Dopamine
Dopamine is a neurotransmitter, one of those chemicals that is responsible for transmitting signals in between the nerve cells (neurons) of the brain. Very few neurons actually make dopamine. Some, in a part of the brain called the substantia nigra, are the cells that die during Parkinsons disease. The functions of others, located in a part of the brain called the ventral tegmental area (VTA), are less well defined and are the major source of the aforementioned controversy (and the focus of this post). When dopamine neurons become activated, they release dopamine.
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MAR 11, 2020 3:00 PM PDTC.E. CREDITS
MAR 11, 2020 3:00 PM PDTWorking memory (the ability to hold some information in mind for a few seconds, and to manipulate that information) and decision-making (committing to one out of multiple possible choices) a...Speaker: Carlos Brody, PhD , Ben Engelhard, PhD , Stephen Keeley, PhD , Marlies Oostland, PhD , Lucas Pinto, MD, PhD , Adrian Wanner, PhD , Ilana Witten, PhDPresented at: Neuroscience 2020MAR 11, 2020 1:30 PM PDTC.E. CREDITS
MAR 11, 2020 1:30 PM PDTLearning is often an emotional process. Emotional stimuli with different valences, such as threat and reward, can transform an otherwise neutral sensory input into one that can trigger disti...Speaker: Bo Li , Tianyi Mao , Haining ZhongPresented at: Neuroscience 2020MAR 11, 2020 6:00 AM PDTC.E. CREDITS
MAR 11, 2020 6:00 AM PDTWe present here a framework to generate a realistic multiscale circuit model of the larval zebrafish brain – the multiscale virtual fish (MVF). The model will be based on algorithms in...Speaker: Florian Engert, PhD , Jeff Lichtman, MD, PhD , Haim SompolinskyPresented at: Neuroscience 2020C.E. CREDITS
The dopamine D4 receptor (D4R) is enriched in the prefrontal cortex where it plays important roles in cognition, attention, decision making and executive function. Novel D4R-selective ligand...Speaker: Comfort Boateng, PhDPresented at: Neuroscience 2020C.E. CREDITS
Striatal neuromodulation through G-protein-coupled receptors (GPCRs) regulates complex voluntary motor actions, involving decision-making, learning, and action selection. The dorsal striatum...Speaker: Shana Augustin, PhDPresented at: Neuroscience 2020FEB 27, 2019 8:00 AM PSTC.E. CREDITS
FEB 27, 2019 8:00 AM PSTDATE: February 27, 2019TIME: 8:00am PST Pluripotent stem cells (PSCs) can form any tissue or cell in the body, and are the ideal starting material to manufacture...Speaker: Benjamin FryerSponsored By: Thermo Fisher Scientific/GibcoDEC 06, 2018 9:00 AM PST
DEC 06, 2018 9:00 AM PSTDATE: December 6, 2018TIME: 9:00am PST, 12:00pm EST Induced pluripotent stem cells (iPSC) intended for translational applications need to be of...Speaker: Tia Hexom, PhDSponsored By: Thermo Fisher Scientific/GibcoMAR 15, 2017 9:00 AM PDT
MAR 15, 2017 9:00 AM PDTThe idea of schizophrenia typically conjures up images of people who hear voices, see visions and have delusional beliefs. However, clinicians have long recognized cognitive dysfunction as on...Speaker: Stan Floresco, PhDPresented at: Neuroscience 2017MAR 15, 2017 7:30 AM PDT
MAR 15, 2017 7:30 AM PDTParkinson’s disease (PD) is characterized by the loss of dopamine and the disruption of brain circuits (basal ganglia and cortex) that are responsible for normal cognitive and motor per...Speaker: Giselle Petzinger, MDPresented at: Neuroscience 2017MAR 15, 2017 7:30 AM PDT
MAR 15, 2017 7:30 AM PDTOur decisions are governed by a balance between prospective instrumental goal-oriented and retrospective habitual learning strategies. This arbitration is relevant dimensionally across psychi...Speaker: Valerie Voon, MD, PhDPresented at: Neuroscience 2017NOV 17, 2016 7:00 AM PST
NOV 17, 2016 7:00 AM PSTDATE: November 17, 2016 TIME: 7:00am PT, 10:00am ET Induced pluripotent stem (iPS) cell reprogramming allows turning an adult somatic cell into a pluripotent stem cell. Four Fac...AUG 30, 2016 8:00 AM PDT
