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    Structural Biology

    Structural biology is a branch of molecular biology, biochemistry, and biophysics concerned with the molecular structure of biological macromolecules, how they acquire the structures they have, and how alterations in their structures affect their function.

    Webinars

    • APR 20, 2021 | 12:00 AM
      The Structure, Function, and Evolution of Human Chromosome 8
      The Structure, Function, and Evolution of Human Chromosome 8
      The complete assembly of each human chromosome is essential for understanding human biology and evolution. Using complementary long-read sequencing technologies, we complete the first linear...
      Speaker: Glennis Logsdon, PhD
      Presented at: Genetics Week Virtual Event Series 2021
      2
      APR 20, 2021 | 12:00 AM
      X Chromosome Factors that Contribute to Sex Differences in Disease
      X Chromosome Factors that Contribute to Sex Differences in Disease
      Many diseases show sex differences in incidence or progression, suggesting that one sex has inherent biological factors that protect from or exacerbate disease. Historically the root causes...
      Speaker: Arthur P. Arnold, PhD
      Presented at: Genetics Week Virtual Event Series 2021
      3
      FEB 24, 2021 | 1:30 PM
      Roundtable Panel Presentation: Recent Trends in Screening GPCRs
      Roundtable Panel Presentation: Recent Trends in Screening GPCRs
      G protein-coupled receptors (GPCRs) are among the most intensively studied drug targets, and account for about ~34% of all drugs approved by the FDA. Examples of drugs targeting GPCRs includ...
      Speaker: Annette Gilchrist, PhD , Professor Kevin Pfleger, MA, PhD, FBPhS , Juan José Fung, PhD , Aarti Kawatkar , Yamina A. Berchiche, PhD , Ajay Yekkirala, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2021
      1
      FEB 24, 2021 | 10:00 AM
      Biosafety Enclosures and the Automated Lab: Steps for Success
      Biosafety Enclosures and the Automated Lab: Steps for Success
      DATE: February 24, 2021 TIME: 10am PST Automated lab instruments such as liquid handlers and cell sorters are increasingly common in all types of laboratories, driving fast results for labor...
      Speaker: David Wasescha , Simon Fogarty
      Sponsored By: Labconco
      15
      FEB 24, 2021 | 6:00 AM
      Introducing GenScript's DNA-Encoded Chemical Library Kit - GenDECL
      Introducing GenScript's DNA-Encoded Chemical Library Kit - GenDECL
      GenScript’s new DNA Encoded Chemical Library (DECL) kit will revolutionize your pharmaceutical hit discovery and chemical biology research. In partnership with a leading technology exp...
      Speaker: Rouba Najjar, MBA
      Presented at: Drug Discovery & Development Virtual Event Series 2021
      Sponsored By: GenScript
      2
      FEB 09, 2021 | 9:00 AM
      Development and analytical validation of prognostic biomarkers for metastasis
      Development and analytical validation of prognostic biomarkers...
      Date: February 9, 2020 Time: 9:00am (PST), 12:00pm (EST) 90% of breast cancer mortality is caused by distant metastasis, a process that involves both dissemination of cancer cells to distant...
      Speaker: David Entenberg, PhD
      Sponsored By: Visiopharm®
      20
      JAN 26, 2021 | 8:00 AM
      High-throughput CRISPR editing using the Onyxâ„¢ platform identifies essential residues in proteins
      High-throughput CRISPR editing using the Onyxâ„¢ platform identifies...
      Date: January 26, 2021 Time: 9:00am (PST), 12:00pm (EST) Over the past years, CRISPR/Cas genome editing has quickly become the method of choice for genetic manipulation, owing to its ease-of...
      Speaker: Liselot Dewachter, PhD , Laura Klitten, Ph.D.
      Sponsored By: Inscripta
      13 2
      JAN 21, 2021 | 8:00 AM
      Critical reagent characterization for regulated bioassays accelerated by Uncle
      Critical reagent characterization for regulated bioassays accelerated...
