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    Pre-clinical Research

    Pre-clinical Research: is a level of research that begins before clinical trials can begin, and during which important feasibility, constant testing and drug safety data are collected. The aim of a preclinical study is to collect data in support of the safety of the new treatment. Preclinical studies are required before clinical trials in humans can be started.

    Webinars

    • NOV 14, 2019 | 12:00 PM
      Thyroid autoimmunity and female infertility
      Thyroid autoimmunity and female infertility
      Thyroid autoimmunity (TAI) tends to be more common in women consulting for fertility problems. However, any underlying causal mechanism connecting TAI to fertility aspects is yet to be establ...
      Speaker: David Unuane, MD, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
      4
      NOV 14, 2019 | 10:30 AM
      Identifying the PIK3CA mutations that make a difference in breast cancer with the QIAGEN therascreen® PIK3CA RGQ PCR Kit
      Identifying the PIK3CA mutations that make a difference in breast...
      Breast cancer is the most frequently occurring form of cancer in women. While 5-year survival rates for localized disease approach 99%, cases of advanced breast cancer have a much poorer pro...
      Speaker: Benjamin Chaffey, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
      Sponsored By: QIAGEN
      1
      NOV 14, 2019 | 10:30 AM
      Interferences with thyroid function tests and patient safety
      Interferences with thyroid function tests and patient safety
      Thyroid function tests play a central role to assess thyroid function and are valuable companions for clinicians. The evolution of the tests is permanent and clinical laboratories are key pla...
      Speaker: Damien Gruson, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
      2
      NOV 14, 2019 | 9:00 AM
      Discovering latent knowledge by applying machine learning techniques to QIAGEN resources
      Discovering latent knowledge by applying machine learning techniques...
      Applying machine learning methods to structured, expert-curated content from scientific literature is a powerful way to discover latent knowledge. Building on the QIAGEN Knowledge Base, we us...
      Speaker: Jeff Green
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
      Sponsored By: QIAGEN
      1
      NOV 14, 2019 | 9:00 AM
      Drug testing in Regulatory Monitoring
      Drug testing in Regulatory Monitoring
      Random drug testing is used as a preventive and detection tool for drug or alcohol use, and medication compliance in the monitoring of regulatory and treatment compliance monitoring. Urine sc...
      Speaker: John Furman, PhD, MSN, COHN-S
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
      5 1
      NOV 14, 2019 | 9:00 AM
      The Role of Proficiency Testing in Achieving Global Outcomes for Hemoglobin A1c
      The Role of Proficiency Testing in Achieving Global Outcomes for...
      Central to the diagnosis and management of patients with diabetes mellitus is the measurement of hemoglobin A1c (HbA1c). Major studies have defined the therapeutic targets of HbA1c in order...
      Speaker: Paul Yip, PhD, FCACB, DABCC
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
      2
      NOV 14, 2019 | 7:30 AM
      Keynote Presentation: The Opioid Epidemic in Ohio - A Crime Laboratory Perspective
      Keynote Presentation: The Opioid Epidemic in Ohio - A Crime Laboratory...
      70,237 drug overdose deaths occurred in the United States in 2017 and opioids were involved in 47,600 of those deaths (67.8%).1 Ohio had the second highest rate of opioid overdose deaths in t...
      Speaker: Douglas Rohde, MS, F-ABC, MLT(ASCP)
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
      2
      NOV 14, 2019 | 6:00 AM
      High Resolution View of D4Z4 Repeat Regions for Studying Facioscapulohumeral Muscular Dystrophy (FSHD) Using Whole Genome Optical Mapping
      High Resolution View of D4Z4 Repeat Regions for Studying Facioscapulohumeral...
      Facioscapulohumeral muscular dystrophy (FSHD), one of the most common forms of progressive muscular dystrophies and is often conventionally diagnosed by Southern blot analysis. The accurate d...
      Speaker: Alka Chaubey, PhD, FACMG
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
      Sponsored By: Bionano
      2
      NOV 14, 2019 | 6:00 AM
      Future Directions of Sepsis Management: The Emergence of Artificial Intelligence and the Laboratory Diagnostic Ecosystem
      Future Directions of Sepsis Management: The Emergence of Artificial...
      Burn patients are at risk for organ dysfunction secondary to “burn shock” and sepsis. The initial 24 hours following major burn injury presents with significant hypotension due to...
