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Lungs
The lungs are a pair of spongy, air-filled organs located on either side of the chest (thorax). The trachea (windpipe) conducts inhaled air into the lungs through its tubular branches, called bronchi. The main function of the lungs is the process of gas exchange called respiration (or breathing). Lungs are inside of your rib cage.
SEP 30, 2015 | 12:00 PM
Hepatocellular carcinoma (HCC) is a significant contributor to cancer-related mortality in the United States and worldwide. Current treatments are largely ineffective: single agent and combin...
SEP 30, 2015 | 7:30 AM
We have been developing methods to target drugs specifically to pathologic cells, thereby avoiding collateral toxicity to healthy cells. In the case of cancer, we have exploited up-regulation...
SEP 30, 2015 | 7:30 AM
Using the NSGTM mouse (NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ), JAX In Vivo Pharmacology Services has combined the human CD34+ hematopoietic stem cell engrafted NSGTM (hu-CD34 NSGTM) with human pat...
SEP 09, 2015 | 9:00 AM
DATE: September 9, 2015TIME: 9:00am PDT, 12:00PM EDTDriver mutations are causally implicated in tumorigenesis and disease progression, and they are defined by molecular abnormalities such as ...
MAY 13, 2015 | 3:00 PM
Genome Wide Association Studies (GWAS) and eQTL analyses are producing huge numbers of associations and show no signs of slowing. There are now more than 8,500 SNPs associated with more than...
MAR 04, 2015 | 8:00 AM
Every cell in the body can release several types of extracellular vesicles (EVs), often called ”exosomes” or ”microvesicles”. These vesicles carry a wide array of mole...
OCT 30, 2014 | 7:30 AM
Fusion genes play a central role in many cancer types. They have been used to classify malignancy, risk factors, disease prognosis, and companion diagnostic biomarkers for certain approved dr...
OCT 29, 2014 | 3:00 PM
Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
SEP 16, 2014 | 10:00 AM
Patients with chromosomal rearrangements resulting in fusion proteins are among the most responsive to published targeted therapy. For example, targeting of the EML4-ALK fusion in non-small c...
