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    Complex Disease

    Caused by genetic, environmental, and lifestyle factors, complex diseases such as asthma, diabetes, epilepsy, hypertension, manic depression, schizophrenia, and others, are often difficult to treat. Disorders that are commonly referenced as "running in the family" can be classified as complex diseases.

    Webinars

    • JAN 14, 2020 | 9:00 AM
      Fecal Elastase-1 - a Biomarker for Pancreatic Exocrine Insufficiency
      Fecal Elastase-1 - a Biomarker for Pancreatic Exocrine Insufficiency
      Fecal elastase-1 – a biomarker for pancreatic exocrine insufficiency(EPI) continues to gain traction as an ideal biomarker for assessing EPI. This presentation will include a review of...
      Speaker: Roy Sherwood, BSc, MSC, DPhil
      Sponsored By: Diasorin S.p.A.
      5
      JAN 14, 2020 | 8:00 AM
      CiPA initiative and validation of high-throughput methods to characterize compound effects in human iPSC-derived cardiomyocytes
      CiPA initiative and validation of high-throughput methods to characterize...
      DATE: January 14, 2019 TIME: 8:00am PST Drug-induced QT interval prolongation and Torsades de Pointes (TdP) arrhythmias are the leading causes for drug withdrawals from market and compound a...
      Speaker: Muthukrishnan Renganathan, PhD , Panida Lertkiatmongkol, PhD , Oksana Sirenko, PhD , Carole Crittenden
      Sponsored By: Molecular Devices, Eurofins Discovery
      3
      JAN 01, 2020 | 6:00 AM
      Microphysiological Systems for Human Focused Drug Discovery
      Microphysiological Systems for Human Focused Drug Discovery
      Microphysiological systems (MPS), also known as organ-on-chips, are small scale in vitro cell cultures which mimic facets of tissue or organ level function. MPS frequently utilise primary hu...
      Speaker: Tomasz Kostrzewski, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      3
      JAN 01, 2020 | 6:00 AM
      3D-Micro Tissues in Translational Toxicology and Disease Modelling
      3D-Micro Tissues in Translational Toxicology and Disease Modelling
      The aim of the lecture is to give an insight into the use of 3D liver micro tissues (3D liMTs) in drug discovery and translational safety. In translational toxicology, 3D LiMTs have a high i...
      Speaker: Armin Wolf, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      JAN 01, 2020 | 6:00 AM
      Using 3D cell culture models and high content confocal imaging to evaluate efficacy and expose toxic liabilities in the drug development pipeline
      Using 3D cell culture models and high content confocal imaging...
      With an increasing push to improve safety, efficacy, and efficiency throughout the drug development pipeline, researchers are evermore looking to improve the predictive capacity of their in...
      Speaker: Erin Edwards, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      NOV 14, 2019 | 1:30 PM
      Strategies to Improve Laboratory Stewardship
      Strategies to Improve Laboratory Stewardship
      The Laboratory Stewardship Committee of the Cleveland Clinic is a multidisciplinary team of clinicians, pathologists, administrators, nurses and other caregivers. The team has a commitment t...
      Speaker: Gary Procop, MD, MS
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
      3
      NOV 13, 2019 | 8:00 AM
      The power and generality of single-cell studies
      The power and generality of single-cell studies
      DATE: November 13, 2019TIME: 8:00am PSTIn this presentation, Dr. Rizvi will outline the power and generality of single-cell studies, workflows enabling such studies, and skillful mean...
      Speaker: Dr. Abbas Rizvi
      Sponsored By: Beckman Coulter Life Sciences
      7
      NOV 12, 2019 | 10:00 AM
      Leveraging single cell copy number to resolve tumor clonality
      Leveraging single cell copy number to resolve tumor clonality
      DATE: November 12, 2019TIME: 10:00am PSTDirect measurement of copy number by droplet-based shallow sequencing of genomic DNA has the potential to provide new insights into tumor heterog...
      Speaker: Dr. David Craig
      Sponsored By: 10x Genomics
      9 1
      NOV 07, 2019 | 10:00 AM
      Akoya Biosciences Webinar Series: Validating Multiplexed Antibody Panels for Pancreatic Research Applications
      Akoya Biosciences Webinar Series: Validating Multiplexed Antibody...
      DATE: November 7, 2019TIME: 10:00am PST, 1:00pm EST Studying the pathogenesis of diabetes requires detailed analysis of the pancreatic islet microenvironment and its numerous c...