      Date: January 21, 2021 Time: 8:00am (PST), 11:00am (EST) Today, critical reagent characterization is a key component in the overall workflow to establish robust ligand binding assays (e.g.,...
      Speaker: Ron Bowsher , Adam Kinne , Kevin Lance, Ph.D.
      Sponsored By: Unchained Labs
      6
      DEC 17, 2020 | 9:00 AM
      Advancing Cell Biology with Cryo-Correlative Microscopy
      Advancing Cell Biology with Cryo-Correlative Microscopy
      Date: December 17, 2020 Time: 9:00am (PST), 12:00pm (EST) Correlative light and electron microscopy (CLEM) advances biological discoveries by merging different microscopes and imaging moda...
      Speaker: Elizabeth Wright, Ph.D. , Jae Yang, Ph.D. , Bryan Sibert, Ph.D. , Joseph Kim
      Sponsored By: Leica Microsystems, Alveole
      13 2
      NOV 19, 2020 | 9:00 AM
      From Protein Structures to Drug Discovery: Novel therapeutic opportunities.
      From Protein Structures to Drug Discovery: Novel therapeutic opportunities.
      DATE: November 19, 2020 TIME: 9:00am PT, 12am ET Knowledge of the three-dimensional structure of therapeutically relevant targets has become an essential step in the pipeline of drug discove...
      Speaker: Amal Hassan Ali
      Sponsored By: Thermo Fisher Scientific
      16 1
      NOV 10, 2020 | 9:00 AM
      Fast and reliable Gene Synthesis for optimized protein expression
      Fast and reliable Gene Synthesis for optimized protein expression
      DATE: November 10, 2020 TIME: 9:00am PT, 12am ET Gene Synthesis ensures fast access to nearly any DNA sequence, regardless its origin or complexity. Its reliability, flexibility and fast tur...
      Speaker: Claudia Chiocchini
      Sponsored By: Thermo Fisher Scientific
      19
      OCT 15, 2020 | 9:00 AM
      Evaluating the Kidney-Chip for Transporter-Mediated Drug-Drug Interactions Applications
      Evaluating the Kidney-Chip for Transporter-Mediated Drug-Drug...
      Date: October 15, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Renal transporters play an important role in potential clinical drug-drug interactions (DDIs) as highlighted in the FDA, EMA and PMDA...
      Speaker: Steven Anderson, PhD , Kyung-Jin Jang, PhD , Donald McKenzie, PhD
      Sponsored By: Emulate
      9
      OCT 08, 2020 | 9:00 AM
      The Spatiotemporal Organization, Dynamics, and Function of Virus Replication Centers during Murine Polyomavirus Infection
      The Spatiotemporal Organization, Dynamics, and Function of Virus...
      Date: October 8, 2020 Time: 9:00am (PTD), 12:00pm (EDT), 5:00pm (GMT) Small DNA viruses require both host DNA replication and repair factors for their replication. The host cell replication...
      Speaker: Douglas Peters, PhD , Alan Mullan, PhD
      Sponsored By: Andor
      8
      OCT 08, 2020 | 12:00 AM
      Transcriptome analysis of breast cancer clinical specimens with long-read sequencer
      Transcriptome analysis of breast cancer clinical specimens with...
      Changes in transcriptional regulation are thought to be one of the key drivers of carcinogenesis. Although next-generation sequencer revolutionized transcriptome analysis, there are limitati...
      Speaker: Masahito Kawazu, MD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      1
      OCT 08, 2020 | 12:00 AM
      We Don't Care What You Know Until You Show Us That You Care': Characterizing Access to Healthcare among Black, Hispanic and White Cancer Survivors
      We Don't Care What You Know Until You Show Us That You Care':...
      Background: Healthcare access (HCA) encompasses five important dimensions: Affordability, Availability, Accessibility, Accommodation and Acceptability. Published studies of cancer typically...
