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    Complex Disease

    Caused by genetic, environmental, and lifestyle factors, complex diseases such as asthma, diabetes, epilepsy, hypertension, manic depression, schizophrenia, and others, are often difficult to treat. Disorders that are commonly referenced as "running in the family" can be classified as complex diseases.

    Webinars

    • JUN 12, 2020 | 8:00 AM
      Genome imaging of head and neck solid tumors: oropharyngeal, tongue, and thyroid cancers
      Genome imaging of head and neck solid tumors: oropharyngeal, tongue,...
      DATE: June 12, 2020 TIME: 08:00 am PDT, 11:00 am EDT Whole genome imaging using the Saphyr instrument from Bionano detects structural variants (SVs), such as insertions, deletions,...
      Speaker: Brandon LaBarge
      Sponsored By: Bionano
      21
      JUN 03, 2020 | 12:00 PM
      Single cell multiomic analysis of T-cell exhaustion
      Single cell multiomic analysis of T-cell exhaustion
      A key step in the clinical production of CAR T cells is the expansion of engineered T cells. To generate enough cells for viable adoptive cell therapy, cells must be robustly stimulated, whi...
      Speaker: Pratip K. Chattopadhyay
      Presented at: Immuno-Oncology Virtual Event Series 2020
      Sponsored By: BD
      2
      JUN 03, 2020 | 12:00 PM
      How multiplexed imaging reveals key insights into the tumor microenvironment to inform treatment and improve outcomes
      How multiplexed imaging reveals key insights into the tumor microenvironment...
      Multiplexed immunofluorescent imaging sheds new light on cancer and other complex conditions. This imaging technique offers a deeper understanding of cells and their surroundings by providin...
      Speaker: Paul Goodwin , Fiona Ginty , Prachi Bogetto
      Presented at: Immuno-Oncology Virtual Event Series 2020
      Sponsored By: Cytiva
      0
      JUN 03, 2020 | 9:30 AM
      Keynote Presentation: The Importance of Tissue Chemistry in Immunity-Oncology
      Keynote Presentation: The Importance of Tissue Chemistry in Immunity-Oncology
      Cancer cells can acquire immune resistance resulting in a loss of immunosurveillance. Tumor cells can upregulate PDL-1 which binds to PD-1. This complex inhibits CD8 Tumor Infiltrating cells...
      Speaker: Thomas M. Grogan, MD
      Presented at: Immuno-Oncology Virtual Event Series 2020
      Sponsored By: Roche Diagnostics
      1
      MAY 27, 2020 | 8:00 AM
      How multiplexed imaging reveals key insights into the tumor microenvironment to inform treatment and improve outcomes
      How multiplexed imaging reveals key insights into the tumor microenvironment...
      DATE: May 27, 2020 TIME: 8:00am PT, 11:00am ET Multiplexed immunofluorescent imaging sheds new light on cancer and other complex conditions. This imaging technique offers a deeper understand...
      Speaker: Paul Goodwin , Fiona Ginty , Prachi Bogetto
      Sponsored By: Cytiva
      18 2
      MAY 20, 2020 | 12:00 AM
      The Importance of Data Integrity: LIMS, Tools and Best Practices
      The Importance of Data Integrity: LIMS, Tools and Best Practices
      The amount of data that is produced each day is mind boggling. Over 2.5 quintillion bytes of data are created every single day, and this number continues to grow every single day. This year...
      Speaker: Christine Paszko, PhD, MT (ASCP)
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      3
      MAY 20, 2020 | 12:00 AM
      Comprehensive Genomic Association Data for Genetic Variant Interpretation: A Computational Approach
      Comprehensive Genomic Association Data for Genetic Variant Interpretation:...
      Design and interpretation of genome sequencing assays and data in both clinical diagnostics and research labs is complicated by an inability to identify information from the medical literatu...
      Speaker: Mark Kiel, MD, PhD
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 20, 2020 | 12:00 AM
      Single-cell Genomics Tools for better understanding and treatment of Human Disease
      Single-cell Genomics Tools for better understanding and treatment...
      The basic units of biological structure and function are cells, which exhibit wide variation in regard to both type and state. We assess such variation by simultaneously profiling the transc...
      Speaker: Anindita Basu, PhD
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      2
      MAY 14, 2020 | 2:40 PM
      Oncomine Precision Assay on Ion Torrent Genexus System for liquid biopsy sample
      Oncomine Precision Assay on Ion Torrent Genexus System for liquid...
      Molecular profiling is key in precision oncology research and whilst the tissue testing has become a routine, liquid biopsy might provide a non-invasive alternative when tissue biopsy is ina...