      Speaker: Nam Tran, PhD, HCLD (ABB), FACB
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
      1
      NOV 06, 2019 | 6:00 AM
      Understanding the Pathogenesis of Human Influenza Virus: A Systems Virology Approach
      Understanding the Pathogenesis of Human Influenza Virus: A Systems...
      Multiple factors can affect and impact infection dynamics and virulence produced by influenza virus (IV) infections. Susceptibility factors and host responses can also have major effects in d...
      Speaker: Rafael Medina Silva, PhD
      Presented at: Influenza Virtual Event Series 2019
      1
      OCT 31, 2019 | 9:00 AM
      Investigation of Endothelial Cell Viability and Growth on 3D printed GelMa Vascular Networks
      Investigation of Endothelial Cell Viability and Growth on 3D printed...
      DATE: October 31, 2019TIME: 9:00am PDT, 12:00pm EDT INTRODUCTION: A major limitation for the development of 3D engineered tissues is the absence of viable and perfusable...
      Speaker: Chrisoula Chappell
      Sponsored By: Thermo Fisher Scientific/Gibco
      8
      OCT 10, 2019 | 9:00 AM
      Dynamic evolution of unstable genomes: insights from in vitro experiments and cancer genome analysis
      Dynamic evolution of unstable genomes: insights from in vitro...
      Copy-number alterations and chromosomal translocations are widespread in cancer and frequently causing oncogenic mutations that drive tumorigenesis and therapy resistance. Despite their preva...
      Speaker: Cheng-Zhong Zhang, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      1
      SEP 30, 2019 | 8:00 AM
      Discovery and Verification of eQTLs Associated with Lung Adenocarcinoma
      Discovery and Verification of eQTLs Associated with Lung Adenocarcinoma
      DATE: September 30, 2019TIME: 8:00am PDT, 11:00am EDT, 5:00pm CEST Expression quantitative trait loci (eQTLs) are SNPs that have an influence on expression levels of genes, and the ident...
      Speaker: Tommaso Dragani , Harita Veereshlingam, PhD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      9
      SEP 27, 2019 | 9:00 AM
      Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
      Investigating how Tpz-1 may be used as a novel therapeutic agent...
      DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
      Speaker: Jessica Hess
      Sponsored By: Thermo Fisher Scientific/Gibco
      5
      SEP 12, 2019 | 7:30 AM
      Keynote Presentation: Microbial Centric Aging: A Paradigm Shift
      Keynote Presentation: Microbial Centric Aging: A Paradigm Shift
      ....
      Speaker: John Thomas, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2019
      2
      AUG 29, 2019 | 8:00 AM
      Implementation of Helicobacter Pylori Stool Antigen Testing in a Large Metropolitan Center:  A Prospective Comparative Diagnostic Trial
      Implementation of Helicobacter Pylori Stool Antigen Testing in...
      Date: August 27, 2019Time: 11:00am PDT, 2:00pm EDTBackground: Clinical guidelines for H. pylori screening and post-treatment testing endorse the use of urea breath test (UBT), H. py...
      Speaker: Dylan Pillai, MD, PhD, FRCPC (C)
      Presented at: Discover More; Your Virtual Resource
      Sponsored By: Diasorin
      11
      AUG 15, 2019 | 9:00 AM
      Understanding and ameliorating radiation-induced damage to oligodendrocytes
      Understanding and ameliorating radiation-induced damage to oligodendrocytes
      DATE: August 15, 2019TIME: 9:00am PDT, 12:00pm EDT Radiation therapy is a critical tool for the treatment of brain tumors, however, exposure to high doses of ionizing radiation...
      Speaker: Alexandra Taraboletti, PHD
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      JUL 31, 2019 | 9:00 AM
      Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
      Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
      DATE: July 31, 2019TIME: 9:00am PT, 12:00pm ET The choroid plexus, which makes up the blood-cerebrospinal fluid barrier in the central nervous system (CNS), lines the ventricle...
      Speaker: Elizabeth Delery, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7 1
      JUL 30, 2019 | 6:00 AM
      Overview of the new ERA Guidelines: Changes and Revisions
      Overview of the new ERA Guidelines: Changes and Revisions
      DATE: July 30, 2019TIME: 6:00am PT, 9:00am ET The current version of the EMA Guideline for the environmental risk assessment of human drugs was published in 2006. This guidance...
