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    Cell Line Development

    Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.

    Webinars

    • SEP 14, 2017 | 10:30 AM
      Clinical and Laboratory Studies of Zika Virus Infection
      Clinical and Laboratory Studies of Zika Virus Infection
      An unbiased metagenomic next-generation approach (mNGS) been shown to be useful in the broad identification of pathogens in clinical samples for infectious disease diagnosis, including viruse...
      Speaker: Charles Chiu, MD, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2017
      2
      SEP 13, 2017 | 1:30 PM
      The escalating challenges of antimicrobial resistance and the efforts to conquer these threats
      The escalating challenges of antimicrobial resistance and the...
      The global threat of antimicrobial resistance has been recognized by the World Health Organization, the United Nations and many other expert bodies. The burden of resistant pathogens is immen...
      Speaker: Glenn Tillotson, PhD, FIDSA, FCCP
      Presented at: Microbiology & Immunology Virtual Event Series 2017
      3 1
      SEP 13, 2017 | 9:00 AM
      Insights into virus replication: the role of co-opted host proteins and lipids
      Insights into virus replication: the role of co-opted host proteins...
      Virus – host interactions are currently among the most intensively studied research areas due to the promising new antiviral approaches emerging from these studies. Indeed, RNA viruses,...
      Speaker: Peter L. Nagy, MD., PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2017
      3
      SEP 12, 2017 | 8:00 AM
      Addressing the antibody reproducibility crisis: A panel  discussion with key scientific leaders
      Addressing the antibody reproducibility crisis: A panel discussion...
      DATE: September 12, 2017TIME: 8:00am PT, 11:00am ETEvery year, millions of dollars are wasted on poorly characterized and performing antibodies.  Key researchers in the antibody co...
      Speaker: Aled Edwards, PhD , Matt Baker , Anita Bandrowski, PhD , Paul Wallace, PhD , John Rogers, PhD , Christoph Hergersberg, PhD
      Presented at: Protein and Cell Analysis Education Series
      Sponsored By: Thermo Fisher Scientific
      5 1
      SEP 12, 2017 | 6:00 PM
      WEBINAR: A Case Study Review on Large-scale Manufacturing of Stem Cell Therapies
      WEBINAR: A Case Study Review on Large-scale Manufacturing of Stem...
      DATE: September 13, 2017 TIME:  9:00AM SGT 12:00PM AEDTORDATE: September 12, 2017TIME: 6:00PM PDT To transform the promises of cell-based therapies int...
      Speaker: Amel Tounsi, PhD
      Sponsored By: TERUMO BCT
      5 2
      SEP 06, 2017 | 9:00 AM
      WEBINAR: Manufacturing and characterization of therapeutic exosomes for clinical studies
      WEBINAR: Manufacturing and characterization of therapeutic exosomes...
      DATE: September 6, 2017TIME: 9:00AM PST, 12:00PM ET The era of using extracellular vesicles (EVs) and exosomes for regenerative medicine applications in the clinic is here. We...
      Speaker: Travis Antes, PhD
      Sponsored By: Miltenyi Biotec
      9
      SEP 01, 2017 | 12:00 AM
      A gut feeling about stem cell therapy for enteric neuropathies
      A gut feeling about stem cell therapy for enteric neuropathies
      The enteric nervous system (ENS) plays an essential role in gut motility. Diseases of the ENS result in bowel motility disorders that are some of the most challenging clinical conditions to m...
      Speaker: Lincon Stamp
      Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
      1
      AUG 29, 2017 | 9:00 AM
      Automated Optimization of IgG Production in CHO Cells
      Automated Optimization of IgG Production in CHO Cells
      DATE: August 29th, 2017TIME:  9:00am PT, 12:00pm ET Antibodies are frequently produced from a cell line that has been screened to ensure the protein is expressed with th...
      Speaker: Mike Kowalski, Ph.D. , David Apiyo
      Sponsored By: Biologics by Danaher, Biologics by Danaher
      4
      AUG 22, 2017 | 5:00 PM
      ケーススタディ: 治療用細胞製造のスケールアップ
      ケーススタディ: 治療用細胞製造のスケールアップ
      DATE: August 23, 2017TIME: 9:00AM JSTORDATE: August 22, 2017TIME: 5:00PM PDT, 6:00PM MDT 機能的閉鎖式の自動細胞培養プロセスを使用した T 細胞増殖、ウイルスベクター製造、および間葉系幹細胞(MSC)のスケールアップ製造について、詳しくご説明し...
