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    Molecular Genetics

    Molecular Genetics: is the field of biology that studies the structure and function of genes at a molecular level, simultaneously using both molecular biology and genetics. This typically refers to the laboratory techniques used to identify or manipulate DNA segments that are involved in synthesis of important biological molecules.

    Webinars

    • FEB 04, 2015 | 6:00 AM
      C.E. CREDITS
      PCR testing in rodent health monitoring program: where are we exactly?
      PCR testing in rodent health monitoring program: where are we...
      Soiled-bedding sentinels are not always efficient in detecting pathogens in rodent colonies. In this context, PCR-based testing can be more sensitive and is being advocated as adjunct to trad...
      Speaker: Mathias Leblanc, DVM, PhD, DES, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      33
      JAN 28, 2015 | 8:00 AM
      Automated 3D Cell Culture and Screening by Imaging and Flow Cytometry
      Automated 3D Cell Culture and Screening by Imaging and Flow Cytometry
      Drug developers are rapidly adopting three-dimensional (3D) cell cultures for drug screening since they provide a more physiologically relevant environment than two-dimensional cell cultures ...
      Speaker: Nicky Slawny, PhD , Mike Kowalski, Ph.D.
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      0
      OCT 30, 2014 | 1:30 PM
      Dissecting cancer signaling pathways with chemical scalpels
      Dissecting cancer signaling pathways with chemical scalpels
      Advances in genomic research have led to identification of the majority of the drivers of tumor progression. However, our understanding of the molecular mechanisms propelling tumor growth is...
      Speaker: Nadya Tarasova, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      14
      OCT 30, 2014 | 12:00 PM
      Breast-Predict: Leveraging the Power of Systems Medicine Towards Personalized Cancer Therapy
      Breast-Predict: Leveraging the Power of Systems Medicine Towards...
      Although the incidence of breast cancer is steadily increasing, mortality rates are decreasing. This means that the majority of women with breast cancer now survive, making it even more impor...
      Speaker: William M. Gallagher, BSc PhD CBiol MSB
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
      OCT 30, 2014 | 10:30 AM
      Development of molecularly targeted imaging agents and identification of novel targets in cancer
      Development of molecularly targeted imaging agents and identification...
      The era of omics has ushered in the hope for personalized medicine. Proteomic and genomic strategies that allow unbiased identification of genes and proteins and their post-transcriptional a...
      Speaker: Kimberly Kelly , PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      16
      OCT 30, 2014 | 10:30 AM
      Genomics in the Clinic: Promises and Challenges
      Genomics in the Clinic: Promises and Challenges
      Uncovering the genetic lesions underpinning cancer through genomic profiling in a clinical setting could provide insights into possible treatment options for oncologists and their patients. N...
      Speaker: John Carpten, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
      OCT 30, 2014 | 9:00 AM
      A head-to-head comparison of whole blood derived samples (cfDNA vs CTC DNA) for cancer research using next-generation sequencing
      A head-to-head comparison of whole blood derived samples (cfDNA...
      Both cell free DNA (cfDNA) and circulating tumor cells (CTC) represent important possible templates for mutation analysis of clinical samples. Each template has different theoretical advantag...
      Speaker: Paul W. Dempsey, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      0
      OCT 29, 2014 | 3:00 PM
      Transforming the future of oncology with genomics
      Transforming the future of oncology with genomics
      Illumina next-generation sequencing (NGS) and microarray technologies are revolutionizing cancer research, enabling cancer variant discovery and detection and molecular monitoring. Join u...
      Speaker: Jennifer Stone, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      13
      OCT 29, 2014 | 3:00 PM
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
      Speaker: Michael J Mann, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      67
      OCT 29, 2014 | 3:00 PM
      Drug-tailored, efficacy-predictive and prognostic biomarker approaches for proper patient selection
      Drug-tailored, efficacy-predictive and prognostic biomarker approaches...
