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    CRISPR-Cas9

    CRISPR-Cas9: Clustered regularly interspaced short palindromic repeats are segments of prokaryotic DNA containing short, repetitive base sequences. These play a key role in a bacterial defence system,and form the basis of a genome editing technology known as CRISPR/Cas9 that allows permanent modification of genes within organisms. The CRISPR/Cas system is a prokaryotic immune system that confers resistance to foreign genetic elements such as those present within plasmids and phages that provides a form of acquired immunity. It is a unique technology that enables geneticists and medical researchers to edit parts of the genome by removing, adding or altering sections of the DNA sequence.

    Trending News

    • DEC 07, 2017
      Genetics & Genomics
      Using CRISPR For Epigenetic Modifications
      Using CRISPR For Epigenetic Modifications
      CRISPR/Cas9 gene editing technology has been hailed as revolutionary, but the technique came with some caveats. Now, it ...
      Written By: Carmen Leitch
      2
      NOV 18, 2017
      Genetics & Genomics
      The Risks & Rewards of Genetically Altered Mosquitoes
      The Risks & Rewards of Genetically Altered Mosquitoes
      Mosquitoes with edited genomes have been created in the lab, with the aim of reducing disease and controlling mosquito p ...
      Written By: Carmen Leitch
      2
      NOV 16, 2017
      Genetics & Genomics
      A New and Improved Genome Editing Tool
      A New and Improved Genome Editing Tool
      Genome editing, now inspired by yeast, aims to turn a 'hacksaw to a scalpel.'
      Written By: Carmen Leitch
      1
      NOV 13, 2017
      Technology
      Breaking: First Real-Time Video of CRISPR editing DNA
      Breaking: First Real-Time Video of CRISPR editing DNA
      Through high-speed atomic-force microscopy, the scientists take us on an incredible journey into the realm of CRISPR at ...
      Written By: Julia Travers
      3
      OCT 27, 2017
      Genetics & Genomics
      Novel Enzyme can Make Precise Base Pair Edits
      Novel Enzyme can Make Precise Base Pair Edits
      Researchers have made many advances in gene-editing technology in recent years, and it's undergoing constant improvement ...
      Written By: Carmen Leitch
      2
      OCT 24, 2017
      Cell & Molecular Biology
      Editing Genes in the Brain with CRISPR/Cas9
      Editing Genes in the Brain with CRISPR/Cas9
      Relatively recent advancements in gene editing tools have completely revolutionized biomedical science, and now that tec ...
      Written By: Carmen Leitch
      2
      OCT 21, 2017
      Genetics & Genomics
      Understanding a Rare Liver Disorder so it can be Treated
      Understanding a Rare Liver Disorder so it can be Treated
      Scientists have learned more about a genetic disorder that affects the liver, revealing potential new therapeutic avenue ...
      Written By: Carmen Leitch
      2
      OCT 18, 2017
      Cancer
      The Genetic Cause of Liver Cancer Identified
      The Genetic Cause of Liver Cancer Identified
      Using gene-editing technology in mice, scientists implicate a new fusion gene in the development of liver cancer. Becaus ...
      Written By: Xuan Pham
      3
      OCT 11, 2017
      Chemistry & Physics
      Chemistry Nobel 2017 - Why Cryo-Electron Microscopy
      Chemistry Nobel 2017 - Why Cryo-Electron Microscopy
      Chemistry Nobel Laureate Jacques Dubochet, Joachim Frank, and Richard Henderson. Credit: The Royal Swedish Academy of Sc ...
      Written By: Daniel Duan
      3
      OCT 06, 2017
      Cell & Molecular Biology
      New CRISPR-Gold Tool Repairs Muscular Dystrophy in Mice
      New CRISPR-Gold Tool Repairs Muscular Dystrophy in Mice
      Scientists have created a new way to deliver CRISPR that doesn't require a virus, and that worked better than CRISPR-Cas ...
      Written By: Carmen Leitch
      2
      AUG 07, 2017
      Immunology
      Scanning Cancer's Genome to Uncover Resistance Genes
      Scanning Cancer's Genome to Uncover Resistance Genes
      Cancer can't hide from the immune system anymore - scientists are on the verge of identifying every single gene muta ...
      Written By: Kara Marker
      4
      AUG 03, 2017
      Cardiology
      Scientists Achieve Very First Safe Repair of Disease-Causing Mutation in Human Embryos
      Scientists Achieve Very First Safe Repair of Disease-Causing Mutation in Human Embryos
      Using in vitro fertilization (IVF), scientists are introducing genetic editing machinery into egg and sperm cells to pre ...
      Written By: Kara Marker
      3 1
      AUG 02, 2017
      Cell & Molecular Biology
      Genetic Mutation in Human Embryo is Successfully Corrected
      Genetic Mutation in Human Embryo is Successfully Corrected
      Researchers have made a breakthrough by successfully repairing a deleterious genetic mutation in a human embryo that cau ...
      Written By: Carmen Leitch
      1
      JUL 14, 2017
      Cell & Molecular Biology
      Anti-CRISPR Proteins can Reduce Off-target Effects
