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    Gene Therapy

    Gene Therapy: Gene therapy is designed to introduce genetic material into cells to compensate for abnormal genes or to make a beneficial protein. If a mutated gene causes a necessary protein to be faulty or missing, gene therapy may be able to introduce a normal copy of the gene to restore the function of the protein.

    Webinars

    • MAY 08, 2019 | 9:00 AM
      Development of an Arrayed Whole Human Genome KO Library for Functional Genomics Screening, Using an Optimized Multi-sgRNA Approach
      Development of an Arrayed Whole Human Genome KO Library for Functional...
      Arrayed gene knockout (KO) libraries represent a valuable resource for performing functional genomics screening. Current generation arrayed KO libraries for the whole human genome rely on eit...
      Speaker: Kevin Holden, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      Sponsored By: Synthego
      1
      MAY 08, 2019 | 7:30 AM
      C.E. CREDITS
      Keynote Presentation: Interpreting the Zero $ Genome via Base Editing, Organoids & in Situ Omics
      Keynote Presentation: Interpreting the Zero $ Genome via Base...
      To interpret genome sequence from telomere to telomere, it is helpful end-to-end haplotypes with single-molecule epigenetics overlays, via in situ omics at sub-cellular (20 nm) resolution an...
      Speaker: George Church, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      2
      MAY 08, 2019 | 6:00 AM
      Upgrading the CRISPR Toolbox - New Strategies Sharpen the CRISPR-Cas9 Scissors Utilizing Visualization and Chromatic Accessibility
      Upgrading the CRISPR Toolbox - New Strategies Sharpen the CRISPR-Cas9...
      In this webinar, we will discuss our most recent additions to our CRISPR protein portfolio, the GFP-SpCas9 and GFP-eCas9 fusion proteins. The two GFP-Cas9 fusion proteins offer great visualiz...
      Speaker: Michelle Ding, M.S. , Yanfang Jiang, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      Sponsored By: MilliporeSigma
      1
      MAY 08, 2019 | 6:00 AM
      C.E. CREDITS
      Novel DNA Methylation in Mammals
      Novel DNA Methylation in Mammals
      Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA. Although the critical role of DNA 5-methylcytosine (5mC) in the regulation of transcription is recognize...
      Speaker: Tao Wu, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      2
      MAR 28, 2019 | 12:00 PM
      The Intersection of Nutrition, Microbiome and Medical Cannabis
      The Intersection of Nutrition, Microbiome and Medical Cannabis
      Whole food plant-based diets and medical cannabis have shared and continues to share similar levels of scrutiny, doubt, and stigma by the traditional medical community. One reason for the med...
      Speaker: Debra Kimless, MD
      Presented at: Cannabis Sciences Virtual Event Series 2019
      6
      MAR 26, 2019 | 2:00 PM
      The Role of Endosomes in Prostate Cancer
      The Role of Endosomes in Prostate Cancer
      DATE:  March 26, 2019TIME:  2:00pm PDT, 5:00pm EDT  Prostate cancer is the second most common form of cancer in males, affecting one in eight men by the time t...
      Speaker: Ian Johnson, BSc., Ph.D
      Sponsored By: Thermo Fisher Scientific/Gibco
      7
      MAR 13, 2019 | 6:00 AM
      Keynote Presentation: Updates from the NIH BRAIN Initiative
      Keynote Presentation: Updates from the NIH BRAIN Initiative
      Joshua Gordon, M.D., Ph.D., Director of the National Institute of Mental Health, will provide an overview of challenges and opportunities in mental health research. Dr. Gordon will present em...
      Speaker: Joshua A. Gordon, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2019
      3
      FEB 27, 2019 | 3:00 PM
      BASKET Trials: Biomarker Driven Drug Development
      BASKET Trials: Biomarker Driven Drug Development
      Dramatic responses observed with targeted agents in the ‘right’ genomic context have fueled large scale sequencing efforts to identify ‘effective’ treatments for a giv...
      Speaker: Shivaani Kummar, MD, FACP
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      FEB 27, 2019 | 10:30 AM
      The Current State-of-the-Art Tissue Expression Analysis Platform for Detection & Quantification of Target & Biomarker mRNAs, Splice Variants and Mutations in Preclinical & Clinical Tissues
      The Current State-of-the-Art Tissue Expression Analysis Platform...
