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    Mechanics

    Mechanics: an area of science concerned with the behaviour of physical bodies when subjected to forces or displacements, and the subsequent effects of the bodies on their environment. During the early modern period, scientists such as Galileo, Kepler, and Newton, laid the foundation for what is now known as classical mechanics. It is a branch of classical physics that deals with particles that are either at rest or are moving with velocities significantly less than the speed of light. It can also be defined as a branch of science which deals with the motion of and forces on objects.

    Webinars

    • JAN 01, 2020 | 6:00 AM
      Uncovering the mechanism of stress-resistant DNA replication in cancer cells using a modern single-molecule technique
      Uncovering the mechanism of stress-resistant DNA replication in...
      Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
      Speaker: Chames Kermi, PhD, PharmD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      DEC 17, 2019 | 8:00 AM
      Single-Cell Phosphoprotein Analysis with CyTOF: From Training to Immuno-Oncology Clinical Research
      Single-Cell Phosphoprotein Analysis with CyTOF: From Training...
      DATE: December 17, 2019TIME: 8:00am PSTMass cytometry instruments simultaneously measure >50 cellular features, with a typical experiment including millions of cells. Dysregulated...
      Speaker: Jonathan Irish, PhD , Caroline E. Roe, BS
      Sponsored By: Standard BioTools
      7 2
      DEC 05, 2019 | 5:00 AM
      The clinical implications of high sensitive assays for HBsAg
      The clinical implications of high sensitive assays for HBsAg
      DATE: December 5, 2019TIME: 5:00am PST, 8:00am EST The diagnosis of an active infection by the hepatitis B virus (HBV) relies on testing for the HBV surface antigen (HBsAg). Ov...
      Speaker: Claudio Galli, MD, PhD
      Sponsored By: Abbott
      16 1
      NOV 19, 2019 | 10:00 AM
      LC3-associated endocytosis: guarding against neuroinflammation & neurodegeneration
      LC3-associated endocytosis: guarding against neuroinflammation...
      DATE: November 19, 2019TIME: 10:00am PSTMicroglial cells are the resident innate immune cells of the central nervous system (CNS) and are responsible for regulating inflammatory activati...
      Speaker: Bradlee L. Heckmann, Ph.D.
      Sponsored By: Miltenyi Biotec
      6
      NOV 14, 2019 | 12:00 PM
      Thyroid autoimmunity and female infertility
      Thyroid autoimmunity and female infertility
      Thyroid autoimmunity (TAI) tends to be more common in women consulting for fertility problems. However, any underlying causal mechanism connecting TAI to fertility aspects is yet to be establ...
      Speaker: David Unuane, MD, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
      4
      NOV 06, 2019 | 1:30 PM
      Challenges towards a Universal Influenza Virus Vaccine
      Challenges towards a Universal Influenza Virus Vaccine
      Despite FDA-approved vaccines and antivirals, seasonal and pandemic influenza remains a serious threat associated with substantial morbidity and mortality. The present modalities and vaccine...
      Speaker: Peter Palese, PhD
      Presented at: Influenza Virtual Event Series 2019
      4 1
      NOV 06, 2019 | 7:30 AM
      Toward a universal influenza virus vaccine
      Toward a universal influenza virus vaccine
      Since the establishment of reverse genetics techniques to manipulate the influenza virus genome, it has been possible to study viral molecular signatures responsible for virulence, and the ge...
      Speaker: Adolfo Garcia-Sastre, PhD
      Presented at: Influenza Virtual Event Series 2019
      4
      OCT 31, 2019 | 9:00 AM
      Investigation of Endothelial Cell Viability and Growth on 3D printed GelMa Vascular Networks
      Investigation of Endothelial Cell Viability and Growth on 3D printed...
      DATE: October 31, 2019TIME: 9:00am PDT, 12:00pm EDT INTRODUCTION: A major limitation for the development of 3D engineered tissues is the absence of viable and perfusable...
      Speaker: Chrisoula Chappell
      Sponsored By: Thermo Fisher Scientific/Gibco
      8
      OCT 30, 2019 | 7:00 AM
      A Novel Approach for Single-cell Multi-omic Analysis to Identify Regulatory Signatures in Cancer
      A Novel Approach for Single-cell Multi-omic Analysis to Identify...
      DATE: October 30, 2019TIME: 7:00am PDTJoin us for a webinar to learn how to apply single cell methods to study cancer. Dr. William Greenleaf, Associate Professor from Stanford Universit...