      Speaker: Diane Saunders, PhD , Grady Carlson, PhD
      Sponsored By: Akoya Biosciences
      5
      NOV 06, 2019 | 12:00 PM
      A dose of the flu: influenza's variable virus particles
      A dose of the flu: influenza's variable virus particles
      Influenza viruses are transmitted by membrane-bound virus particles, or virions. Unlike some viruses, which produce near-identical virions from a well-defined set of viral components, influen...
      Speaker: Edward Hutchinson, PhD
      Presented at: Influenza Virtual Event Series 2019
      4 2
      NOV 06, 2019 | 6:00 AM
      Understanding the Pathogenesis of Human Influenza Virus: A Systems Virology Approach
      Understanding the Pathogenesis of Human Influenza Virus: A Systems...
      Multiple factors can affect and impact infection dynamics and virulence produced by influenza virus (IV) infections. Susceptibility factors and host responses can also have major effects in d...
      Speaker: Rafael Medina Silva, PhD
      Presented at: Influenza Virtual Event Series 2019
      1
      OCT 29, 2019 | 8:00 AM
      Multi-omics Approach to Understanding PD-L1 Resistance in Cancer
      Multi-omics Approach to Understanding PD-L1 Resistance in Cancer
      DATE: October 29, 2019TIME: 8:00am PDTAlthough immune-based therapies targeting the inhibitory receptors (PD-L1, PD1, and CTLA4) are proven to be effective to treat cancer, some pati...
      Speaker: Moshe Sade Feldman (PhD) , Russell Jenkins MD, PhD
      Sponsored By: Sony Biotechnology
      8
      OCT 15, 2019 | 10:00 AM
      The 'Three Peak Challenge' for long-read, ultra-deep stool metagenomics on the PromethION
      The 'Three Peak Challenge' for long-read, ultra-deep stool metagenomics...
      DATE: October 15, 2019TIME: 10:00am PDTAdvances in Next-Generation Sequencing technologies as well as bioinformatic tools have advanced our ability to research and explore both human...
      Speaker: Josh Quick , Janina A. Krumbeck, PhD.
      Sponsored By: Zymo Research
      12
      OCT 10, 2019 | 10:30 AM
      Transcriptional Profiling of the Pediatric Tumor Microenvironment
      Transcriptional Profiling of the Pediatric Tumor Microenvironment
      Osteosarcoma (OS) is the most common bone tumor in pediatric and adolescent/young adult patients. Over the past three decades, significant improvements in the survival rates or therapeutic ap...
      Speaker: Troy McEachron, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      Sponsored By: NanoString Technologies
      1
      OCT 10, 2019 | 10:30 AM
      Whole genome imaging for sensitive and accurate analysis of structural variations in cancer
      Whole genome imaging for sensitive and accurate analysis of structural...
      Accumulation of structural variations (SVs) across the genome is a known trigger factor for oncogenesis. Structural mutations have been clearly implicated in a number of cancers, most notably...
      Speaker: Sven Bocklandt, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      Sponsored By: Bionano
      1
      OCT 10, 2019 | 9:00 AM
      Dynamic evolution of unstable genomes: insights from in vitro experiments and cancer genome analysis
      Dynamic evolution of unstable genomes: insights from in vitro...
      Copy-number alterations and chromosomal translocations are widespread in cancer and frequently causing oncogenic mutations that drive tumorigenesis and therapy resistance. Despite their preva...
      Speaker: Cheng-Zhong Zhang, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      1
      SEP 27, 2019 | 9:00 AM
      Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
      Investigating how Tpz-1 may be used as a novel therapeutic agent...
      DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
      Speaker: Jessica Hess
      Sponsored By: Thermo Fisher Scientific/Gibco
      5
      SEP 26, 2019 | 10:30 AM
      Discover the genes that matter while preserving spatial information: The Visium Gene Expression Solution
      Discover the genes that matter while preserving spatial information:...
      The ability to discern spatial gene expression differences in complex biological systems is critical to our understanding of developmental biology and the progression of disease. However, the...
      Speaker: Nikhil Rao
      Presented at: Cell Biology Virtual Event Series 2019
      1
      SEP 19, 2019 | 8:00 AM
      Importance and Role of Biomarkers in the Management of Pediatric Inflammatory Disease
      Importance and Role of Biomarkers in the Management of Pediatric...