      Speaker: Jim Beltzer, MS, PhD
      Sponsored By: TERUMO BCT
      5
      AUG 17, 2017 | 10:00 AM
      Applications of Counterflow Centrifugal Elutriation (CCE): Revival of an Old Tool
      Applications of Counterflow Centrifugal Elutriation (CCE): Revival...
      DATE: August 17, 2017TIME: 10:00am PT, 1:00pm ETCounterflow centrifugal elutriation (CCE) is a well-known technique used commonly several decades ago in scientific research. In this tec...
      Speaker: Anisha Rathi
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences
      4
      AUG 01, 2017 | 6:00 PM
      사례연구: 세포 치료제 제조 확장하기
      사례연구: 세포 치료제 제조 확장하기
      DATE: August 2, 2017TIME: 10:00AM HKTORDATE: August 1, 2017TIME: 6:00PM PT, 7:00PM MT 폐쇄된 자동 세포 배양 프로세스의 사용을 통한 T-세포 확장, 바이러스 벡터 생산 및 중간엽줄기세포(MSC)의 확장 생산에 대한 식견 갖기....
      Speaker: Jim Beltzer, MS, PhD
      Sponsored By: TERUMO BCT
      4
      AUG 01, 2017 | 12:00 AM
      Accelerating cures for rare childhood diseases using iPSC models
      Accelerating cures for rare childhood diseases using iPSC models
      Creating inducible Pluripotent Stem Cell (iPSC) collections of rare patients scattered world-wide can lower the barrier of biological discovery of rare disease, provide a platform for potenti...
      Speaker: Christina Waters
      Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
      1
      JUL 25, 2017 | 9:00 AM
      WEBINAR: Functional Genomics and Drug Metabolism
      WEBINAR: Functional Genomics and Drug Metabolism
      EVENT DETAILS:DATE: July 25, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science...
      Speaker: David Piper, PhD
      Sponsored By: Thermo Fisher Scientific
      7 1
      JUL 20, 2017 | 10:00 AM
      WEBINAR: Innovative quantitative imaging techniques and their utility in advancing neurobiology research
      WEBINAR: Innovative quantitative imaging techniques and their...
      DATE: July 20, 2017TIME: 10:00am PT, 1:00pm ETPart 1 - Daniel Beacham: Case study showing how CyQUANT Direct Cell Proliferation and Fluo-4 calcium imaging assays were us...
      Speaker: Dan Beacham, Ph.D. , Nicholas Radio Ph.D. , Michael Derr, M.S.
      Sponsored By: Thermo Fisher Scientific/Gibco
      3
      JUL 01, 2017 | 8:00 AM
      Patient-specific hiPSCs for understanding diabetes disease mechanisms
      Patient-specific hiPSCs for understanding diabetes disease mechanisms
      Diabetes is a debilitating chronic disease that is spirally out of control. Fundamentally, the progressive failure of pancreatic beta cells results in decreased insulin secretion, ultimately ...
      Speaker: Adrian Teo
      Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
      3
      JUL 01, 2017 | 8:00 AM
      Genomic profiling reveals novel PAX7 targets CD54, integrin α9β1 and SDC2, as markers for isolation of human ES/iPS cell-derived muscle progenitors
      Genomic profiling reveals novel PAX7 targets CD54, integrin α9β1...
      Therapeutic application of pluripotent stem (PS) cell-derived products represents the ultimate goal of stem cell research. In order to apply this technology to patients, it is fundamental to ...
      Speaker: Alessandro Magli
      Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
      1
      JUL 01, 2017 | 8:00 AM
      Building inner ear organoids from human pluripotent stem cells through directed self-assembly
      Building inner ear organoids from human pluripotent stem cells...
      The human inner ear contains ~75,000 sensory hair cells that detect sound or movement via mechanosensitive hair bundles and transmit signals to the brain via specialized sensory neurons. Inne...
      Speaker: Karl Koehler
      Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
      1
      JUL 01, 2017 | 8:00 AM
      Directed differentiation of hematopoietic cells from human pluripotent stem cells
      Directed differentiation of hematopoietic cells from human pluripotent...
      The continuous generation of blood cells throughout life relies on the existence of hematopoietic stem cells (HSC) generated during embryogenesis. Given the importance of HSC transplantation...
      Speaker: Alessandra Giorgetti
      Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
      3
      JUL 01, 2017 | 8:00 AM
      Pluripotent stem cell bioprocessing platforms for cell therapy manufacturing
      Pluripotent stem cell bioprocessing platforms for cell therapy...