      Speaker: William J. Greenleaf, Ph.D
      Sponsored By: 10x Genomics
      18 1
      OCT 29, 2019 | 8:00 AM
      Multi-omics Approach to Understanding PD-L1 Resistance in Cancer
      Multi-omics Approach to Understanding PD-L1 Resistance in Cancer
      DATE: October 29, 2019TIME: 8:00am PDTAlthough immune-based therapies targeting the inhibitory receptors (PD-L1, PD1, and CTLA4) are proven to be effective to treat cancer, some pati...
      Speaker: Moshe Sade Feldman (PhD) , Russell Jenkins MD, PhD
      Sponsored By: Sony Biotechnology
      8
      OCT 10, 2019 | 1:30 PM
      Precision oncology: Biomarkers for treatment selection in metastatic castration resistant prostate cancer
      Precision oncology: Biomarkers for treatment selection in metastatic...
      Metastatic castration resistant prostate cancer (mCRPC) refractory to secondary hormonal treatments such as enzalutamide or abiraterone acetate are the most lethal of prostate cancers. In thi...
      Speaker: Tian Zhang, MD, MHS
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      1
      OCT 10, 2019 | 12:00 PM
      Tumor Mutation Burden: Challenges and opportunities of measuring and interpreting tumor mutational burden for patient care
      Tumor Mutation Burden: Challenges and opportunities of measuring...
      Tumor mutational burden (TMB) is an emerging biomarker that correlates with response to immunotherapeutic agents, such as checkpoint inhibitors. Recent studies indicate that a high mutation l...
      Speaker: Ravindra Kolhe, MD, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      Sponsored By: QIAGEN
      1
      OCT 10, 2019 | 10:30 AM
      Transcriptional Profiling of the Pediatric Tumor Microenvironment
      Transcriptional Profiling of the Pediatric Tumor Microenvironment
      Osteosarcoma (OS) is the most common bone tumor in pediatric and adolescent/young adult patients. Over the past three decades, significant improvements in the survival rates or therapeutic ap...
      Speaker: Troy McEachron, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      Sponsored By: NanoString Technologies
      1
      OCT 10, 2019 | 9:00 AM
      Dynamic evolution of unstable genomes: insights from in vitro experiments and cancer genome analysis
      Dynamic evolution of unstable genomes: insights from in vitro...
      Copy-number alterations and chromosomal translocations are widespread in cancer and frequently causing oncogenic mutations that drive tumorigenesis and therapy resistance. Despite their preva...
      Speaker: Cheng-Zhong Zhang, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      1
      OCT 10, 2019 | 9:00 AM
      Next Generation Targets for Immuno-Oncology
      Next Generation Targets for Immuno-Oncology
      Blockade of CTLA-4 and PD-1, members of the B7/CD28 family, have proven to be the most successful cancer immunotherapies to date. While the current therapeutic focus remains on B7/CD28 family...
      Speaker: Anthony Persen, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      Sponsored By: ACD - A Bio-Techne Brand
      1
      OCT 09, 2019 | 9:00 AM
      Start at the End: A Strategy for Developing and Delivering Advanced Diagnostic Tests to improve Prostate Cancer Patient Outcomes
      Start at the End: A Strategy for Developing and Delivering Advanced...
      Although about one in every seven men in the developed world will be diagnosed with prostate cancer in their lifetime, the mortality rate remains low with a 99% five-year survival rate for lo...
      Speaker: Stephen Pennington
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      Sponsored By: Agilent
      1
      OCT 03, 2019 | 3:00 PM
      'Any Idiot can do it'.  How easy a knockout or knockin mouse could be generated using CRISPR/Cas9 gene editing technology?
      'Any Idiot can do it'. How easy a knockout or knockin mouse could...
      Novel precision genetic technologies such as CRISPR/Cas9 genome editing technology offer novel avenues to a better understanding the mechanisms of diseases. Using CRISPR/Cas9 we are able to p...
      Speaker: Gaetan Burgio, Msc, MBBS, MD, PhD
      Presented at: CRISPR Virtual Event Series 2019
      3
      OCT 03, 2019 | 9:00 AM
      Application of CRISPR-Cas9 in plants
      Application of CRISPR-Cas9 in plants
      CRISPR-Cas9 based gene editing is a powerful tool which can induce heritable mutations at desired genomic loci without leaving transgenic trace in plants. Here we constructed a robust, multip...
      Speaker: Xing-Liang Ma, PhD
      Presented at: CRISPR Virtual Event Series 2019
      2
      OCT 03, 2019 | 6:00 AM
      CRISPR Regulations: Rewriting DNA and Rethinking GMOs
      CRISPR Regulations: Rewriting DNA and Rethinking GMOs
      First discovered as a genome-editing tool just seven years ago, CRISPR systems have already changed the face of basic research, allowing researchers to alter the DNA of hundreds of organisms...
