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T-cell Receptor
T-Cell Receptor: or TCR, is a molecule found on the surface of T cells, or T lymphocytes, that is responsible for recognizing fragments of antigen as peptides bound to major histocompatibility complex molecules.
JUL 26, 2023 | 11:20 AM
Chimeric antigen receptor (CAR)-reprogrammed immune cells offer exciting therapeutic potential for addressing oncology, autoimmune diseases, transplant medicine, and infections. However, cur...
MAY 16, 2023 | 8:00 AM
The therapeutic use of chimeric antigen receptor T cells has achieved significant success in the treatment of B cells malignancies. Despite promising results in mouse tumor models, a similar...
MAY 02, 2023 | 8:00 AM
Abstract Learning Objectives Define a tertiary lymphoid structure in human cancer Describe the tumor microenvironment factors that influence the formation of tertiary lymphoid structures Ide...
MAR 30, 2023 | 5:00 PM
Date: March 30, 2023 Time: 5:00pm (PST), 8:00pm (EST) March 31, 2023 9:00am (JST) Chimeric antigen receptor T cell (CAR-T) therapy is still challenging in targeting solid malignancies. The q...
MAR 30, 2023 | 1:00 PM
The circulating T-cell receptor (TCR) repertoire is a dynamic representation of overall immune responses in an individual. Here we aimed to correlate pre-treatment circulating TCR repertoire...
MAR 30, 2023 | 1:00 PM
The circulating T-cell receptor (TCR) repertoire is a dynamic representation of overall immune responses in an individual. Here we aimed to correlate pre-treatment circulating TCR repertoire...
NOV 08, 2022 | 8:00 AM
Date: November 08, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CEST) While flow cytometry shines by its flexibility, it requires a high level of expertise in antibody panel development,...
APR 19, 2022 | 5:30 AM
Next-generation sequencing (NGS) has become a foundational tool for both biological research and in-vitro diagnostics, particularly in oncology, immunology, and detection of genetic disorder...
FEB 23, 2022 | 6:00 AM
Cancer still accounts for nearly 1 in every 4 deaths worldwide. New immunotherapies have the power to induce durable responses in patients with fatal cancers, but only a small percentage of...
AUG 25, 2021 | 7:30 AM
The misfolding of intrinsically disordered proteins (IDPs) such as tau and α-synuclein (αSyn) has been associated with the on-set and progression of Alzheimer’s (AD) and Pa...
NOV 04, 2020 | 11:00 AM
DATE: November 4th, 2020 TIME: 11:00am PST As cell therapies become more complex, the need for robust analytical tools to characterize such products as they enter the clinic has increased in...
OCT 08, 2020 | 9:00 AM
Mutations in the epidermal growth factor receptor gene (EGFR) and the known Kirsten rat sarcoma viral oncogene (KRAS) are significant drivers in the development of non-small-cell lung cancer...
