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    Enhancer

    An Enhancer is a small section of DNA that can be used to bind protein together in order to increase the probability that the transcription of a specific gene will develop. There are hundreds of thousands of Enhancers that can be found in Prokaryotic and Eukaryotic cells within the human genome. Enhancers are cis-regulatory elements, which regulate the transcription of nearby genes and are an essential part of genetic regulatory networks.

    Webinars

    • NOV 05, 2020 | 12:00 AM
      Stigma and Substance Use: Evidence and Myths
      Stigma and Substance Use: Evidence and Myths
      Learning Objectives: 1. Discuss the disease state model of substance use disorder 2. Discuss the evidence surrounding common misconceptions regarding substance use disorder...
      Speaker: Thomas S. Franko, PharmD, BCACP
      Presented at: Opioid Crisis Virtual Event Series 2020
      2
      NOV 04, 2020 | 11:00 AM
      Developing flow-based analytical methods for gene-edited CAR-T programs: How to ensure an efficient transition from early research to clinical development
      Developing flow-based analytical methods for gene-edited CAR-T...
      DATE: November 4th, 2020 TIME: 11:00am PST As cell therapies become more complex, the need for robust analytical tools to characterize such products as they enter the clinic has increased in...
      Speaker: Aaron Edwards
      Sponsored By: Miltenyi Biotec
      6
      OCT 27, 2020 | 8:00 AM
      Lyophilization-Changing the Game for Molecular Diagnostics
      Lyophilization-Changing the Game for Molecular Diagnostics
      DATE: October 27th, 2020 TIME: 8:00am PT Molecular diagnostic assay development and design is no simple task, and several factors affect the performance and usability of a test. Diagnostic c...
      Speaker: Jerome Cabeau, MSc
      Sponsored By: Thermo Fisher Scientific
      11 2
      OCT 21, 2020 | 9:00 AM
      Keynote Presentation: Functional properties and digestibility of starch and flour under high-temperature cooking conditions
      Keynote Presentation: Functional properties and digestibility...
      Learning Objectives: 1. Understand the functionality and digestibility of starches at high heating temperatures as measured jointly by RVA 4800 and DSC 2. Acquire new knowledge on the behavi...
      Speaker: Dr. Yongfeng Ai
      Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2020
      1
      OCT 21, 2020 | 12:00 AM
      Overcoming the challenges of pesticide detection in food: Integrated workflow solutions to screen and confirm multi-residue contaminants
      Overcoming the challenges of pesticide detection in food: Integrated...
      Pesticides are routinely applied to crops to prevent or control pests and are therefore routinely tested for the presence of pesticide residues and to check for compliance with permitted Max...
      Speaker: Scott M. Peterman, PhD
      Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2020
      1
      OCT 09, 2020 | 8:00 AM
      The Expanding Role of Diagnostic Next Generation Sequencing (NGS) in the Clinical Microbiology Laboratory
      The Expanding Role of Diagnostic Next Generation Sequencing (NGS)...
      DATE: October 09, 2020 TIME: 08:00am PT Traditional culture techniques, as the primary diagnostic tool for infectious diseases, are coming under scrutiny for failing to universally detect in...
      Speaker: Joseph John, Jr., MD, FIDSA , Michael Schmidt, Ph.D. FAAM, FACD
      Sponsored By: MicroGenDX
      16
      OCT 08, 2020 | 4:30 PM
      Multiplex detection of oncogenic mutations using LNA-based assays on the QIAcuity digital PCR system
      Multiplex detection of oncogenic mutations using LNA-based assays...
      Multiplex detection of oncogenic mutations using LNA-based assays on the QIAcuity digital PCR system Digital PCR (dPCR) enables specific and sensitive detection of genetic alterations in onc...
      Speaker: Dr. Özlem Karalay
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: QIAGEN
      2
      OCT 08, 2020 | 10:30 AM
      Keynote Presentation: Principles of Effective Method Development in Pathobiology Research.
      Keynote Presentation: Principles of Effective Method Development...
      Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
      Speaker: Vivian Barry, MS
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: Roche Diagnostics
      1
      OCT 08, 2020 | 12:00 AM
      The biology of cancer disparities: an innate immunity story
      The biology of cancer disparities: an innate immunity story
      Cancer disparities among persons of African descent are driven by both biological and nonbiological factors. There is evidence in breast cancer that psychosocial factors (environment, socioe...
