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    Research

    Research: comprises "creative and systematic work undertaken to increase the stock of knowledge, including knowledge of humans, culture and society, and the use of this stock of knowledge to devise new applications."

    Webinars

    • OCT 30, 2014 | 7:30 AM
      Challenges in biomarker testing in non-small cell lung cancer research
      Challenges in biomarker testing in non-small cell lung cancer...
      Fusion genes play a central role in many cancer types. They have been used to classify malignancy, risk factors, disease prognosis, and companion diagnostic biomarkers for certain approved dr...
      Speaker: Nicola Normanno, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      14
      OCT 30, 2014 | 6:00 AM
      A platform for combining the results of WES and RNA-seq analysis
      A platform for combining the results of WES and RNA-seq analysis
      Cancer research is being revolutionized by targeted gene panels, whole exome sequencing (WES), whole genome sequencing (WGS), and transcriptome sequencing (RNA-Seq).Many analyses, such as...
      Speaker: Naomi Thomson
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
      OCT 30, 2014 | 6:00 AM
      Epigenetic Dysregulation in the Pathogenesis of Myeloproliferative Neoplasms
      Epigenetic Dysregulation in the Pathogenesis of Myeloproliferative...
      When the BCR/ABL1 fusion protein was identified in chronic myelogenous leukemia and the JAK2 V617F mutation was identified in patients with other myeloproliferative neoplasms (MPNs) such as p...
      Speaker: Kristin Landis-Piwowar, PhD, MLS
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      8
      OCT 29, 2014 | 3:00 PM
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
      Speaker: Michael J Mann, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      67
      OCT 29, 2014 | 3:00 PM
      Drug-tailored, efficacy-predictive and prognostic biomarker approaches for proper patient selection
      Drug-tailored, efficacy-predictive and prognostic biomarker approaches...
      Over the last decade we have witnessed tremendous advances in our understanding of the underlying molecular alterations in human cancer. This has stimulated excitement for our ability to deve...
      Speaker: Peter Blume-Jensen, MD, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      0
      OCT 29, 2014 | 3:00 PM
      Transforming the future of oncology with genomics
      Transforming the future of oncology with genomics
      Illumina next-generation sequencing (NGS) and microarray technologies are revolutionizing cancer research, enabling cancer variant discovery and detection and molecular monitoring. Join u...
      Speaker: Jennifer Stone, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      13
      OCT 29, 2014 | 1:30 PM
      Protein phosphatase 2A in cell survival upon metabolic stress
      Protein phosphatase 2A in cell survival upon metabolic stress
      Tumor cells often display fundamental changes in metabolism and increase their uptake of nutrients to meet the increased bioenergetic demands of proliferation. Glucose and glutamine are two m...
      Speaker: Mei Kong, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      10
      OCT 29, 2014 | 1:30 PM
      Metabolic therapy for the adjuvant treatment of malignant brain tumors
      Metabolic therapy for the adjuvant treatment of malignant brain...
      Human malignant glioma is a uniformly fatal disease, causing over 14,000 deaths in the US this year. Adults diagnosed with malignant brain tumors have a median survival of approximately 15 mo...
      Speaker: Adrienne C. Scheck, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      6
      OCT 29, 2014 | 1:30 PM
      PDX Tumor Models for Oncology Research and Preclinical Prediction
      PDX Tumor Models for Oncology Research and Preclinical Prediction
      Patient-derived xenograft (PDX) models can recapitulate patient tumor histopathology, mutational status, gene expression patterns, and drug response with remarkable fidelity. At The Jackson L...
      Speaker: Walter Ausserer, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      50
      OCT 29, 2014 | 12:00 PM
      Obesity, weight loss, and the microenvironment in basal-like breast cancer
      Obesity, weight loss, and the microenvironment in basal-like breast...
      Obesity is associated with an aggressive subtype of breast cancer called basal-like breast cancer (BBC). Using C3(1)-TAg mice, a genetically engineered mouse model that resembles human BBC, w...
      Speaker: Liza Makowski, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
      OCT 29, 2014 | 12:00 PM
      A Next-Gen Sequencing Software Workflow for Cancer Gene Panel Analysis
      A Next-Gen Sequencing Software Workflow for Cancer Gene Panel...
      DNASTAR offers an integrated suite of software for assembling and analyzing sequence data from all major next-generation sequencing platforms. The software supports a variety of key workflows...
      Speaker: Kerri Phillips
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      8
      OCT 29, 2014 | 12:00 PM
      Improving the Robustness and Reproducibility of Quantitative Proteomics
      Improving the Robustness and Reproducibility of Quantitative Proteomics
      Proteomics technology has improved dramatically over the last decade. The technology developments have largely been directed around instrument hardware, where instruments have been developed...
      Speaker: Michael MacCoss, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      6
      OCT 29, 2014 | 10:30 AM
      Learning from the Pointillists - Using Big Data Approaches to Embrace the Complexity of Cancer
      Learning from the Pointillists - Using Big Data Approaches to...
      The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
      Speaker: Kenneth Buetow, PhD, FACMI
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      14
      OCT 29, 2014 | 9:00 AM
      miRNA Biomarker Discovery: Technologies, workflows, and data analysis solutions for discovering your unique signature
      miRNA Biomarker Discovery: Technologies, workflows, and data analysis...
      Circulating miRNAs have great potential as biomarkers due to their aberrant expression in cancer and other diseases. However, miRNAs from body fluids are hard to obtain in amounts sufficient...
      Speaker: Jonathan Shaffer, PhD, MBA
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      18
      OCT 29, 2014 | 9:00 AM
