Congenital CMV is the most frequent infectious cause of neonatal malformation in developed nations. It is more prevalent than other neonatal conditions such as spina bifida and Down syndrome...
Viruses are the causative agents of approximately 12% of human cancers. The most recently discovered herpesvirus, Kaposi’s sarcoma herpesvirus (KSHV) is known to cause three human canc...
Sepsis is a life-threatening condition that is caused by the immune system’s inability to respond appropriately to an infection. How sepsis can change the gut microbiome in ways that a...
The host response to infection is a critical determinant of virus pathogenicity. Emerging viruses require the host cellular machinery to replicate and successfully infect new hosts, and must...
Asthma is an increasing health concern affecting more than 25 million individuals in the United States and more than 300 million individuals worldwide. In some cases, sensitization or exposu...
The statement by Dimitri Ivanovsky in 1882 that "the sap of leaves infected with tobacco mosaic disease retains its infectious properties even after filtration through Chamberland filte...
To establish productive infection, plant viruses need to be able to efficiently invade and spread within a plant. Most viruses are introduced into a plant via the epidermal or mesophyll cell...
The regions of our genome responsible for encoding the genes that regulate our immune response are some of the most complex and polymorphic known. This complexity encompasses multiple types...
Human chromosome 19q13.4 contains genes encoding killer-cell immunoglobulin-like receptors (KIR). The region has certain properties such as single nucleotide variation, structural variation,...
The receptor binding domain (RBD) of the SARS-CoV-2 spike glycoprotein mediates viral attachment to ACE2 receptor, and is a major determinant of host range and a dominant target of neutraliz...
Background: Haemophilus influenzae is the causative agent of multiple human disease conditions among multiple sites in the human body. Underlying genetic mechanisms are elusive, particularly...
While viral fusion proteins are highly desirable for subunit vaccine generation, their inherent metastable nature complicates implementation and development. We have harnessed the structural...
The recent outbreak of SARS-CoV-2 underscores the need for understanding the evolutionary processes that drive the emergence and adaptation of zoonotic viruses in humans. Here, we show that...
While the frequency of pandemic threats seems to be increasing, we fortunately have new tools and technologies to make vaccines with more precision and speed and that support a more proactiv...
Seasonal and pandemic influenza virus infections can cause significant disease worldwide. Current vaccines only provide limited, short-lived protection, and antigenic drift/shift in the hema...
DATE: August 27, 2020 TIME: 7:00am PT Novel anti-viral medications, including biologics and small molecule inhibitors, as well as serologic diagnostic tool sets are in urgent demand to fight...
SARS-CoV-2 has created significant challenges for laboratories, requiring the development, validation, and scale up of testing in a very short time period--often this was done for multiple m...
DATA: 19 de agosto, 2020 Horário: às 15:00 horas Desde que foi detectado pela primeira vez em Wuhan, China, em 2019, o novo coronavírus SARS-CoV-2 e a doença que...
FECHA: 19 de Agosto, 2020 HORA: 10:00 AM PST 1:00 PM CST Desde que se detectó por primera vez en Wuhan, China, en 2019, el nuevo coronavirus SARS-CoV-2 y la enfermedad que causa, COVI...
DATE: August 18, 2020 TIME: 6:00am PDT, 9:00pm EDT Hundreds of HPV tests with different variants are commercially available globally, but many of these tests do not meet the performance char...
DATE: August 11, 2020 TIME: 10:00am PDT, 1:00pm EDT Biopharma researchers facing a difficult time adopting CE-SDS for purity/heterogeneity analysis of new protein modalities can now...
This talk will touch on several key points: PhD (MD) important grounding in science; how to develop friendships, gather mentors and collaborators; keep up with the literature; look at eviden...
In this presentation Shameema Sikder will discuss her career trajectory starting as an undergraduate studying chemical engineering and biochemistry to an Associate Professor of Ophthalmology...
In this presentation, I will discuss my experiences leading to my current position as a scientist and team leader, focused on chemical biology and drug discovery in the pharmaceutical indust...
