
      Written By: Carmen Leitch
      3
      MAR 12, 2017
      Clinical & Molecular DX
      Protein Linked to Fragile X and Autism is a Treatment Target
      Protein Linked to Fragile X and Autism is a Treatment Target
      There is a lack of reliable treatment options for autism, due in part to a poor understanding of how the disease works o ...
      Written By: Carmen Leitch
      2
      MAR 08, 2017
      Cancer
      DNA Enhancer Elements Promote Colorectal Cancer
      DNA Enhancer Elements Promote Colorectal Cancer
      Colon and rectal cancer rate are on the rise, especially in the young, as outlined in the following video. Scientists do ...
      Written By: Carmen Leitch
      2
      JAN 30, 2017
      Neuroscience
      New TSRI Study Shows Early Brain Changes in Fragile X Syndrome
      New TSRI Study Shows Early Brain Changes in Fragile X Syndrome
      Image Credit: PeteLinforth/Pixabay LA JOLLA, CA – January 30, 2017 – A new study led by scientists at The Sc ...
      Written By: The Scripps Research Institute (TSRI)
      4
      JAN 28, 2017
      Cell & Molecular Biology
      Chimera Advancements Boost Biomedical Therapy & Research
      Chimera Advancements Boost Biomedical Therapy & Research
      Chimeras have cells from two different organisms growing in the same animal. You might see some wild headlines about the ...
      Written By: Carmen Leitch
      2
    APR 24, 2018
    Cancer
    Synthetic Retinoid Shows Promise for Inhibition of Cancer Cells
    Synthetic Retinoid Shows Promise for Inhibition of Cancer Cells
    Researchers studied the potential use of a synthetic retinoid, WYC-209, as an inhibitor of cancer cell growth and metast ...
    Written By: Mauri Brueggeman
    2
    APR 03, 2018
    Genetics & Genomics
    Beneficial Genetic Mutations Could Help Patients
    Beneficial Genetic Mutations Could Help Patients
    New research findings could help develop treatments for a variety of blood disorders, like sickle cell anemia.
    Written By: Carmen Leitch
    2
    FEB 16, 2018
    Cannabis Sciences
    Clinical Trial for Cannabidiol Effect on Hyperphagia in Affected Individuals with Prader-Willi Syndrome
    Clinical Trial for Cannabidiol Effect on Hyperphagia in Affected Individuals with Prader-Willi Syndrome
    Clinical trial starting March 2018 to examine the effect of cannabidiol on hyperphasia in individuals with Prader-Willi ...
    Written By: Mauri Brueggeman
    2
    JAN 31, 2018
    Clinical & Molecular DX
    Scientists Diagnose Rare Condition Affecting Vitamin B12 Processing
    Scientists Diagnose Rare Condition Affecting Vitamin B12 Processing
    A new discovery is making scientists rethink everything they know about rare hereditary diseases. One genetic mechanism ...
    Written By: Kara Marker
    3
    JAN 09, 2018
    Cell & Molecular Biology
    Protecting Against Glioblastoma
    Protecting Against Glioblastoma
    Researchers at the Spanish National Cancer Research Centre (CNIO) have made progress in the fight against glioblastoma.
    Written By: Carmen Leitch
    4
     
     
  • DEC 19, 2017
    Cancer
    'Junk' Gene Implicated in Cancer's Growth
    'Junk' Gene Implicated in Cancer's Growth
    One of the biggest surprise findings from the completion of the Human Genome Project was that only 1.5 percent of our ge ...
    Written By: Xuan Pham
    2
    DEC 17, 2017
    Drug Discovery & Development
    Epigenetic Drugs: Promising Therapeutics
    Epigenetic Drugs: Promising Therapeutics
    Brief overview of epigenetic therapeutics
    Written By: Courtney Schaal
    2
    DEC 07, 2017
    Genetics & Genomics
    Using CRISPR For Epigenetic Modifications
    Using CRISPR For Epigenetic Modifications
    CRISPR/Cas9 gene editing technology has been hailed as revolutionary, but the technique came with some caveats. Now, it ...
    Written By: Carmen Leitch
    2
    NOV 13, 2017
    Immunology
    Natural Killer Cells Target Cancer, Shrink Tumors
    Natural Killer Cells Target Cancer, Shrink Tumors
    The battle between the immune system and growing tumors involves natural killer (NK) cells and a protective barrier put ...
    Written By: Kara Marker
    3
    SEP 26, 2017
    Neuroscience
    New Advances In Treatment of Aggressive Brain Tumors
    New Advances In Treatment of Aggressive Brain Tumors
    Brain cancer, in all of its forms, is a highly aggressive form of the disease, that has proven difficult to access and t ...
    Written By: Brenda Kelley Kim
    2
     