      Reading and disrupting the histone code with chemical agents: making new tools to understand epigenetic methylation pathways in stem-like cancers
      Reading and disrupting the histone code with chemical agents:...
      Post-translational methylations play central roles in epigenetic gene regulation pathways that are central to stem cell regulation. Lysine methylations are turn-on switches for hundreds of di...
      Speaker: Fraser Hof, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      7
      OCT 29, 2014 | 9:00 AM
      What's wrong with biomarker development for cancer
      What's wrong with biomarker development for cancer
      Although robust and clinically meaningful biomarkers are key to achieving the current vision for precision (molecularly based), cancer medicine (patient stratification, early diagnosis, drug...
      Speaker: Anna Barker, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      10
      OCT 29, 2014 | 7:30 AM
      Antibody-based Proteomics: Fast-Tracking Molecular Diagnostics and Target Discovery in Oncology
      Antibody-based Proteomics: Fast-Tracking Molecular Diagnostics...
      The effective implementation of personalised cancer therapeutic regimens depends on the successful identification and translation of informative biomarkers to aid clinical decision-making. An...
      Speaker: Darran O'Connor, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      6
      OCT 29, 2014 | 7:30 AM
      Making Clinical NGS possible
      Making Clinical NGS possible
      Next-generation sequencing (NGS) has revolutionized extraction of genomic information, facilitating rapid advances in the fields of clinical research and molecular diagnostics. However, c...
      Speaker: Vikram Devgan, PhD, MBA
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
      OCT 29, 2014 | 7:30 AM
      Targeting the oncogene eIF4E in leukemia reveals a new form of drug resistance
      Targeting the oncogene eIF4E in leukemia reveals a new form of...
      The eukaryotic translation initiation factor eIF4E is an oncogene elevated in an estimated 30% of cancers. The traditional view is that eIF4E drives proliferation and survival by increasing t...
      Speaker: Katherine LB Borden, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      40
      OCT 29, 2014 | 6:00 AM
      Expanding the scope of RNA-Seq to archival FFPE samples
      Expanding the scope of RNA-Seq to archival FFPE samples
      As next-generation sequencing (NGS) platforms advance in their speed, ease-of-use, and cost-effectiveness, many translational researchers are transitioning from microarrays to RNA sequencing...
      Speaker: Kelli Bramlett, M.S.
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      4
      OCT 29, 2014 | 6:00 AM
      Nanotechnologies for Precision Medicine
      Nanotechnologies for Precision Medicine
      The modern era of Precision Medicine requires targeted delivery of molecular inhibitors that control key processes in disease pathways. PARP (Poly ADP Ribose Polymerase) plays a crucial role...
      Speaker: Srinivas (Sri) Sridhar, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      65
      OCT 28, 2014 | 8:00 AM
      The identification of single nucleotide and structural variants in gene sequencing
      The identification of single nucleotide and structural variants...
      The TLA Technology constitutes a paradigm shift in targeted next generation sequencing (NGS). The TLA technology uses the physical proximity of nucleotides within a locus of interest as the b...
      Speaker: Max van Min and Laurel Provencher
      Sponsored By: Revvity
      15
      OCT 24, 2014 | 12:00 PM
      What to Do About Flu in 2014
      What to Do About Flu in 2014
        Influenza is a major clinical and public health issue.  Rapid, accurate diagnostics for influenza have the potential to improve the efficacy of therapy, limit antibiotic over-use, conserve ...
      Speaker: Sheldon Campbell M.D. Ph.D. F.C.A.P.
      Sponsored By: Alere, Alere
      36
      OCT 16, 2014 | 8:00 AM
      Comprehensive Anti-doping Detection using the Q Exactive Orbitrap MS for Equine Urine Analysis
      Comprehensive Anti-doping Detection using the Q Exactive Orbitrap...
       Equine anti-doping analysis is a changing and dynamic field of science. The constant introduction of new drugs and biopharmaceuticals present challenges to the integrity of sports. Anti-dopi...
      Speaker: Scott D Stanley, PhD
      Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
      26
    OCT 30, 2014 | 7:30 AM
    Challenges in biomarker testing in non-small cell lung cancer research
    Challenges in biomarker testing in non-small cell lung cancer...
    Fusion genes play a central role in many cancer types. They have been used to classify malignancy, risk factors, disease prognosis, and companion diagnostic biomarkers for certain approved dr...
    Speaker: Nicola Normanno, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    14
    OCT 30, 2014 | 6:00 AM
    A platform for combining the results of WES and RNA-seq analysis
    A platform for combining the results of WES and RNA-seq analysis
    Cancer research is being revolutionized by targeted gene panels, whole exome sequencing (WES), whole genome sequencing (WGS), and transcriptome sequencing (RNA-Seq).Many analyses, such as...
    Speaker: Naomi Thomson
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    12
    OCT 30, 2014 | 6:00 AM
    Epigenetic Dysregulation in the Pathogenesis of Myeloproliferative Neoplasms
    Epigenetic Dysregulation in the Pathogenesis of Myeloproliferative...
    When the BCR/ABL1 fusion protein was identified in chronic myelogenous leukemia and the JAK2 V617F mutation was identified in patients with other myeloproliferative neoplasms (MPNs) such as p...
    Speaker: Kristin Landis-Piwowar, PhD, MLS
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    8
    OCT 29, 2014 | 3:00 PM
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
    Speaker: Michael J Mann, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    67
    OCT 29, 2014 | 3:00 PM
    Drug-tailored, efficacy-predictive and prognostic biomarker approaches for proper patient selection
    Drug-tailored, efficacy-predictive and prognostic biomarker approaches...
    Over the last decade we have witnessed tremendous advances in our understanding of the underlying molecular alterations in human cancer. This has stimulated excitement for our ability to deve...
    Speaker: Peter Blume-Jensen, MD, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    0
     