Congenital CMV is the most frequent infectious cause of neonatal malformation in developed nations. It is more prevalent than other neonatal conditions such as spina bifida and Down syndrome...
Viruses are the causative agents of approximately 12% of human cancers. The most recently discovered herpesvirus, Kaposi’s sarcoma herpesvirus (KSHV) is known to cause three human canc...
Sepsis is a life-threatening condition that is caused by the immune system’s inability to respond appropriately to an infection. How sepsis can change the gut microbiome in ways that a...
The host response to infection is a critical determinant of virus pathogenicity. Emerging viruses require the host cellular machinery to replicate and successfully infect new hosts, and must...
Asthma is an increasing health concern affecting more than 25 million individuals in the United States and more than 300 million individuals worldwide. In some cases, sensitization or exposu...
The statement by Dimitri Ivanovsky in 1882 that "the sap of leaves infected with tobacco mosaic disease retains its infectious properties even after filtration through Chamberland filte...
To establish productive infection, plant viruses need to be able to efficiently invade and spread within a plant. Most viruses are introduced into a plant via the epidermal or mesophyll cell...
The regions of our genome responsible for encoding the genes that regulate our immune response are some of the most complex and polymorphic known. This complexity encompasses multiple types...
Human chromosome 19q13.4 contains genes encoding killer-cell immunoglobulin-like receptors (KIR). The region has certain properties such as single nucleotide variation, structural variation,...
The receptor binding domain (RBD) of the SARS-CoV-2 spike glycoprotein mediates viral attachment to ACE2 receptor, and is a major determinant of host range and a dominant target of neutraliz...
Background: Haemophilus influenzae is the causative agent of multiple human disease conditions among multiple sites in the human body. Underlying genetic mechanisms are elusive, particularly...
While viral fusion proteins are highly desirable for subunit vaccine generation, their inherent metastable nature complicates implementation and development. We have harnessed the structural...
The recent outbreak of SARS-CoV-2 underscores the need for understanding the evolutionary processes that drive the emergence and adaptation of zoonotic viruses in humans. Here, we show that...
While the frequency of pandemic threats seems to be increasing, we fortunately have new tools and technologies to make vaccines with more precision and speed and that support a more proactiv...
Seasonal and pandemic influenza virus infections can cause significant disease worldwide. Current vaccines only provide limited, short-lived protection, and antigenic drift/shift in the hema...
DATE: August 27, 2020 TIME: 7:00am PT Novel anti-viral medications, including biologics and small molecule inhibitors, as well as serologic diagnostic tool sets are in urgent demand to fight...
SARS-CoV-2 has created significant challenges for laboratories, requiring the development, validation, and scale up of testing in a very short time period--often this was done for multiple m...
DATA: 19 de agosto, 2020 Horário: às 15:00 horas Desde que foi detectado pela primeira vez em Wuhan, China, em 2019, o novo coronavírus SARS-CoV-2 e a doença que...
FECHA: 19 de Agosto, 2020 HORA: 10:00 AM PST 1:00 PM CST Desde que se detectó por primera vez en Wuhan, China, en 2019, el nuevo coronavirus SARS-CoV-2 y la enfermedad que causa, COVI...
DATE: August 18, 2020 TIME: 6:00am PDT, 9:00pm EDT Hundreds of HPV tests with different variants are commercially available globally, but many of these tests do not meet the performance char...
DATE: August 11, 2020 TIME: 10:00am PDT, 1:00pm EDT Biopharma researchers facing a difficult time adopting CE-SDS for purity/heterogeneity analysis of new protein modalities can now...
This talk will touch on several key points: PhD (MD) important grounding in science; how to develop friendships, gather mentors and collaborators; keep up with the literature; look at eviden...
In this presentation Shameema Sikder will discuss her career trajectory starting as an undergraduate studying chemical engineering and biochemistry to an Associate Professor of Ophthalmology...
In this presentation, I will discuss my experiences leading to my current position as a scientist and team leader, focused on chemical biology and drug discovery in the pharmaceutical indust...
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