     
  • AUG 21, 2017
    Cell & Molecular Biology
    Faulty Genetic Replication can Cause Problems for Future Generations
    Faulty Genetic Replication can Cause Problems for Future Generations
    Our genomic material is in a constant state of replication, and errors in that process have been linked to disease. New ...
    Written By: Carmen Leitch
    1
    AUG 11, 2017
    Cell & Molecular Biology
    Retrovirus-free Piglets may Help Bring Transplant Organs to Patients
    Retrovirus-free Piglets may Help Bring Transplant Organs to Patients
    One way to help the many people that wait on transplant lists for an available organ would be to grow new ones. New work ...
    Written By: Carmen Leitch
    1 1
    JUL 11, 2017
    Cell & Molecular Biology
    Treatment for Mitochondrial Disease in Development
    Treatment for Mitochondrial Disease in Development
    Mitochondria carry a small amount of their own DNA. If there are mutations in that DNA, they can cause serious disease.
    Written By: Carmen Leitch
    2
    JUN 08, 2017
    Clinical & Molecular DX
    Predicting Huntington's Disease From Blood
    Predicting Huntington's Disease From Blood
    Researchers from the University College London announced the first blood biomarker that can predict and track the progre ...
    Written By: Xuan Pham
    3
    JUN 04, 2017
    Cell & Molecular Biology
    Sour Taste Cells Also Sense Water
    Sour Taste Cells Also Sense Water
    Reearchers have found that taste cells that detect sour flavors also appear to react to water.
    Written By: Carmen Leitch
    1 1
     
     
  • JUN 01, 2017
    Cancer
    Drinking Tea Alters Women's Epigenetics
    Drinking Tea Alters Women's Epigenetics
    A hot cup of tea can do wonders to soothe and calm. But this popular beverage could be altering the body’s epigene ...
    Written By: Xuan Pham
    3
    MAY 26, 2017
    Microbiology
    Cotton pest has a sweet tooth
    Cotton pest has a sweet tooth
    Xanthomonas citri subsp. Malvacearum (Xcm) causes bacterial blight in cotton. The disease was rampant in the US during t ...
    Written By: Kerry Evans
    2
    MAY 05, 2017
    Clinical & Molecular DX
    'Exercise-in-a-pill' boosts stamina in mice
    'Exercise-in-a-pill' boosts stamina in mice
    Is it possible to bypass countless hours of endurance training by popping a stamina pill? Recent research in mouse studi ...
    Written By: Xuan Pham
    3
    APR 15, 2017
    Cancer
    Study IDs MicroRNA as a New Target for Pancreatic Cancer
    Study IDs MicroRNA as a New Target for Pancreatic Cancer
    Tiny non-coding RNA molecules may have a role in the progression of pancreatic cancer, one of the most aggressive diseas ...
    Written By: Xuan Pham
    4 1
    MAR 13, 2017
    Cell & Molecular Biology
    Transgenic Engineering Takes Dangerous Toxin Out of Corn
    Transgenic Engineering Takes Dangerous Toxin Out of Corn
    While there is a lot of skepticism surrounding genetically modified foods, they have helped solve serious problems in ag ...
    Written By: Carmen Leitch
    3
     
     
  • MAR 12, 2017
    Clinical & Molecular DX
    Protein Linked to Fragile X and Autism is a Treatment Target
    Protein Linked to Fragile X and Autism is a Treatment Target
    There is a lack of reliable treatment options for autism, due in part to a poor understanding of how the disease works o ...
    Written By: Carmen Leitch
    2
    MAR 08, 2017
    Cancer
    DNA Enhancer Elements Promote Colorectal Cancer
    DNA Enhancer Elements Promote Colorectal Cancer
    Colon and rectal cancer rate are on the rise, especially in the young, as outlined in the following video. Scientists do ...
    Written By: Carmen Leitch
    2
    JAN 30, 2017
    Neuroscience
    New TSRI Study Shows Early Brain Changes in Fragile X Syndrome
    New TSRI Study Shows Early Brain Changes in Fragile X Syndrome
    Image Credit: PeteLinforth/Pixabay LA JOLLA, CA – January 30, 2017 – A new study led by scientists at The Sc ...
    Written By: The Scripps Research Institute (TSRI)
    4
    JAN 28, 2017
    Cell & Molecular Biology
    Chimera Advancements Boost Biomedical Therapy & Research
    Chimera Advancements Boost Biomedical Therapy & Research
    Chimeras have cells from two different organisms growing in the same animal. You might see some wild headlines about the ...
    Written By: Carmen Leitch
    2
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