      Speaker: Erick Nfon, PhD
      Sponsored By: Smithers
      4
      JUN 27, 2019 | 9:00 AM
      CANCER ON A CHIP: A microfluidic 2D and 3D cell culture system for studying cellular microenvironment
      CANCER ON A CHIP: A microfluidic 2D and 3D cell culture system...
      DATE: June 27, 2019TIME: 9:00am PDT, 12:00pm EDT At present cancer research focuses on three major areas viz. cancer diagnostics, drugs development, and next-generation therapi...
      Speaker: Vivek Kamat, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      12
      JUN 26, 2019 | 9:00 AM
      Sample Management vs. Inventory Management: What is the difference?
      Sample Management vs. Inventory Management: What is the difference?
      DATE: June 26, 2019TIME: 9:00am PDT, 12:00pm EDT An excessive number of software solutions are available to help manage your clinical, biobank, or biorepository sample inform...
      Speaker: Kathi Shea , Markus Albertini, PhD
      Sponsored By: Brooks Life Sciences
      6 2
      JUN 05, 2019 | 5:00 PM
      Everyday culture practice - Improving reproducibility in cell culture
      Everyday culture practice - Improving reproducibility in cell...
      DATE: June 5, 2019TIME: 8:00am PDT, 11:00am EDT, 5:00pm CEST Eukaryotic cell cultures respond to the most subtle influence. Apart from the risk of contamination, minimal chan...
      Speaker: Jessica Wagener, PhD
      Sponsored By: Eppendorf
      23 2
      MAY 23, 2019 | 9:00 AM
      Doing More with Less: Stem Cells Regulate Their Fate by Altering Their Stiffness
      Doing More with Less: Stem Cells Regulate Their Fate by Altering...
      DATE:  May 23, 2019TIME:   9:00am PDT, 12:00pm EDT Although mesenchymal stem/stromal cells (MSCs) chondrogenic differentiation has been thoroughly investigated...
      Speaker: Melika Sarem, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7
      MAY 16, 2019 | 4:00 PM
      Towards Standardized Workflows - A focus on microbiome insights
      Towards Standardized Workflows - A focus on microbiome insights
      DATE: May 16, 2019TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST The emergence of NGS is revolutionizing the microbiological sciences and transforming medicine. Deep sequencing has...
      Speaker: Rita Colwell, PhD , Christiane Honisch, PhD
      Sponsored By: Eppendorf
      10 2
    NOV 14, 2019 | 12:00 PM
    Thyroid autoimmunity and female infertility
    Thyroid autoimmunity and female infertility
    Thyroid autoimmunity (TAI) tends to be more common in women consulting for fertility problems. However, any underlying causal mechanism connecting TAI to fertility aspects is yet to be establ...
    Speaker: David Unuane, MD, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
    4
    NOV 14, 2019 | 10:30 AM
    Identifying the PIK3CA mutations that make a difference in breast cancer with the QIAGEN therascreen® PIK3CA RGQ PCR Kit
    Identifying the PIK3CA mutations that make a difference in breast...
    Breast cancer is the most frequently occurring form of cancer in women. While 5-year survival rates for localized disease approach 99%, cases of advanced breast cancer have a much poorer pro...
    Speaker: Benjamin Chaffey, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
    Sponsored By: QIAGEN
    1
    NOV 14, 2019 | 10:30 AM
    Interferences with thyroid function tests and patient safety
    Interferences with thyroid function tests and patient safety
    Thyroid function tests play a central role to assess thyroid function and are valuable companions for clinicians. The evolution of the tests is permanent and clinical laboratories are key pla...
    Speaker: Damien Gruson, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
    2
    NOV 14, 2019 | 9:00 AM
    Discovering latent knowledge by applying machine learning techniques to QIAGEN resources
    Discovering latent knowledge by applying machine learning techniques...
    Applying machine learning methods to structured, expert-curated content from scientific literature is a powerful way to discover latent knowledge. Building on the QIAGEN Knowledge Base, we us...
    Speaker: Jeff Green
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
    Sponsored By: QIAGEN
    1
    NOV 14, 2019 | 9:00 AM
    Drug testing in Regulatory Monitoring
    Drug testing in Regulatory Monitoring
    Random drug testing is used as a preventive and detection tool for drug or alcohol use, and medication compliance in the monitoring of regulatory and treatment compliance monitoring. Urine sc...