      Speaker: K. Sean Kimbro, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      1
      OCT 07, 2020 | 12:00 AM
      Oncogene additivity in the PI3K pathway in cancer
      Oncogene additivity in the PI3K pathway in cancer
      Activating mutations in PIK3CA are frequent in human breast cancer, and phosphoinositide 3-kinase alpha (PI3Kα) inhibitors have been approved for therapy. To characterize determinants...
      Speaker: Neil Vasan, MD, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      2
      OCT 06, 2020 | 10:00 AM
      The Art and Science of Haematology Morphology
      The Art and Science of Haematology Morphology
      DATE: October 6, 2020 TIME: 10:00am (PDT) The enumeration and analysis of blood cells with automated haematology analysers have significantly improved in recent years due to advances in cell...
      Speaker: Daniel Pelling, CSci, FIBMS, DFM
      Sponsored By: Abbott
      51 6
      OCT 01, 2020 | 10:00 AM
      Improvements to Bile Collection Studies in Rats
      Improvements to Bile Collection Studies in Rats
      Date: October 10, 2020 Time: 10:00am (PDT), 1:00pm (EDT) Rodent bile collection studies can be challenging. Not only do they require a technically difficult surgery, but there is also a lear...
      Speaker: Merryl Cramer , Brad Gien, BSc. CM , Gina Ma
      Sponsored By: SAI Infusion Technologies
      5 3
      SEP 30, 2020 | 6:00 AM
      Enhancing efficiency and specificity with improved CRISPR components and a new CRISPR analysis pipeline
      Enhancing efficiency and specificity with improved CRISPR components...
      Genome editing with an expanded CRISPR-Cas tool set increases the opportunity to make intentional, targeted changes in the genome. Furthermore, improved specificity of genome editing and abi...
      Speaker: Ashley Jacobi
      Presented at: CRISPR Virtual Event Series 2020
      Sponsored By: IDT
      2
      SEP 30, 2020 | 12:00 AM
      In vivo delivery of Cas9 ribonucleoprotein and donor DNA with gold nanoparticles
      In vivo delivery of Cas9 ribonucleoprotein and donor DNA with...
      Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
      Speaker: Niren Murthy
      Presented at: CRISPR Virtual Event Series 2020
      4
      SEP 23, 2020 | 1:30 PM
      Sponsor-led Round Table Discussion: Retail Analytics: How to Analyze Sales Data to Enhance Marketing and Operations
      Sponsor-led Round Table Discussion: Retail Analytics: How to Analyze...
      Use your sales data to understand how to maximize efficiency and revenue in your dispensary while also identifying consumer trends early on to put you way ahead of the retail curve....
      Speaker: Moderator: Stephanie Yarbrough
      Presented at: MJ Unpacked - Midwest
      1
      SEP 23, 2020 | 8:00 AM
      CAR T-Cell Immunotherapy of Solid Tumors - Learning from the Clinic and Lab in Parallel
      CAR T-Cell Immunotherapy of Solid Tumors - Learning from the Clinic...
      Date: Time: Over the last couple of years, it has become apparent that affinity-tuned CAR T cells display enhanced expansion and prolonged persistence in patients and that this strategy can...
      Speaker: John Maher, PhD , Rogier Reijmers, PhD
      LUMICKS
      9 1
      SEP 23, 2020 | 12:00 AM
      Clinical Scale production extracellular vesicles from various cell types in a cGMP compatible 3-D Capillary Bioreactor: from culture dish to 3-D capillary bioreactor
      Clinical Scale production extracellular vesicles from various...
      Extracellular vesicles (EV) from many cell types have demonstrated therapeutic potential against many different diseases. Inhibiting progress in this area is the capability to produce EVs in...
      Speaker: John J.S. Cadwell
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 23, 2020 | 12:00 AM
      Extracellular Vesicles and Chronic Kidney Disease
      Extracellular Vesicles and Chronic Kidney Disease
      Chronic kidney disease (CKD) is a major public health threat, affecting 11-15% of the U.S. population alone. Currently, there are no effective therapies to cure CKD. Drug therapies are not p...
      Speaker: Sargis Sedrakyan, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 17, 2020 | 12:00 PM
      Advanced NGS solutions for SARS-CoV-2 monitoring and insights
      Advanced NGS solutions for SARS-CoV-2 monitoring and insights
      Next-generation sequencing (NGS) is the primary technology used to identify genomic targets for vaccine development, detect emerging viral strains and monitor transmission patterns. Enhanced...