      Over the last decade we have witnessed tremendous advances in our understanding of the underlying molecular alterations in human cancer. This has stimulated excitement for our ability to deve...
      Speaker: Peter Blume-Jensen, MD, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      0
      OCT 29, 2014 | 10:30 AM
      Learning from the Pointillists - Using Big Data Approaches to Embrace the Complexity of Cancer
      Learning from the Pointillists - Using Big Data Approaches to...
      The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
      Speaker: Kenneth Buetow, PhD, FACMI
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      14
      OCT 29, 2014 | 9:00 AM
      miRNA Biomarker Discovery: Technologies, workflows, and data analysis solutions for discovering your unique signature
      miRNA Biomarker Discovery: Technologies, workflows, and data analysis...
      Circulating miRNAs have great potential as biomarkers due to their aberrant expression in cancer and other diseases. However, miRNAs from body fluids are hard to obtain in amounts sufficient...
      Speaker: Jonathan Shaffer, PhD, MBA
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      18
      SEP 16, 2014 | 10:00 AM
      Expanded clinical research opportunities for Crizotinib identified from an analysis of over 5,000 exomes
      Expanded clinical research opportunities for Crizotinib identified...
      Patients with chromosomal rearrangements resulting in fusion proteins are among the most responsive to published targeted therapy. For example, targeting of the EML4-ALK fusion in non-small c...
      Speaker: Sean Eddy, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
      12
      AUG 21, 2014 | 11:30 AM
      Understanding the Genetics of Common Disease:  Using Big Data approaches to see the emergent whole
      Understanding the Genetics of Common Disease: Using Big Data...
      The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
      Speaker: Kenneth Buetow, PhD, FACMI
      Presented at: Genetics and Genomics Virtual Event Series 2014
      198
      AUG 21, 2014 | 11:15 AM
      Keynote: Integration of Genetics and Genomics into Medical Practice: Educational Challenges
      Keynote: Integration of Genetics and Genomics into Medical Practice:...
      Medical applications of genetics and genomics have been advancing dramatically since completion of the sequencing of the human genome. The cost of DNA sequencing has plummeted, leading to the...
      Speaker: Bruce R. Korf, MD, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      76
      AUG 21, 2014 | 9:45 AM
      Pathway based analyses for genetic susceptibility to cancer and autoimmune disease
      Pathway based analyses for genetic susceptibility to cancer and...
      In this presentation I describe pathway based analyses of genotyping data to identify pathways related to the development of complex diseases, with a focus on lung cancer and selected autoimm...
      Speaker: Christopher I Amos, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      62
      AUG 21, 2014 | 8:45 AM
      Genome and exome sequencing in a clinical laboratory
      Genome and exome sequencing in a clinical laboratory
      With advances in next-generation sequencing, whole-exome and genome sequencing (WGES) is now accessible as a tool in many applications. In the clinical setting, WGES is proving to be very val...
      Speaker: Matthew Lebo, PhD, FACMG
      Presented at: Genetics and Genomics Virtual Event Series 2014
      30
      AUG 21, 2014 | 8:45 AM
      From Genetics to Genetic Medicine: Gene Therapy for vision restoration as a case study
      From Genetics to Genetic Medicine: Gene Therapy for vision restoration...
      Gene therapy for two forms of inherited retinal degeneration have met promising safety and efficacy endpoints in early stage clinical trials. These approaches made use of a replication defect...
      Speaker: Luk H Vandenberghe, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      0
      AUG 21, 2014 | 7:30 AM
      Keynote: Clinical Validity and Utility in Whole Exome/Genome Sequencing
      Keynote: Clinical Validity and Utility in Whole Exome/Genome Sequencing
      ...
      Speaker: Robert Nussbaum, MD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      48
      AUG 21, 2014 | 6:45 AM
      Practical Considerations for the Clinical Interpretation of Germline Sequence Variants in the Era of NGS
      Practical Considerations for the Clinical Interpretation of Germline...