AUG 30, 2016 8:00 AM PDTA major challenge for the clinical application of pluripotent stem cell therapy for neurodegenerative diseases is large-scale manufacturing and cryopreservation of neurons and glia that can b...Speaker: Dustin Wakeman, PhDPresented at: 4th Annual 24 Hours of Stem Cells™ virtual eventAUG 30, 2016 8:00 AM PDT
AUG 30, 2016 8:00 AM PDTMost discussions about pluripotent stem cells center around their promise for regenerative medicine. The most remarkable quality of these cells is their ability to turn into all of the ...Speaker: Jeanne LoringPresented at: 4th Annual 24 Hours of Stem Cells™ virtual eventMAR 17, 2016 12:00 PM PDT
MAR 17, 2016 12:00 PM PDTSchizophrenia, depression, bipolar disorder are all uniquely human conditions. Psychiatric conditions include alterations in several different and overlapping domains (NIMH RDoC). Each...Speaker: Patricio O'Donnell, PhDPresented at: NeuroscienceMAR 17, 2016 6:00 AM PDT
MAR 17, 2016 6:00 AM PDTIn this presentation, Arvid Carlsson, who was awarded the Nobel prize in 2000 for his discovery of the transmitter role of dopamine, will be interviewed by Elias Eriksson. The following aspec...Speaker: Arvid Carlsson, MD, PhDPresented at: NeuroscienceMAR 16, 2016 1:30 PM PDT
MAR 16, 2016 1:30 PM PDTImpulse control disorders (ICDs), also known as behavioural addictions, are common in the general population and can have marked consequences. ICDs can also commonly occur with exposure...Speaker: Valerie Voon, MD, PhDPresented at: NeuroscienceMAR 16, 2016 12:00 PM PDT
MAR 16, 2016 12:00 PM PDTTraditional models of basal ganglia disorders are grounded in the assumption that network dysfunction is driven by alterations in intrinsic excitability of striatal neurons. Recent work has c...Speaker: D James Surmeier, PhDPresented at: NeuroscienceMAR 16, 2016 9:00 AM PDT
MAR 16, 2016 9:00 AM PDTWe routinely face decisions requiring evaluation and choice of different actions may or may not yield different types of rewards. These situations trigger competitive decision biases that ref...Speaker: Stan Floresco, PhDPresented at: NeuroscienceDEC 08, 2015 8:00 AM PST
DEC 08, 2015 8:00 AM PSTDecember 8th, 2015 8:00 am PT, 10:00 am CT Cryopreservation of post-mitotic, induced pluripotent stem cell-derived midbrain lineage dopamine neurons (iPSC-mDA) is a significant advan...Speaker: Dustin Wakeman, PhDSponsored By: Cellular Dynamics, Cellular DynamicsMAR 19, 2015 10:30 AM PDT
MAR 19, 2015 10:30 AM PDTSince the discovery and maturing of in vitro techniques that characterized neurotransmitter receptor systems in animal and human brain and subsequent development of in vitro and in vivo autor...Speaker: Dean Wong, MD, PhDPresented at: NeuroscienceMAR 19, 2015 7:30 AM PDT
MAR 19, 2015 7:30 AM PDTTraditional psychiatric textbooks describe schizophrenia as a clinical enigma of unknown aetiology. However, this is no longer true. We now know a great deal about the risk factors, or contr...Speaker: Sir Robin Murray, PhDPresented at: NeuroscienceMAR 19, 2015 6:00 AM PDT
MAR 19, 2015 6:00 AM PDTThis presentation will include both preclinical and small clinical studies with details on mechanism of action, safety and efficacy of a candidate drug that has the capability of alleviating...Speaker: Arvid Carlsson, MD, PhDPresented at: NeuroscienceMAR 18, 2015 6:00 AM PDT
MAR 18, 2015 6:00 AM PDTThe dopamine-containing neurons of the midbrain have been implicated in a broad array of psychiatric disorders, ranging from schizophrenia to drug abuse and depression. However, studies seem...Speaker: Anthony Grace, PhDPresented at: NeuroscienceMAR 19, 2014 11:00 AM PDT
MAR 19, 2014 11:00 AM PDT...Speaker: Anthony Grace, PhDPresented at: Neuroscience
MAR 11, 2020
3:00 PM PDT
C.E. CREDITS
MAR 11, 2020
3:00 PM PDT
Working memory (the ability to hold some information in mind for a few seconds, and to manipulate that information) and decision-making (committing to one out of multiple possible choices) a...