      Anti-CRISPR Proteins can Reduce Off-target Effects
      CRISPR-Cas9 is a gene editing tool has tremendous potential, and researchers are working to improve it.
      Written By: Carmen Leitch
      2
      JUL 06, 2017
      Cell & Molecular Biology
      Cause of Carey-Fineman-Ziter Syndrome, Potential Treatment ID'ed
      Cause of Carey-Fineman-Ziter Syndrome, Potential Treatment ID'ed
      This new data on a rare disease could help diagnose the disorder in new patients, and has led researchers to test new tr ...
      Written By: Carmen Leitch
      2
      JUL 01, 2017
      Cell & Molecular Biology
      Precise Visualization of CRISPR Tool Aims to Improve Accuracy
      Precise Visualization of CRISPR Tool Aims to Improve Accuracy
      The CRISPR gene-editing tool has been widely adopted since its relatively recent invention. Researchers have now visuali ...
      Written By: Carmen Leitch
      2 1
      MAY 22, 2017
      Cardiology
      First-Ever Genes Discovered to Cause Rare Congenital Heart Defect
      First-Ever Genes Discovered to Cause Rare Congenital Heart Defect
        For the first time, scientists discovered a genetic culprit for a severe congenital heart defect, hypoplastic lef ...
      Written By: Kara Marker
      3
      MAR 28, 2017
      Genetics & Genomics
      A Molecular On/Off Switch for CRISPR
      A Molecular On/Off Switch for CRISPR
      TSRI Scientists Reveal How Viruses Disable Bacterial Immune Systems LA JOLLA, CA – March 28, 2017 – Picture ...
      Written By: The Scripps Research Institute (TSRI)
      3
      MAR 11, 2017
      Cancer
      A new way to Alter Gene Expression may aid Leukemia Treatment
      A new way to Alter Gene Expression may aid Leukemia Treatment
      New work by scientists at Rockefeller University in New York could help young patients suffering from leukemia. They eng ...
      Written By: Carmen Leitch
      2
      FEB 25, 2017
      Videos
      How Pigs Can Help Transplant Patients Get Off the Waitlist
      How Pigs Can Help Transplant Patients Get Off the Waitlist
      The United Network for Organ Sharing (UNOS) tabulated that 122,563 people currently are in need of a lifesaving organ tr ...
      Written By: Xuan Pham
      6
      FEB 16, 2017
      Cell & Molecular Biology
      Engineering CRISPR to be a Better Disease Therapeutic
      Engineering CRISPR to be a Better Disease Therapeutic
      The CRISPR/Cas9 genome editing system has made a tremendous impact in the years since it's development. Scientists h ...
      Written By: Carmen Leitch
      4
      FEB 06, 2017
      Immunology
      Gene Variation Betrays Protective Cells in GI Tract
      Gene Variation Betrays Protective Cells in GI Tract
      The recent discovery of not just one, but multiple genes that fail to protect the gastrointestinal (GI) tract from infla ...
      Written By: Kara Marker
      3
      JAN 28, 2017
      Cell & Molecular Biology
      Chimera Advancements Boost Biomedical Therapy & Research
      Chimera Advancements Boost Biomedical Therapy & Research
      Chimeras have cells from two different organisms growing in the same animal. You might see some wild headlines about the ...
      Written By: Carmen Leitch
      2
      JAN 23, 2017
      Genetics & Genomics
      TSRI Scientists Create First Stable Semisynthetic Organism
      TSRI Scientists Create First Stable Semisynthetic Organism
      LA JOLLA, CA – January 23, 2017 – Life’s genetic code has only ever contained four natural bases. Thes ...
      Written By: The Scripps Research Institute (TSRI)
      4
    DEC 07, 2017
    Genetics & Genomics
    Using CRISPR For Epigenetic Modifications
    Using CRISPR For Epigenetic Modifications
    CRISPR/Cas9 gene editing technology has been hailed as revolutionary, but the technique came with some caveats. Now, it ...
    Written By: Carmen Leitch
    2
    NOV 18, 2017
    Genetics & Genomics
    The Risks & Rewards of Genetically Altered Mosquitoes
    The Risks & Rewards of Genetically Altered Mosquitoes
    Mosquitoes with edited genomes have been created in the lab, with the aim of reducing disease and controlling mosquito p ...
    Written By: Carmen Leitch
    2
    NOV 16, 2017
    Genetics & Genomics
    A New and Improved Genome Editing Tool
    A New and Improved Genome Editing Tool
    Genome editing, now inspired by yeast, aims to turn a 'hacksaw to a scalpel.'
    Written By: Carmen Leitch
    1
    NOV 13, 2017
    Technology
    Breaking: First Real-Time Video of CRISPR editing DNA
    Breaking: First Real-Time Video of CRISPR editing DNA
    Through high-speed atomic-force microscopy, the scientists take us on an incredible journey into the realm of CRISPR at ...
    Written By: Julia Travers
    3
    OCT 27, 2017
    Genetics & Genomics
    Novel Enzyme can Make Precise Base Pair Edits
    Novel Enzyme can Make Precise Base Pair Edits
    Researchers have made many advances in gene-editing technology in recent years, and it's undergoing constant improvement ...
    Written By: Carmen Leitch
    2
     