      Advanced Cell Diagnostics’ RNAscope products and assay services are utilized widely for tissue-based gene expression analysis in early target validation, preclinical animal efficacy and...
      Speaker: Christopher Bunker, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: Advanced Cell Diagnostics
      1
      FEB 27, 2019 | 8:00 AM
      Prepare for success: GMP cell banks as part of a staged, standardized, platform-style cell production process
      Prepare for success: GMP cell banks as part of a staged, standardized,...
      DATE:  February 27, 2019TIME:  8:00am PST Pluripotent stem cells (PSCs) can form any tissue or cell in the body, and are the ideal starting material to manufacture...
      Speaker: Benjamin Fryer
      Sponsored By: Thermo Fisher Scientific/Gibco
      9
      FEB 27, 2019 | 7:30 AM
      Keynote Presentation: Second Harmonic Generation Detection of Ras Conformational Changes and Discovery of a Novel Small-Molecule Binder
      Keynote Presentation: Second Harmonic Generation Detection of...
      Second harmonic generation (SHG) is a biophysical method that sensitively measures real-time conformational change of biomolecules attached to membranes. SHG has recently been applied to dete...
      Speaker: Frank McCormick, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 6:00 AM
      Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders Using Ingenuity Pathway Analysis Software and OmicSoft OncoLand Datasets from QIAGEN
      Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders...
      The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
      Speaker: Devendra Mistry, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: QIAGEN
      1
      FEB 26, 2019 | 11:00 AM
      Osteosarcoma research
      Osteosarcoma research
      DATE:  February 26, 2019TIME:  11:00am PST, 2:00pm EST Osteosarcoma is the most common type of primary bone cancer affecting adolescents and children attributed to...
      Speaker: Luke Tattersall, BSc Biomedical Sciences, PhD Candidate
      Sponsored By: Thermo Fisher Scientific/Gibco
      3
      FEB 13, 2019 | 7:30 AM
      Keynote Presentation: Modernizing Drug Development Through Digital Transformation and Non-Traditional Models
      Keynote Presentation: Modernizing Drug Development Through Digital...
      Digitalization has transformed virtually every industry, but it has been slow to gain traction within the preclinical phase of the drug development journey. Recent advances in digital vivariu...
      Speaker: Szczepan Baran, VMD, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      6
      JAN 31, 2019 | 7:30 AM
      Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based Gene Delivery for Targeted Treatment of HER2-Positive Breast Cancer in Mice by Prodrugs - A New Gene-Delivered Enzyme Prodrug
      Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based...
      Prodrugs are harmless in their native state, as they are not targeted by human enzymes. But they can be converted into highly toxic compounds (the “drug”) by viral or bacterial en...
      Speaker: A.C. Matin, PhD
      Presented at: BioProcessing Virtual Event Series 2019
      1
      JAN 31, 2019 | 6:00 AM
      Overcoming Challenges in EuCODE Cell Culture Platform Development
      Overcoming Challenges in EuCODE Cell Culture Platform Development
      Ambrx’s mammalian expression platform (EuCODE™) enables non-native amino acids (nnAAs) through an expanded genetic code to both generate novel bio-therapeutics and to optimize the...
      Speaker: Weimin Lin, PhD
      Presented at: BioProcessing Virtual Event Series 2019
      3
      JAN 29, 2019 | 9:00 AM
      Targeting prostate cancer stem cells with T cell immunotherapy
      Targeting prostate cancer stem cells with T cell immunotherapy
      DATE:    January 29. 2019TIME:    09:00am PST, 12:00pm EST In healthy tissue, a reservoir of stem cells gives rise to non-stem cells while simul...
      Speaker: Amy Codd
      Sponsored By: Thermo Fisher Scientific/Gibco
      10 2
      JAN 15, 2019 | 12:00 AM
      Flexible manufacturing strategies for cell and gene therapy products
      Flexible manufacturing strategies for cell and gene therapy products
      DATE: January 15, 2018TIME:  4:00pm SGTPThere is a clear call to automate manufacturing for cell and gene therapy products, but when should you automate? In this session, we...
      Speaker: Wenyan Leong, PhD
      Sponsored By: TERUMO BCT
      6
      DEC 13, 2018 | 9:00 AM
      Optimizing Treatment Options for HER2+/ ER+ Breast Cancer using Models of Endocrine Resistance
      Optimizing Treatment Options for HER2+/ ER+ Breast Cancer using...