Speaker:
Carlos Brody, PhD
,
Ben Engelhard, PhD
,
Stephen Keeley, PhD
,
Marlies Oostland, PhD
,
Lucas Pinto, MD, PhD
,
Adrian Wanner, PhD
,
Ilana Witten, PhD
Presented at: Neuroscience 2020
MAR 11, 2020
1:30 PM PDT
C.E. CREDITS
MAR 11, 2020
1:30 PM PDT
Learning is often an emotional process. Emotional stimuli with different valences, such as threat and reward, can transform an otherwise neutral sensory input into one that can trigger disti...
Speaker:
Bo Li
,
Tianyi Mao
,
Haining Zhong
Presented at: Neuroscience 2020
MAR 11, 2020
6:00 AM PDT
C.E. CREDITS
MAR 11, 2020
6:00 AM PDT
We present here a framework to generate a realistic multiscale circuit model of the larval zebrafish brain – the multiscale virtual fish (MVF). The model will be based on algorithms in...
Speaker:
Florian Engert, PhD
,
Jeff Lichtman, MD, PhD
,
Haim Sompolinsky
Presented at: Neuroscience 2020
C.E. CREDITS
The dopamine D4 receptor (D4R) is enriched in the prefrontal cortex where it plays important roles in cognition, attention, decision making and executive function. Novel D4R-selective ligand...
Speaker:
Comfort Boateng, PhD
Presented at: Neuroscience 2020
C.E. CREDITS
Striatal neuromodulation through G-protein-coupled receptors (GPCRs) regulates complex voluntary motor actions, involving decision-making, learning, and action selection. The dorsal striatum...
Speaker:
Shana Augustin, PhD
Presented at: Neuroscience 2020
FEB 27, 2019
8:00 AM PST
C.E. CREDITS
FEB 27, 2019
8:00 AM PST
DATE: February 27, 2019TIME: 8:00am PST Pluripotent stem cells (PSCs) can form any tissue or cell in the body, and are the ideal starting material to manufacture...
Speaker:
Benjamin Fryer
Sponsored By: Thermo Fisher Scientific/Gibco
DEC 06, 2018
9:00 AM PST
DEC 06, 2018
9:00 AM PST
DATE: December 6, 2018TIME: 9:00am PST, 12:00pm EST Induced pluripotent stem cells (iPSC) intended for translational applications need to be of...
Speaker:
Tia Hexom, PhD
Sponsored By: Thermo Fisher Scientific/Gibco
MAR 15, 2017
9:00 AM PDT
MAR 15, 2017
9:00 AM PDT
The idea of schizophrenia typically conjures up images of people who hear voices, see visions and have delusional beliefs. However, clinicians have long recognized cognitive dysfunction as on...
Speaker:
Stan Floresco, PhD
Presented at: Neuroscience 2017
MAR 15, 2017
7:30 AM PDT
MAR 15, 2017
7:30 AM PDT
Parkinson’s disease (PD) is characterized by the loss of dopamine and the disruption of brain circuits (basal ganglia and cortex) that are responsible for normal cognitive and motor per...
Speaker:
Giselle Petzinger, MD
Presented at: Neuroscience 2017
MAR 15, 2017
7:30 AM PDT
MAR 15, 2017
7:30 AM PDT
Our decisions are governed by a balance between prospective instrumental goal-oriented and retrospective habitual learning strategies. This arbitration is relevant dimensionally across psychi...
Speaker:
Valerie Voon, MD, PhD
Presented at: Neuroscience 2017
NOV 17, 2016
7:00 AM PST
NOV 17, 2016
7:00 AM PST
DATE: November 17, 2016
TIME: 7:00am PT, 10:00am ET
Induced pluripotent stem (iPS) cell reprogramming allows turning an adult somatic cell into a pluripotent stem cell. Four Fac...
