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    Follow

    Gene Regulation

    Gene Regulation is created by using mechanisms to inhibit or induce the expression of a gene product. Regulation of a gene can include: the binding of proteins to DNA elements in order to regulation of transcription, structural changes, chemical changes, or the translation of mRNA.

    Webinars

    • FEB 06, 2014 | 10:00 AM
      Social housing of non-human primates: can it become the norm internationally?
      Social housing of non-human primates: can it become the norm internationally?
      It is well documented that social housing is fundamental to good welfare for non-human primates (NHPs). Despite this, many laboratory NHPs around the world continue to be singly housed, thoug...
      Speaker: Mark Prescott, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
      FEB 06, 2014 | 9:00 AM
      Training and Competency Assessment
      Training and Competency Assessment
      The 2011 Guide for the Care and Use of Laboratory Animals has required that institutions place importance on assuring that staff working with animals are trained and competent to perform thei...
      Speaker: Mary Ann Vasbinder, DVM, ACLAM and Asheley Wathen, DVM, MPH, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
      FEB 06, 2014 | 9:00 AM
      C.E. CREDITS
      The newest animal facility at Cinvestav. Design & Features
      The newest animal facility at Cinvestav. Design & Features
      The new animal facility is designed to breed and house rodents with the best quality of macro and micro environment and house the maximum possible number of rodents per sf2. This new facilit...
      Speaker: Jorge Fernandez Hernandez, DVM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      20
      FEB 06, 2014 | 7:00 AM
      Barriers to analgesic use - assessing the potential interactions of analgesics and unalleviated pain on research outcomes
      Barriers to analgesic use - assessing the potential interactions...
      Regulations and guidelines governing the use of animals in research require minimization of pain and distress. However, pharmacologic treatments to prevent or alleviate pain can interfere wit...
      Speaker: Jennifer Lofgren, DVM, MS, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
      FEB 06, 2014 | 7:00 AM
      C.E. CREDITS
      Pain perception: the scientific evidence, assessment and alleviation of pain in fish
      Pain perception: the scientific evidence, assessment and alleviation...
      The question of pain in fish has been subject to much debate and, since fish are a popular experimental model globally and commercially important in fisheries, recreational angling and aquac...
      Speaker: Lynne U Sneddon, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      12
      FEB 05, 2014 | 7:00 PM
      Laws & Regulations Involving Laboratory Animal Industry in China
      Laws & Regulations Involving Laboratory Animal Industry in China
      The laboratory animal industry had expanded rapidly in China recently. It is critical to have a good basic understanding of the domestic laws and regulations involving laboratory animals if a...
      Speaker: Frank Lu, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      1
      FEB 05, 2014 | 5:00 PM
      C.E. CREDITS
      Veterinary treatment approaches to common clinical signs in toxicology setting
      Veterinary treatment approaches to common clinical signs in toxicology...
      This presentation mainly includes 4 sections, the first one: introduction for CFDA/FDA GLP Regulation and analysis the difference. The second one: introduction of the most important responsi...
      Speaker: Xueying Pan, MS, PhD Candidate
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      10
      FEB 05, 2014 | 11:00 AM
      Ensuring and Assessing Training and/or Qualifications of Personnel in Animal Care and Use Programs: The AAALAC Perspective
      Ensuring and Assessing Training and/or Qualifications of Personnel...
      All personnel involved in an animal care and use program are expected to have an appropriate level of education, training and/or qualifications to perform their duties as defined through laws...
      Speaker: John N Norton, D.V.M., PhD, Dipl, ABT, ACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      2
      OCT 16, 2013 | 1:00 PM
      C.E. CREDITS
      Investigating tissue specificity of cancer-causing germline mutations
      Investigating tissue specificity of cancer-causing germline mutations
      The remarkable diversity we see between different cell types in the human body is governed by the specificity attained through transcriptional and epigenetic regulatory programs. Cancer is a...
      Speaker: Jessica C. Mar, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      68
      OCT 16, 2013 | 11:00 AM
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, a...
      Speaker: Michael J Mann, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      58
      OCT 16, 2013 | 7:00 AM
      Metabolic reprogramming: links to the epigenome
      Metabolic reprogramming: links to the epigenome
      Cancer cells are characterized by major alterations in both cellular metabolism and epigenetic profiles. Current understanding of links between metabolism and chromatin in the context of can...
      Speaker: Kathryn E Wellen, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      108
      AUG 22, 2013 | 4:00 PM
      C.E. CREDITS
      Complexity of Mammalian Transcription
      Complexity of Mammalian Transcription
      The next generation sequencing technologies are profoundly influencing our way to study biology. We have previously developed cap-analysis gene expression (CAGE) to simultaneously mRNA/noncod...
      Speaker: Piero Carninci, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      50
      AUG 22, 2013 | 1:00 PM
      Dominant regulation of gene expression by microRNAs
      Dominant regulation of gene expression by microRNAs
      MicroRNAs are short non-coding cellular regulators of gene expression. Each microRNA controls the expression of a large set of genes, and microRNAs collectively, may regulate more than half o...
      Speaker: Noam Shomron, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      121
      AUG 22, 2013 | 12:00 PM
      C.E. CREDITS
      Exome Sequencing as a Diagnostic Tool