      DATE: December 13 15,2018TIME: 09:00am PST, 12:00pm EST Breast cancers are classified into three main subtypes according to their receptor status: estrogen receptor-positive...
      Speaker: Hillary Stires, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      3
      DEC 12, 2018 | 8:00 AM
      Evolution in the Manufacturing of Cellular Therapies- lessons learned and current solutions
      Evolution in the Manufacturing of Cellular Therapies- lessons...
      DATE: December 012, 2018TIME: 08:00 PSTImmunotherapy is a powerful treatment that harnesses the body’s immune system in the fight against cancer. With optimized cell therapy,...
      Speaker: Neil Kayal
      Sponsored By: Beckman Coulter Life Sciences
      5
      DEC 06, 2018 | 9:00 AM
      Cell and Gene Therapy Solutions: Enabling PSC Translation Workflows
      Cell and Gene Therapy Solutions: Enabling PSC Translation Workflows
      DATE:   December 6, 2018TIME:    9:00am PST, 12:00pm EST Induced pluripotent stem cells (iPSC) intended for translational applications need to be of...
      Speaker: Tia Hexom, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      DEC 06, 2018 | 7:00 AM
      Image-based screening for precision medicine and immunotherapy
      Image-based screening for precision medicine and immunotherapy
      DATE: December 06, 2018TIME:  7:00AM PSTHigh-throughput confocal microscopy has changed the way drug screening can be performed, by enabling the detection of single-cell pheno...
      Speaker: Dr. Gregory Vladimer
      Sponsored By: Revvity
      6
      NOV 15, 2018 | 9:00 AM
      Best Practice Strategies and Tools for Scaling Clinical Bioinformatics
      Best Practice Strategies and Tools for Scaling Clinical Bioinformatics
      Clinical testing with next generation sequencing requires a complex bioinformatics pipeline to process raw DNA sequence into  interpretable variants for medical reporting. With sequencin...
      Speaker: Elaine Gee, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2018
      1
      NOV 15, 2018 | 2:00 AM
      Towards commercial manufacture of pluripotent stem cell derived therapies
      Towards commercial manufacture of pluripotent stem cell derived...
      In contrast to autologous cell therapies, allogeneic therapies do not require collection of starting material from patients and could; be manufactured in larger batches, be made available &ld...
      Speaker: Rhys Macown
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      10
    MAY 08, 2019 | 9:00 AM
    Development of an Arrayed Whole Human Genome KO Library for Functional Genomics Screening, Using an Optimized Multi-sgRNA Approach
    Development of an Arrayed Whole Human Genome KO Library for Functional...
    Arrayed gene knockout (KO) libraries represent a valuable resource for performing functional genomics screening. Current generation arrayed KO libraries for the whole human genome rely on eit...
    Speaker: Kevin Holden, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    Sponsored By: Synthego
    1
    MAY 08, 2019 | 7:30 AM
    C.E. CREDITS
    Keynote Presentation: Interpreting the Zero $ Genome via Base Editing, Organoids & in Situ Omics
    Keynote Presentation: Interpreting the Zero $ Genome via Base...
    To interpret genome sequence from telomere to telomere, it is helpful end-to-end haplotypes with single-molecule epigenetics overlays, via in situ omics at sub-cellular (20 nm) resolution an...
    Speaker: George Church, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    2
    MAY 08, 2019 | 6:00 AM
    Upgrading the CRISPR Toolbox - New Strategies Sharpen the CRISPR-Cas9 Scissors Utilizing Visualization and Chromatic Accessibility
    Upgrading the CRISPR Toolbox - New Strategies Sharpen the CRISPR-Cas9...
    In this webinar, we will discuss our most recent additions to our CRISPR protein portfolio, the GFP-SpCas9 and GFP-eCas9 fusion proteins. The two GFP-Cas9 fusion proteins offer great visualiz...
    Speaker: Michelle Ding, M.S. , Yanfang Jiang, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    Sponsored By: MilliporeSigma
    1
    MAY 08, 2019 | 6:00 AM
    C.E. CREDITS
    Novel DNA Methylation in Mammals
    Novel DNA Methylation in Mammals
    Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA. Although the critical role of DNA 5-methylcytosine (5mC) in the regulation of transcription is recognize...
