Animal Models a living organisms in which normative biology or behavior can be studied, or in which a spontaneous or induced pathological process can be investigated, and in which the phenomenon in one or more respects resembles the same phenomenon in humans or other species of animal.
In the last decade the number of publications in zebrafish tripled, from 938 in 2005 to 2432 in 2015 (Pubmed database; keyword: “zebrafish” in Title/Abstract;...
Understanding systematic biases in primary research are important for appropriate interpretation of research and recognizing features of reproducible research. Systematic biases arise from th...
Animal models have provided an important tool to help make the decision to take potential therapies from preclinical studies to humans. In the past several years, the strong reliance of the p...
Surgerized animals play a crucial role in preclinical research aimed at drug and medical device discovery into treatments for humans. When implementing new in-house surgical models to perform...
Animal studies still play a crucial role in research aimed at improving human health care. When performing animal studies, the results and their interpretation are not always straightforward....
This presentation will discuss variables in rodent colony management that can affect colony breeding efficiency, rodent health, and factors that can modulate rodent models of disease. V...
The use of laboratory animals requires education and training of persons who are to design and/or perform animal experiments. It is essential for these persons to practice various procedures...
Reproducibility refers to the ability of an experiment or study to be replicated, either by the same person or group or by others working independently. With regard to scientific public...
Is your facility providing relevant nesting material or are you just checking off a box? This presentation will discuss the importance of nesting for rodents, their behaviors, and today...
Animal studies performed on behalf of GlaxoSmithKline (GSK) are expected to uphold the core principles established by Corporate Policy 403, ‘Care, Welfare and Treatment of Animals by GS...
Translational failure in biomedicine has led to much soul-searching about the causes for this. Amongst many others (misunderstanding of statistical tests, vibration of effects, flexibility in...
Noise and vibration are very effective activators of stress pathways in rodent models that can increase variability in animal models, thereby confounding virtually every area of biomedical an...
Why did we change focus from the 3Rs to Systematic Reviews? Questionnaires on the 3Rs have revealed that the 3R search gets no high priority and the 3R search process is never included in fun...
Quality animal research is based on quality animal care and use. This is achieved by coordinating several key personnel and activities, and implementing appropriate animal care and use proced...
December 8th, 2015 8:00 am PT, 10:00 am CT
Cryopreservation of post-mitotic, induced pluripotent stem cell-derived midbrain lineage dopamine neurons (iPSC-mDA) is a significant advan...
Date: October 27th, 2015
TIME: 8am PDT, 11am EDT, 3pm GMT, 11pm Beijing
In recent years there have been great advances in automated microscopy and imaging for generating more predictive, ...
The 95% failure rate of anticancer therapeutic being approved after positive Phase III trials suggests that existing pre-clinical approaches and tools are inadequate predictors of clinical ou...
Date: Wednesday, June 24th, 2015 Time: 09:00AM PDT, 12:00PM EDT, 4:00PM GMT Solarisâ„¢ is a new open-air fluorescence imaging system developed by PerkinElmer, enabling translational in vivo pre...
Date: June 16, 2015Time: 8:00AM Pacific time, 11:00AM Eastern TimeGroup 2 innate lymphoid cells (ILC2s) are recently described innate immune cells that contribute to type 2 inflammation, tiss...
Date: Thursday, June 11th, 2015Time: 07:00AM PDT, 10:00AM EDT, 03:00PM BST Alzheimer's disease (AD) is the most common form of dementia with nearly 44 million people affected worldwide. Chara...
Asthma is heritable, influenced by the environment, and is modified by in utero exposures and aging; all of these features are also common to epigenetic regulation. Furthermore, genetic varia...
Impulsivity can be defined as the tendency to act prematurely without foresight. Behavioural and neurobiological analysis of this construct, based on evidence from both animal and human studi...
The hippocampal formation is one of the most extensively studied regions of the brain, with well described anatomy and basic physiology; moreover, aspects of human memory mediated by hippocam...
