Transcriptomics: is the study of the transcriptome-the complete set of RNA transcripts that are produced by the genome, under specific circumstances or in a specific cell-using high-throughput methods, such as microarray analysis.
DATE: January 30, 2018TIME: 9:00AM PST, 12:00PM ESTInfectious disease surveillance and monitoring is critical in settings where disease outbreaks and antibiotic resistance can dramatica...
DATE: November 15, 2017TIME: 09:00am PST, 12:00pm ESTMicroRNAs (miRNA) are a class of small non-coding RNAs (approximately 21 nt long) that bind complementary sequences in target mRNAs...
Currently, prostate cancer is the second leading cause of death from cancer in North America, the most frequent malignancy in men from all ethnicities, surpassing lung cancer. Prostate tumors...
DATE: October 17, 2017TIME: 08:00am PDT, 11:00am EDTResearching and understanding the mechanisms of drug resistance are essential to determine therapies that are more effective on an in...
Acral lentiginous melanoma (ALM) is a rare sun-shielded melanoma subtype associated with worse survival than cutaneous melanoma (CM), a more common form of skin cancer linked to exposure to u...
Nanopore sequencing has enormous potential for application to cancer, but specifically offers advantages into two main arenas, epigenetics and structural variation. Methylation is well-known...
DATE: September 6, 2017TIME: 9:00AM PST, 12:00PM ET The era of using extracellular vesicles (EVs) and exosomes for regenerative medicine applications in the clinic is here. We...
Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (iPSCs) as well as engineered heart muscles offer great potential for regenerative applications by CM transplantation, f...
Therapeutic application of pluripotent stem (PS) cell-derived products represents the ultimate goal of stem cell research. In order to apply this technology to patients, it is fundamental to ...
In the last years, progress has been made regarding the differentiation of human pluripotent stem cells into neural stem cells and astrocytes, growing into neurospheres and cerebral organoids...
As reprogramming methodologies have become more reliable and efficient, corresponding improvements were needed in the characterization workflow as well; specifically in terms of the speed, ef...
Disease-specific human pluripotent stem cells (hPSCs) represent a new chance to unravel cellular and molecular mechanisms of neurological diseases. Along this line, we were among the first to...
DATE: June 28, 2017TIME: 9:00AM PDT, 12:00PM EDT, 6:00PM CESTMany RNA binding proteins (RBPs) regulate the selection of alternative polyA sites. To understand their regulatory principle...
DATE: June 27, 2017TIME: 8:00am PT, 11:00am ETThe purpose of this study is to identify genetic variants that influence cellular responses, and patterns of M.tb infection and growth in h...
Unfortunately due to technical issues this webinar has been delayed until June 26th. If you are unable to make the new time, it will be available on demand for you to view.DATE: June 26,...
DATE: June 8, 2017TIME: 10:00AM PDT, 1:00PM EDT, 7:00PM CESTAlzheimer’s Disease (AD) is the result of complex interactions between risk factors that cause pleiotropic changes in m...
In this seminar, I will discuss issues in transcriptome analysis. I will first talk about core aspects - how we analyze the activity patterns of genes in model organisms and humans. I will fo...
When studying the transcriptome, most of our inferences revolve around changes in average expression. However, more recent examples have demonstrated that analysis of the variability of gene...
Genomics and metagenomics have become ubiquitous research efforts. Here we will show details of the development of physical, computational, and even space-based standards for metagenomi...
A recent clinical trial of the AR inhibitor enzalutamide in patients with TNBC included an exploratory endpoint using RNA sequencing to identify a genomic signature of patients likely to resp...
Biobanks are a powerful resource in the advancement of precision medicine, and integrating large scale genomics data across Biobank cohorts offer opportunities to further enhance and expedite...
Recent advances in DNA sequencing have now made it possible to characterize genomes, transcriptomes and even methylomes which is transforming both basic research and clinical practice. Whole...
DATE: December 14, 2016TIME: 9:00 AM PT, 12:00 PM ETMicroarrays and nucleotide sequencers have become commonplace tools in current research, yet until now, equivalent technologies for p...