      Pluripotent stem cell (PSC) culture at commercial scale requires a shift from the current manual processing methods and costly materials to deliver affordable differentiated cell products in...
      Speaker: Jahid Hasan
      Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
      2
      JUL 01, 2017 | 8:00 AM
      Custom-tailored cardiomyocytes: Directed differentiation of human pluripotent stem cells into defined atrial and ventricular cardiomyocyte subtypes
      Custom-tailored cardiomyocytes: Directed differentiation of human...
      Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (iPSCs) as well as engineered heart muscles offer great potential for regenerative applications by CM transplantation, f...
      Speaker: Lukas Cyganek
      Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
      2
      JUL 01, 2017 | 8:00 AM
      Identification of a High Titer Lentiviral Production Alternative to Facilitate Regenerative Medicine Therapies
      Identification of a High Titer Lentiviral Production Alternative...
      Regenerative medicine therapeutics aimed at restoring normal cell function due to trauma and disease are gaining increasing momentum in clinical trials. For this purpose, lentivirus-based gen...
      Speaker: Calley Hirsch, PhD
      Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
      2
      JUL 01, 2017 | 8:00 AM
      Mechanisms for Assembling and Resolving Naïve Pluripotency
      Mechanisms for Assembling and Resolving Naïve Pluripotency
      The identity of somatic and pluripotent cells can be epigenetically reprogrammed and forced to adapt a new functional cell state by different methods and distinct combinations of exogenous fa...
      Speaker: Jacob Hanna
      Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
      4
      JUL 01, 2017 | 8:00 AM
      Industry uses of human pluripotent stem cells
      Industry uses of human pluripotent stem cells
      Human pluripotent stem cells (hPSCs) and their derivatives are increasingly being used in industry to gain a competitive edge in drug discovery and a new wave of biotechnology start-up compan...
      Speaker: Stuart Chambers
      Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
      2
      JUL 01, 2017 | 8:00 AM
      Braingineering's human midbrain organoids as novel model for neurodegenerative diseases
      Braingineering's human midbrain organoids as novel model for neurodegenerative...
      Research on human brain development and neurological diseases is limited by the lack of advanced experimental in vitro models that truly recapitulate the complexity of the human brain. Here, ...
      Speaker: Jens Schwamborn
      Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
      2
    SEP 14, 2017 | 10:30 AM
    Clinical and Laboratory Studies of Zika Virus Infection
    Clinical and Laboratory Studies of Zika Virus Infection
    An unbiased metagenomic next-generation approach (mNGS) been shown to be useful in the broad identification of pathogens in clinical samples for infectious disease diagnosis, including viruse...
    Speaker: Charles Chiu, MD, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2017
    2
    SEP 13, 2017 | 1:30 PM
    The escalating challenges of antimicrobial resistance and the efforts to conquer these threats
    The escalating challenges of antimicrobial resistance and the...
    The global threat of antimicrobial resistance has been recognized by the World Health Organization, the United Nations and many other expert bodies. The burden of resistant pathogens is immen...
    Speaker: Glenn Tillotson, PhD, FIDSA, FCCP
    Presented at: Microbiology & Immunology Virtual Event Series 2017
    3 1
    SEP 13, 2017 | 9:00 AM
    Insights into virus replication: the role of co-opted host proteins and lipids
    Insights into virus replication: the role of co-opted host proteins...
    Virus – host interactions are currently among the most intensively studied research areas due to the promising new antiviral approaches emerging from these studies. Indeed, RNA viruses,...
    Speaker: Peter L. Nagy, MD., PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2017
    3
    SEP 12, 2017 | 8:00 AM
    Addressing the antibody reproducibility crisis: A panel  discussion with key scientific leaders
    Addressing the antibody reproducibility crisis: A panel discussion...
    DATE: September 12, 2017TIME: 8:00am PT, 11:00am ETEvery year, millions of dollars are wasted on poorly characterized and performing antibodies.  Key researchers in the antibody co...
    Speaker: Aled Edwards, PhD , Matt Baker , Anita Bandrowski, PhD , Paul Wallace, PhD , John Rogers, PhD , Christoph Hergersberg, PhD
    Presented at: Protein and Cell Analysis Education Series
    Sponsored By: Thermo Fisher Scientific
    5 1
    SEP 12, 2017 | 6:00 PM
    WEBINAR: A Case Study Review on Large-scale Manufacturing of Stem Cell Therapies
    WEBINAR: A Case Study Review on Large-scale Manufacturing of Stem...