      Speaker: Tomi Akinyemiju, PhD, MS
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      2
      SEP 30, 2020 | 12:00 AM
      Measuring Outcomes of CRISPR Experiments & Leveraging Cas9 for Targeted Sequencing
      Measuring Outcomes of CRISPR Experiments & Leveraging Cas9 for...
      CRISPR experiments are a powerful tool which are easy to carry out, however it is more difficult to determine the outcome of these experiments, and to ensure that only the desired targets we...
      Speaker: Jonas Korlach, PhD
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 28, 2020 | 5:00 PM
      Applying a single-cell GPS to discover novel spatial biomarkers in FFPE tissues
      Applying a single-cell GPS to discover novel spatial biomarkers...
      Date: September 28, 2020 Time: 5:00pm (PDT), 8:00am (HKT), 9:00am (JST) Although there have been dramatic advances in the field of single-cell sequencing, current methods cannot be applied t...
      Speaker: Kohta Miyawaki, MD, PhD , Aaron Mayer, PhD , Oliver Braubach, Ph.D.
      Sponsored By: Akoya Biosciences
      12
      SEP 23, 2020 | 4:30 PM
      Anatomy of a nucleic acid sample preparation
      Anatomy of a nucleic acid sample preparation
      There are many methods of nucleic acid isolation. Each technology offers different approaches of purification of the template. However, it is important to control carry over of “proces...
      Speaker: Katherine Mechling
      Presented at: Cell Biology Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      2 1
      SEP 23, 2020 | 3:00 PM
      Beyond the Culture Flask: How Membrane- and Microfluidic-based Platforms can create more Physiologically Relevant Tissue Culture Systems
      Beyond the Culture Flask: How Membrane- and Microfluidic-based...
      For more than a century, breakthroughs in biological sciences have relied on the ability to study cells outside of respective organisms. While majority of cell culturing is still performed u...
      Speaker: Jun Park, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      1
      SEP 23, 2020 | 1:30 PM
      Keynote Presentation: Starting at the source: tissue extracellular vesicles and Alzheimer's disease
      Keynote Presentation: Starting at the source: tissue extracellular...
      Extracellular vesicles (EVs) are lipid bilayer-delimited pieces of cells that are released from the plasma membrane as "ectosomes" and from the endosomal system as "exosomes.&...
      Speaker: Kenneth W. Witwer, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 23, 2020 | 12:00 PM
      Keynote Presentation: Sorting out the mechanisms of endocytic recycling
      Keynote Presentation: Sorting out the mechanisms of endocytic...
      Extracellular ligands bind to receptors on the cell surface leading to receptor internalization. Once internalized into small vesicles, the vesicles fuse with an organelle known as the sorti...
      Speaker: Steve Caplan, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 23, 2020 | 10:30 AM
      iPSC- and patient- derived intestinal organoids for gastrointestinal research
      iPSC- and patient- derived intestinal organoids for gastrointestinal...
      Intestinal organoids are self-organizing, 3D structures derived from either pluripotent stem cells or from primary tissues with the abiltiy to recapitulate some of the spatial architecture a...
      Speaker: Kevin Su
      Presented at: Cell Biology Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      2
      SEP 23, 2020 | 10:00 AM
      Sepsis Diagnosis: Role of Data Analytics in Specimen Collection, Processing and Laboratory Workflow
      Sepsis Diagnosis: Role of Data Analytics in Specimen Collection,...
      DATE: September 23, 2020 TIME: 10:00am PT, 1:00pm ET Diagnostics, particularly blood cultures, play a key role in sepsis diagnosis. Best practices are well-known for collection, transport, a...
      Speaker: Patrick Murray, PhD
      Sponsored By: BD
      12 1
      SEP 23, 2020 | 9:00 AM
      Keynote Presentation: Extracellular vesicles in Regenerative Medicine
      Keynote Presentation: Extracellular vesicles in Regenerative Medicine
      Extracellular vesicles (EVs) are nanosized vesicles containing active proteins, lipids, and different types of genetic material such as non coding RNA species, related to the characteristics...