      Exome Sequencing as a Diagnostic Tool
      It is widely accepted that approximately 85% of known disease-causing DNA variants affect the exons and splice junctions, which is about 1% of the whole genome. As a result, Clinical Exome Se...
      Speaker: Pinar Bayrak-Toydemir, MD, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      66
      AUG 22, 2013 | 9:00 AM
      Next-Gen Sequencing: Driving the Transition from Genetics to Genomics
      Next-Gen Sequencing: Driving the Transition from Genetics to Genomics
      The rapid advancements in next generation sequencing have served the research market very well, delivering more and more sequence for less and less money. While these advancements are still b...
      Speaker: Shawn Baker, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      222
      AUG 22, 2013 | 7:00 AM
      C.E. CREDITS
      Metabolic reprogramming: links to the epigenome
      Metabolic reprogramming: links to the epigenome
      Cancer cells are characterized by major alterations in both cellular metabolism and epigenetic profiles. Current understanding of links between metabolism and chromatin in the context of canc...
      Speaker: Kathryn E Wellen, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      96
      AUG 21, 2013 | 4:00 PM
      C.E. CREDITS
      The hidden layer of RNA regulation in human development
      The hidden layer of RNA regulation in human development
      High throughput transcriptomic analyses have shown that most of the human genome is dynamically transcribed to produce an extraordinary range of overlapping and interlacing intronic, intergen...
      Speaker: John Mattick, PhD,AO, FAA, FRCPA
      Presented at: Genetics and Genomics Virtual Event Series 2013
      132
      AUG 21, 2013 | 3:00 PM
      C.E. CREDITS
      Investigating tissue specificity of cancer-causing germline mutations
      Investigating tissue specificity of cancer-causing germline mutations
      The remarkable diversity we see between different cell types in the human body is governed by the specificity attained through transcriptional and epigenetic regulatory programs. Cancer is a...
      Speaker: Jessica C. Mar, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      70
      AUG 21, 2013 | 3:00 PM
      C.E. CREDITS
      Evolution of Alu elements in long non-coding RNA and mRNA
      Evolution of Alu elements in long non-coding RNA and mRNA
      Long non-coding RNAs (lncRNA) are a novel class of RNA molecule that are emerging as important regulators of gene transcription and post-transcriptional events. lncRNAs have been shown to reg...
      Speaker: Daniel Caffrey, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      42
      AUG 21, 2013 | 1:00 PM
      C.E. CREDITS
      Codon optimization: new safety concerns for gene therapy and genetic vaccines
      Codon optimization: new safety concerns for gene therapy and genetic...
      Codon-optimization describes gene engineering approaches that use synonymous codon changes to increase protein production. It is used extensively for expressing recombinant protein drugs, gen...
      Speaker: Vincent P Mauro, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      86
      AUG 21, 2013 | 11:00 AM
      Panel Discussion: Meeting the Demand of Increased NGS Capacity with Automated TruSeq Stranded mRNA Library Preparation
      Panel Discussion: Meeting the Demand of Increased NGS Capacity...
      RNASeq has become the primary method for studying changes in gene expression in modern genomics research. By directly sequencing the various types of RNA molecules, including mRNA, ncRNA, an...
      Speaker: Alisa Jackson, Zach Smith, Mary Blair, Dave Delano
      Presented at: Genetics and Genomics Virtual Event Series 2013
      41
      MAY 30, 2013 | 9:00 AM
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
      Speaker: Michael J Mann, MD
      Presented at: Clinical Diagnostics Virtual Event Series 2013
      19
    FEB 06, 2014 | 10:00 AM
    Social housing of non-human primates: can it become the norm internationally?
    Social housing of non-human primates: can it become the norm internationally?
    It is well documented that social housing is fundamental to good welfare for non-human primates (NHPs). Despite this, many laboratory NHPs around the world continue to be singly housed, thoug...
    Speaker: Mark Prescott, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
    FEB 06, 2014 | 9:00 AM
    Training and Competency Assessment
    Training and Competency Assessment
    The 2011 Guide for the Care and Use of Laboratory Animals has required that institutions place importance on assuring that staff working with animals are trained and competent to perform thei...
    Speaker: Mary Ann Vasbinder, DVM, ACLAM and Asheley Wathen, DVM, MPH, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
    FEB 06, 2014 | 9:00 AM
    C.E. CREDITS
    The newest animal facility at Cinvestav. Design & Features
    The newest animal facility at Cinvestav. Design & Features
    The new animal facility is designed to breed and house rodents with the best quality of macro and micro environment and house the maximum possible number of rodents per sf2. This new facilit...
    Speaker: Jorge Fernandez Hernandez, DVM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    20
    FEB 06, 2014 | 7:00 AM
    Barriers to analgesic use - assessing the potential interactions of analgesics and unalleviated pain on research outcomes
    Barriers to analgesic use - assessing the potential interactions...
    Regulations and guidelines governing the use of animals in research require minimization of pain and distress. However, pharmacologic treatments to prevent or alleviate pain can interfere wit...
    Speaker: Jennifer Lofgren, DVM, MS, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
    FEB 06, 2014 | 7:00 AM
    C.E. CREDITS
    Pain perception: the scientific evidence, assessment and alleviation of pain in fish
    Pain perception: the scientific evidence, assessment and alleviation...
    The question of pain in fish has been subject to much debate and, since fish are a popular experimental model globally and commercially important in fisheries, recreational angling and aquac...
    Speaker: Lynne U Sneddon, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    12
     
