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    Follow

    CRISPR-Cas9

    CRISPR-Cas9: Clustered regularly interspaced short palindromic repeats are segments of prokaryotic DNA containing short, repetitive base sequences. These play a key role in a bacterial defence system,and form the basis of a genome editing technology known as CRISPR/Cas9 that allows permanent modification of genes within organisms. The CRISPR/Cas system is a prokaryotic immune system that confers resistance to foreign genetic elements such as those present within plasmids and phages that provides a form of acquired immunity. It is a unique technology that enables geneticists and medical researchers to edit parts of the genome by removing, adding or altering sections of the DNA sequence.

    Trending News

    • DEC 08, 2016
      Cell & Molecular Biology
      Natural Off-Switch for CRISPR/Cas9 Identified
      Natural Off-Switch for CRISPR/Cas9 Identified
      The CRISPR/Cas9 genome-editing tool set off a revolution in biomedicine. Natural features of bacterial immunity were uti ...
      Written By: Carmen Leitch
      2
      NOV 30, 2016
      Cell & Molecular Biology
      Allen Institute Announces Public Release of Fluorescent Stem Cell Lines
      Allen Institute Announces Public Release of Fluorescent Stem Cell Lines
      The Allen Institute for Cell Science was founded by a contribution by Paul G. Allen, a cofounder of Microsoft, in 2014. ...
      Written By: Carmen Leitch
      2
      NOV 12, 2016
      Videos
      Towards a Cure for Sickle Cell Anemia Through CRISPR
      Towards a Cure for Sickle Cell Anemia Through CRISPR
      The CRISPR/Cas9 genome technique has paved the way for the development of many biological advances not only in research, ...
      Written By: Carmen Leitch
      1
      OCT 17, 2016
      Immunology
      One Enzyme and the Innate Immune Response
      One Enzyme and the Innate Immune Response
      The innate immune system helps an infected cell in one of two ways: calling the troops to bring in effector immune cells ...
      Written By: Kara Marker
      4
      OCT 04, 2016
      Microbiology
      New Details on the Bacterial Immune System, CRISPR/Cas, Revealed
      New Details on the Bacterial Immune System, CRISPR/Cas, Revealed
      The CRISPR/Cas9 gene editing system was developed in 2014 and has since had a huge impact on research in molecular biolo ...
      Written By: Carmen Leitch
      3
      SEP 20, 2016
      Immunology
      This is how norovirus invades cells to make us sick
      This is how norovirus invades cells to make us sick
      Norovirus is the most common viral cause of diarrhea worldwide, but because of an inability to grow it in a lab, scienti ...
      Written By: Futurity (futurity.org)
      4
      SEP 16, 2016
      Videos
      CRISPR-Cas9 for Genetically Modified Humans?
      CRISPR-Cas9 for Genetically Modified Humans?
      Science portrayed in movies is, unsurprisingly, usually farfetched and largely separated from reality. However unrealist ...
      Written By: Kara Marker
      3
      SEP 13, 2016
      Microbiology
      Toxoplasma Genome Screen Reveals Parasitic Infection Mechanism
      Toxoplasma Genome Screen Reveals Parasitic Infection Mechanism
      After performing the first genome wide screen of Apicomplexa, researchers have identified a potential mechanism for the ...
      Written By: Carmen Leitch
      3
      AUG 31, 2016
      Cell & Molecular Biology
      New Genome Editing Technique Does not cut DNA
      New Genome Editing Technique Does not cut DNA
      Researchers have developed a genome editing technique that does not require DNA to be cleaved. Called Target-AID, the te ...
      Written By: Carmen Leitch
      4
      AUG 22, 2016
      Cell & Molecular Biology
      Cutting Edge Techniques Yield Potential Treatment for Rare Genetic Disease
      Cutting Edge Techniques Yield Potential Treatment for Rare Genetic Disease
      A research team led by Christopher J. Lengner of the University of Pennsylvania School of Veterinary Medicine and Brad J ...
      Written By: Carmen Leitch
      2
      JUL 13, 2016
      Health & Medicine
      Tendon, Heal Thyself!
      Tendon, Heal Thyself!
      LA JOLLA, CA – July 13, 2016 – With the Rio Olympics just weeks away, many are wondering how Jamaican sprint ...
      Written By: The Scripps Research Institute (TSRI)
      3
      JUN 24, 2016
      Cancer
      An Integrated Approach to Find Drug Targets in Rare Cancers
      An Integrated Approach to Find Drug Targets in Rare Cancers
      Rare cancers account for about 25% of cancer in adults and about 10% of pediatric cancer cases. Unfortunately, prognosis ...
      Written By: Cassidy Reich
      2
      JUN 23, 2016
      Cell & Molecular Biology
      NIH Approves Human CRISPR Trial Funded by Sean Parker
      NIH Approves Human CRISPR Trial Funded by Sean Parker
      The US government panel that evaluates gene therapy trials, the National Institute of Health’s Recombinant DNA Res ...
      Written By: Carmen Leitch
      4
      JUN 20, 2016
      Microbiology
      A Proposal: Replace lab Essential E.coli With Fast-Growing Bacteria