      Speaker: Siew-Kee (Amanda) Low, PhD
      Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
      8
      MAY 14, 2020 | 2:40 PM
      Oncomine Precision Assay on Ion Torrent Genexus System for liquid biopsy sample
      Oncomine Precision Assay on Ion Torrent Genexus System for liquid...
      The development of molecular targeted therapy is one of the breakthroughs in oncology field. Molecular profiling of the tumor becomes mandatory in the routine clinical practice to select the...
      Speaker: Siew-Kee (Amanda) Low, PhD
      Presented at: OncomineWorld Autumn: A virtual NGS education meeting
      1
      MAY 12, 2020 | 9:00 AM
      Analytical Quality Control for the Pharmaceutical Industry
      Analytical Quality Control for the Pharmaceutical Industry
      NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
      Speaker: Joy McElroy
      Sponsored By: Sartorius
      29 9
      MAY 08, 2020 | 10:00 AM
      TCR-seq & BCR-seq Solutions: Applications to Clinical Research Projects
      TCR-seq & BCR-seq Solutions: Applications to Clinical Research...
      DATE: May 8, 2020 TIME: 10:00am PT, 11:00am MT, 1:00pm ET The application of next generation sequencing to interrogate immune repertoires and methods in which these highly complex dataset...
      Speaker: Brian O'Connor, PhD
      Sponsored By: Thermo Fisher Scientific - Ion Torrent
      16 10
      APR 29, 2020 | 6:00 AM
      Parsing Complex Disorders of the Gut-Immune-Brain Axis Into Clinically Meaningful Subsets: Immune Signatures as a Lens for Discovery
      Parsing Complex Disorders of the Gut-Immune-Brain Axis Into Clinically...
      ...
      Speaker: Mady Hornig, MA, MD
      Presented at: xMAP® Connect Virtual Conference (On-Demand)
      2
      APR 24, 2020 | 9:00 AM
      Deep Immune Profiling of Peripheral Blood Mononuclear Cells (PBMCs) with the CODEX® Platform
      Deep Immune Profiling of Peripheral Blood Mononuclear Cells (PBMCs)...
      DATE: April 24, 2020 TIME: 9:00am PT, 12:00pm ET Single-cell analysis of cell suspensions is increasingly important in studies of infectious diseases, cancer and autoimmune disorders, given...
      Speaker: Jon Mulholland, MS , Anum Khan, PhD , Oliver Braubach, Ph.D.
      Sponsored By: Akoya Biosciences
      6
      APR 22, 2020 | 12:00 AM
      Rapid Diagnosis of Complex Rare Disease Cases Using Exome Sequencing
      Rapid Diagnosis of Complex Rare Disease Cases Using Exome Sequencing
      Achieving a diagnosis in rare disease patients can be challenging for even the most experienced clinician or scientist, creating a barrier to delivering truly personalised care. An exome seq...
      Speaker: Louisa Ive, MSc HCPC
      Presented at: Genetics Week Virtual Event Series 2020
      2
      APR 22, 2020 | 12:00 AM
      Long-range technologies resolve complex genomic regions overlooked by short-read sequencing
      Long-range technologies resolve complex genomic regions overlooked...
      Complex genomes, including the human genome, contain ‘dark’ regions that standard short-read sequencing technologies do not adequately resolve—overlooking many variants tha...
      Speaker: Mark Ebbert, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 21, 2020 | 1:30 PM
      Spatially Resolved Molecular Investigation of Triple Negative Breast Cancer
      Spatially Resolved Molecular Investigation of Triple Negative...
      Triple-negative breast cancer (TNBC) is an aggressive disease that accounts for 10-20% of all breast cancer cases diagnosed annually in the U.S.1. Despite its prevalence, TNBC remains resist...
      Speaker: Dina Finan, PhD , Stephen Williams, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 21, 2020 | 7:30 AM
      Novel CRISPR Knock-In Technology for the Robust Analysis of Cells and Tissue
      Novel CRISPR Knock-In Technology for the Robust Analysis of Cells...
      Modern biomedical research is being driven by large scale genetic and proteomic research to identify new targets for the study of disease mechanisms. While these techniques have been incredi...
      Speaker: Scott Soderling, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      Sponsored By: CasTag Biosciences
      1 1
      APR 21, 2020 | 6:00 AM
      Advantages of digital PCR and its applications - the power of partitioning
      Advantages of digital PCR and its applications - the power of...
      The versatility of standard PCR and qPCR is well known. Digital PCR is now taking this to a whole new level. The power of partitioning enables you to explore new frontiers which have been li...