     
  • FEB 05, 2014 | 7:00 PM
    Laws & Regulations Involving Laboratory Animal Industry in China
    Laws & Regulations Involving Laboratory Animal Industry in China
    The laboratory animal industry had expanded rapidly in China recently. It is critical to have a good basic understanding of the domestic laws and regulations involving laboratory animals if a...
    Speaker: Frank Lu, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    1
    FEB 05, 2014 | 5:00 PM
    C.E. CREDITS
    Veterinary treatment approaches to common clinical signs in toxicology setting
    Veterinary treatment approaches to common clinical signs in toxicology...
    This presentation mainly includes 4 sections, the first one: introduction for CFDA/FDA GLP Regulation and analysis the difference. The second one: introduction of the most important responsi...
    Speaker: Xueying Pan, MS, PhD Candidate
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    10
    FEB 05, 2014 | 11:00 AM
    Ensuring and Assessing Training and/or Qualifications of Personnel in Animal Care and Use Programs: The AAALAC Perspective
    Ensuring and Assessing Training and/or Qualifications of Personnel...
    All personnel involved in an animal care and use program are expected to have an appropriate level of education, training and/or qualifications to perform their duties as defined through laws...
    Speaker: John N Norton, D.V.M., PhD, Dipl, ABT, ACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    2
    OCT 16, 2013 | 1:00 PM
    C.E. CREDITS
    Investigating tissue specificity of cancer-causing germline mutations
    Investigating tissue specificity of cancer-causing germline mutations
    The remarkable diversity we see between different cell types in the human body is governed by the specificity attained through transcriptional and epigenetic regulatory programs. Cancer is a...
    Speaker: Jessica C. Mar, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    68
    OCT 16, 2013 | 11:00 AM
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, a...
    Speaker: Michael J Mann, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    58
     