      A Proposal: Replace lab Essential E.coli With Fast-Growing Bacteria
      A team of researchers at Harvard has made a revolutionary proposition to the world of molecular biology. They suggest th ...
      Written By: Carmen Leitch
      3
      JUN 17, 2016
      Cell & Molecular Biology
      Federal Safety Board to Consider First Use of CRISPR on Human
      Federal Safety Board to Consider First Use of CRISPR on Human
      A trial of the CRISPR/Cas9 gene editing technology has been proposed for use in a human patient. The National Institute ...
      Written By: Carmen Leitch
      1
      JUN 13, 2016
      Cell & Molecular Biology
      Gene Drive Technology Gets Prudent Stamp of Approval
      Gene Drive Technology Gets Prudent Stamp of Approval
      Gene drive is a term used to describe the preferential dissemination of some versions of a gene to future generations.&n ...
      Written By: Carmen Leitch
      3
      JUN 10, 2016
      Genetics & Genomics
      CRISPR-Cpf1 Increases Efficiency of Genome Editing
      CRISPR-Cpf1 Increases Efficiency of Genome Editing
      CRISPR-Cas9 is the discovery that took the scientific community by storm, the technology of the century. In a new study ...
      Written By: Kara Marker
      1
      JUN 08, 2016
      Immunology
      Alteration of "Programmed Death Ligand" Promotes Cancer Metastasis
      Alteration of "Programmed Death Ligand" Promotes Cancer Metastasis
      There’s a protein that signals the immune system not to kill certain cells. This action could be preventing autoim ...
      Written By: Kara Marker
      3 1
      JUN 03, 2016
      Genetics & Genomics
      For the First Time: CRISPR for RNA
      For the First Time: CRISPR for RNA
      For the first time since 2007 when scientists were just beginning to understand the DNA manipulation capabilities of CRI ...
      Written By: Kara Marker
      4 3
      MAY 24, 2016
      Neuroscience
      New Technique to See Proteins in the Brain
      New Technique to See Proteins in the Brain
      At the Max Planck Florida Institute of Neuroscience (MPFIN), researchers are looking at a a method used to repair DNA in ...
      Written By: Brenda Kelley Kim
      4
      MAY 10, 2016
      Cell & Molecular Biology
      CRISPR/Cas9 Can Now Be Used to Track RNA In Vivo
      CRISPR/Cas9 Can Now Be Used to Track RNA In Vivo
      Since the development of the gene-editing tool CRISPR/Cas9, researchers have found many ways to both improve and vary th ...
      Written By: Carmen Leitch
      3
      APR 22, 2016
      Cell & Molecular Biology
      ‘Honeycomb' for gene transfer kills fewer cells
      ‘Honeycomb' for gene transfer kills fewer cells
      Scientists have created a new and highly efficient method for gene transfer. The technique, which involves culturing and ...
      Written By: Futurity (futurity.org)
      5
      MAR 14, 2016
      Clinical & Molecular DX
      Procedure Allows Kidney Transplant from Any Donor
      Procedure Allows Kidney Transplant from Any Donor
      Johns Hopkins researchers found a new way to transplant kidney organs from any donor – regardless of compatibility ...
      Written By: Xuan Pham
      10
      MAR 11, 2016
      Genetics & Genomics
      Improved CRISPR System Reads Induced Pluripotent Stem Cell Genome For the First Time
      Improved CRISPR System Reads Induced Pluripotent Stem Cell Genome For the First Time
      With an enhanced form of the CRISPR-Cas9 system, scientists were able to read the genome of induced pluripotent stem cel ...
      Written By: Kara Marker
      5
    DEC 08, 2016
    Cell & Molecular Biology
    Natural Off-Switch for CRISPR/Cas9 Identified
    Natural Off-Switch for CRISPR/Cas9 Identified
    The CRISPR/Cas9 genome-editing tool set off a revolution in biomedicine. Natural features of bacterial immunity were uti ...
    Written By: Carmen Leitch
    2
    NOV 30, 2016
    Cell & Molecular Biology
    Allen Institute Announces Public Release of Fluorescent Stem Cell Lines
    Allen Institute Announces Public Release of Fluorescent Stem Cell Lines
    The Allen Institute for Cell Science was founded by a contribution by Paul G. Allen, a cofounder of Microsoft, in 2014. ...
    Written By: Carmen Leitch
    2
    NOV 12, 2016
    Videos
    Towards a Cure for Sickle Cell Anemia Through CRISPR
    Towards a Cure for Sickle Cell Anemia Through CRISPR
    The CRISPR/Cas9 genome technique has paved the way for the development of many biological advances not only in research, ...
    Written By: Carmen Leitch
    1
    OCT 17, 2016
    Immunology
    One Enzyme and the Innate Immune Response
    One Enzyme and the Innate Immune Response
    The innate immune system helps an infected cell in one of two ways: calling the troops to bring in effector immune cells ...
    Written By: Kara Marker
    4
    OCT 04, 2016
    Microbiology
    New Details on the Bacterial Immune System, CRISPR/Cas, Revealed
    New Details on the Bacterial Immune System, CRISPR/Cas, Revealed
    The CRISPR/Cas9 gene editing system was developed in 2014 and has since had a huge impact on research in molecular biolo ...
    Written By: Carmen Leitch
    3
     