    DATE: September 13, 2017 TIME:  9:00AM SGT 12:00PM AEDTORDATE: September 12, 2017TIME: 6:00PM PDT To transform the promises of cell-based therapies int...
    Speaker: Amel Tounsi, PhD
    Sponsored By: TERUMO BCT
    5 2
     
     
  • SEP 06, 2017 | 9:00 AM
    WEBINAR: Manufacturing and characterization of therapeutic exosomes for clinical studies
    WEBINAR: Manufacturing and characterization of therapeutic exosomes...
    DATE: September 6, 2017TIME: 9:00AM PST, 12:00PM ET The era of using extracellular vesicles (EVs) and exosomes for regenerative medicine applications in the clinic is here. We...
    Speaker: Travis Antes, PhD
    Sponsored By: Miltenyi Biotec
    9
    SEP 01, 2017 | 12:00 AM
    A gut feeling about stem cell therapy for enteric neuropathies
    A gut feeling about stem cell therapy for enteric neuropathies
    The enteric nervous system (ENS) plays an essential role in gut motility. Diseases of the ENS result in bowel motility disorders that are some of the most challenging clinical conditions to m...
    Speaker: Lincon Stamp
    Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
    1
    AUG 29, 2017 | 9:00 AM
    Automated Optimization of IgG Production in CHO Cells
    Automated Optimization of IgG Production in CHO Cells
    DATE: August 29th, 2017TIME:  9:00am PT, 12:00pm ET Antibodies are frequently produced from a cell line that has been screened to ensure the protein is expressed with th...
    Speaker: Mike Kowalski, Ph.D. , David Apiyo
    Sponsored By: Biologics by Danaher, Biologics by Danaher
    4
    AUG 22, 2017 | 5:00 PM
    ケーススタディ: 治療用細胞製造のスケールアップ
    ケーススタディ: 治療用細胞製造のスケールアップ
    DATE: August 23, 2017TIME: 9:00AM JSTORDATE: August 22, 2017TIME: 5:00PM PDT, 6:00PM MDT 機能的閉鎖式の自動細胞培養プロセスを使用した T 細胞増殖、ウイルスベクター製造、および間葉系幹細胞(MSC)のスケールアップ製造について、詳しくご説明し...
    Speaker: Jim Beltzer, MS, PhD
    Sponsored By: TERUMO BCT
    5
    AUG 17, 2017 | 10:00 AM
    Applications of Counterflow Centrifugal Elutriation (CCE): Revival of an Old Tool
    Applications of Counterflow Centrifugal Elutriation (CCE): Revival...
    DATE: August 17, 2017TIME: 10:00am PT, 1:00pm ETCounterflow centrifugal elutriation (CCE) is a well-known technique used commonly several decades ago in scientific research. In this tec...
    Speaker: Anisha Rathi
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences
    4
     
     
  • AUG 01, 2017 | 6:00 PM
    사례연구: 세포 치료제 제조 확장하기
    사례연구: 세포 치료제 제조 확장하기
    DATE: August 2, 2017TIME: 10:00AM HKTORDATE: August 1, 2017TIME: 6:00PM PT, 7:00PM MT 폐쇄된 자동 세포 배양 프로세스의 사용을 통한 T-세포 확장, 바이러스 벡터 생산 및 중간엽줄기세포(MSC)의 확장 생산에 대한 식견 갖기....
    Speaker: Jim Beltzer, MS, PhD
    Sponsored By: TERUMO BCT
    4
    AUG 01, 2017 | 12:00 AM
    Accelerating cures for rare childhood diseases using iPSC models
    Accelerating cures for rare childhood diseases using iPSC models
    Creating inducible Pluripotent Stem Cell (iPSC) collections of rare patients scattered world-wide can lower the barrier of biological discovery of rare disease, provide a platform for potenti...
    Speaker: Christina Waters
    Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
    1
    JUL 25, 2017 | 9:00 AM
    WEBINAR: Functional Genomics and Drug Metabolism
    WEBINAR: Functional Genomics and Drug Metabolism
    EVENT DETAILS:DATE: July 25, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science...
    Speaker: David Piper, PhD
    Sponsored By: Thermo Fisher Scientific
    7 1
    JUL 20, 2017 | 10:00 AM
    WEBINAR: Innovative quantitative imaging techniques and their utility in advancing neurobiology research
    WEBINAR: Innovative quantitative imaging techniques and their...
    DATE: July 20, 2017TIME: 10:00am PT, 1:00pm ETPart 1 - Daniel Beacham: Case study showing how CyQUANT Direct Cell Proliferation and Fluo-4 calcium imaging assays were us...
