Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
Research on human brain development and neurological diseases is limited by the lack of advanced experimental in vitro models that truly recapitulate the complexity of the human brain. Here, ...
The identity of somatic and pluripotent cells can be epigenetically reprogrammed and forced to adapt a new functional cell state by different methods and distinct combinations of exogenous fa...
Regenerative medicine therapeutics aimed at restoring normal cell function due to trauma and disease are gaining increasing momentum in clinical trials. For this purpose, lentivirus-based gen...
Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (iPSCs) as well as engineered heart muscles offer great potential for regenerative applications by CM transplantation, f...
Pluripotent stem cell (PSC) culture at commercial scale requires a shift from the current manual processing methods and costly materials to deliver affordable differentiated cell products in...
The continuous generation of blood cells throughout life relies on the existence of hematopoietic stem cells (HSC) generated during embryogenesis. Given the importance of HSC transplantation...
There are a number of free and independent scholarly publishing tools available that save journal authors time and ensure research is found, read and tracked. In this talk, we will explore th...
The human inner ear contains ~75,000 sensory hair cells that detect sound or movement via mechanosensitive hair bundles and transmit signals to the brain via specialized sensory neurons. Inne...
Therapeutic application of pluripotent stem (PS) cell-derived products represents the ultimate goal of stem cell research. In order to apply this technology to patients, it is fundamental to ...
The availability of well-characterised monoclonal antibodies (mAbs) detecting cell-surface epitopes on human pluripotent stem cells (hPSCs) provides useful research tools to investigate the c...
Human pluripotent stem cells (hPSCs) and their derivatives are increasingly being used in industry to gain a competitive edge in drug discovery and a new wave of biotechnology start-up compan...
For optimal use of human induced pluripotent stem cells (hiPSCs) it is essential to identify lines that are fully reprogrammed and of high quality with proven pluripotency in terms of differe...
Since 1993, Gibco™ B-27™ Supplement and Neurobasal™ Medium has been the trusted standard for a variety of neuronal culture applications, with citations in more than 11,000 p...
CRISPR-Cas9 systems provide a platform for high efficiency genome editing that are enabling innovative applications of mammalian cell engineering. The delivery of Cas9 plasmid DNA or mR...
As reprogramming methodologies have become more reliable and efficient, corresponding improvements were needed in the characterization workflow as well; specifically in terms of the speed, ef...
The development of the CRISPR/Cas9 gene-editing platform enables the rapid generation of new genetically modified stem cell models of human diseases, as well as providing new potential therap...
For many decades, cell lines have been cultured in standard CO2 incubators at “normal” atmospheric oxygen concentrations of about 21%. But oxygen concentrations in the human or an...
Disease-specific human pluripotent stem cells (hPSCs) represent a new chance to unravel cellular and molecular mechanisms of neurological diseases. Along this line, we were among the first to...
DATE: June 28, 2017TIME: 10:30am PT, 1:30pm ETThis webinar will describe the implementation of the Oncomine Lung cfDNA Assay from Thermo Fisher Scientific in the Advanced Molecular...
DATE: June 28, 2017TIME: 7:00am PT, 10am ETAs gene therapy approaches usually require large amounts of AAV vectors for clinical use, few manufacturing processes have been repo...
不好意思，由于遇到技术困难，此网上讨论会延迟到六月二十八日。若此时间对您不方便，您将可事后从网站上电阅。DATE: June 28, 2017 TIME: 9:00 AM HKTORDATE: June 27, 2017TIME: 6:00 PM PDT 深入了解使用一个功能性密闭状态的自动化细胞培养流...
DATE: June 21, 2017TIME: 7:30am PT, 10:30am ET, 4:30pm CETChoosing the right path to discovery can hasten your success, but the wrong path can lead to missteps that extend the journey a...
EVENT DETAILS: DATE: June 13, 2017TIME: 9:00am PT, 12:00pm ETThermo Fisher Scientific is proud to present the SyncD3 webinar series. As a thought-leader in...
The emergence of technology for development of induced pluripotent stem cells (iPSCs) from somatic cells, such as skin and blood cells, has resulted in the ability of researchers to have limi...