DATE: January 30, 2018TIME: 9:00AM PST, 12:00PM ESTInfectious disease surveillance and monitoring is critical in settings where disease outbreaks and antibiotic resistance can dramatica...
DATE: November 15, 2017TIME: 09:00am PST, 12:00pm ESTMicroRNAs (miRNA) are a class of small non-coding RNAs (approximately 21 nt long) that bind complementary sequences in target mRNAs...
Currently, prostate cancer is the second leading cause of death from cancer in North America, the most frequent malignancy in men from all ethnicities, surpassing lung cancer. Prostate tumors...
DATE: October 17, 2017TIME: 08:00am PDT, 11:00am EDTResearching and understanding the mechanisms of drug resistance are essential to determine therapies that are more effective on an in...
Acral lentiginous melanoma (ALM) is a rare sun-shielded melanoma subtype associated with worse survival than cutaneous melanoma (CM), a more common form of skin cancer linked to exposure to u...
Nanopore sequencing has enormous potential for application to cancer, but specifically offers advantages into two main arenas, epigenetics and structural variation. Methylation is well-known...
DATE: September 6, 2017TIME: 9:00AM PST, 12:00PM ET The era of using extracellular vesicles (EVs) and exosomes for regenerative medicine applications in the clinic is here. We...
Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (iPSCs) as well as engineered heart muscles offer great potential for regenerative applications by CM transplantation, f...
Therapeutic application of pluripotent stem (PS) cell-derived products represents the ultimate goal of stem cell research. In order to apply this technology to patients, it is fundamental to ...
In the last years, progress has been made regarding the differentiation of human pluripotent stem cells into neural stem cells and astrocytes, growing into neurospheres and cerebral organoids...
As reprogramming methodologies have become more reliable and efficient, corresponding improvements were needed in the characterization workflow as well; specifically in terms of the speed, ef...
Disease-specific human pluripotent stem cells (hPSCs) represent a new chance to unravel cellular and molecular mechanisms of neurological diseases. Along this line, we were among the first to...
DATE: June 28, 2017TIME: 9:00AM PDT, 12:00PM EDT, 6:00PM CESTMany RNA binding proteins (RBPs) regulate the selection of alternative polyA sites. To understand their regulatory principle...
DATE: June 27, 2017TIME: 8:00am PT, 11:00am ETThe purpose of this study is to identify genetic variants that influence cellular responses, and patterns of M.tb infection and growth in h...
Unfortunately due to technical issues this webinar has been delayed until June 26th. If you are unable to make the new time, it will be available on demand for you to view.DATE: June 26,...
DATE: June 8, 2017TIME: 10:00AM PDT, 1:00PM EDT, 7:00PM CESTAlzheimer’s Disease (AD) is the result of complex interactions between risk factors that cause pleiotropic changes in m...
In this seminar, I will discuss issues in transcriptome analysis. I will first talk about core aspects - how we analyze the activity patterns of genes in model organisms and humans. I will fo...
When studying the transcriptome, most of our inferences revolve around changes in average expression. However, more recent examples have demonstrated that analysis of the variability of gene...
Genomics and metagenomics have become ubiquitous research efforts. Here we will show details of the development of physical, computational, and even space-based standards for metagenomi...
A recent clinical trial of the AR inhibitor enzalutamide in patients with TNBC included an exploratory endpoint using RNA sequencing to identify a genomic signature of patients likely to resp...
Biobanks are a powerful resource in the advancement of precision medicine, and integrating large scale genomics data across Biobank cohorts offer opportunities to further enhance and expedite...
Recent advances in DNA sequencing have now made it possible to characterize genomes, transcriptomes and even methylomes which is transforming both basic research and clinical practice. Whole...
DATE: December 14, 2016TIME: 9:00 AM PT, 12:00 PM ETMicroarrays and nucleotide sequencers have become commonplace tools in current research, yet until now, equivalent technologies for p...