    Speaker: John Furman, PhD, MSN, COHN-S
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
    5 1
     
     
  • NOV 14, 2019 | 9:00 AM
    The Role of Proficiency Testing in Achieving Global Outcomes for Hemoglobin A1c
    The Role of Proficiency Testing in Achieving Global Outcomes for...
    Central to the diagnosis and management of patients with diabetes mellitus is the measurement of hemoglobin A1c (HbA1c). Major studies have defined the therapeutic targets of HbA1c in order...
    Speaker: Paul Yip, PhD, FCACB, DABCC
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
    2
    NOV 14, 2019 | 7:30 AM
    Keynote Presentation: The Opioid Epidemic in Ohio - A Crime Laboratory Perspective
    Keynote Presentation: The Opioid Epidemic in Ohio - A Crime Laboratory...
    70,237 drug overdose deaths occurred in the United States in 2017 and opioids were involved in 47,600 of those deaths (67.8%).1 Ohio had the second highest rate of opioid overdose deaths in t...
    Speaker: Douglas Rohde, MS, F-ABC, MLT(ASCP)
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
    2
    NOV 14, 2019 | 6:00 AM
    High Resolution View of D4Z4 Repeat Regions for Studying Facioscapulohumeral Muscular Dystrophy (FSHD) Using Whole Genome Optical Mapping
    High Resolution View of D4Z4 Repeat Regions for Studying Facioscapulohumeral...
    Facioscapulohumeral muscular dystrophy (FSHD), one of the most common forms of progressive muscular dystrophies and is often conventionally diagnosed by Southern blot analysis. The accurate d...
    Speaker: Alka Chaubey, PhD, FACMG
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
    Sponsored By: Bionano
    2
    NOV 14, 2019 | 6:00 AM
    Future Directions of Sepsis Management: The Emergence of Artificial Intelligence and the Laboratory Diagnostic Ecosystem
    Future Directions of Sepsis Management: The Emergence of Artificial...
    Burn patients are at risk for organ dysfunction secondary to “burn shock” and sepsis. The initial 24 hours following major burn injury presents with significant hypotension due to...
    Speaker: Nam Tran, PhD, HCLD (ABB), FACB
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
    1
    NOV 06, 2019 | 6:00 AM
    Understanding the Pathogenesis of Human Influenza Virus: A Systems Virology Approach
    Understanding the Pathogenesis of Human Influenza Virus: A Systems...
    Multiple factors can affect and impact infection dynamics and virulence produced by influenza virus (IV) infections. Susceptibility factors and host responses can also have major effects in d...
    Speaker: Rafael Medina Silva, PhD
    Presented at: Influenza Virtual Event Series 2019
    1
     
     
  • OCT 31, 2019 | 9:00 AM
    Investigation of Endothelial Cell Viability and Growth on 3D printed GelMa Vascular Networks
    Investigation of Endothelial Cell Viability and Growth on 3D printed...
    DATE: October 31, 2019TIME: 9:00am PDT, 12:00pm EDT INTRODUCTION: A major limitation for the development of 3D engineered tissues is the absence of viable and perfusable...
    Speaker: Chrisoula Chappell
    Sponsored By: Thermo Fisher Scientific/Gibco
    8
    OCT 10, 2019 | 9:00 AM
    Dynamic evolution of unstable genomes: insights from in vitro experiments and cancer genome analysis
    Dynamic evolution of unstable genomes: insights from in vitro...
    Copy-number alterations and chromosomal translocations are widespread in cancer and frequently causing oncogenic mutations that drive tumorigenesis and therapy resistance. Despite their preva...
    Speaker: Cheng-Zhong Zhang, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    1
    SEP 30, 2019 | 8:00 AM
    Discovery and Verification of eQTLs Associated with Lung Adenocarcinoma
    Discovery and Verification of eQTLs Associated with Lung Adenocarcinoma
    DATE: September 30, 2019TIME: 8:00am PDT, 11:00am EDT, 5:00pm CEST Expression quantitative trait loci (eQTLs) are SNPs that have an influence on expression levels of genes, and the ident...
    Speaker: Tommaso Dragani , Harita Veereshlingam, PhD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    9
    SEP 27, 2019 | 9:00 AM
    Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
    Investigating how Tpz-1 may be used as a novel therapeutic agent...
    DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
    Speaker: Jessica Hess
    Sponsored By: Thermo Fisher Scientific/Gibco
    5
    SEP 12, 2019 | 7:30 AM
    Keynote Presentation: Microbial Centric Aging: A Paradigm Shift
    Keynote Presentation: Microbial Centric Aging: A Paradigm Shift
    ....