     
  • OCT 16, 2013 | 7:00 AM
    Metabolic reprogramming: links to the epigenome
    Metabolic reprogramming: links to the epigenome
    Cancer cells are characterized by major alterations in both cellular metabolism and epigenetic profiles. Current understanding of links between metabolism and chromatin in the context of can...
    Speaker: Kathryn E Wellen, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    108
    AUG 22, 2013 | 4:00 PM
    C.E. CREDITS
    Complexity of Mammalian Transcription
    Complexity of Mammalian Transcription
    The next generation sequencing technologies are profoundly influencing our way to study biology. We have previously developed cap-analysis gene expression (CAGE) to simultaneously mRNA/noncod...
    Speaker: Piero Carninci, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    50
    AUG 22, 2013 | 1:00 PM
    Dominant regulation of gene expression by microRNAs
    Dominant regulation of gene expression by microRNAs
    MicroRNAs are short non-coding cellular regulators of gene expression. Each microRNA controls the expression of a large set of genes, and microRNAs collectively, may regulate more than half o...
    Speaker: Noam Shomron, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    121
    AUG 22, 2013 | 12:00 PM
    C.E. CREDITS
    Exome Sequencing as a Diagnostic Tool
    Exome Sequencing as a Diagnostic Tool
    It is widely accepted that approximately 85% of known disease-causing DNA variants affect the exons and splice junctions, which is about 1% of the whole genome. As a result, Clinical Exome Se...
    Speaker: Pinar Bayrak-Toydemir, MD, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    66
    AUG 22, 2013 | 9:00 AM
    Next-Gen Sequencing: Driving the Transition from Genetics to Genomics
    Next-Gen Sequencing: Driving the Transition from Genetics to Genomics
    The rapid advancements in next generation sequencing have served the research market very well, delivering more and more sequence for less and less money. While these advancements are still b...
    Speaker: Shawn Baker, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    222
     
     
  • AUG 22, 2013 | 7:00 AM
    C.E. CREDITS
    Metabolic reprogramming: links to the epigenome
    Metabolic reprogramming: links to the epigenome
    Cancer cells are characterized by major alterations in both cellular metabolism and epigenetic profiles. Current understanding of links between metabolism and chromatin in the context of canc...
    Speaker: Kathryn E Wellen, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    96
    AUG 21, 2013 | 4:00 PM
    C.E. CREDITS
    The hidden layer of RNA regulation in human development
    The hidden layer of RNA regulation in human development
    High throughput transcriptomic analyses have shown that most of the human genome is dynamically transcribed to produce an extraordinary range of overlapping and interlacing intronic, intergen...
    Speaker: John Mattick, PhD,AO, FAA, FRCPA
    Presented at: Genetics and Genomics Virtual Event Series 2013
    132
    AUG 21, 2013 | 3:00 PM
    C.E. CREDITS
    Investigating tissue specificity of cancer-causing germline mutations
    Investigating tissue specificity of cancer-causing germline mutations
    The remarkable diversity we see between different cell types in the human body is governed by the specificity attained through transcriptional and epigenetic regulatory programs. Cancer is a...
    Speaker: Jessica C. Mar, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    70
    AUG 21, 2013 | 3:00 PM
    C.E. CREDITS
    Evolution of Alu elements in long non-coding RNA and mRNA
    Evolution of Alu elements in long non-coding RNA and mRNA
    Long non-coding RNAs (lncRNA) are a novel class of RNA molecule that are emerging as important regulators of gene transcription and post-transcriptional events. lncRNAs have been shown to reg...
    Speaker: Daniel Caffrey, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    42
    AUG 21, 2013 | 1:00 PM
    C.E. CREDITS
    Codon optimization: new safety concerns for gene therapy and genetic vaccines
    Codon optimization: new safety concerns for gene therapy and genetic...
    Codon-optimization describes gene engineering approaches that use synonymous codon changes to increase protein production. It is used extensively for expressing recombinant protein drugs, gen...
    Speaker: Vincent P Mauro, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    86
     
     
  • AUG 21, 2013 | 11:00 AM
    Panel Discussion: Meeting the Demand of Increased NGS Capacity with Automated TruSeq Stranded mRNA Library Preparation
    Panel Discussion: Meeting the Demand of Increased NGS Capacity...
    RNASeq has become the primary method for studying changes in gene expression in modern genomics research. By directly sequencing the various types of RNA molecules, including mRNA, ncRNA, an...
    Speaker: Alisa Jackson, Zach Smith, Mary Blair, Dave Delano
    Presented at: Genetics and Genomics Virtual Event Series 2013
    41
    MAY 30, 2013 | 9:00 AM
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
    Speaker: Michael J Mann, MD
    Presented at: Clinical Diagnostics Virtual Event Series 2013
    19
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