     
  • OCT 29, 2014 | 3:00 PM
    Transforming the future of oncology with genomics
    Transforming the future of oncology with genomics
    Illumina next-generation sequencing (NGS) and microarray technologies are revolutionizing cancer research, enabling cancer variant discovery and detection and molecular monitoring. Join u...
    Speaker: Jennifer Stone, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    13
    OCT 29, 2014 | 1:30 PM
    Protein phosphatase 2A in cell survival upon metabolic stress
    Protein phosphatase 2A in cell survival upon metabolic stress
    Tumor cells often display fundamental changes in metabolism and increase their uptake of nutrients to meet the increased bioenergetic demands of proliferation. Glucose and glutamine are two m...
    Speaker: Mei Kong, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    10
    OCT 29, 2014 | 1:30 PM
    Metabolic therapy for the adjuvant treatment of malignant brain tumors
    Metabolic therapy for the adjuvant treatment of malignant brain...
    Human malignant glioma is a uniformly fatal disease, causing over 14,000 deaths in the US this year. Adults diagnosed with malignant brain tumors have a median survival of approximately 15 mo...
    Speaker: Adrienne C. Scheck, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    6
    OCT 29, 2014 | 1:30 PM
    PDX Tumor Models for Oncology Research and Preclinical Prediction
    PDX Tumor Models for Oncology Research and Preclinical Prediction
    Patient-derived xenograft (PDX) models can recapitulate patient tumor histopathology, mutational status, gene expression patterns, and drug response with remarkable fidelity. At The Jackson L...
    Speaker: Walter Ausserer, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    50
    OCT 29, 2014 | 12:00 PM
    Obesity, weight loss, and the microenvironment in basal-like breast cancer
    Obesity, weight loss, and the microenvironment in basal-like breast...
    Obesity is associated with an aggressive subtype of breast cancer called basal-like breast cancer (BBC). Using C3(1)-TAg mice, a genetically engineered mouse model that resembles human BBC, w...
    Speaker: Liza Makowski, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    12
     