    Speaker: John Thomas, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2019
    2
     
     
  • AUG 29, 2019 | 8:00 AM
    Implementation of Helicobacter Pylori Stool Antigen Testing in a Large Metropolitan Center:  A Prospective Comparative Diagnostic Trial
    Implementation of Helicobacter Pylori Stool Antigen Testing in...
    Date: August 27, 2019Time: 11:00am PDT, 2:00pm EDTBackground: Clinical guidelines for H. pylori screening and post-treatment testing endorse the use of urea breath test (UBT), H. py...
    Speaker: Dylan Pillai, MD, PhD, FRCPC (C)
    Presented at: Discover More; Your Virtual Resource
    Sponsored By: Diasorin
    11
    AUG 15, 2019 | 9:00 AM
    Understanding and ameliorating radiation-induced damage to oligodendrocytes
    Understanding and ameliorating radiation-induced damage to oligodendrocytes
    DATE: August 15, 2019TIME: 9:00am PDT, 12:00pm EDT Radiation therapy is a critical tool for the treatment of brain tumors, however, exposure to high doses of ionizing radiation...
    Speaker: Alexandra Taraboletti, PHD
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
    JUL 31, 2019 | 9:00 AM
    Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
    Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
    DATE: July 31, 2019TIME: 9:00am PT, 12:00pm ET The choroid plexus, which makes up the blood-cerebrospinal fluid barrier in the central nervous system (CNS), lines the ventricle...
    Speaker: Elizabeth Delery, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    7 1
    JUL 30, 2019 | 6:00 AM
    Overview of the new ERA Guidelines: Changes and Revisions
    Overview of the new ERA Guidelines: Changes and Revisions
    DATE: July 30, 2019TIME: 6:00am PT, 9:00am ET The current version of the EMA Guideline for the environmental risk assessment of human drugs was published in 2006. This guidance...
    Speaker: Erick Nfon, PhD
    Sponsored By: Smithers
    4
    JUN 27, 2019 | 9:00 AM
    CANCER ON A CHIP: A microfluidic 2D and 3D cell culture system for studying cellular microenvironment
    CANCER ON A CHIP: A microfluidic 2D and 3D cell culture system...
    DATE: June 27, 2019TIME: 9:00am PDT, 12:00pm EDT At present cancer research focuses on three major areas viz. cancer diagnostics, drugs development, and next-generation therapi...
    Speaker: Vivek Kamat, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    12
     
     
  • JUN 26, 2019 | 9:00 AM
    Sample Management vs. Inventory Management: What is the difference?
    Sample Management vs. Inventory Management: What is the difference?
    DATE: June 26, 2019TIME: 9:00am PDT, 12:00pm EDT An excessive number of software solutions are available to help manage your clinical, biobank, or biorepository sample inform...
    Speaker: Kathi Shea , Markus Albertini, PhD
    Sponsored By: Brooks Life Sciences
    6 2
    JUN 05, 2019 | 5:00 PM
    Everyday culture practice - Improving reproducibility in cell culture
    Everyday culture practice - Improving reproducibility in cell...
    DATE: June 5, 2019TIME: 8:00am PDT, 11:00am EDT, 5:00pm CEST Eukaryotic cell cultures respond to the most subtle influence. Apart from the risk of contamination, minimal chan...
    Speaker: Jessica Wagener, PhD
    Sponsored By: Eppendorf
    23 2
    MAY 23, 2019 | 9:00 AM
    Doing More with Less: Stem Cells Regulate Their Fate by Altering Their Stiffness
    Doing More with Less: Stem Cells Regulate Their Fate by Altering...
    DATE:  May 23, 2019TIME:   9:00am PDT, 12:00pm EDT Although mesenchymal stem/stromal cells (MSCs) chondrogenic differentiation has been thoroughly investigated...
    Speaker: Melika Sarem, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    7
    MAY 16, 2019 | 4:00 PM
    Towards Standardized Workflows - A focus on microbiome insights
    Towards Standardized Workflows - A focus on microbiome insights
    DATE: May 16, 2019TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST The emergence of NGS is revolutionizing the microbiological sciences and transforming medicine. Deep sequencing has...
    Speaker: Rita Colwell, PhD , Christiane Honisch, PhD
    Sponsored By: Eppendorf
    10 2
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