      Learning Objectives: Review basic immuno-pathobiology of IBD and the phenotypes of IBD or IBDs - Crohn’s, Ulcerative Colitis and Indeterminate Colitis Briefly describe the epide...
      Speaker: Benjamin Gold, MD, FACG, FAAP
      Sponsored By: Diasorin
      4
      SEP 12, 2019 | 1:30 PM
      Gender Parity in Virology Conference Speaker Selections
      Gender Parity in Virology Conference Speaker Selections
      Scientific conferences are most beneficial to participants when they showcase significant new experimental developments, accurately summarize the current state of the field, and provide stron...
      Speaker: Ann Palmenberg, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2019
      1
      SEP 12, 2019 | 12:00 PM
      Multi-Omic Approaches for the Study of Vaginal Microbial Communities
      Multi-Omic Approaches for the Study of Vaginal Microbial Communities
      Vaginal microbial communities play an important role in women’s heath. It is now clear that the vaginal microbiome is linked to pregnancy complications such as preterm birth and risk f...
      Speaker: Jennifer Fettweis, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2019
      2
      SEP 12, 2019 | 7:30 AM
      Keynote Presentation: Microbial Centric Aging: A Paradigm Shift
      Keynote Presentation: Microbial Centric Aging: A Paradigm Shift
      ....
      Speaker: John Thomas, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2019
      2
      SEP 12, 2019 | 6:00 AM
      Using the NASA GeneLab Data System to Study the Metagenomes of Spaceships and Their Occupants
      Using the NASA GeneLab Data System to Study the Metagenomes of...
      With humans pushing to live further off Earth for longer periods of time, it is increasingly important to understand the changes that occur in biological systems during spaceflight whether th...
      Speaker: Jonathan Galazka, PhD , Daniela Bezdan, PhD , Peng Jiang, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2019
      1
      SEP 11, 2019 | 1:30 PM
      Development of Machine Learning Algorithms to Data Mine Meta-Omic Characterizations of Complex Microbiota
      Development of Machine Learning Algorithms to Data Mine Meta-Omic...
      Background: The vast majority of all genes are contained within the genomes of the prokaryotes, including the eubacteria and the archaea. These largely single-cellular domains of life thus...
      Speaker: Garth Ehrlich, PhD, FAAAS
      Presented at: Microbiology & Immunology Virtual Event Series 2019
      Sponsored By: PacBio
      4
    JAN 14, 2020 | 9:00 AM
    Fecal Elastase-1 - a Biomarker for Pancreatic Exocrine Insufficiency
    Fecal Elastase-1 - a Biomarker for Pancreatic Exocrine Insufficiency
    Fecal elastase-1 – a biomarker for pancreatic exocrine insufficiency(EPI) continues to gain traction as an ideal biomarker for assessing EPI. This presentation will include a review of...
    Speaker: Roy Sherwood, BSc, MSC, DPhil
    Sponsored By: Diasorin S.p.A.
    5
    JAN 14, 2020 | 8:00 AM
    CiPA initiative and validation of high-throughput methods to characterize compound effects in human iPSC-derived cardiomyocytes
    CiPA initiative and validation of high-throughput methods to characterize...
    DATE: January 14, 2019 TIME: 8:00am PST Drug-induced QT interval prolongation and Torsades de Pointes (TdP) arrhythmias are the leading causes for drug withdrawals from market and compound a...
    Speaker: Muthukrishnan Renganathan, PhD , Panida Lertkiatmongkol, PhD , Oksana Sirenko, PhD , Carole Crittenden
    Sponsored By: Molecular Devices, Eurofins Discovery
    3
    JAN 01, 2020 | 6:00 AM
    Microphysiological Systems for Human Focused Drug Discovery
    Microphysiological Systems for Human Focused Drug Discovery
    Microphysiological systems (MPS), also known as organ-on-chips, are small scale in vitro cell cultures which mimic facets of tissue or organ level function. MPS frequently utilise primary hu...
    Speaker: Tomasz Kostrzewski, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    3
    JAN 01, 2020 | 6:00 AM
    3D-Micro Tissues in Translational Toxicology and Disease Modelling
    3D-Micro Tissues in Translational Toxicology and Disease Modelling
    The aim of the lecture is to give an insight into the use of 3D liver micro tissues (3D liMTs) in drug discovery and translational safety. In translational toxicology, 3D LiMTs have a high i...