     
  • OCT 24, 2017
    Cell & Molecular Biology
    Editing Genes in the Brain with CRISPR/Cas9
    Editing Genes in the Brain with CRISPR/Cas9
    Relatively recent advancements in gene editing tools have completely revolutionized biomedical science, and now that tec ...
    Written By: Carmen Leitch
    2
    OCT 21, 2017
    Genetics & Genomics
    Understanding a Rare Liver Disorder so it can be Treated
    Understanding a Rare Liver Disorder so it can be Treated
    Scientists have learned more about a genetic disorder that affects the liver, revealing potential new therapeutic avenue ...
    Written By: Carmen Leitch
    2
    OCT 18, 2017
    Cancer
    The Genetic Cause of Liver Cancer Identified
    The Genetic Cause of Liver Cancer Identified
    Using gene-editing technology in mice, scientists implicate a new fusion gene in the development of liver cancer. Becaus ...
    Written By: Xuan Pham
    3
    OCT 11, 2017
    Chemistry & Physics
    Chemistry Nobel 2017 - Why Cryo-Electron Microscopy
    Chemistry Nobel 2017 - Why Cryo-Electron Microscopy
    Chemistry Nobel Laureate Jacques Dubochet, Joachim Frank, and Richard Henderson. Credit: The Royal Swedish Academy of Sc ...
    Written By: Daniel Duan
    3
    OCT 06, 2017
    Cell & Molecular Biology
    New CRISPR-Gold Tool Repairs Muscular Dystrophy in Mice
    New CRISPR-Gold Tool Repairs Muscular Dystrophy in Mice
    Scientists have created a new way to deliver CRISPR that doesn't require a virus, and that worked better than CRISPR-Cas ...
    Written By: Carmen Leitch
    2
     