      Speaker: Benedetta Bussolati, MD, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      2
    APR 20, 2021 | 12:00 AM
    The Structure, Function, and Evolution of Human Chromosome 8
    The Structure, Function, and Evolution of Human Chromosome 8
    The complete assembly of each human chromosome is essential for understanding human biology and evolution. Using complementary long-read sequencing technologies, we complete the first linear...
    Speaker: Glennis Logsdon, PhD
    Presented at: Genetics Week Virtual Event Series 2021
    2
    APR 20, 2021 | 12:00 AM
    X Chromosome Factors that Contribute to Sex Differences in Disease
    X Chromosome Factors that Contribute to Sex Differences in Disease
    Many diseases show sex differences in incidence or progression, suggesting that one sex has inherent biological factors that protect from or exacerbate disease. Historically the root causes...
    Speaker: Arthur P. Arnold, PhD
    Presented at: Genetics Week Virtual Event Series 2021
    3
    FEB 24, 2021 | 1:30 PM
    Roundtable Panel Presentation: Recent Trends in Screening GPCRs
    Roundtable Panel Presentation: Recent Trends in Screening GPCRs
    G protein-coupled receptors (GPCRs) are among the most intensively studied drug targets, and account for about ~34% of all drugs approved by the FDA. Examples of drugs targeting GPCRs includ...
    Speaker: Annette Gilchrist, PhD , Professor Kevin Pfleger, MA, PhD, FBPhS , Juan José Fung, PhD , Aarti Kawatkar , Yamina A. Berchiche, PhD , Ajay Yekkirala, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2021
    1
    FEB 24, 2021 | 10:00 AM
    Biosafety Enclosures and the Automated Lab: Steps for Success
    Biosafety Enclosures and the Automated Lab: Steps for Success
    DATE: February 24, 2021 TIME: 10am PST Automated lab instruments such as liquid handlers and cell sorters are increasingly common in all types of laboratories, driving fast results for labor...
    Speaker: David Wasescha , Simon Fogarty
    Sponsored By: Labconco
    15
    FEB 24, 2021 | 6:00 AM
    Introducing GenScript's DNA-Encoded Chemical Library Kit - GenDECL
    Introducing GenScript's DNA-Encoded Chemical Library Kit - GenDECL
    GenScript’s new DNA Encoded Chemical Library (DECL) kit will revolutionize your pharmaceutical hit discovery and chemical biology research. In partnership with a leading technology exp...
    Speaker: Rouba Najjar, MBA
    Presented at: Drug Discovery & Development Virtual Event Series 2021
    Sponsored By: GenScript
    2
     
     
  • FEB 09, 2021 | 9:00 AM
    Development and analytical validation of prognostic biomarkers for metastasis
    Development and analytical validation of prognostic biomarkers...
    Date: February 9, 2020 Time: 9:00am (PST), 12:00pm (EST) 90% of breast cancer mortality is caused by distant metastasis, a process that involves both dissemination of cancer cells to distant...
    Speaker: David Entenberg, PhD
    Sponsored By: Visiopharm®
    20
    JAN 26, 2021 | 8:00 AM
    High-throughput CRISPR editing using the Onyxâ„¢ platform identifies essential residues in proteins
    High-throughput CRISPR editing using the Onyxâ„¢ platform identifies...
    Date: January 26, 2021 Time: 9:00am (PST), 12:00pm (EST) Over the past years, CRISPR/Cas genome editing has quickly become the method of choice for genetic manipulation, owing to its ease-of...
    Speaker: Liselot Dewachter, PhD , Laura Klitten, Ph.D.
    Sponsored By: Inscripta
    13 2
    JAN 21, 2021 | 8:00 AM
    Critical reagent characterization for regulated bioassays accelerated by Uncle
    Critical reagent characterization for regulated bioassays accelerated...
    Date: January 21, 2021 Time: 8:00am (PST), 11:00am (EST) Today, critical reagent characterization is a key component in the overall workflow to establish robust ligand binding assays (e.g.,...