    Speaker: Armin Wolf, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    JAN 01, 2020 | 6:00 AM
    Using 3D cell culture models and high content confocal imaging to evaluate efficacy and expose toxic liabilities in the drug development pipeline
    Using 3D cell culture models and high content confocal imaging...
    With an increasing push to improve safety, efficacy, and efficiency throughout the drug development pipeline, researchers are evermore looking to improve the predictive capacity of their in...
    Speaker: Erin Edwards, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
     
     
  • NOV 14, 2019 | 1:30 PM
    Strategies to Improve Laboratory Stewardship
    Strategies to Improve Laboratory Stewardship
    The Laboratory Stewardship Committee of the Cleveland Clinic is a multidisciplinary team of clinicians, pathologists, administrators, nurses and other caregivers. The team has a commitment t...
    Speaker: Gary Procop, MD, MS
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
    3
    NOV 13, 2019 | 8:00 AM
    The power and generality of single-cell studies
    The power and generality of single-cell studies
    DATE: November 13, 2019TIME: 8:00am PSTIn this presentation, Dr. Rizvi will outline the power and generality of single-cell studies, workflows enabling such studies, and skillful mean...
    Speaker: Dr. Abbas Rizvi
    Sponsored By: Beckman Coulter Life Sciences
    7
    NOV 12, 2019 | 10:00 AM
    Leveraging single cell copy number to resolve tumor clonality
    Leveraging single cell copy number to resolve tumor clonality
    DATE: November 12, 2019TIME: 10:00am PSTDirect measurement of copy number by droplet-based shallow sequencing of genomic DNA has the potential to provide new insights into tumor heterog...
    Speaker: Dr. David Craig
    Sponsored By: 10x Genomics
    9 1
    NOV 07, 2019 | 10:00 AM
    Akoya Biosciences Webinar Series: Validating Multiplexed Antibody Panels for Pancreatic Research Applications
    Akoya Biosciences Webinar Series: Validating Multiplexed Antibody...
    DATE: November 7, 2019TIME: 10:00am PST, 1:00pm EST Studying the pathogenesis of diabetes requires detailed analysis of the pancreatic islet microenvironment and its numerous c...
    Speaker: Diane Saunders, PhD , Grady Carlson, PhD
    Sponsored By: Akoya Biosciences
    5
    NOV 06, 2019 | 12:00 PM
    A dose of the flu: influenza's variable virus particles
    A dose of the flu: influenza's variable virus particles
    Influenza viruses are transmitted by membrane-bound virus particles, or virions. Unlike some viruses, which produce near-identical virions from a well-defined set of viral components, influen...
    Speaker: Edward Hutchinson, PhD
    Presented at: Influenza Virtual Event Series 2019
    4 2
     
     
  • NOV 06, 2019 | 6:00 AM
    Understanding the Pathogenesis of Human Influenza Virus: A Systems Virology Approach
    Understanding the Pathogenesis of Human Influenza Virus: A Systems...
    Multiple factors can affect and impact infection dynamics and virulence produced by influenza virus (IV) infections. Susceptibility factors and host responses can also have major effects in d...
    Speaker: Rafael Medina Silva, PhD
    Presented at: Influenza Virtual Event Series 2019
    1
    OCT 29, 2019 | 8:00 AM
    Multi-omics Approach to Understanding PD-L1 Resistance in Cancer
    Multi-omics Approach to Understanding PD-L1 Resistance in Cancer
    DATE: October 29, 2019TIME: 8:00am PDTAlthough immune-based therapies targeting the inhibitory receptors (PD-L1, PD1, and CTLA4) are proven to be effective to treat cancer, some pati...
    Speaker: Moshe Sade Feldman (PhD) , Russell Jenkins MD, PhD
    Sponsored By: Sony Biotechnology
    8
    OCT 15, 2019 | 10:00 AM
    The 'Three Peak Challenge' for long-read, ultra-deep stool metagenomics on the PromethION
    The 'Three Peak Challenge' for long-read, ultra-deep stool metagenomics...
    DATE: October 15, 2019TIME: 10:00am PDTAdvances in Next-Generation Sequencing technologies as well as bioinformatic tools have advanced our ability to research and explore both human...
    Speaker: Josh Quick , Janina A. Krumbeck, PhD.
    Sponsored By: Zymo Research
    12
    OCT 10, 2019 | 10:30 AM
    Transcriptional Profiling of the Pediatric Tumor Microenvironment
    Transcriptional Profiling of the Pediatric Tumor Microenvironment
    Osteosarcoma (OS) is the most common bone tumor in pediatric and adolescent/young adult patients. Over the past three decades, significant improvements in the survival rates or therapeutic ap...