The dopamine-containing neurons of the midbrain have been implicated in a broad array of psychiatric disorders, ranging from schizophrenia to drug abuse and depression. However, studies seem...
In the last decade the number of publications in zebrafish tripled, from 938 in 2005 to 2432 in 2015 (Pubmed database; keyword: “zebrafish” in Title/Abstract;...
Understanding systematic biases in primary research are important for appropriate interpretation of research and recognizing features of reproducible research. Systematic biases arise from th...
Animal models have provided an important tool to help make the decision to take potential therapies from preclinical studies to humans. In the past several years, the strong reliance of the p...
Surgerized animals play a crucial role in preclinical research aimed at drug and medical device discovery into treatments for humans. When implementing new in-house surgical models to perform...
Animal studies still play a crucial role in research aimed at improving human health care. When performing animal studies, the results and their interpretation are not always straightforward....
This presentation will discuss variables in rodent colony management that can affect colony breeding efficiency, rodent health, and factors that can modulate rodent models of disease. V...
The use of laboratory animals requires education and training of persons who are to design and/or perform animal experiments. It is essential for these persons to practice various procedures...
Reproducibility refers to the ability of an experiment or study to be replicated, either by the same person or group or by others working independently. With regard to scientific public...
Is your facility providing relevant nesting material or are you just checking off a box? This presentation will discuss the importance of nesting for rodents, their behaviors, and today...
Animal studies performed on behalf of GlaxoSmithKline (GSK) are expected to uphold the core principles established by Corporate Policy 403, ‘Care, Welfare and Treatment of Animals by GS...
Translational failure in biomedicine has led to much soul-searching about the causes for this. Amongst many others (misunderstanding of statistical tests, vibration of effects, flexibility in...
Noise and vibration are very effective activators of stress pathways in rodent models that can increase variability in animal models, thereby confounding virtually every area of biomedical an...
Why did we change focus from the 3Rs to Systematic Reviews? Questionnaires on the 3Rs have revealed that the 3R search gets no high priority and the 3R search process is never included in fun...
Quality animal research is based on quality animal care and use. This is achieved by coordinating several key personnel and activities, and implementing appropriate animal care and use proced...
December 8th, 2015 8:00 am PT, 10:00 am CT
Cryopreservation of post-mitotic, induced pluripotent stem cell-derived midbrain lineage dopamine neurons (iPSC-mDA) is a significant advan...
Date: October 27th, 2015
TIME: 8am PDT, 11am EDT, 3pm GMT, 11pm Beijing
In recent years there have been great advances in automated microscopy and imaging for generating more predictive, ...
The 95% failure rate of anticancer therapeutic being approved after positive Phase III trials suggests that existing pre-clinical approaches and tools are inadequate predictors of clinical ou...
Date: Wednesday, June 24th, 2015 Time: 09:00AM PDT, 12:00PM EDT, 4:00PM GMT Solarisâ„¢ is a new open-air fluorescence imaging system developed by PerkinElmer, enabling translational in vivo pre...
Date: June 16, 2015Time: 8:00AM Pacific time, 11:00AM Eastern TimeGroup 2 innate lymphoid cells (ILC2s) are recently described innate immune cells that contribute to type 2 inflammation, tiss...
Date: Thursday, June 11th, 2015Time: 07:00AM PDT, 10:00AM EDT, 03:00PM BST Alzheimer's disease (AD) is the most common form of dementia with nearly 44 million people affected worldwide. Chara...
Asthma is heritable, influenced by the environment, and is modified by in utero exposures and aging; all of these features are also common to epigenetic regulation. Furthermore, genetic varia...
Impulsivity can be defined as the tendency to act prematurely without foresight. Behavioural and neurobiological analysis of this construct, based on evidence from both animal and human studi...
The hippocampal formation is one of the most extensively studied regions of the brain, with well described anatomy and basic physiology; moreover, aspects of human memory mediated by hippocam...
The dopamine-containing neurons of the midbrain have been implicated in a broad array of psychiatric disorders, ranging from schizophrenia to drug abuse and depression. However, studies seem...
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