    Speaker: Dan Beacham, Ph.D. , Nicholas Radio Ph.D. , Michael Derr, M.S.
    Sponsored By: Thermo Fisher Scientific/Gibco
    3
    JUL 01, 2017 | 8:00 AM
    Patient-specific hiPSCs for understanding diabetes disease mechanisms
    Patient-specific hiPSCs for understanding diabetes disease mechanisms
    Diabetes is a debilitating chronic disease that is spirally out of control. Fundamentally, the progressive failure of pancreatic beta cells results in decreased insulin secretion, ultimately ...
    Speaker: Adrian Teo
    Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
    3
     
     
  • JUL 01, 2017 | 8:00 AM
    Genomic profiling reveals novel PAX7 targets CD54, integrin α9β1 and SDC2, as markers for isolation of human ES/iPS cell-derived muscle progenitors
    Genomic profiling reveals novel PAX7 targets CD54, integrin α9β1...
    Therapeutic application of pluripotent stem (PS) cell-derived products represents the ultimate goal of stem cell research. In order to apply this technology to patients, it is fundamental to ...
    Speaker: Alessandro Magli
    Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
    1
    JUL 01, 2017 | 8:00 AM
    Building inner ear organoids from human pluripotent stem cells through directed self-assembly
    Building inner ear organoids from human pluripotent stem cells...
    The human inner ear contains ~75,000 sensory hair cells that detect sound or movement via mechanosensitive hair bundles and transmit signals to the brain via specialized sensory neurons. Inne...
    Speaker: Karl Koehler
    Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
    1
    JUL 01, 2017 | 8:00 AM
    Directed differentiation of hematopoietic cells from human pluripotent stem cells
    Directed differentiation of hematopoietic cells from human pluripotent...
    The continuous generation of blood cells throughout life relies on the existence of hematopoietic stem cells (HSC) generated during embryogenesis. Given the importance of HSC transplantation...
    Speaker: Alessandra Giorgetti
    Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
    3
    JUL 01, 2017 | 8:00 AM
    Pluripotent stem cell bioprocessing platforms for cell therapy manufacturing
    Pluripotent stem cell bioprocessing platforms for cell therapy...
    Pluripotent stem cell (PSC) culture at commercial scale requires a shift from the current manual processing methods and costly materials to deliver affordable differentiated cell products in...
    Speaker: Jahid Hasan
    Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
    2
    JUL 01, 2017 | 8:00 AM
    Custom-tailored cardiomyocytes: Directed differentiation of human pluripotent stem cells into defined atrial and ventricular cardiomyocyte subtypes
    Custom-tailored cardiomyocytes: Directed differentiation of human...
    Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (iPSCs) as well as engineered heart muscles offer great potential for regenerative applications by CM transplantation, f...
    Speaker: Lukas Cyganek
    Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
    2
     
     
  • JUL 01, 2017 | 8:00 AM
    Identification of a High Titer Lentiviral Production Alternative to Facilitate Regenerative Medicine Therapies
    Identification of a High Titer Lentiviral Production Alternative...
    Regenerative medicine therapeutics aimed at restoring normal cell function due to trauma and disease are gaining increasing momentum in clinical trials. For this purpose, lentivirus-based gen...
    Speaker: Calley Hirsch, PhD
    Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
    2
    JUL 01, 2017 | 8:00 AM
    Mechanisms for Assembling and Resolving Naïve Pluripotency
    Mechanisms for Assembling and Resolving Naïve Pluripotency
    The identity of somatic and pluripotent cells can be epigenetically reprogrammed and forced to adapt a new functional cell state by different methods and distinct combinations of exogenous fa...
    Speaker: Jacob Hanna
    Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
    4
    JUL 01, 2017 | 8:00 AM
    Industry uses of human pluripotent stem cells
    Industry uses of human pluripotent stem cells
    Human pluripotent stem cells (hPSCs) and their derivatives are increasingly being used in industry to gain a competitive edge in drug discovery and a new wave of biotechnology start-up compan...
    Speaker: Stuart Chambers
    Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
    2
    JUL 01, 2017 | 8:00 AM
    Braingineering's human midbrain organoids as novel model for neurodegenerative diseases
    Braingineering's human midbrain organoids as novel model for neurodegenerative...
    Research on human brain development and neurological diseases is limited by the lack of advanced experimental in vitro models that truly recapitulate the complexity of the human brain. Here, ...
    Speaker: Jens Schwamborn
    Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
    2
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