Surgery: The branch of medicine that employs operations in the treatment of disease or injury. Surgery can involve cutting, abrading, suturing, or otherwise physically changing body tissues and organs. It uses uses operative manual and instrumental techniques on a patient to investigate or treat a pathological condition such as a disease or injury, to help improve bodily function or appearance or to repair unwanted ruptured areas.
DATE: February 9, 2017TIME: 9:00am PT, 12:00pm ETThe last few years have led to great progress in Chile in terms of laboratory animal care and use. There are new legal mandates to prote...
DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETIn rabbits, buprenorphine instant release (IR) is commonly used to alleviate pain, especially in surgical models. However, maintenan...
DATE: February 8, 2017TIME: 12:00pm PT, 3:00pm ETIn-vivo surgical models are becoming more prevalent and more critical to the drug development process. As the vast majority of ind...
DATE: February 8, 2017TIME: 7:30am PT, 10:30am ETMany of us who believe in the importance of aseptic rodent surgery have lived through the frustration of trying to implement rodent asep...
DATE: December 7, 2016TIME: 8:00am PT, 11:00am ET1,25-dihydroxyvitamin D (1,25[OH]2D) is the active, hormonal form of vitamin D. It is produced from its precursor (vitamin D) by two hyd...
DATE: December 1, 2016TIME: 8:00 AM PT, 11:00 AM ETPreclinical imaging enables the measurement and assessment of biological processes in vivo utilizing technologies such as biolum...
Over the past 6 years, a number of agents, all mechanistically different, have been approved with a statistically significant survival benefit as monotherapy for treatment of metastatic castr...
Melanoma arises in the pigment producing cells (melanocytes) and is the deadliest of the skin cancers. It accounts for nearly 200,000 new cases of cancer each year worldwide and in the U.S. o...
The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
A major challenge for the clinical application of pluripotent stem cell therapy for neurodegenerative diseases is large-scale manufacturing and cryopreservation of neurons and glia that can b...
Cataract, or vision loss due to clouding of the eye’s lens, is a large and costly international problem. Over 80 million people currently have low vision due to cataract. Cataracts can ...
We have been developing methods to target drugs specifically to pathologic cells, thereby avoiding collateral toxicity to healthy cells. In the case of cancer, we have exploited up-regulation...
Schizophrenia, depression, bipolar disorder are all uniquely human conditions. Psychiatric conditions include alterations in several different and overlapping domains (NIMH RDoC). Each...
Schizophrenia (Sz) is a major mental disorder that affects ~1% of the population. Although traditional models of Sz focused on dopaminergic dysfunction, newer models increasingly implic...
In this presentation, Arvid Carlsson, who was awarded the Nobel prize in 2000 for his discovery of the transmitter role of dopamine, will be interviewed by Elias Eriksson. The following aspec...
Impulse control disorders (ICDs), also known as behavioural addictions, are common in the general population and can have marked consequences. ICDs can also commonly occur with exposure...
Innovation in Psychopharmacology is Dead. Long Live Innovation in Psychopharmacology! What’s going on in our field? Priorities of Big Pharma shifting away fr...
We routinely face decisions requiring evaluation and choice of different actions may or may not yield different types of rewards. These situations trigger competitive decision biases that ref...
Working with animals carries legal, scientific and ethical responsibilities. These responsibilities merge as we strive to humanely use the least number of animals necessary to provide t...
The use of laboratory animals requires education and training of persons who are to design and/or perform animal experiments. It is essential for these persons to practice various procedures...
Cancer-derived extracellular vesicles (EVs) play an important role in cancer progression and metastasis. They can be identified in biological fluids thus providing appealing candidates for no...
Stage IV melanoma carried a 24 month life expectancy three short years ago. That is what T.J. Sharpe’s first oncologist told him he was facing, after a visit to the ER for a fever turne...
DATE: February 9, 2017TIME: 9:00am PT, 12:00pm ETThe last few years have led to great progress in Chile in terms of laboratory animal care and use. There are new legal mandates to prote...
DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETIn rabbits, buprenorphine instant release (IR) is commonly used to alleviate pain, especially in surgical models. However, maintenan...
DATE: February 8, 2017TIME: 12:00pm PT, 3:00pm ETIn-vivo surgical models are becoming more prevalent and more critical to the drug development process. As the vast majority of ind...
DATE: February 8, 2017TIME: 7:30am PT, 10:30am ETMany of us who believe in the importance of aseptic rodent surgery have lived through the frustration of trying to implement rodent asep...
DATE: December 7, 2016TIME: 8:00am PT, 11:00am ET1,25-dihydroxyvitamin D (1,25[OH]2D) is the active, hormonal form of vitamin D. It is produced from its precursor (vitamin D) by two hyd...
DATE: December 1, 2016TIME: 8:00 AM PT, 11:00 AM ETPreclinical imaging enables the measurement and assessment of biological processes in vivo utilizing technologies such as biolum...
Over the past 6 years, a number of agents, all mechanistically different, have been approved with a statistically significant survival benefit as monotherapy for treatment of metastatic castr...
Melanoma arises in the pigment producing cells (melanocytes) and is the deadliest of the skin cancers. It accounts for nearly 200,000 new cases of cancer each year worldwide and in the U.S. o...
The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
A major challenge for the clinical application of pluripotent stem cell therapy for neurodegenerative diseases is large-scale manufacturing and cryopreservation of neurons and glia that can b...
Cataract, or vision loss due to clouding of the eye’s lens, is a large and costly international problem. Over 80 million people currently have low vision due to cataract. Cataracts can ...
We have been developing methods to target drugs specifically to pathologic cells, thereby avoiding collateral toxicity to healthy cells. In the case of cancer, we have exploited up-regulation...
Schizophrenia, depression, bipolar disorder are all uniquely human conditions. Psychiatric conditions include alterations in several different and overlapping domains (NIMH RDoC). Each...
Schizophrenia (Sz) is a major mental disorder that affects ~1% of the population. Although traditional models of Sz focused on dopaminergic dysfunction, newer models increasingly implic...
In this presentation, Arvid Carlsson, who was awarded the Nobel prize in 2000 for his discovery of the transmitter role of dopamine, will be interviewed by Elias Eriksson. The following aspec...
Impulse control disorders (ICDs), also known as behavioural addictions, are common in the general population and can have marked consequences. ICDs can also commonly occur with exposure...
Innovation in Psychopharmacology is Dead. Long Live Innovation in Psychopharmacology! What’s going on in our field? Priorities of Big Pharma shifting away fr...
We routinely face decisions requiring evaluation and choice of different actions may or may not yield different types of rewards. These situations trigger competitive decision biases that ref...
Working with animals carries legal, scientific and ethical responsibilities. These responsibilities merge as we strive to humanely use the least number of animals necessary to provide t...
The use of laboratory animals requires education and training of persons who are to design and/or perform animal experiments. It is essential for these persons to practice various procedures...
Cancer-derived extracellular vesicles (EVs) play an important role in cancer progression and metastasis. They can be identified in biological fluids thus providing appealing candidates for no...
Stage IV melanoma carried a 24 month life expectancy three short years ago. That is what T.J. Sharpe’s first oncologist told him he was facing, after a visit to the ER for a fever turne...
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