      Speaker: Lea Witkowsky, PhD
      Presented at: CRISPR Virtual Event Series 2019
      5
      OCT 02, 2019 | 9:00 AM
      Empower electrophysiology data analysis with new Clampfit 11 Advanced Event Detection
      Empower electrophysiology data analysis with new Clampfit 11 Advanced...
      DATE: October 2, 2019TIME: 9:00am PTThe Clampfit software module is a useful tool to manipulate and analyze electrophysiological data acquired by pCLAMP™ software. Recently, Mol...
      Speaker: Jin Yan, Ph.D.
      Sponsored By: Molecular Devices
      4
      SEP 30, 2019 | 8:00 AM
      Discovery and Verification of eQTLs Associated with Lung Adenocarcinoma
      Discovery and Verification of eQTLs Associated with Lung Adenocarcinoma
      DATE: September 30, 2019TIME: 8:00am PDT, 11:00am EDT, 5:00pm CEST Expression quantitative trait loci (eQTLs) are SNPs that have an influence on expression levels of genes, and the ident...
      Speaker: Tommaso Dragani , Harita Veereshlingam, PhD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      9
      SEP 27, 2019 | 9:00 AM
      Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
      Investigating how Tpz-1 may be used as a novel therapeutic agent...
      DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
      Speaker: Jessica Hess
      Sponsored By: Thermo Fisher Scientific/Gibco
      5
      SEP 26, 2019 | 12:00 PM
      Understanding the Regulation of Membrane Curvature During Mating in Tetrahymena Thermophila
      Understanding the Regulation of Membrane Curvature During Mating...
      The active shaping of biological membranes is essential for a variety of cellular functions including but not limited to cell migration, cell division, organelle morphology, and cell and memb...
      Speaker: Sabrice Guerrier, PhD
      Presented at: Cell Biology Virtual Event Series 2019
      2
      SEP 26, 2019 | 6:00 AM
      The reciprocal relationship between cytokine dysregulation and binge alcohol consumption
      The reciprocal relationship between cytokine dysregulation and...
      Neuroinflammation has been implicated as a factor in alcohol-induced neurodegeneration, but the role of the neuroimmune system in alcohol consumption has only recently come to the forefront....
      Speaker: S. Alex Marshall, PhD
      Presented at: Cell Biology Virtual Event Series 2019
      2
    JAN 01, 2020 | 6:00 AM
    Uncovering the mechanism of stress-resistant DNA replication in cancer cells using a modern single-molecule technique
    Uncovering the mechanism of stress-resistant DNA replication in...
    Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
    Speaker: Chames Kermi, PhD, PharmD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    DEC 17, 2019 | 8:00 AM
    Single-Cell Phosphoprotein Analysis with CyTOF: From Training to Immuno-Oncology Clinical Research
    Single-Cell Phosphoprotein Analysis with CyTOF: From Training...
    DATE: December 17, 2019TIME: 8:00am PSTMass cytometry instruments simultaneously measure >50 cellular features, with a typical experiment including millions of cells. Dysregulated...
    Speaker: Jonathan Irish, PhD , Caroline E. Roe, BS
    Sponsored By: Standard BioTools
    7 2
    DEC 05, 2019 | 5:00 AM
    The clinical implications of high sensitive assays for HBsAg
    The clinical implications of high sensitive assays for HBsAg
    DATE: December 5, 2019TIME: 5:00am PST, 8:00am EST The diagnosis of an active infection by the hepatitis B virus (HBV) relies on testing for the HBV surface antigen (HBsAg). Ov...
    Speaker: Claudio Galli, MD, PhD
    Sponsored By: Abbott
    16 1
    NOV 19, 2019 | 10:00 AM
    LC3-associated endocytosis: guarding against neuroinflammation & neurodegeneration
    LC3-associated endocytosis: guarding against neuroinflammation...
    DATE: November 19, 2019TIME: 10:00am PSTMicroglial cells are the resident innate immune cells of the central nervous system (CNS) and are responsible for regulating inflammatory activati...
    Speaker: Bradlee L. Heckmann, Ph.D.
    Sponsored By: Miltenyi Biotec
    6
    NOV 14, 2019 | 12:00 PM
    Thyroid autoimmunity and female infertility
    Thyroid autoimmunity and female infertility
    Thyroid autoimmunity (TAI) tends to be more common in women consulting for fertility problems. However, any underlying causal mechanism connecting TAI to fertility aspects is yet to be establ...