    Speaker: Ron Bowsher , Adam Kinne , Kevin Lance, Ph.D.
    Sponsored By: Unchained Labs
    6
    DEC 17, 2020 | 9:00 AM
    Advancing Cell Biology with Cryo-Correlative Microscopy
    Advancing Cell Biology with Cryo-Correlative Microscopy
    Date: December 17, 2020 Time: 9:00am (PST), 12:00pm (EST) Correlative light and electron microscopy (CLEM) advances biological discoveries by merging different microscopes and imaging moda...
    Speaker: Elizabeth Wright, Ph.D. , Jae Yang, Ph.D. , Bryan Sibert, Ph.D. , Joseph Kim
    Sponsored By: Leica Microsystems, Alveole
    13 2
    NOV 19, 2020 | 9:00 AM
    From Protein Structures to Drug Discovery: Novel therapeutic opportunities.
    From Protein Structures to Drug Discovery: Novel therapeutic opportunities.
    DATE: November 19, 2020 TIME: 9:00am PT, 12am ET Knowledge of the three-dimensional structure of therapeutically relevant targets has become an essential step in the pipeline of drug discove...
    Speaker: Amal Hassan Ali
    Sponsored By: Thermo Fisher Scientific
    16 1
     
     
  • NOV 10, 2020 | 9:00 AM
    Fast and reliable Gene Synthesis for optimized protein expression
    Fast and reliable Gene Synthesis for optimized protein expression
    DATE: November 10, 2020 TIME: 9:00am PT, 12am ET Gene Synthesis ensures fast access to nearly any DNA sequence, regardless its origin or complexity. Its reliability, flexibility and fast tur...
    Speaker: Claudia Chiocchini
    Sponsored By: Thermo Fisher Scientific
    19
    OCT 15, 2020 | 9:00 AM
    Evaluating the Kidney-Chip for Transporter-Mediated Drug-Drug Interactions Applications
    Evaluating the Kidney-Chip for Transporter-Mediated Drug-Drug...
    Date: October 15, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Renal transporters play an important role in potential clinical drug-drug interactions (DDIs) as highlighted in the FDA, EMA and PMDA...
    Speaker: Steven Anderson, PhD , Kyung-Jin Jang, PhD , Donald McKenzie, PhD
    Sponsored By: Emulate
    9
    OCT 08, 2020 | 9:00 AM
    The Spatiotemporal Organization, Dynamics, and Function of Virus Replication Centers during Murine Polyomavirus Infection
    The Spatiotemporal Organization, Dynamics, and Function of Virus...
    Date: October 8, 2020 Time: 9:00am (PTD), 12:00pm (EDT), 5:00pm (GMT) Small DNA viruses require both host DNA replication and repair factors for their replication. The host cell replication...
    Speaker: Douglas Peters, PhD , Alan Mullan, PhD
    Sponsored By: Andor
    8
    OCT 08, 2020 | 12:00 AM
    Transcriptome analysis of breast cancer clinical specimens with long-read sequencer
    Transcriptome analysis of breast cancer clinical specimens with...
    Changes in transcriptional regulation are thought to be one of the key drivers of carcinogenesis. Although next-generation sequencer revolutionized transcriptome analysis, there are limitati...
    Speaker: Masahito Kawazu, MD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    1
    OCT 08, 2020 | 12:00 AM
    We Don't Care What You Know Until You Show Us That You Care': Characterizing Access to Healthcare among Black, Hispanic and White Cancer Survivors
    We Don't Care What You Know Until You Show Us That You Care':...
    Background: Healthcare access (HCA) encompasses five important dimensions: Affordability, Availability, Accessibility, Accommodation and Acceptability. Published studies of cancer typically...
    Speaker: Tomi Akinyemiju, PhD, MS
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    2
     
     
  • SEP 30, 2020 | 12:00 AM
    Measuring Outcomes of CRISPR Experiments & Leveraging Cas9 for Targeted Sequencing
    Measuring Outcomes of CRISPR Experiments & Leveraging Cas9 for...
