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    DNA Damage

    DNA Damage: is an alteration in the chemical structure of DNA, such as a break in a strand of DNA, a base missing from the backbone of DNA, or a chemically changed base such as 8-OHdG. DNA damage can occur naturally or via environmental factors.

    Webinars

    • JAN 23, 2024 | 11:00 AM
      Maximizing the Potential of 3D Organoid Research with Automated Isolation
      Maximizing the Potential of 3D Organoid Research with Automated...
      The study of 3D organoids has transformed biomedical research, offering a more accurate representation of in vivo conditions. Maximizing the potential of 3D organoid research requires advanc...
      Speaker: Andris Abramenkovs
      Presented at: The Future of Biomedicine: Reproducible Advanced Cell Systems and Translational Insights
      3
      DEC 07, 2022 | 9:00 AM
      Gibco Cell Culture Heroes: 60th Anniversary Edition
      Gibco Cell Culture Heroes: 60th Anniversary Edition
      Date: December 07, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) Join us for an exciting live panel webinar, as we celebrate the 60th anniversary of Gibco Cell Culture. The panelists...
      Speaker: Jessica Hess , Rukia Henry , Ernesto Goulart , Ameet Chimote, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      20
      JUL 26, 2022 | 9:00 AM
      Applications in Cancer Research: RNA Isolation from Organoids and Spheroids
      Applications in Cancer Research: RNA Isolation from Organoids...
      Date: July 26, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Organoids and spheroids are increasingly being used in many research applications, including drug discovery, toxicology,...
      Speaker: Laura Chapman , Anupriya Gupta , Jay Bhandari
      Sponsored By: Thermo Fisher Scientific
      24
      JUN 30, 2022 | 9:00 AM
      The PCR Advantage: How the Biomark™ HD System Enhances the TruGraf® Gene Expression Test for Kidney Rejection
      The PCR Advantage: How the Biomark™ HD System Enhances the TruGraf®...
      Date: June 30, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Subclinical acute rejection (SubAR) is a significant risk for kidney transplant recipients, affecting 1 in 4 patients. Ea...
      Speaker: Juston Weems, Ph.D.
      Sponsored By: Standard BioTools
      8
      MAY 24, 2022 | 11:00 AM
      Next-Generation Sequencing (NGS) Assessment of Homologous Recombination Deficiency (HRD): Expanding NGS Data to View Events Associated with Genomic Instability
      Next-Generation Sequencing (NGS) Assessment of Homologous Recombination...
      Date: May 24, 2022 Time: 11:00am (PDT), 2:00pm (EDT), 7:00pm (CEST) NGS tumor profiling has become the mainstay of modern cancer therapy. Several NCCN-guided and FDA-approved therapies are c...
      Speaker: Dr. Christopher Lum, M.D. , Zan Halford, M.S. SMB(ASCP)CM,
      Sponsored By: BioDiscovery, A Bionano Genomics Company
      18
      MAR 22, 2022 | 7:00 AM
      Spatio-temporal characterization and quantification of DNA replication events by molecular combing
      Spatio-temporal characterization and quantification of DNA replication...
      Date: March 22, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) DNA replication happens at the very early stage of cell development, at such early stages of development...
      Speaker: Cyndie Forestier
      Sponsored By: Genomic Vision
      7
      SEP 29, 2021 | 11:59 PM
      Nanoparticle Based Delivery of Gene Editing Enzymes
      Nanoparticle Based Delivery of Gene Editing Enzymes
      Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
      Speaker: Niren Murthy, PhD
      Presented at: CRISPR Virtual Event Series 2021
      2 2
      SEP 17, 2021 | 12:00 PM
      Developing better techniques for 3D culture and analysis.
      Developing better techniques for 3D culture and analysis.
      Date: September 16, 2021 Time: 9:00pm (PDT), 12:00am (EDT) 3D cellular models like organoids and spheroids offer an opportunity to better understand complex biology in a physiologically rele...
      Speaker: Edwin Golez, M.S. , Bhaskar Mandavilli
      Sponsored By: Thermo Fisher Scientific/Gibco
      10 2
      DEC 03, 2020 | 3:00 PM
      Novel SARS-Cov-2 Neutralization Antibody test, performance and applications
      Novel SARS-Cov-2 Neutralization Antibody test, performance and...
      The presentation will provide a review of major emerging zoonotic virus outbreaks from Hendra virus in 1994 in Australia to SARS-CoV-2 in China 2019 and our latest findings on bat biology an...