      Speaker: Daniel Löfgren, MSc.
      Presented at: Genetics Week Virtual Event Series 2020
      Sponsored By: QIAGEN
      1
      APR 21, 2020 | 12:00 AM
      Bionano Genome Imaging: unbiased, genome-wide structural variation detection in genetic disease and cancer, down to 1% allele fraction
      Bionano Genome Imaging: unbiased, genome-wide structural variation...
      Learning Objectives: 1. Learn why the complexity and repetitive structure of the human genome makes it impossible to detect all structural variants using short-read sequencing 2. Learn how h...
      Speaker: Sven Bocklandt, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      MAR 24, 2020 | 11:00 AM
      3-D Organoid Models for Differentiation of PSC-Derived Dopaminergic Neurons
      3-D Organoid Models for Differentiation of PSC-Derived Dopaminergic...
      DATE: March 24, 2020 TIME: 11:00am PT, 2:00pm ET While in vitro cell culture has long been used to study neurological diseases, researchers have come to the realization that 2-D systems do n...
      Speaker: Richard Josephson, PhD
      Sponsored By: Thermo Fisher Scientific - Disease Modeling
      9
      MAR 24, 2020 | 10:00 AM
      Save your time on data analysis with new Batch Analysis feature in Axon pCLAMP 11 Software
      Save your time on data analysis with new Batch Analysis feature...
      DATE: March 24, 2020 TIME: 10:00 am PDT, 1:00pm EDT The Clampfit software module is a useful tool to manipulate and analyze electrophysiological data acquired by pCLAMP™ software. Rece...
      Speaker: Jeffrey Tang, Ph.D.
      Sponsored By: Molecular Devices
      10
      MAR 05, 2020 | 9:00 AM
      An Update on H. pylori testing with a focus on the Houston Consensus recommendations
      An Update on H. pylori testing with a focus on the Houston Consensus...
      Recommendations for key factors in testing and diagnosis of H. pylori infections to include information on appropriate patients for H.pylori testing, current testing options, post treatment...
      Speaker: David Graham, MD
      8
      FEB 26, 2020 | 9:00 AM
      The use of 3D Models in Hepatic Biology
      The use of 3D Models in Hepatic Biology
      DATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...
      Speaker: Julia Tritapoe , David Kuninger, PhD
      Sponsored By: Thermo Fisher Scientific
      12 1
    JUN 12, 2020 | 8:00 AM
    Genome imaging of head and neck solid tumors: oropharyngeal, tongue, and thyroid cancers
    Genome imaging of head and neck solid tumors: oropharyngeal, tongue,...
    DATE: June 12, 2020 TIME: 08:00 am PDT, 11:00 am EDT Whole genome imaging using the Saphyr instrument from Bionano detects structural variants (SVs), such as insertions, deletions,...
    Speaker: Brandon LaBarge
    Sponsored By: Bionano
    21
    JUN 03, 2020 | 12:00 PM
    Single cell multiomic analysis of T-cell exhaustion
    Single cell multiomic analysis of T-cell exhaustion
    A key step in the clinical production of CAR T cells is the expansion of engineered T cells. To generate enough cells for viable adoptive cell therapy, cells must be robustly stimulated, whi...
    Speaker: Pratip K. Chattopadhyay
    Presented at: Immuno-Oncology Virtual Event Series 2020
    Sponsored By: BD
    2
    JUN 03, 2020 | 12:00 PM
    How multiplexed imaging reveals key insights into the tumor microenvironment to inform treatment and improve outcomes
    How multiplexed imaging reveals key insights into the tumor microenvironment...
    Multiplexed immunofluorescent imaging sheds new light on cancer and other complex conditions. This imaging technique offers a deeper understanding of cells and their surroundings by providin...
    Speaker: Paul Goodwin , Fiona Ginty , Prachi Bogetto
    Presented at: Immuno-Oncology Virtual Event Series 2020
    Sponsored By: Cytiva
    0
    JUN 03, 2020 | 9:30 AM
    Keynote Presentation: The Importance of Tissue Chemistry in Immunity-Oncology
    Keynote Presentation: The Importance of Tissue Chemistry in Immunity-Oncology
    Cancer cells can acquire immune resistance resulting in a loss of immunosurveillance. Tumor cells can upregulate PDL-1 which binds to PD-1. This complex inhibits CD8 Tumor Infiltrating cells...