    CRISPR experiments are a powerful tool which are easy to carry out, however it is more difficult to determine the outcome of these experiments, and to ensure that only the desired targets we...
    Speaker: Jonas Korlach, PhD
    Presented at: CRISPR Virtual Event Series 2020
    1
    SEP 28, 2020 | 5:00 PM
    Applying a single-cell GPS to discover novel spatial biomarkers in FFPE tissues
    Applying a single-cell GPS to discover novel spatial biomarkers...
    Date: September 28, 2020 Time: 5:00pm (PDT), 8:00am (HKT), 9:00am (JST) Although there have been dramatic advances in the field of single-cell sequencing, current methods cannot be applied t...
    Speaker: Kohta Miyawaki, MD, PhD , Aaron Mayer, PhD , Oliver Braubach, Ph.D.
    Sponsored By: Akoya Biosciences
    12
    SEP 23, 2020 | 4:30 PM
    Anatomy of a nucleic acid sample preparation
    Anatomy of a nucleic acid sample preparation
    There are many methods of nucleic acid isolation. Each technology offers different approaches of purification of the template. However, it is important to control carry over of “proces...
    Speaker: Katherine Mechling
    Presented at: Cell Biology Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    2 1
    SEP 23, 2020 | 3:00 PM
    Beyond the Culture Flask: How Membrane- and Microfluidic-based Platforms can create more Physiologically Relevant Tissue Culture Systems
    Beyond the Culture Flask: How Membrane- and Microfluidic-based...
    For more than a century, breakthroughs in biological sciences have relied on the ability to study cells outside of respective organisms. While majority of cell culturing is still performed u...
    Speaker: Jun Park, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    1
    SEP 23, 2020 | 1:30 PM
    Keynote Presentation: Starting at the source: tissue extracellular vesicles and Alzheimer's disease
    Keynote Presentation: Starting at the source: tissue extracellular...
    Extracellular vesicles (EVs) are lipid bilayer-delimited pieces of cells that are released from the plasma membrane as "ectosomes" and from the endosomal system as "exosomes.&...
    Speaker: Kenneth W. Witwer, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    1
     
     
  • SEP 23, 2020 | 12:00 PM
    Keynote Presentation: Sorting out the mechanisms of endocytic recycling
    Keynote Presentation: Sorting out the mechanisms of endocytic...
    Extracellular ligands bind to receptors on the cell surface leading to receptor internalization. Once internalized into small vesicles, the vesicles fuse with an organelle known as the sorti...
    Speaker: Steve Caplan, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    1
    SEP 23, 2020 | 10:30 AM
    iPSC- and patient- derived intestinal organoids for gastrointestinal research
    iPSC- and patient- derived intestinal organoids for gastrointestinal...
    Intestinal organoids are self-organizing, 3D structures derived from either pluripotent stem cells or from primary tissues with the abiltiy to recapitulate some of the spatial architecture a...
    Speaker: Kevin Su
    Presented at: Cell Biology Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    2
    SEP 23, 2020 | 10:00 AM
    Sepsis Diagnosis: Role of Data Analytics in Specimen Collection, Processing and Laboratory Workflow
    Sepsis Diagnosis: Role of Data Analytics in Specimen Collection,...
    DATE: September 23, 2020 TIME: 10:00am PT, 1:00pm ET Diagnostics, particularly blood cultures, play a key role in sepsis diagnosis. Best practices are well-known for collection, transport, a...
    Speaker: Patrick Murray, PhD
    Sponsored By: BD
    12 1
    SEP 23, 2020 | 9:00 AM
    Keynote Presentation: Extracellular vesicles in Regenerative Medicine
    Keynote Presentation: Extracellular vesicles in Regenerative Medicine
    Extracellular vesicles (EVs) are nanosized vesicles containing active proteins, lipids, and different types of genetic material such as non coding RNA species, related to the characteristics...
    Speaker: Benedetta Bussolati, MD, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    2
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