      Speaker: Roumen Bogoev, MSc
      Presented at: Coronavirus Series
      Sponsored By: GenScript
      3
      NOV 12, 2020 | 1:30 PM
      Covid-19 Testing and the role of Antigen assays today and moving forward
      Covid-19 Testing and the role of Antigen assays today and moving...
      Today's presentation will cover the following topics from the perspective of a NYC based Laboratory: What have we learned year to date about CoV-2 and specifically how diagnostic testing...
      Speaker: Vincent Streva, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      Sponsored By: Diasorin
      1
      OCT 21, 2020 | 9:25 PM
      The role of PARPis and HRD testing in advanced ovarian cancer
      The role of PARPis and HRD testing in advanced ovarian cancer
      High grade serous ovarian cancer is characterized by genomic instability, with ~50% of advanced tumors harboring homologous recombination repair (HRR) pathway deficiency (HRD). HRD results i...
      Speaker: Natalie Ngoi, MBBS, MMed, MRCP
      Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
      0
      OCT 21, 2020 | 9:25 PM
      The role of PARPis and HRD testing in advanced ovarian cancer
      The role of PARPis and HRD testing in advanced ovarian cancer
      High grade serous ovarian cancer is characterized by genomic instability, with ~50% of advanced tumors harboring homologous recombination repair (HRR) pathway deficiency (HRD). HRD results i...
      Speaker: Natalie Ngoi, MBBS, MMed, MRCP
      Presented at: OncomineWorld Autumn: A virtual NGS education meeting
      1
      SEP 30, 2020 | 12:00 PM
      Efficient Generation of Gene-edited Mouse Models and Cell Lines Using Synthetic sgRNA
      Efficient Generation of Gene-edited Mouse Models and Cell Lines...
      The CRISPR/Cas genome editing system has revolutionized nearly every aspect of the life science industry. Until recently, the most used formats for this technology have been plasmids, mRNA,...
      Speaker: Gurpreet Balrey, PhD , Peter Romanienko, PhD
      Presented at: CRISPR Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      4
      SEP 30, 2020 | 12:00 AM
      In vivo delivery of Cas9 ribonucleoprotein and donor DNA with gold nanoparticles
      In vivo delivery of Cas9 ribonucleoprotein and donor DNA with...
      Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
      Speaker: Niren Murthy
      Presented at: CRISPR Virtual Event Series 2020
      4
      SEP 17, 2020 | 4:30 PM
      Ultra-fast one-step RT-PCR protocol for the detection of SARS-CoV-2
      Ultra-fast one-step RT-PCR protocol for the detection of SARS-CoV-2
      The COVID-19 pandemic has resulted in demand for population scale pathogen screening. The most sensitive and reliable method for detecting SARS-CoV-2 remains reverse transcription PCR (RT-PC...
      Speaker: Brian McNally, PhD
      Presented at: Coronavirus Series
      3
      SEP 10, 2020 | 7:30 AM
      Keynote Presentation: Discovery of a gene-microbiome interaction in lung cancer: lessons learned and future directions
      Keynote Presentation: Discovery of a gene-microbiome interaction...
      The selective pressure placed on the resident microbiota by local changes in the host environment – DNA damage, chronic inflammation, metabolic shifts, barrier damage, reduced immunosu...
      Speaker: K. Leigh Greathouse, PhD, MPH, MS, RD
      Presented at: Microbiology Week Virtual Event Series 2020
      3
      AUG 06, 2020 | 12:00 AM
      Causes and consequences of rapid cancer cell adaptation to therapeutic drugs
      Causes and consequences of rapid cancer cell adaptation to therapeutic...
      Despite the increasing number of effective anti-cancer therapies, successful treatment is limited by the development of drug resistance. While the contribution of genetic factors to drug res...
      Speaker: Sabrina Spencer, PhD
      Presented at: 2020 Beckman Symposium
      1
      JUN 17, 2020 | 12:00 PM
      Luminex®: Flexible Solutions for SARS-CoV-2 Detection
      Luminex®: Flexible Solutions for SARS-CoV-2 Detection
      Join us and hear from two Luminex® experts on our flexible solutions for molecular diagnostics. Dr. Sherry Dunbar and Dr. Aaron Benfield will describe our NxTAG® bead-based nucleic a...