      Speaker: Cris Kinross
      Presented at: Coronavirus Series
      Sponsored By: Thermo Fisher Scientific
      1
      SEP 17, 2020 | 12:45 PM
      Stimuli-responsive Nanomaterials for Imaging Immunotherapy Response
      Stimuli-responsive Nanomaterials for Imaging Immunotherapy Response
      Immunotherapy such as immune checkpoint inhibitor antibodies have revolutionized the treatments for hard-to-treat cancers, with durable responses observed in clinics. However, the overall re...
      Speaker: Ashish Kulkarni, PhD
      Presented at: 7th Annual Conference: SBI2 High Content
      2
      SEP 10, 2020 | 12:00 AM
      Host responses to SARS-CoV-2
      Host responses to SARS-CoV-2
      The host response to infection is a critical determinant of virus pathogenicity. Emerging viruses require the host cellular machinery to replicate and successfully infect new hosts, and must...
      Speaker: Angela L. Rasmussen, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      2
      SEP 09, 2020 | 12:00 AM
      Understanding the role of virus-host interactions in tissue tropism of plant viruses
      Understanding the role of virus-host interactions in tissue tropism...
      To establish productive infection, plant viruses need to be able to efficiently invade and spread within a plant. Most viruses are introduced into a plant via the epidermal or mesophyll cell...
      Speaker: Svetlana Y. Folimonova
      Presented at: Microbiology Week Virtual Event Series 2020
      2
      SEP 09, 2020 | 12:00 AM
      Fc gamma receptor activation during viral infections: a double-edged sword
      Fc gamma receptor activation during viral infections: a double-edged...
      Over the last several decades, antibodies (Abs) have become a valuable weapon in the fight against viral infections, with several studies demonstrating the importance of both neutralizing an...
      Speaker: Raymond A. Alvarez, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 08, 2020 | 11:00 PM
      Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
      Deep mutational scanning of SARS-CoV-2 receptor binding domain...
      The receptor binding domain (RBD) of the SARS-CoV-2 spike glycoprotein mediates viral attachment to ACE2 receptor, and is a major determinant of host range and a dominant target of neutraliz...
      Speaker: Tyler Starr, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      4
    NOV 05, 2020 | 12:00 AM
    Stigma and Substance Use: Evidence and Myths
    Stigma and Substance Use: Evidence and Myths
    Learning Objectives: 1. Discuss the disease state model of substance use disorder 2. Discuss the evidence surrounding common misconceptions regarding substance use disorder...
    Speaker: Thomas S. Franko, PharmD, BCACP
    Presented at: Opioid Crisis Virtual Event Series 2020
    2
    NOV 04, 2020 | 11:00 AM
    Developing flow-based analytical methods for gene-edited CAR-T programs: How to ensure an efficient transition from early research to clinical development
    Developing flow-based analytical methods for gene-edited CAR-T...
    DATE: November 4th, 2020 TIME: 11:00am PST As cell therapies become more complex, the need for robust analytical tools to characterize such products as they enter the clinic has increased in...
    Speaker: Aaron Edwards
    Sponsored By: Miltenyi Biotec
    6
    OCT 27, 2020 | 8:00 AM
    Lyophilization-Changing the Game for Molecular Diagnostics
    Lyophilization-Changing the Game for Molecular Diagnostics
    DATE: October 27th, 2020 TIME: 8:00am PT Molecular diagnostic assay development and design is no simple task, and several factors affect the performance and usability of a test. Diagnostic c...
    Speaker: Jerome Cabeau, MSc
    Sponsored By: Thermo Fisher Scientific
    11 2
    OCT 21, 2020 | 9:00 AM
    Keynote Presentation: Functional properties and digestibility of starch and flour under high-temperature cooking conditions
    Keynote Presentation: Functional properties and digestibility...
    Learning Objectives: 1. Understand the functionality and digestibility of starches at high heating temperatures as measured jointly by RVA 4800 and DSC 2. Acquire new knowledge on the behavi...
    Speaker: Dr. Yongfeng Ai
    Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2020
    1
    OCT 21, 2020 | 12:00 AM
    Overcoming the challenges of pesticide detection in food: Integrated workflow solutions to screen and confirm multi-residue contaminants
    Overcoming the challenges of pesticide detection in food: Integrated...