    Speaker: David Unuane, MD, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
    4
     
     
  • NOV 06, 2019 | 1:30 PM
    Challenges towards a Universal Influenza Virus Vaccine
    Challenges towards a Universal Influenza Virus Vaccine
    Despite FDA-approved vaccines and antivirals, seasonal and pandemic influenza remains a serious threat associated with substantial morbidity and mortality. The present modalities and vaccine...
    Speaker: Peter Palese, PhD
    Presented at: Influenza Virtual Event Series 2019
    4 1
    NOV 06, 2019 | 7:30 AM
    Toward a universal influenza virus vaccine
    Toward a universal influenza virus vaccine
    Since the establishment of reverse genetics techniques to manipulate the influenza virus genome, it has been possible to study viral molecular signatures responsible for virulence, and the ge...
    Speaker: Adolfo Garcia-Sastre, PhD
    Presented at: Influenza Virtual Event Series 2019
    4
    OCT 31, 2019 | 9:00 AM
    Investigation of Endothelial Cell Viability and Growth on 3D printed GelMa Vascular Networks
    Investigation of Endothelial Cell Viability and Growth on 3D printed...
    DATE: October 31, 2019TIME: 9:00am PDT, 12:00pm EDT INTRODUCTION: A major limitation for the development of 3D engineered tissues is the absence of viable and perfusable...
    Speaker: Chrisoula Chappell
    Sponsored By: Thermo Fisher Scientific/Gibco
    8
    OCT 30, 2019 | 7:00 AM
    A Novel Approach for Single-cell Multi-omic Analysis to Identify Regulatory Signatures in Cancer
    A Novel Approach for Single-cell Multi-omic Analysis to Identify...
    DATE: October 30, 2019TIME: 7:00am PDTJoin us for a webinar to learn how to apply single cell methods to study cancer. Dr. William Greenleaf, Associate Professor from Stanford Universit...
    Speaker: William J. Greenleaf, Ph.D
    Sponsored By: 10x Genomics
    18 1
    OCT 29, 2019 | 8:00 AM
    Multi-omics Approach to Understanding PD-L1 Resistance in Cancer
    Multi-omics Approach to Understanding PD-L1 Resistance in Cancer
    DATE: October 29, 2019TIME: 8:00am PDTAlthough immune-based therapies targeting the inhibitory receptors (PD-L1, PD1, and CTLA4) are proven to be effective to treat cancer, some pati...
    Speaker: Moshe Sade Feldman (PhD) , Russell Jenkins MD, PhD
    Sponsored By: Sony Biotechnology
    8
     
     
  • OCT 10, 2019 | 1:30 PM
    Precision oncology: Biomarkers for treatment selection in metastatic castration resistant prostate cancer
    Precision oncology: Biomarkers for treatment selection in metastatic...
    Metastatic castration resistant prostate cancer (mCRPC) refractory to secondary hormonal treatments such as enzalutamide or abiraterone acetate are the most lethal of prostate cancers. In thi...
    Speaker: Tian Zhang, MD, MHS
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    1
    OCT 10, 2019 | 12:00 PM
    Tumor Mutation Burden: Challenges and opportunities of measuring and interpreting tumor mutational burden for patient care
    Tumor Mutation Burden: Challenges and opportunities of measuring...
    Tumor mutational burden (TMB) is an emerging biomarker that correlates with response to immunotherapeutic agents, such as checkpoint inhibitors. Recent studies indicate that a high mutation l...
    Speaker: Ravindra Kolhe, MD, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    Sponsored By: QIAGEN
    1
    OCT 10, 2019 | 10:30 AM
    Transcriptional Profiling of the Pediatric Tumor Microenvironment
    Transcriptional Profiling of the Pediatric Tumor Microenvironment
    Osteosarcoma (OS) is the most common bone tumor in pediatric and adolescent/young adult patients. Over the past three decades, significant improvements in the survival rates or therapeutic ap...
    Speaker: Troy McEachron, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    Sponsored By: NanoString Technologies
    1
    OCT 10, 2019 | 9:00 AM
    Dynamic evolution of unstable genomes: insights from in vitro experiments and cancer genome analysis
    Dynamic evolution of unstable genomes: insights from in vitro...
    Copy-number alterations and chromosomal translocations are widespread in cancer and frequently causing oncogenic mutations that drive tumorigenesis and therapy resistance. Despite their preva...