    Speaker: Tao Wu, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    2
    MAR 28, 2019 | 12:00 PM
    The Intersection of Nutrition, Microbiome and Medical Cannabis
    The Intersection of Nutrition, Microbiome and Medical Cannabis
    Whole food plant-based diets and medical cannabis have shared and continues to share similar levels of scrutiny, doubt, and stigma by the traditional medical community. One reason for the med...
    Speaker: Debra Kimless, MD
    Presented at: Cannabis Sciences Virtual Event Series 2019
    6
     
     
  • MAR 26, 2019 | 2:00 PM
    The Role of Endosomes in Prostate Cancer
    The Role of Endosomes in Prostate Cancer
    DATE:  March 26, 2019TIME:  2:00pm PDT, 5:00pm EDT  Prostate cancer is the second most common form of cancer in males, affecting one in eight men by the time t...
    Speaker: Ian Johnson, BSc., Ph.D
    Sponsored By: Thermo Fisher Scientific/Gibco
    7
    MAR 13, 2019 | 6:00 AM
    Keynote Presentation: Updates from the NIH BRAIN Initiative
    Keynote Presentation: Updates from the NIH BRAIN Initiative
    Joshua Gordon, M.D., Ph.D., Director of the National Institute of Mental Health, will provide an overview of challenges and opportunities in mental health research. Dr. Gordon will present em...
    Speaker: Joshua A. Gordon, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2019
    3
    FEB 27, 2019 | 3:00 PM
    BASKET Trials: Biomarker Driven Drug Development
    BASKET Trials: Biomarker Driven Drug Development
    Dramatic responses observed with targeted agents in the ‘right’ genomic context have fueled large scale sequencing efforts to identify ‘effective’ treatments for a giv...
    Speaker: Shivaani Kummar, MD, FACP
    Presented at: Drug Discovery Virtual Event Series 2019
    2
    FEB 27, 2019 | 10:30 AM
    The Current State-of-the-Art Tissue Expression Analysis Platform for Detection & Quantification of Target & Biomarker mRNAs, Splice Variants and Mutations in Preclinical & Clinical Tissues
    The Current State-of-the-Art Tissue Expression Analysis Platform...
    Advanced Cell Diagnostics’ RNAscope products and assay services are utilized widely for tissue-based gene expression analysis in early target validation, preclinical animal efficacy and...
    Speaker: Christopher Bunker, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: Advanced Cell Diagnostics
    1
    FEB 27, 2019 | 8:00 AM
    Prepare for success: GMP cell banks as part of a staged, standardized, platform-style cell production process
    Prepare for success: GMP cell banks as part of a staged, standardized,...
    DATE:  February 27, 2019TIME:  8:00am PST Pluripotent stem cells (PSCs) can form any tissue or cell in the body, and are the ideal starting material to manufacture...
    Speaker: Benjamin Fryer
    Sponsored By: Thermo Fisher Scientific/Gibco
    9
     
     
  • FEB 27, 2019 | 7:30 AM
    Keynote Presentation: Second Harmonic Generation Detection of Ras Conformational Changes and Discovery of a Novel Small-Molecule Binder
    Keynote Presentation: Second Harmonic Generation Detection of...
    Second harmonic generation (SHG) is a biophysical method that sensitively measures real-time conformational change of biomolecules attached to membranes. SHG has recently been applied to dete...
    Speaker: Frank McCormick, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 6:00 AM
    Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders Using Ingenuity Pathway Analysis Software and OmicSoft OncoLand Datasets from QIAGEN
    Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders...
    The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
    Speaker: Devendra Mistry, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: QIAGEN
    1
    FEB 26, 2019 | 11:00 AM
    Osteosarcoma research
    Osteosarcoma research
    DATE:  February 26, 2019TIME:  11:00am PST, 2:00pm EST Osteosarcoma is the most common type of primary bone cancer affecting adolescents and children attributed to...
    Speaker: Luke Tattersall, BSc Biomedical Sciences, PhD Candidate
    Sponsored By: Thermo Fisher Scientific/Gibco
    3
    FEB 13, 2019 | 7:30 AM
    Keynote Presentation: Modernizing Drug Development Through Digital Transformation and Non-Traditional Models
    Keynote Presentation: Modernizing Drug Development Through Digital...
    Digitalization has transformed virtually every industry, but it has been slow to gain traction within the preclinical phase of the drug development journey. Recent advances in digital vivariu...
    Speaker: Szczepan Baran, VMD, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    6
    JAN 31, 2019 | 7:30 AM
    Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based Gene Delivery for Targeted Treatment of HER2-Positive Breast Cancer in Mice by Prodrugs - A New Gene-Delivered Enzyme Prodrug
    Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based...