    Pesticides are routinely applied to crops to prevent or control pests and are therefore routinely tested for the presence of pesticide residues and to check for compliance with permitted Max...
    Speaker: Scott M. Peterman, PhD
    Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2020
    1
     
     
  • OCT 09, 2020 | 8:00 AM
    The Expanding Role of Diagnostic Next Generation Sequencing (NGS) in the Clinical Microbiology Laboratory
    The Expanding Role of Diagnostic Next Generation Sequencing (NGS)...
    DATE: October 09, 2020 TIME: 08:00am PT Traditional culture techniques, as the primary diagnostic tool for infectious diseases, are coming under scrutiny for failing to universally detect in...
    Speaker: Joseph John, Jr., MD, FIDSA , Michael Schmidt, Ph.D. FAAM, FACD
    Sponsored By: MicroGenDX
    16
    OCT 08, 2020 | 4:30 PM
    Multiplex detection of oncogenic mutations using LNA-based assays on the QIAcuity digital PCR system
    Multiplex detection of oncogenic mutations using LNA-based assays...
    Multiplex detection of oncogenic mutations using LNA-based assays on the QIAcuity digital PCR system Digital PCR (dPCR) enables specific and sensitive detection of genetic alterations in onc...
    Speaker: Dr. Özlem Karalay
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: QIAGEN
    2
    OCT 08, 2020 | 10:30 AM
    Keynote Presentation: Principles of Effective Method Development in Pathobiology Research.
    Keynote Presentation: Principles of Effective Method Development...
    Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
    Speaker: Vivian Barry, MS
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: Roche Diagnostics
    1
    OCT 08, 2020 | 12:00 AM
    The biology of cancer disparities: an innate immunity story
    The biology of cancer disparities: an innate immunity story
    Cancer disparities among persons of African descent are driven by both biological and nonbiological factors. There is evidence in breast cancer that psychosocial factors (environment, socioe...
    Speaker: K. Sean Kimbro, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    1
    OCT 07, 2020 | 12:00 AM
    Oncogene additivity in the PI3K pathway in cancer
    Oncogene additivity in the PI3K pathway in cancer
    Activating mutations in PIK3CA are frequent in human breast cancer, and phosphoinositide 3-kinase alpha (PI3Kα) inhibitors have been approved for therapy. To characterize determinants...
    Speaker: Neil Vasan, MD, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    2
     
     
  • OCT 06, 2020 | 10:00 AM
    The Art and Science of Haematology Morphology
    The Art and Science of Haematology Morphology
    DATE: October 6, 2020 TIME: 10:00am (PDT) The enumeration and analysis of blood cells with automated haematology analysers have significantly improved in recent years due to advances in cell...
    Speaker: Daniel Pelling, CSci, FIBMS, DFM
    Sponsored By: Abbott
    51 6
    OCT 01, 2020 | 10:00 AM
    Improvements to Bile Collection Studies in Rats
    Improvements to Bile Collection Studies in Rats
    Date: October 10, 2020 Time: 10:00am (PDT), 1:00pm (EDT) Rodent bile collection studies can be challenging. Not only do they require a technically difficult surgery, but there is also a lear...
    Speaker: Merryl Cramer , Brad Gien, BSc. CM , Gina Ma
    Sponsored By: SAI Infusion Technologies
    5 3
    SEP 30, 2020 | 6:00 AM
    Enhancing efficiency and specificity with improved CRISPR components and a new CRISPR analysis pipeline
    Enhancing efficiency and specificity with improved CRISPR components...
    Genome editing with an expanded CRISPR-Cas tool set increases the opportunity to make intentional, targeted changes in the genome. Furthermore, improved specificity of genome editing and abi...
    Speaker: Ashley Jacobi
    Presented at: CRISPR Virtual Event Series 2020
    Sponsored By: IDT
    2
    SEP 30, 2020 | 12:00 AM
    In vivo delivery of Cas9 ribonucleoprotein and donor DNA with gold nanoparticles
    In vivo delivery of Cas9 ribonucleoprotein and donor DNA with...
    Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
    Speaker: Niren Murthy
    Presented at: CRISPR Virtual Event Series 2020
    4
    SEP 23, 2020 | 1:30 PM
    Sponsor-led Round Table Discussion: Retail Analytics: How to Analyze Sales Data to Enhance Marketing and Operations
    Sponsor-led Round Table Discussion: Retail Analytics: How to Analyze...