      Speaker: Aaron P. Benfield, PhD , Sherry A. Dunbar, PhD, MBA
      Presented at: Coronavirus Series
      Sponsored By: Luminex - A DiaSorin Company
      1
      JUN 17, 2020 | 6:00 AM
      Role of serology in the next phase of COVID-19 investigation and response
      Role of serology in the next phase of COVID-19 investigation and...
      With more than 6 million infections and more than 300,000 deaths (as of end of May 2020), the current COVID-19 pandemic has led to large scale lockdown around the world to prevent further sp...
      Speaker: Linfa Wang, PhD
      Presented at: Coronavirus Series
      Sponsored By: GenScript
      1
      JAN 23, 2020 | 9:00 AM
      A Workflow for Knock-in Genome Editing: Simplified
      A Workflow for Knock-in Genome Editing: Simplified
      DATE: January 23, 2020 TIME: 9:00am PST, 12:00pm EST...
      Speaker: Matthew Poling, PhD
      Sponsored By: Thermo Fisher Scientific
      17
      JAN 01, 2020 | 6:00 AM
      Uncovering the mechanism of stress-resistant DNA replication in cancer cells using a modern single-molecule technique
      Uncovering the mechanism of stress-resistant DNA replication in...
      Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
      Speaker: Chames Kermi, PhD, PharmD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      OCT 10, 2019 | 1:30 PM
      Precision oncology: Biomarkers for treatment selection in metastatic castration resistant prostate cancer
      Precision oncology: Biomarkers for treatment selection in metastatic...
      Metastatic castration resistant prostate cancer (mCRPC) refractory to secondary hormonal treatments such as enzalutamide or abiraterone acetate are the most lethal of prostate cancers. In thi...
      Speaker: Tian Zhang, MD, MHS
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      1
      OCT 01, 2019 | 8:00 AM
      Looking under the Hood and Getting Started with the Optima AUC
      Looking under the Hood and Getting Started with the Optima AUC
      DATE: October 1, 2019TIME: 8:00am PTIn the webinar, Introduction to Characterization of Biomolecules Using Analytical Ultracentrifugation, we discussed the fundamentals of analytical...
      Speaker: Akash Bhattacharya, PhD , Ross VerHeul
      Sponsored By: Beckman Coulter Life Sciences
      4
      SEP 27, 2019 | 9:00 AM
      Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
      Investigating how Tpz-1 may be used as a novel therapeutic agent...
      DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
      Speaker: Jessica Hess
      Sponsored By: Thermo Fisher Scientific/Gibco
      5
    JAN 23, 2024 | 11:00 AM
    Maximizing the Potential of 3D Organoid Research with Automated Isolation
    Maximizing the Potential of 3D Organoid Research with Automated...
    The study of 3D organoids has transformed biomedical research, offering a more accurate representation of in vivo conditions. Maximizing the potential of 3D organoid research requires advanc...
    Speaker: Andris Abramenkovs
    Presented at: The Future of Biomedicine: Reproducible Advanced Cell Systems and Translational Insights
    3
    DEC 07, 2022 | 9:00 AM
    Gibco Cell Culture Heroes: 60th Anniversary Edition
    Gibco Cell Culture Heroes: 60th Anniversary Edition
    Date: December 07, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) Join us for an exciting live panel webinar, as we celebrate the 60th anniversary of Gibco Cell Culture. The panelists...
    Speaker: Jessica Hess , Rukia Henry , Ernesto Goulart , Ameet Chimote, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    20
    JUL 26, 2022 | 9:00 AM
    Applications in Cancer Research: RNA Isolation from Organoids and Spheroids
    Applications in Cancer Research: RNA Isolation from Organoids...
    Date: July 26, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Organoids and spheroids are increasingly being used in many research applications, including drug discovery, toxicology,...
    Speaker: Laura Chapman , Anupriya Gupta , Jay Bhandari
    Sponsored By: Thermo Fisher Scientific
    24
    JUN 30, 2022 | 9:00 AM
    The PCR Advantage: How the Biomark™ HD System Enhances the TruGraf® Gene Expression Test for Kidney Rejection
    The PCR Advantage: How the Biomark™ HD System Enhances the TruGraf®...
    Date: June 30, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Subclinical acute rejection (SubAR) is a significant risk for kidney transplant recipients, affecting 1 in 4 patients. Ea...
    Speaker: Juston Weems, Ph.D.
    Sponsored By: Standard BioTools
    8
    MAY 24, 2022 | 11:00 AM
    Next-Generation Sequencing (NGS) Assessment of Homologous Recombination Deficiency (HRD): Expanding NGS Data to View Events Associated with Genomic Instability
    Next-Generation Sequencing (NGS) Assessment of Homologous Recombination...