    Speaker: Troy McEachron, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    Sponsored By: NanoString Technologies
    1
    OCT 10, 2019 | 10:30 AM
    Whole genome imaging for sensitive and accurate analysis of structural variations in cancer
    Whole genome imaging for sensitive and accurate analysis of structural...
    Accumulation of structural variations (SVs) across the genome is a known trigger factor for oncogenesis. Structural mutations have been clearly implicated in a number of cancers, most notably...
    Speaker: Sven Bocklandt, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    Sponsored By: Bionano
    1
     
     
  • OCT 10, 2019 | 9:00 AM
    Dynamic evolution of unstable genomes: insights from in vitro experiments and cancer genome analysis
    Dynamic evolution of unstable genomes: insights from in vitro...
    Copy-number alterations and chromosomal translocations are widespread in cancer and frequently causing oncogenic mutations that drive tumorigenesis and therapy resistance. Despite their preva...
    Speaker: Cheng-Zhong Zhang, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    1
    SEP 27, 2019 | 9:00 AM
    Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
    Investigating how Tpz-1 may be used as a novel therapeutic agent...
    DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
    Speaker: Jessica Hess
    Sponsored By: Thermo Fisher Scientific/Gibco
    5
    SEP 26, 2019 | 10:30 AM
    Discover the genes that matter while preserving spatial information: The Visium Gene Expression Solution
    Discover the genes that matter while preserving spatial information:...
    The ability to discern spatial gene expression differences in complex biological systems is critical to our understanding of developmental biology and the progression of disease. However, the...
    Speaker: Nikhil Rao
    Presented at: Cell Biology Virtual Event Series 2019
    1
    SEP 19, 2019 | 8:00 AM
    Importance and Role of Biomarkers in the Management of Pediatric Inflammatory Disease
    Importance and Role of Biomarkers in the Management of Pediatric...
    Learning Objectives: Review basic immuno-pathobiology of IBD and the phenotypes of IBD or IBDs - Crohn’s, Ulcerative Colitis and Indeterminate Colitis Briefly describe the epide...
    Speaker: Benjamin Gold, MD, FACG, FAAP
    Sponsored By: Diasorin
    4
    SEP 12, 2019 | 1:30 PM
    Gender Parity in Virology Conference Speaker Selections
    Gender Parity in Virology Conference Speaker Selections
    Scientific conferences are most beneficial to participants when they showcase significant new experimental developments, accurately summarize the current state of the field, and provide stron...
    Speaker: Ann Palmenberg, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2019
    1
     
     
  • SEP 12, 2019 | 12:00 PM
    Multi-Omic Approaches for the Study of Vaginal Microbial Communities
    Multi-Omic Approaches for the Study of Vaginal Microbial Communities
    Vaginal microbial communities play an important role in women’s heath. It is now clear that the vaginal microbiome is linked to pregnancy complications such as preterm birth and risk f...
    Speaker: Jennifer Fettweis, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2019
    2
    SEP 12, 2019 | 7:30 AM
    Keynote Presentation: Microbial Centric Aging: A Paradigm Shift
    Keynote Presentation: Microbial Centric Aging: A Paradigm Shift
    ....
    Speaker: John Thomas, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2019
    2
    SEP 12, 2019 | 6:00 AM
    Using the NASA GeneLab Data System to Study the Metagenomes of Spaceships and Their Occupants
    Using the NASA GeneLab Data System to Study the Metagenomes of...
    With humans pushing to live further off Earth for longer periods of time, it is increasingly important to understand the changes that occur in biological systems during spaceflight whether th...
    Speaker: Jonathan Galazka, PhD , Daniela Bezdan, PhD , Peng Jiang, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2019
    1
    SEP 11, 2019 | 1:30 PM
    Development of Machine Learning Algorithms to Data Mine Meta-Omic Characterizations of Complex Microbiota
    Development of Machine Learning Algorithms to Data Mine Meta-Omic...
    Background: The vast majority of all genes are contained within the genomes of the prokaryotes, including the eubacteria and the archaea. These largely single-cellular domains of life thus...
    Speaker: Garth Ehrlich, PhD, FAAAS
    Presented at: Microbiology & Immunology Virtual Event Series 2019
    Sponsored By: PacBio
    4
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