    Use your sales data to understand how to maximize efficiency and revenue in your dispensary while also identifying consumer trends early on to put you way ahead of the retail curve....
    Speaker: Moderator: Stephanie Yarbrough
    Presented at: MJ Unpacked - Midwest
    1
     
     
  • SEP 23, 2020 | 8:00 AM
    CAR T-Cell Immunotherapy of Solid Tumors - Learning from the Clinic and Lab in Parallel
    CAR T-Cell Immunotherapy of Solid Tumors - Learning from the Clinic...
    Date: Time: Over the last couple of years, it has become apparent that affinity-tuned CAR T cells display enhanced expansion and prolonged persistence in patients and that this strategy can...
    Speaker: John Maher, PhD , Rogier Reijmers, PhD
    LUMICKS
    9 1
    SEP 23, 2020 | 12:00 AM
    Clinical Scale production extracellular vesicles from various cell types in a cGMP compatible 3-D Capillary Bioreactor: from culture dish to 3-D capillary bioreactor
    Clinical Scale production extracellular vesicles from various...
    Extracellular vesicles (EV) from many cell types have demonstrated therapeutic potential against many different diseases. Inhibiting progress in this area is the capability to produce EVs in...
    Speaker: John J.S. Cadwell
    Presented at: Cell Biology Virtual Event Series 2020
    1
    SEP 23, 2020 | 12:00 AM
    Extracellular Vesicles and Chronic Kidney Disease
    Extracellular Vesicles and Chronic Kidney Disease
    Chronic kidney disease (CKD) is a major public health threat, affecting 11-15% of the U.S. population alone. Currently, there are no effective therapies to cure CKD. Drug therapies are not p...
    Speaker: Sargis Sedrakyan, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    1
    SEP 17, 2020 | 12:00 PM
    Advanced NGS solutions for SARS-CoV-2 monitoring and insights
    Advanced NGS solutions for SARS-CoV-2 monitoring and insights
    Next-generation sequencing (NGS) is the primary technology used to identify genomic targets for vaccine development, detect emerging viral strains and monitor transmission patterns. Enhanced...
    Speaker: Cris Kinross
    Presented at: Coronavirus Series
    Sponsored By: Thermo Fisher Scientific
    1
    SEP 17, 2020 | 12:45 PM
    Stimuli-responsive Nanomaterials for Imaging Immunotherapy Response
    Stimuli-responsive Nanomaterials for Imaging Immunotherapy Response
    Immunotherapy such as immune checkpoint inhibitor antibodies have revolutionized the treatments for hard-to-treat cancers, with durable responses observed in clinics. However, the overall re...
    Speaker: Ashish Kulkarni, PhD
    Presented at: 7th Annual Conference: SBI2 High Content
    2
     
     
  • SEP 10, 2020 | 12:00 AM
    Host responses to SARS-CoV-2
    Host responses to SARS-CoV-2
    The host response to infection is a critical determinant of virus pathogenicity. Emerging viruses require the host cellular machinery to replicate and successfully infect new hosts, and must...
    Speaker: Angela L. Rasmussen, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    2
    SEP 09, 2020 | 12:00 AM
    Understanding the role of virus-host interactions in tissue tropism of plant viruses
    Understanding the role of virus-host interactions in tissue tropism...
    To establish productive infection, plant viruses need to be able to efficiently invade and spread within a plant. Most viruses are introduced into a plant via the epidermal or mesophyll cell...
    Speaker: Svetlana Y. Folimonova
    Presented at: Microbiology Week Virtual Event Series 2020
    2
    SEP 09, 2020 | 12:00 AM
    Fc gamma receptor activation during viral infections: a double-edged sword
    Fc gamma receptor activation during viral infections: a double-edged...
    Over the last several decades, antibodies (Abs) have become a valuable weapon in the fight against viral infections, with several studies demonstrating the importance of both neutralizing an...
    Speaker: Raymond A. Alvarez, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 08, 2020 | 11:00 PM
    Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
    Deep mutational scanning of SARS-CoV-2 receptor binding domain...
    The receptor binding domain (RBD) of the SARS-CoV-2 spike glycoprotein mediates viral attachment to ACE2 receptor, and is a major determinant of host range and a dominant target of neutraliz...
    Speaker: Tyler Starr, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    4
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