     
  • OCT 29, 2014 | 12:00 PM
    A Next-Gen Sequencing Software Workflow for Cancer Gene Panel Analysis
    A Next-Gen Sequencing Software Workflow for Cancer Gene Panel...
    DNASTAR offers an integrated suite of software for assembling and analyzing sequence data from all major next-generation sequencing platforms. The software supports a variety of key workflows...
    Speaker: Kerri Phillips
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    8
    OCT 29, 2014 | 12:00 PM
    Improving the Robustness and Reproducibility of Quantitative Proteomics
    Improving the Robustness and Reproducibility of Quantitative Proteomics
    Proteomics technology has improved dramatically over the last decade. The technology developments have largely been directed around instrument hardware, where instruments have been developed...
    Speaker: Michael MacCoss, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    6
    OCT 29, 2014 | 10:30 AM
    Learning from the Pointillists - Using Big Data Approaches to Embrace the Complexity of Cancer
    Learning from the Pointillists - Using Big Data Approaches to...
    The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
    Speaker: Kenneth Buetow, PhD, FACMI
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    14
    OCT 29, 2014 | 9:00 AM
    miRNA Biomarker Discovery: Technologies, workflows, and data analysis solutions for discovering your unique signature
    miRNA Biomarker Discovery: Technologies, workflows, and data analysis...
    Circulating miRNAs have great potential as biomarkers due to their aberrant expression in cancer and other diseases. However, miRNAs from body fluids are hard to obtain in amounts sufficient...
    Speaker: Jonathan Shaffer, PhD, MBA
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    18
    OCT 29, 2014 | 9:00 AM
    Reading and disrupting the histone code with chemical agents: making new tools to understand epigenetic methylation pathways in stem-like cancers
    Reading and disrupting the histone code with chemical agents:...
    Post-translational methylations play central roles in epigenetic gene regulation pathways that are central to stem cell regulation. Lysine methylations are turn-on switches for hundreds of di...
    Speaker: Fraser Hof, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    7
     
     
  • OCT 29, 2014 | 9:00 AM
    What's wrong with biomarker development for cancer
    What's wrong with biomarker development for cancer
    Although robust and clinically meaningful biomarkers are key to achieving the current vision for precision (molecularly based), cancer medicine (patient stratification, early diagnosis, drug...
    Speaker: Anna Barker, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    10
    OCT 29, 2014 | 7:30 AM
    Antibody-based Proteomics: Fast-Tracking Molecular Diagnostics and Target Discovery in Oncology
    Antibody-based Proteomics: Fast-Tracking Molecular Diagnostics...
    The effective implementation of personalised cancer therapeutic regimens depends on the successful identification and translation of informative biomarkers to aid clinical decision-making. An...
    Speaker: Darran O'Connor, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    6
    OCT 29, 2014 | 7:30 AM
    Making Clinical NGS possible
    Making Clinical NGS possible
    Next-generation sequencing (NGS) has revolutionized extraction of genomic information, facilitating rapid advances in the fields of clinical research and molecular diagnostics. However, c...
    Speaker: Vikram Devgan, PhD, MBA
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    12
    OCT 29, 2014 | 7:30 AM
    Targeting the oncogene eIF4E in leukemia reveals a new form of drug resistance
    Targeting the oncogene eIF4E in leukemia reveals a new form of...
    The eukaryotic translation initiation factor eIF4E is an oncogene elevated in an estimated 30% of cancers. The traditional view is that eIF4E drives proliferation and survival by increasing t...
    Speaker: Katherine LB Borden, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    40
    OCT 29, 2014 | 6:00 AM
    Expanding the scope of RNA-Seq to archival FFPE samples
    Expanding the scope of RNA-Seq to archival FFPE samples
    As next-generation sequencing (NGS) platforms advance in their speed, ease-of-use, and cost-effectiveness, many translational researchers are transitioning from microarrays to RNA sequencing...
    Speaker: Kelli Bramlett, M.S.
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    4
     
     
  • OCT 29, 2014 | 6:00 AM
    Nanotechnologies for Precision Medicine
    Nanotechnologies for Precision Medicine
    The modern era of Precision Medicine requires targeted delivery of molecular inhibitors that control key processes in disease pathways. PARP (Poly ADP Ribose Polymerase) plays a crucial role...
    Speaker: Srinivas (Sri) Sridhar, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    65
    OCT 28, 2014 | 8:00 AM
    The identification of single nucleotide and structural variants in gene sequencing
    The identification of single nucleotide and structural variants...
    The TLA Technology constitutes a paradigm shift in targeted next generation sequencing (NGS). The TLA technology uses the physical proximity of nucleotides within a locus of interest as the b...
    Speaker: Max van Min and Laurel Provencher
    Sponsored By: Revvity
    15
    OCT 24, 2014 | 12:00 PM
    What to Do About Flu in 2014
    What to Do About Flu in 2014
      Influenza is a major clinical and public health issue.  Rapid, accurate diagnostics for influenza have the potential to improve the efficacy of therapy, limit antibiotic over-use, conserve ...
    Speaker: Sheldon Campbell M.D. Ph.D. F.C.A.P.
    Sponsored By: Alere, Alere
    36
    OCT 16, 2014 | 8:00 AM
    Comprehensive Anti-doping Detection using the Q Exactive Orbitrap MS for Equine Urine Analysis
    Comprehensive Anti-doping Detection using the Q Exactive Orbitrap...
     Equine anti-doping analysis is a changing and dynamic field of science. The constant introduction of new drugs and biopharmaceuticals present challenges to the integrity of sports. Anti-dopi...
    Speaker: Scott D Stanley, PhD
    Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
    26
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