     
  • AUG 07, 2017
    Immunology
    Scanning Cancer's Genome to Uncover Resistance Genes
    Scanning Cancer's Genome to Uncover Resistance Genes
    Cancer can't hide from the immune system anymore - scientists are on the verge of identifying every single gene muta ...
    Written By: Kara Marker
    4
    AUG 03, 2017
    Cardiology
    Scientists Achieve Very First Safe Repair of Disease-Causing Mutation in Human Embryos
    Scientists Achieve Very First Safe Repair of Disease-Causing Mutation in Human Embryos
    Using in vitro fertilization (IVF), scientists are introducing genetic editing machinery into egg and sperm cells to pre ...
    Written By: Kara Marker
    3 1
    AUG 02, 2017
    Cell & Molecular Biology
    Genetic Mutation in Human Embryo is Successfully Corrected
    Genetic Mutation in Human Embryo is Successfully Corrected
    Researchers have made a breakthrough by successfully repairing a deleterious genetic mutation in a human embryo that cau ...
    Written By: Carmen Leitch
    1
    JUL 14, 2017
    Cell & Molecular Biology
    Anti-CRISPR Proteins can Reduce Off-target Effects
    Anti-CRISPR Proteins can Reduce Off-target Effects
    CRISPR-Cas9 is a gene editing tool has tremendous potential, and researchers are working to improve it.
    Written By: Carmen Leitch
    2
    JUL 06, 2017
    Cell & Molecular Biology
    Cause of Carey-Fineman-Ziter Syndrome, Potential Treatment ID'ed
    Cause of Carey-Fineman-Ziter Syndrome, Potential Treatment ID'ed
    This new data on a rare disease could help diagnose the disorder in new patients, and has led researchers to test new tr ...
    Written By: Carmen Leitch
    2
     
     
  • JUL 01, 2017
    Cell & Molecular Biology
    Precise Visualization of CRISPR Tool Aims to Improve Accuracy
    Precise Visualization of CRISPR Tool Aims to Improve Accuracy
    The CRISPR gene-editing tool has been widely adopted since its relatively recent invention. Researchers have now visuali ...
    Written By: Carmen Leitch
    2 1
    MAY 22, 2017
    Cardiology
    First-Ever Genes Discovered to Cause Rare Congenital Heart Defect
    First-Ever Genes Discovered to Cause Rare Congenital Heart Defect
      For the first time, scientists discovered a genetic culprit for a severe congenital heart defect, hypoplastic lef ...
    Written By: Kara Marker
    3
    MAR 28, 2017
    Genetics & Genomics
    A Molecular On/Off Switch for CRISPR
    A Molecular On/Off Switch for CRISPR
    TSRI Scientists Reveal How Viruses Disable Bacterial Immune Systems LA JOLLA, CA – March 28, 2017 – Picture ...
    Written By: The Scripps Research Institute (TSRI)
    3
    MAR 11, 2017
    Cancer
    A new way to Alter Gene Expression may aid Leukemia Treatment
    A new way to Alter Gene Expression may aid Leukemia Treatment
    New work by scientists at Rockefeller University in New York could help young patients suffering from leukemia. They eng ...
    Written By: Carmen Leitch
    2
    FEB 25, 2017
    Videos
    How Pigs Can Help Transplant Patients Get Off the Waitlist
    How Pigs Can Help Transplant Patients Get Off the Waitlist
    The United Network for Organ Sharing (UNOS) tabulated that 122,563 people currently are in need of a lifesaving organ tr ...
    Written By: Xuan Pham
    6
     
     
  • FEB 16, 2017
    Cell & Molecular Biology
    Engineering CRISPR to be a Better Disease Therapeutic
    Engineering CRISPR to be a Better Disease Therapeutic
    The CRISPR/Cas9 genome editing system has made a tremendous impact in the years since it's development. Scientists h ...
    Written By: Carmen Leitch
    4
    FEB 06, 2017
    Immunology
    Gene Variation Betrays Protective Cells in GI Tract
    Gene Variation Betrays Protective Cells in GI Tract
    The recent discovery of not just one, but multiple genes that fail to protect the gastrointestinal (GI) tract from infla ...
    Written By: Kara Marker
    3
    JAN 28, 2017
    Cell & Molecular Biology
    Chimera Advancements Boost Biomedical Therapy & Research
    Chimera Advancements Boost Biomedical Therapy & Research
    Chimeras have cells from two different organisms growing in the same animal. You might see some wild headlines about the ...
    Written By: Carmen Leitch
    2
    JAN 23, 2017
    Genetics & Genomics
    TSRI Scientists Create First Stable Semisynthetic Organism
    TSRI Scientists Create First Stable Semisynthetic Organism
    LA JOLLA, CA – January 23, 2017 – Life’s genetic code has only ever contained four natural bases. Thes ...
    Written By: The Scripps Research Institute (TSRI)
    4
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