    Date: May 24, 2022 Time: 11:00am (PDT), 2:00pm (EDT), 7:00pm (CEST) NGS tumor profiling has become the mainstay of modern cancer therapy. Several NCCN-guided and FDA-approved therapies are c...
    Speaker: Dr. Christopher Lum, M.D. , Zan Halford, M.S. SMB(ASCP)CM,
    Sponsored By: BioDiscovery, A Bionano Genomics Company
    18
     
     
  • MAR 22, 2022 | 7:00 AM
    Spatio-temporal characterization and quantification of DNA replication events by molecular combing
    Spatio-temporal characterization and quantification of DNA replication...
    Date: March 22, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) DNA replication happens at the very early stage of cell development, at such early stages of development...
    Speaker: Cyndie Forestier
    Sponsored By: Genomic Vision
    7
    SEP 29, 2021 | 11:59 PM
    Nanoparticle Based Delivery of Gene Editing Enzymes
    Nanoparticle Based Delivery of Gene Editing Enzymes
    Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
    Speaker: Niren Murthy, PhD
    Presented at: CRISPR Virtual Event Series 2021
    2 2
    SEP 17, 2021 | 12:00 PM
    Developing better techniques for 3D culture and analysis.
    Developing better techniques for 3D culture and analysis.
    Date: September 16, 2021 Time: 9:00pm (PDT), 12:00am (EDT) 3D cellular models like organoids and spheroids offer an opportunity to better understand complex biology in a physiologically rele...
    Speaker: Edwin Golez, M.S. , Bhaskar Mandavilli
    Sponsored By: Thermo Fisher Scientific/Gibco
    10 2
    DEC 03, 2020 | 3:00 PM
    Novel SARS-Cov-2 Neutralization Antibody test, performance and applications
    Novel SARS-Cov-2 Neutralization Antibody test, performance and...
    The presentation will provide a review of major emerging zoonotic virus outbreaks from Hendra virus in 1994 in Australia to SARS-CoV-2 in China 2019 and our latest findings on bat biology an...
    Speaker: Roumen Bogoev, MSc
    Presented at: Coronavirus Series
    Sponsored By: GenScript
    3
    NOV 12, 2020 | 1:30 PM
    Covid-19 Testing and the role of Antigen assays today and moving forward
    Covid-19 Testing and the role of Antigen assays today and moving...
    Today's presentation will cover the following topics from the perspective of a NYC based Laboratory: What have we learned year to date about CoV-2 and specifically how diagnostic testing...
    Speaker: Vincent Streva, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    Sponsored By: Diasorin
    1
     
     
  • OCT 21, 2020 | 9:25 PM
    The role of PARPis and HRD testing in advanced ovarian cancer
    The role of PARPis and HRD testing in advanced ovarian cancer
    High grade serous ovarian cancer is characterized by genomic instability, with ~50% of advanced tumors harboring homologous recombination repair (HRR) pathway deficiency (HRD). HRD results i...
    Speaker: Natalie Ngoi, MBBS, MMed, MRCP
    Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
    0
    OCT 21, 2020 | 9:25 PM
    The role of PARPis and HRD testing in advanced ovarian cancer
    The role of PARPis and HRD testing in advanced ovarian cancer
    High grade serous ovarian cancer is characterized by genomic instability, with ~50% of advanced tumors harboring homologous recombination repair (HRR) pathway deficiency (HRD). HRD results i...
    Speaker: Natalie Ngoi, MBBS, MMed, MRCP
    Presented at: OncomineWorld Autumn: A virtual NGS education meeting
    1
    SEP 30, 2020 | 12:00 PM
    Efficient Generation of Gene-edited Mouse Models and Cell Lines Using Synthetic sgRNA
    Efficient Generation of Gene-edited Mouse Models and Cell Lines...
    The CRISPR/Cas genome editing system has revolutionized nearly every aspect of the life science industry. Until recently, the most used formats for this technology have been plasmids, mRNA,...
    Speaker: Gurpreet Balrey, PhD , Peter Romanienko, PhD
    Presented at: CRISPR Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    4
    SEP 30, 2020 | 12:00 AM
    In vivo delivery of Cas9 ribonucleoprotein and donor DNA with gold nanoparticles
    In vivo delivery of Cas9 ribonucleoprotein and donor DNA with...
    Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
    Speaker: Niren Murthy
    Presented at: CRISPR Virtual Event Series 2020
    4
    SEP 17, 2020 | 4:30 PM
    Ultra-fast one-step RT-PCR protocol for the detection of SARS-CoV-2
    Ultra-fast one-step RT-PCR protocol for the detection of SARS-CoV-2
    The COVID-19 pandemic has resulted in demand for population scale pathogen screening. The most sensitive and reliable method for detecting SARS-CoV-2 remains reverse transcription PCR (RT-PC...
    Speaker: Brian McNally, PhD
    Presented at: Coronavirus Series
    3
     
     
  • SEP 10, 2020 | 7:30 AM
    Keynote Presentation: Discovery of a gene-microbiome interaction in lung cancer: lessons learned and future directions
    Keynote Presentation: Discovery of a gene-microbiome interaction...
    The selective pressure placed on the resident microbiota by local changes in the host environment – DNA damage, chronic inflammation, metabolic shifts, barrier damage, reduced immunosu...
    Speaker: K. Leigh Greathouse, PhD, MPH, MS, RD
    Presented at: Microbiology Week Virtual Event Series 2020
    3
    AUG 06, 2020 | 12:00 AM
    Causes and consequences of rapid cancer cell adaptation to therapeutic drugs
    Causes and consequences of rapid cancer cell adaptation to therapeutic...
    Despite the increasing number of effective anti-cancer therapies, successful treatment is limited by the development of drug resistance. While the contribution of genetic factors to drug res...
    Speaker: Sabrina Spencer, PhD
    Presented at: 2020 Beckman Symposium
    1
    JUN 17, 2020 | 12:00 PM
    Luminex®: Flexible Solutions for SARS-CoV-2 Detection
    Luminex®: Flexible Solutions for SARS-CoV-2 Detection
    Join us and hear from two Luminex® experts on our flexible solutions for molecular diagnostics. Dr. Sherry Dunbar and Dr. Aaron Benfield will describe our NxTAG® bead-based nucleic a...
    Speaker: Aaron P. Benfield, PhD , Sherry A. Dunbar, PhD, MBA
    Presented at: Coronavirus Series
    Sponsored By: Luminex - A DiaSorin Company
    1
    JUN 17, 2020 | 6:00 AM
    Role of serology in the next phase of COVID-19 investigation and response
    Role of serology in the next phase of COVID-19 investigation and...
    With more than 6 million infections and more than 300,000 deaths (as of end of May 2020), the current COVID-19 pandemic has led to large scale lockdown around the world to prevent further sp...
    Speaker: Linfa Wang, PhD
    Presented at: Coronavirus Series
    Sponsored By: GenScript
    1
    JAN 23, 2020 | 9:00 AM
    A Workflow for Knock-in Genome Editing: Simplified
    A Workflow for Knock-in Genome Editing: Simplified
    DATE: January 23, 2020 TIME: 9:00am PST, 12:00pm EST...
    Speaker: Matthew Poling, PhD
    Sponsored By: Thermo Fisher Scientific
    17
     
     
  • JAN 01, 2020 | 6:00 AM
    Uncovering the mechanism of stress-resistant DNA replication in cancer cells using a modern single-molecule technique
    Uncovering the mechanism of stress-resistant DNA replication in...
    Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
    Speaker: Chames Kermi, PhD, PharmD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    OCT 10, 2019 | 1:30 PM
    Precision oncology: Biomarkers for treatment selection in metastatic castration resistant prostate cancer
    Precision oncology: Biomarkers for treatment selection in metastatic...
    Metastatic castration resistant prostate cancer (mCRPC) refractory to secondary hormonal treatments such as enzalutamide or abiraterone acetate are the most lethal of prostate cancers. In thi...
    Speaker: Tian Zhang, MD, MHS
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    1
    OCT 01, 2019 | 8:00 AM
    Looking under the Hood and Getting Started with the Optima AUC
    Looking under the Hood and Getting Started with the Optima AUC
    DATE: October 1, 2019TIME: 8:00am PTIn the webinar, Introduction to Characterization of Biomolecules Using Analytical Ultracentrifugation, we discussed the fundamentals of analytical...
    Speaker: Akash Bhattacharya, PhD , Ross VerHeul
    Sponsored By: Beckman Coulter Life Sciences
    4
    SEP 27, 2019 | 9:00 AM
    Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
    Investigating how Tpz-1 may be used as a novel therapeutic agent...
    DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
    Speaker: Jessica Hess
    Sponsored By: Thermo Fisher Scientific/Gibco
    5
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