AUG 30, 2016
8:00 AM PDT
AUG 30, 2016
8:00 AM PDT
A major challenge for the clinical application of pluripotent stem cell therapy for neurodegenerative diseases is large-scale manufacturing and cryopreservation of neurons and glia that can b...
Speaker:
Dustin Wakeman, PhD
Presented at: 4th Annual 24 Hours of Stem Cells™ virtual event
AUG 30, 2016
8:00 AM PDT
AUG 30, 2016
8:00 AM PDT
Most discussions about pluripotent stem cells center around their promise for regenerative medicine. The most remarkable quality of these cells is their ability to turn into all of the ...
Speaker:
Jeanne Loring
Presented at: 4th Annual 24 Hours of Stem Cells™ virtual event
MAR 17, 2016
12:00 PM PDT
MAR 17, 2016
12:00 PM PDT
Schizophrenia, depression, bipolar disorder are all uniquely human conditions. Psychiatric conditions include alterations in several different and overlapping domains (NIMH RDoC). Each...
Speaker:
Patricio O'Donnell, PhD
Presented at: Neuroscience
MAR 17, 2016
6:00 AM PDT
MAR 17, 2016
6:00 AM PDT
In this presentation, Arvid Carlsson, who was awarded the Nobel prize in 2000 for his discovery of the transmitter role of dopamine, will be interviewed by Elias Eriksson. The following aspec...
Speaker:
Arvid Carlsson, MD, PhD
Presented at: Neuroscience
MAR 16, 2016
1:30 PM PDT
MAR 16, 2016
1:30 PM PDT
Impulse control disorders (ICDs), also known as behavioural addictions, are common in the general population and can have marked consequences. ICDs can also commonly occur with exposure...
Speaker:
Valerie Voon, MD, PhD
Presented at: Neuroscience
MAR 16, 2016
12:00 PM PDT
MAR 16, 2016
12:00 PM PDT
Traditional models of basal ganglia disorders are grounded in the assumption that network dysfunction is driven by alterations in intrinsic excitability of striatal neurons. Recent work has c...
Speaker:
D James Surmeier, PhD
Presented at: Neuroscience
MAR 16, 2016
9:00 AM PDT
MAR 16, 2016
9:00 AM PDT
We routinely face decisions requiring evaluation and choice of different actions may or may not yield different types of rewards. These situations trigger competitive decision biases that ref...
Speaker:
Stan Floresco, PhD
Presented at: Neuroscience
DEC 08, 2015
8:00 AM PST
DEC 08, 2015
8:00 AM PST
December 8th, 2015 8:00 am PT, 10:00 am CT
Cryopreservation of post-mitotic, induced pluripotent stem cell-derived midbrain lineage dopamine neurons (iPSC-mDA) is a significant advan...
Speaker:
Dustin Wakeman, PhD
Sponsored By: Cellular Dynamics,
Cellular Dynamics
MAR 19, 2015
10:30 AM PDT
MAR 19, 2015
10:30 AM PDT
Since the discovery and maturing of in vitro techniques that characterized neurotransmitter receptor systems in animal and human brain and subsequent development of in vitro and in vivo autor...
Speaker:
Dean Wong, MD, PhD
Presented at: Neuroscience
MAR 19, 2015
7:30 AM PDT
MAR 19, 2015
7:30 AM PDT
Traditional psychiatric textbooks describe schizophrenia as a clinical enigma of unknown aetiology. However, this is no longer true. We now know a great deal about the risk factors, or contr...
Speaker:
Sir Robin Murray, PhD
Presented at: Neuroscience
MAR 19, 2015
6:00 AM PDT
MAR 19, 2015
6:00 AM PDT
This presentation will include both preclinical and small clinical studies with details on mechanism of action, safety and efficacy of a candidate drug that has the capability of alleviating...
Speaker:
Arvid Carlsson, MD, PhD
Presented at: Neuroscience
MAR 18, 2015
6:00 AM PDT
MAR 18, 2015
6:00 AM PDT
The dopamine-containing neurons of the midbrain have been implicated in a broad array of psychiatric disorders, ranging from schizophrenia to drug abuse and depression. However, studies seem...
Speaker:
Anthony Grace, PhD
Presented at: Neuroscience
MAR 19, 2014
11:00 AM PDT
MAR 19, 2014
11:00 AM PDT
...
Speaker:
Anthony Grace, PhD
Presented at: Neuroscience
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