    Speaker: Thomas M. Grogan, MD
    Presented at: Immuno-Oncology Virtual Event Series 2020
    Sponsored By: Roche Diagnostics
    1
    MAY 27, 2020 | 8:00 AM
    How multiplexed imaging reveals key insights into the tumor microenvironment to inform treatment and improve outcomes
    How multiplexed imaging reveals key insights into the tumor microenvironment...
    DATE: May 27, 2020 TIME: 8:00am PT, 11:00am ET Multiplexed immunofluorescent imaging sheds new light on cancer and other complex conditions. This imaging technique offers a deeper understand...
    Speaker: Paul Goodwin , Fiona Ginty , Prachi Bogetto
    Sponsored By: Cytiva
    18 2
     
     
  • MAY 20, 2020 | 12:00 AM
    The Importance of Data Integrity: LIMS, Tools and Best Practices
    The Importance of Data Integrity: LIMS, Tools and Best Practices
    The amount of data that is produced each day is mind boggling. Over 2.5 quintillion bytes of data are created every single day, and this number continues to grow every single day. This year...
    Speaker: Christine Paszko, PhD, MT (ASCP)
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    3
    MAY 20, 2020 | 12:00 AM
    Comprehensive Genomic Association Data for Genetic Variant Interpretation: A Computational Approach
    Comprehensive Genomic Association Data for Genetic Variant Interpretation:...
    Design and interpretation of genome sequencing assays and data in both clinical diagnostics and research labs is complicated by an inability to identify information from the medical literatu...
    Speaker: Mark Kiel, MD, PhD
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
    MAY 20, 2020 | 12:00 AM
    Single-cell Genomics Tools for better understanding and treatment of Human Disease
    Single-cell Genomics Tools for better understanding and treatment...
    The basic units of biological structure and function are cells, which exhibit wide variation in regard to both type and state. We assess such variation by simultaneously profiling the transc...
    Speaker: Anindita Basu, PhD
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    2
    MAY 14, 2020 | 2:40 PM
    Oncomine Precision Assay on Ion Torrent Genexus System for liquid biopsy sample
    Oncomine Precision Assay on Ion Torrent Genexus System for liquid...
    Molecular profiling is key in precision oncology research and whilst the tissue testing has become a routine, liquid biopsy might provide a non-invasive alternative when tissue biopsy is ina...
    Speaker: Siew-Kee (Amanda) Low, PhD
    Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
    8
    MAY 14, 2020 | 2:40 PM
    Oncomine Precision Assay on Ion Torrent Genexus System for liquid biopsy sample
    Oncomine Precision Assay on Ion Torrent Genexus System for liquid...
    The development of molecular targeted therapy is one of the breakthroughs in oncology field. Molecular profiling of the tumor becomes mandatory in the routine clinical practice to select the...
    Speaker: Siew-Kee (Amanda) Low, PhD
    Presented at: OncomineWorld Autumn: A virtual NGS education meeting
    1
     
     
  • MAY 12, 2020 | 9:00 AM
    Analytical Quality Control for the Pharmaceutical Industry
    Analytical Quality Control for the Pharmaceutical Industry
    NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
    Speaker: Joy McElroy
    Sponsored By: Sartorius
    29 9
    MAY 08, 2020 | 10:00 AM
    TCR-seq & BCR-seq Solutions: Applications to Clinical Research Projects
    TCR-seq & BCR-seq Solutions: Applications to Clinical Research...
    DATE: May 8, 2020 TIME: 10:00am PT, 11:00am MT, 1:00pm ET The application of next generation sequencing to interrogate immune repertoires and methods in which these highly complex dataset...
    Speaker: Brian O'Connor, PhD
    Sponsored By: Thermo Fisher Scientific - Ion Torrent
    16 10
    APR 29, 2020 | 6:00 AM
    Parsing Complex Disorders of the Gut-Immune-Brain Axis Into Clinically Meaningful Subsets: Immune Signatures as a Lens for Discovery
    Parsing Complex Disorders of the Gut-Immune-Brain Axis Into Clinically...
    ...
    Speaker: Mady Hornig, MA, MD
    Presented at: xMAP® Connect Virtual Conference (On-Demand)
    2
    APR 24, 2020 | 9:00 AM
    Deep Immune Profiling of Peripheral Blood Mononuclear Cells (PBMCs) with the CODEX® Platform
    Deep Immune Profiling of Peripheral Blood Mononuclear Cells (PBMCs)...
    DATE: April 24, 2020 TIME: 9:00am PT, 12:00pm ET Single-cell analysis of cell suspensions is increasingly important in studies of infectious diseases, cancer and autoimmune disorders, given...