      The advent of next generation sequencing technologies has revolutionized the clinical genetics laboratory. Labs offering NGS are faced with an onslaught of sequence variants which must be int...
      Speaker: Heather McLaughlin, PhD, MB(ASCP)CM
      Presented at: Genetics and Genomics Virtual Event Series 2014
      68
      AUG 20, 2014 | 11:30 AM
      More Comprehensive Views of Human Genetic Variation
      More Comprehensive Views of Human Genetic Variation
      High-throughput short-read DNA sequencing has revolutionized our ability to measure genetic variation in the form of single-nucleotide polymorphisms (SNPs) in human genomes. However, ~75% of...
      Speaker: Jonas Korlach, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      8
      AUG 20, 2014 | 10:45 AM
      OncoScan Assay for copy number from FFPE. Publications & cases on actionable CNV detection
      OncoScan Assay for copy number from FFPE. Publications & cases...
      A recent publication in Nature Genetics1 analyzed TCGA data, and classified solid tumors into two mutually exclusive classes: C class tumors, driven by copy number alterations; and M class tu...
      Speaker: Padma Sundar, MBA, MPH
      Presented at: Genetics and Genomics Virtual Event Series 2014
      14
      AUG 20, 2014 | 8:45 AM
      Digitizing Life Using Synthetic Genomics
      Digitizing Life Using Synthetic Genomics
      In 2010, our team of synthetic biologists announced the creation of a bacterial cell that had a chemically synthesized genome. To build this synthetic Mycoplasma mycoides JCVI 1.0 we had to d...
      Speaker: John Glass, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      135
      AUG 20, 2014 | 8:45 AM
      Novel gene chip technologies and NGS sequencing for personalized medicine & diagnostic
      Novel gene chip technologies and NGS sequencing for personalized...
      The flexibility of the BioMark Real-Time PCR System, allow us to preform genetic research using different types of nano-fluidic (48.48 or 96.96) chips setup, in the thermal cycle of these chi...
      Speaker: Dani Bercovich, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      12
    FEB 04, 2015 | 6:00 AM
    C.E. CREDITS
    PCR testing in rodent health monitoring program: where are we exactly?
    PCR testing in rodent health monitoring program: where are we...
    Soiled-bedding sentinels are not always efficient in detecting pathogens in rodent colonies. In this context, PCR-based testing can be more sensitive and is being advocated as adjunct to trad...
    Speaker: Mathias Leblanc, DVM, PhD, DES, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    33
    JAN 28, 2015 | 8:00 AM
    Automated 3D Cell Culture and Screening by Imaging and Flow Cytometry
    Automated 3D Cell Culture and Screening by Imaging and Flow Cytometry
    Drug developers are rapidly adopting three-dimensional (3D) cell cultures for drug screening since they provide a more physiologically relevant environment than two-dimensional cell cultures ...
    Speaker: Nicky Slawny, PhD , Mike Kowalski, Ph.D.
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    0
    OCT 30, 2014 | 1:30 PM
    Dissecting cancer signaling pathways with chemical scalpels
    Dissecting cancer signaling pathways with chemical scalpels
    Advances in genomic research have led to identification of the majority of the drivers of tumor progression. However, our understanding of the molecular mechanisms propelling tumor growth is...
    Speaker: Nadya Tarasova, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    14
    OCT 30, 2014 | 12:00 PM
    Breast-Predict: Leveraging the Power of Systems Medicine Towards Personalized Cancer Therapy
    Breast-Predict: Leveraging the Power of Systems Medicine Towards...
    Although the incidence of breast cancer is steadily increasing, mortality rates are decreasing. This means that the majority of women with breast cancer now survive, making it even more impor...
    Speaker: William M. Gallagher, BSc PhD CBiol MSB
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    12
    OCT 30, 2014 | 10:30 AM
    Development of molecularly targeted imaging agents and identification of novel targets in cancer
    Development of molecularly targeted imaging agents and identification...