    Prodrugs are harmless in their native state, as they are not targeted by human enzymes. But they can be converted into highly toxic compounds (the “drug”) by viral or bacterial en...
    Speaker: A.C. Matin, PhD
    Presented at: BioProcessing Virtual Event Series 2019
    1
     
     
  • JAN 31, 2019 | 6:00 AM
    Overcoming Challenges in EuCODE Cell Culture Platform Development
    Overcoming Challenges in EuCODE Cell Culture Platform Development
    Ambrx’s mammalian expression platform (EuCODE™) enables non-native amino acids (nnAAs) through an expanded genetic code to both generate novel bio-therapeutics and to optimize the...
    Speaker: Weimin Lin, PhD
    Presented at: BioProcessing Virtual Event Series 2019
    3
    JAN 29, 2019 | 9:00 AM
    Targeting prostate cancer stem cells with T cell immunotherapy
    Targeting prostate cancer stem cells with T cell immunotherapy
    DATE:    January 29. 2019TIME:    09:00am PST, 12:00pm EST In healthy tissue, a reservoir of stem cells gives rise to non-stem cells while simul...
    Speaker: Amy Codd
    Sponsored By: Thermo Fisher Scientific/Gibco
    10 2
    JAN 15, 2019 | 12:00 AM
    Flexible manufacturing strategies for cell and gene therapy products
    Flexible manufacturing strategies for cell and gene therapy products
    DATE: January 15, 2018TIME:  4:00pm SGTPThere is a clear call to automate manufacturing for cell and gene therapy products, but when should you automate? In this session, we...
    Speaker: Wenyan Leong, PhD
    Sponsored By: TERUMO BCT
    6
    DEC 13, 2018 | 9:00 AM
    Optimizing Treatment Options for HER2+/ ER+ Breast Cancer using Models of Endocrine Resistance
    Optimizing Treatment Options for HER2+/ ER+ Breast Cancer using...
    DATE: December 13 15,2018TIME: 09:00am PST, 12:00pm EST Breast cancers are classified into three main subtypes according to their receptor status: estrogen receptor-positive...
    Speaker: Hillary Stires, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    3
    DEC 12, 2018 | 8:00 AM
    Evolution in the Manufacturing of Cellular Therapies- lessons learned and current solutions
    Evolution in the Manufacturing of Cellular Therapies- lessons...
    DATE: December 012, 2018TIME: 08:00 PSTImmunotherapy is a powerful treatment that harnesses the body’s immune system in the fight against cancer. With optimized cell therapy,...
    Speaker: Neil Kayal
    Sponsored By: Beckman Coulter Life Sciences
    5
     
     
  • DEC 06, 2018 | 9:00 AM
    Cell and Gene Therapy Solutions: Enabling PSC Translation Workflows
    Cell and Gene Therapy Solutions: Enabling PSC Translation Workflows
    DATE:   December 6, 2018TIME:    9:00am PST, 12:00pm EST Induced pluripotent stem cells (iPSC) intended for translational applications need to be of...
    Speaker: Tia Hexom, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
    DEC 06, 2018 | 7:00 AM
    Image-based screening for precision medicine and immunotherapy
    Image-based screening for precision medicine and immunotherapy
    DATE: December 06, 2018TIME:  7:00AM PSTHigh-throughput confocal microscopy has changed the way drug screening can be performed, by enabling the detection of single-cell pheno...
    Speaker: Dr. Gregory Vladimer
    Sponsored By: Revvity
    6
    NOV 15, 2018 | 9:00 AM
    Best Practice Strategies and Tools for Scaling Clinical Bioinformatics
    Best Practice Strategies and Tools for Scaling Clinical Bioinformatics
    Clinical testing with next generation sequencing requires a complex bioinformatics pipeline to process raw DNA sequence into  interpretable variants for medical reporting. With sequencin...
    Speaker: Elaine Gee, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2018
    1
    NOV 15, 2018 | 2:00 AM
    Towards commercial manufacture of pluripotent stem cell derived therapies
    Towards commercial manufacture of pluripotent stem cell derived...
    In contrast to autologous cell therapies, allogeneic therapies do not require collection of starting material from patients and could; be manufactured in larger batches, be made available &ld...
    Speaker: Rhys Macown
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    10
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