    Speaker: Cheng-Zhong Zhang, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    1
    OCT 10, 2019 | 9:00 AM
    Next Generation Targets for Immuno-Oncology
    Next Generation Targets for Immuno-Oncology
    Blockade of CTLA-4 and PD-1, members of the B7/CD28 family, have proven to be the most successful cancer immunotherapies to date. While the current therapeutic focus remains on B7/CD28 family...
    Speaker: Anthony Persen, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    Sponsored By: ACD - A Bio-Techne Brand
    1
     
     
  • OCT 09, 2019 | 9:00 AM
    Start at the End: A Strategy for Developing and Delivering Advanced Diagnostic Tests to improve Prostate Cancer Patient Outcomes
    Start at the End: A Strategy for Developing and Delivering Advanced...
    Although about one in every seven men in the developed world will be diagnosed with prostate cancer in their lifetime, the mortality rate remains low with a 99% five-year survival rate for lo...
    Speaker: Stephen Pennington
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    Sponsored By: Agilent
    1
    OCT 03, 2019 | 3:00 PM
    'Any Idiot can do it'.  How easy a knockout or knockin mouse could be generated using CRISPR/Cas9 gene editing technology?
    'Any Idiot can do it'. How easy a knockout or knockin mouse could...
    Novel precision genetic technologies such as CRISPR/Cas9 genome editing technology offer novel avenues to a better understanding the mechanisms of diseases. Using CRISPR/Cas9 we are able to p...
    Speaker: Gaetan Burgio, Msc, MBBS, MD, PhD
    Presented at: CRISPR Virtual Event Series 2019
    3
    OCT 03, 2019 | 9:00 AM
    Application of CRISPR-Cas9 in plants
    Application of CRISPR-Cas9 in plants
    CRISPR-Cas9 based gene editing is a powerful tool which can induce heritable mutations at desired genomic loci without leaving transgenic trace in plants. Here we constructed a robust, multip...
    Speaker: Xing-Liang Ma, PhD
    Presented at: CRISPR Virtual Event Series 2019
    2
    OCT 03, 2019 | 6:00 AM
    CRISPR Regulations: Rewriting DNA and Rethinking GMOs
    CRISPR Regulations: Rewriting DNA and Rethinking GMOs
    First discovered as a genome-editing tool just seven years ago, CRISPR systems have already changed the face of basic research, allowing researchers to alter the DNA of hundreds of organisms...
    Speaker: Lea Witkowsky, PhD
    Presented at: CRISPR Virtual Event Series 2019
    5
    OCT 02, 2019 | 9:00 AM
    Empower electrophysiology data analysis with new Clampfit 11 Advanced Event Detection
    Empower electrophysiology data analysis with new Clampfit 11 Advanced...
    DATE: October 2, 2019TIME: 9:00am PTThe Clampfit software module is a useful tool to manipulate and analyze electrophysiological data acquired by pCLAMP™ software. Recently, Mol...
    Speaker: Jin Yan, Ph.D.
    Sponsored By: Molecular Devices
    4
     
     
  • SEP 30, 2019 | 8:00 AM
    Discovery and Verification of eQTLs Associated with Lung Adenocarcinoma
    Discovery and Verification of eQTLs Associated with Lung Adenocarcinoma
    DATE: September 30, 2019TIME: 8:00am PDT, 11:00am EDT, 5:00pm CEST Expression quantitative trait loci (eQTLs) are SNPs that have an influence on expression levels of genes, and the ident...
    Speaker: Tommaso Dragani , Harita Veereshlingam, PhD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    9
    SEP 27, 2019 | 9:00 AM
    Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
    Investigating how Tpz-1 may be used as a novel therapeutic agent...
    DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
    Speaker: Jessica Hess
    Sponsored By: Thermo Fisher Scientific/Gibco
    5
    SEP 26, 2019 | 12:00 PM
    Understanding the Regulation of Membrane Curvature During Mating in Tetrahymena Thermophila
    Understanding the Regulation of Membrane Curvature During Mating...
    The active shaping of biological membranes is essential for a variety of cellular functions including but not limited to cell migration, cell division, organelle morphology, and cell and memb...
    Speaker: Sabrice Guerrier, PhD
    Presented at: Cell Biology Virtual Event Series 2019
    2
    SEP 26, 2019 | 6:00 AM
    The reciprocal relationship between cytokine dysregulation and binge alcohol consumption
    The reciprocal relationship between cytokine dysregulation and...
    Neuroinflammation has been implicated as a factor in alcohol-induced neurodegeneration, but the role of the neuroimmune system in alcohol consumption has only recently come to the forefront....
    Speaker: S. Alex Marshall, PhD
    Presented at: Cell Biology Virtual Event Series 2019
    2
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