    The era of omics has ushered in the hope for personalized medicine. Proteomic and genomic strategies that allow unbiased identification of genes and proteins and their post-transcriptional a...
    Speaker: Kimberly Kelly , PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    16
     
     
  • OCT 30, 2014 | 10:30 AM
    Genomics in the Clinic: Promises and Challenges
    Genomics in the Clinic: Promises and Challenges
    Uncovering the genetic lesions underpinning cancer through genomic profiling in a clinical setting could provide insights into possible treatment options for oncologists and their patients. N...
    Speaker: John Carpten, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    12
    OCT 30, 2014 | 9:00 AM
    A head-to-head comparison of whole blood derived samples (cfDNA vs CTC DNA) for cancer research using next-generation sequencing
    A head-to-head comparison of whole blood derived samples (cfDNA...
    Both cell free DNA (cfDNA) and circulating tumor cells (CTC) represent important possible templates for mutation analysis of clinical samples. Each template has different theoretical advantag...
    Speaker: Paul W. Dempsey, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    0
    OCT 29, 2014 | 3:00 PM
    Transforming the future of oncology with genomics
    Transforming the future of oncology with genomics
    Illumina next-generation sequencing (NGS) and microarray technologies are revolutionizing cancer research, enabling cancer variant discovery and detection and molecular monitoring. Join u...
    Speaker: Jennifer Stone, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    13
    OCT 29, 2014 | 3:00 PM
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
    Speaker: Michael J Mann, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    67
    OCT 29, 2014 | 3:00 PM
    Drug-tailored, efficacy-predictive and prognostic biomarker approaches for proper patient selection
    Drug-tailored, efficacy-predictive and prognostic biomarker approaches...
    Over the last decade we have witnessed tremendous advances in our understanding of the underlying molecular alterations in human cancer. This has stimulated excitement for our ability to deve...
    Speaker: Peter Blume-Jensen, MD, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    0
     
     
  • OCT 29, 2014 | 10:30 AM
    Learning from the Pointillists - Using Big Data Approaches to Embrace the Complexity of Cancer
    Learning from the Pointillists - Using Big Data Approaches to...
    The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
    Speaker: Kenneth Buetow, PhD, FACMI
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    14
    OCT 29, 2014 | 9:00 AM
    miRNA Biomarker Discovery: Technologies, workflows, and data analysis solutions for discovering your unique signature
    miRNA Biomarker Discovery: Technologies, workflows, and data analysis...
    Circulating miRNAs have great potential as biomarkers due to their aberrant expression in cancer and other diseases. However, miRNAs from body fluids are hard to obtain in amounts sufficient...
    Speaker: Jonathan Shaffer, PhD, MBA
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    18
    SEP 16, 2014 | 10:00 AM
    Expanded clinical research opportunities for Crizotinib identified from an analysis of over 5,000 exomes
    Expanded clinical research opportunities for Crizotinib identified...
    Patients with chromosomal rearrangements resulting in fusion proteins are among the most responsive to published targeted therapy. For example, targeting of the EML4-ALK fusion in non-small c...
    Speaker: Sean Eddy, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
    12
    AUG 21, 2014 | 11:30 AM
    Understanding the Genetics of Common Disease:  Using Big Data approaches to see the emergent whole
    Understanding the Genetics of Common Disease: Using Big Data...
    The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
    Speaker: Kenneth Buetow, PhD, FACMI
    Presented at: Genetics and Genomics Virtual Event Series 2014
    198
    AUG 21, 2014 | 11:15 AM
    Keynote: Integration of Genetics and Genomics into Medical Practice: Educational Challenges
    Keynote: Integration of Genetics and Genomics into Medical Practice:...
    Medical applications of genetics and genomics have been advancing dramatically since completion of the sequencing of the human genome. The cost of DNA sequencing has plummeted, leading to the...