    Speaker: Jon Mulholland, MS , Anum Khan, PhD , Oliver Braubach, Ph.D.
    Sponsored By: Akoya Biosciences
    6
    APR 22, 2020 | 12:00 AM
    Rapid Diagnosis of Complex Rare Disease Cases Using Exome Sequencing
    Rapid Diagnosis of Complex Rare Disease Cases Using Exome Sequencing
    Achieving a diagnosis in rare disease patients can be challenging for even the most experienced clinician or scientist, creating a barrier to delivering truly personalised care. An exome seq...
    Speaker: Louisa Ive, MSc HCPC
    Presented at: Genetics Week Virtual Event Series 2020
    2
     
     
  • APR 22, 2020 | 12:00 AM
    Long-range technologies resolve complex genomic regions overlooked by short-read sequencing
    Long-range technologies resolve complex genomic regions overlooked...
    Complex genomes, including the human genome, contain ‘dark’ regions that standard short-read sequencing technologies do not adequately resolve—overlooking many variants tha...
    Speaker: Mark Ebbert, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 21, 2020 | 1:30 PM
    Spatially Resolved Molecular Investigation of Triple Negative Breast Cancer
    Spatially Resolved Molecular Investigation of Triple Negative...
    Triple-negative breast cancer (TNBC) is an aggressive disease that accounts for 10-20% of all breast cancer cases diagnosed annually in the U.S.1. Despite its prevalence, TNBC remains resist...
    Speaker: Dina Finan, PhD , Stephen Williams, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 21, 2020 | 7:30 AM
    Novel CRISPR Knock-In Technology for the Robust Analysis of Cells and Tissue
    Novel CRISPR Knock-In Technology for the Robust Analysis of Cells...
    Modern biomedical research is being driven by large scale genetic and proteomic research to identify new targets for the study of disease mechanisms. While these techniques have been incredi...
    Speaker: Scott Soderling, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    Sponsored By: CasTag Biosciences
    1 1
    APR 21, 2020 | 6:00 AM
    Advantages of digital PCR and its applications - the power of partitioning
    Advantages of digital PCR and its applications - the power of...
    The versatility of standard PCR and qPCR is well known. Digital PCR is now taking this to a whole new level. The power of partitioning enables you to explore new frontiers which have been li...
    Speaker: Daniel Löfgren, MSc.
    Presented at: Genetics Week Virtual Event Series 2020
    Sponsored By: QIAGEN
    1
    APR 21, 2020 | 12:00 AM
    Bionano Genome Imaging: unbiased, genome-wide structural variation detection in genetic disease and cancer, down to 1% allele fraction
    Bionano Genome Imaging: unbiased, genome-wide structural variation...
    Learning Objectives: 1. Learn why the complexity and repetitive structure of the human genome makes it impossible to detect all structural variants using short-read sequencing 2. Learn how h...
    Speaker: Sven Bocklandt, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
     
     
  • MAR 24, 2020 | 11:00 AM
    3-D Organoid Models for Differentiation of PSC-Derived Dopaminergic Neurons
    3-D Organoid Models for Differentiation of PSC-Derived Dopaminergic...
    DATE: March 24, 2020 TIME: 11:00am PT, 2:00pm ET While in vitro cell culture has long been used to study neurological diseases, researchers have come to the realization that 2-D systems do n...
    Speaker: Richard Josephson, PhD
    Sponsored By: Thermo Fisher Scientific - Disease Modeling
    9
    MAR 24, 2020 | 10:00 AM
    Save your time on data analysis with new Batch Analysis feature in Axon pCLAMP 11 Software
    Save your time on data analysis with new Batch Analysis feature...
    DATE: March 24, 2020 TIME: 10:00 am PDT, 1:00pm EDT The Clampfit software module is a useful tool to manipulate and analyze electrophysiological data acquired by pCLAMP™ software. Rece...
    Speaker: Jeffrey Tang, Ph.D.
    Sponsored By: Molecular Devices
    10
    MAR 05, 2020 | 9:00 AM
    An Update on H. pylori testing with a focus on the Houston Consensus recommendations
    An Update on H. pylori testing with a focus on the Houston Consensus...
    Recommendations for key factors in testing and diagnosis of H. pylori infections to include information on appropriate patients for H.pylori testing, current testing options, post treatment...
    Speaker: David Graham, MD
    8
    FEB 26, 2020 | 9:00 AM
    The use of 3D Models in Hepatic Biology
    The use of 3D Models in Hepatic Biology
    DATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...
    Speaker: Julia Tritapoe , David Kuninger, PhD
    Sponsored By: Thermo Fisher Scientific
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