An enzyme is a substance that acts as a catalyst in living organisms; they regulate and speed up the rate at which chemical reactions proceed.
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The CYP2D6 enzyme metabolizes approximately 25% of commonly used pharmaceuticals and is of intense pharmacogenetic interest. Polymorphisms in CYP2D6 can alter an individual’s response...
Learning Objectives: 1. Explain what is gene therapy is. 2. Explain what steps are involved for getting a gene therapy product to the clinic. 3. Discuss development and manufacturing process...
Date: March 29, 2022 Time: 09:00am (PDT), 12:00pm (EDT), 17:00 (GMT) Advances in molecular and immunodiagnostics are enabling a personalized, high-precision approach to health in many clin...
Date: February 24, 2021 Time: 10:00am (PST), 1:00pm (EST) One of the largest global public health crises is the rise of antimicrobial-resistant infections. Globally, over 700,000 people die...
Date: January 13, 2022 Time: 09:00am (PST), 12:00pm (EST) Recently, the Infectious Disease Society of America released guidance on how to approach treatment of infections caused by multidrug...
Date: December 9, 2021 Time: 9:00am (PDT), 12:00am (EDT) CRISPR editing has revolutionized plant breeding, and the MAD7 CRISPR nuclease developed by InscriptaTM is democratizing access to CR...
Date: December 08, 2021 Time: 7:00am (PDT), 10:00am (EDT) Successful bioprocessing is complex and depends on many factors. From the selection of the expression host, media composition, the p...
Date: December 7, 2021 Time: 9:00am (PST), 12:00pm (EST) The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than...
Date: November 08, 2021 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CET) Many enzymes form homomeric complexes comprised of subunits encoded by the same gene. Assembly into homomeric...
Date: October 28, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Loop-mediated isothermal amplification (LAMP) uses a stand-displacing DNA polymerase and four to six primers to rapidly amplify DNA a...
Date: October 14, 2021 Time: 7:00am (PDT), 10:00am (EDT) Heterologous protein expression in model organisms has many applications, including protein engineering, production of industrial enz...
Date: October 13, 2021 Time: 10:00am (PDT), 01:00pm (EDT) Clinically-relevant applications, such as somatic variant detection, continue to push the bounds...
Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
RNA plays important and diverse roles in biology, but molecular tools to manipulate and measure RNA are limited. We demonstrate that RNA-targeting CRISPR effector Cas13 and novel RNA targeti...