    Speaker: Bruce R. Korf, MD, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    76
     
     
  • AUG 21, 2014 | 9:45 AM
    Pathway based analyses for genetic susceptibility to cancer and autoimmune disease
    Pathway based analyses for genetic susceptibility to cancer and...
    In this presentation I describe pathway based analyses of genotyping data to identify pathways related to the development of complex diseases, with a focus on lung cancer and selected autoimm...
    Speaker: Christopher I Amos, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    62
    AUG 21, 2014 | 8:45 AM
    Genome and exome sequencing in a clinical laboratory
    Genome and exome sequencing in a clinical laboratory
    With advances in next-generation sequencing, whole-exome and genome sequencing (WGES) is now accessible as a tool in many applications. In the clinical setting, WGES is proving to be very val...
    Speaker: Matthew Lebo, PhD, FACMG
    Presented at: Genetics and Genomics Virtual Event Series 2014
    30
    AUG 21, 2014 | 8:45 AM
    From Genetics to Genetic Medicine: Gene Therapy for vision restoration as a case study
    From Genetics to Genetic Medicine: Gene Therapy for vision restoration...
    Gene therapy for two forms of inherited retinal degeneration have met promising safety and efficacy endpoints in early stage clinical trials. These approaches made use of a replication defect...
    Speaker: Luk H Vandenberghe, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    0
    AUG 21, 2014 | 7:30 AM
    Keynote: Clinical Validity and Utility in Whole Exome/Genome Sequencing
    Keynote: Clinical Validity and Utility in Whole Exome/Genome Sequencing
    ...
    Speaker: Robert Nussbaum, MD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    48
    AUG 21, 2014 | 6:45 AM
    Practical Considerations for the Clinical Interpretation of Germline Sequence Variants in the Era of NGS
    Practical Considerations for the Clinical Interpretation of Germline...
    The advent of next generation sequencing technologies has revolutionized the clinical genetics laboratory. Labs offering NGS are faced with an onslaught of sequence variants which must be int...
    Speaker: Heather McLaughlin, PhD, MB(ASCP)CM
    Presented at: Genetics and Genomics Virtual Event Series 2014
    68
     
     
  • AUG 20, 2014 | 11:30 AM
    More Comprehensive Views of Human Genetic Variation
    More Comprehensive Views of Human Genetic Variation
    High-throughput short-read DNA sequencing has revolutionized our ability to measure genetic variation in the form of single-nucleotide polymorphisms (SNPs) in human genomes. However, ~75% of...
    Speaker: Jonas Korlach, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    8
    AUG 20, 2014 | 10:45 AM
    OncoScan Assay for copy number from FFPE. Publications & cases on actionable CNV detection
    OncoScan Assay for copy number from FFPE. Publications & cases...
    A recent publication in Nature Genetics1 analyzed TCGA data, and classified solid tumors into two mutually exclusive classes: C class tumors, driven by copy number alterations; and M class tu...
    Speaker: Padma Sundar, MBA, MPH
    Presented at: Genetics and Genomics Virtual Event Series 2014
    14
    AUG 20, 2014 | 8:45 AM
    Digitizing Life Using Synthetic Genomics
    Digitizing Life Using Synthetic Genomics
    In 2010, our team of synthetic biologists announced the creation of a bacterial cell that had a chemically synthesized genome. To build this synthetic Mycoplasma mycoides JCVI 1.0 we had to d...
    Speaker: John Glass, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    135
    AUG 20, 2014 | 8:45 AM
    Novel gene chip technologies and NGS sequencing for personalized medicine & diagnostic
    Novel gene chip technologies and NGS sequencing for personalized...
    The flexibility of the BioMark Real-Time PCR System, allow us to preform genetic research using different types of nano-fluidic (48.48 or 96.96) chips setup, in the thermal cycle of these chi...
    Speaker: Dani Bercovich, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    12
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