     
  • SEP 20, 2016
    Immunology
    This is how norovirus invades cells to make us sick
    This is how norovirus invades cells to make us sick
    Norovirus is the most common viral cause of diarrhea worldwide, but because of an inability to grow it in a lab, scienti ...
    Written By: Futurity (futurity.org)
    4
    SEP 16, 2016
    Videos
    CRISPR-Cas9 for Genetically Modified Humans?
    CRISPR-Cas9 for Genetically Modified Humans?
    Science portrayed in movies is, unsurprisingly, usually farfetched and largely separated from reality. However unrealist ...
    Written By: Kara Marker
    3
    SEP 13, 2016
    Microbiology
    Toxoplasma Genome Screen Reveals Parasitic Infection Mechanism
    Toxoplasma Genome Screen Reveals Parasitic Infection Mechanism
    After performing the first genome wide screen of Apicomplexa, researchers have identified a potential mechanism for the ...
    Written By: Carmen Leitch
    3
    AUG 31, 2016
    Cell & Molecular Biology
    New Genome Editing Technique Does not cut DNA
    New Genome Editing Technique Does not cut DNA
    Researchers have developed a genome editing technique that does not require DNA to be cleaved. Called Target-AID, the te ...
    Written By: Carmen Leitch
    4
    AUG 22, 2016
    Cell & Molecular Biology
    Cutting Edge Techniques Yield Potential Treatment for Rare Genetic Disease
    Cutting Edge Techniques Yield Potential Treatment for Rare Genetic Disease
    A research team led by Christopher J. Lengner of the University of Pennsylvania School of Veterinary Medicine and Brad J ...
    Written By: Carmen Leitch
    2
     