Research on human brain development and neurological diseases is limited by the lack of advanced experimental in vitro models that truly recapitulate the complexity of the human brain. Here, ...
The identity of somatic and pluripotent cells can be epigenetically reprogrammed and forced to adapt a new functional cell state by different methods and distinct combinations of exogenous fa...
Regenerative medicine therapeutics aimed at restoring normal cell function due to trauma and disease are gaining increasing momentum in clinical trials. For this purpose, lentivirus-based gen...
Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (iPSCs) as well as engineered heart muscles offer great potential for regenerative applications by CM transplantation, f...
Pluripotent stem cell (PSC) culture at commercial scale requires a shift from the current manual processing methods and costly materials to deliver affordable differentiated cell products in...
The continuous generation of blood cells throughout life relies on the existence of hematopoietic stem cells (HSC) generated during embryogenesis. Given the importance of HSC transplantation...
There are a number of free and independent scholarly publishing tools available that save journal authors time and ensure research is found, read and tracked. In this talk, we will explore th...
The human inner ear contains ~75,000 sensory hair cells that detect sound or movement via mechanosensitive hair bundles and transmit signals to the brain via specialized sensory neurons. Inne...
Therapeutic application of pluripotent stem (PS) cell-derived products represents the ultimate goal of stem cell research. In order to apply this technology to patients, it is fundamental to ...
The availability of well-characterised monoclonal antibodies (mAbs) detecting cell-surface epitopes on human pluripotent stem cells (hPSCs) provides useful research tools to investigate the c...
Human pluripotent stem cells (hPSCs) and their derivatives are increasingly being used in industry to gain a competitive edge in drug discovery and a new wave of biotechnology start-up compan...
For optimal use of human induced pluripotent stem cells (hiPSCs) it is essential to identify lines that are fully reprogrammed and of high quality with proven pluripotency in terms of differe...
Since 1993, Gibco™ B-27™ Supplement and Neurobasal™ Medium has been the trusted standard for a variety of neuronal culture applications, with citations in more than 11,000 p...
CRISPR-Cas9 systems provide a platform for high efficiency genome editing that are enabling innovative applications of mammalian cell engineering. The delivery of Cas9 plasmid DNA or mR...
As reprogramming methodologies have become more reliable and efficient, corresponding improvements were needed in the characterization workflow as well; specifically in terms of the speed, ef...
The development of the CRISPR/Cas9 gene-editing platform enables the rapid generation of new genetically modified stem cell models of human diseases, as well as providing new potential therap...
For many decades, cell lines have been cultured in standard CO2 incubators at “normal” atmospheric oxygen concentrations of about 21%. But oxygen concentrations in the human or an...
Disease-specific human pluripotent stem cells (hPSCs) represent a new chance to unravel cellular and molecular mechanisms of neurological diseases. Along this line, we were among the first to...
DATE: June 28, 2017TIME: 10:30am PT, 1:30pm ETThis webinar will describe the implementation of the Oncomine Lung cfDNA Assay from Thermo Fisher Scientific in the Advanced Molecular...
DATE: June 28, 2017TIME: 7:00am PT, 10am ETAs gene therapy approaches usually require large amounts of AAV vectors for clinical use, few manufacturing processes have been repo...
不好意思，由于遇到技术困难，此网上讨论会延迟到六月二十八日。若此时间对您不方便，您将可事后从网站上电阅。DATE: June 28, 2017 TIME: 9:00 AM HKTORDATE: June 27, 2017TIME: 6:00 PM PDT 深入了解使用一个功能性密闭状态的自动化细胞培养流...
DATE: June 21, 2017TIME: 7:30am PT, 10:30am ET, 4:30pm CETChoosing the right path to discovery can hasten your success, but the wrong path can lead to missteps that extend the journey a...
EVENT DETAILS: DATE: June 13, 2017TIME: 9:00am PT, 12:00pm ETThermo Fisher Scientific is proud to present the SyncD3 webinar series. As a thought-leader in...
The emergence of technology for development of induced pluripotent stem cells (iPSCs) from somatic cells, such as skin and blood cells, has resulted in the ability of researchers to have limi...
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