     
  • JUL 13, 2016
    Health & Medicine
    Tendon, Heal Thyself!
    Tendon, Heal Thyself!
    LA JOLLA, CA – July 13, 2016 – With the Rio Olympics just weeks away, many are wondering how Jamaican sprint ...
    Written By: The Scripps Research Institute (TSRI)
    3
    JUN 24, 2016
    Cancer
    An Integrated Approach to Find Drug Targets in Rare Cancers
    An Integrated Approach to Find Drug Targets in Rare Cancers
    Rare cancers account for about 25% of cancer in adults and about 10% of pediatric cancer cases. Unfortunately, prognosis ...
    Written By: Cassidy Reich
    2
    JUN 23, 2016
    Cell & Molecular Biology
    NIH Approves Human CRISPR Trial Funded by Sean Parker
    NIH Approves Human CRISPR Trial Funded by Sean Parker
    The US government panel that evaluates gene therapy trials, the National Institute of Health’s Recombinant DNA Res ...
    Written By: Carmen Leitch
    4
    JUN 20, 2016
    Microbiology
    A Proposal: Replace lab Essential E.coli With Fast-Growing Bacteria
    A Proposal: Replace lab Essential E.coli With Fast-Growing Bacteria
    A team of researchers at Harvard has made a revolutionary proposition to the world of molecular biology. They suggest th ...
    Written By: Carmen Leitch
    3
    JUN 17, 2016
    Cell & Molecular Biology
    Federal Safety Board to Consider First Use of CRISPR on Human
    Federal Safety Board to Consider First Use of CRISPR on Human
    A trial of the CRISPR/Cas9 gene editing technology has been proposed for use in a human patient. The National Institute ...
    Written By: Carmen Leitch
    1
     
     
  • JUN 13, 2016
    Cell & Molecular Biology
    Gene Drive Technology Gets Prudent Stamp of Approval
    Gene Drive Technology Gets Prudent Stamp of Approval
    Gene drive is a term used to describe the preferential dissemination of some versions of a gene to future generations.&n ...
    Written By: Carmen Leitch
    3
    JUN 10, 2016
    Genetics & Genomics
    CRISPR-Cpf1 Increases Efficiency of Genome Editing
    CRISPR-Cpf1 Increases Efficiency of Genome Editing
    CRISPR-Cas9 is the discovery that took the scientific community by storm, the technology of the century. In a new study ...
    Written By: Kara Marker
    1
    JUN 08, 2016
    Immunology
    Alteration of "Programmed Death Ligand" Promotes Cancer Metastasis
    Alteration of "Programmed Death Ligand" Promotes Cancer Metastasis
    There’s a protein that signals the immune system not to kill certain cells. This action could be preventing autoim ...
    Written By: Kara Marker
    3 1
    JUN 03, 2016
    Genetics & Genomics
    For the First Time: CRISPR for RNA
    For the First Time: CRISPR for RNA
    For the first time since 2007 when scientists were just beginning to understand the DNA manipulation capabilities of CRI ...
    Written By: Kara Marker
    4 3
    MAY 24, 2016
    Neuroscience
    New Technique to See Proteins in the Brain
    New Technique to See Proteins in the Brain
    At the Max Planck Florida Institute of Neuroscience (MPFIN), researchers are looking at a a method used to repair DNA in ...
    Written By: Brenda Kelley Kim
    4
     
     
  • MAY 10, 2016
    Cell & Molecular Biology
    CRISPR/Cas9 Can Now Be Used to Track RNA In Vivo
    CRISPR/Cas9 Can Now Be Used to Track RNA In Vivo
    Since the development of the gene-editing tool CRISPR/Cas9, researchers have found many ways to both improve and vary th ...
    Written By: Carmen Leitch
    3
    APR 22, 2016
    Cell & Molecular Biology
    ‘Honeycomb' for gene transfer kills fewer cells
    ‘Honeycomb' for gene transfer kills fewer cells
    Scientists have created a new and highly efficient method for gene transfer. The technique, which involves culturing and ...
    Written By: Futurity (futurity.org)
    5
    MAR 14, 2016
    Clinical & Molecular DX
    Procedure Allows Kidney Transplant from Any Donor
    Procedure Allows Kidney Transplant from Any Donor
    Johns Hopkins researchers found a new way to transplant kidney organs from any donor – regardless of compatibility ...
    Written By: Xuan Pham
    10
    MAR 11, 2016
    Genetics & Genomics
    Improved CRISPR System Reads Induced Pluripotent Stem Cell Genome For the First Time
    Improved CRISPR System Reads Induced Pluripotent Stem Cell Genome For the First Time
    With an enhanced form of the CRISPR-Cas9 system, scientists were able to read the genome of induced pluripotent stem cel ...
    Written By: Kara Marker
    5
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