Dopamine
Dopamine is a neurotransmitter, one of those chemicals that is responsible for transmitting signals in between the nerve cells (neurons) of the brain. Very few neurons actually make dopamine. Some, in a part of the brain called the substantia nigra, are the cells that die during Parkinsons disease. The functions of others, located in a part of the brain called the ventral tegmental area (VTA), are less well defined and are the major source of the aforementioned controversy (and the focus of this post). When dopamine neurons become activated, they release dopamine.
MAR 11, 2020
1:30 PM PDT
C.E. CREDITS
MAR 11, 2020
1:30 PM PDT
Learning is often an emotional process. Emotional stimuli with different valences, such as threat and reward, can transform an otherwise neutral sensory input into one that can trigger disti...
MAR 11, 2020
6:00 AM PDT
C.E. CREDITS
MAR 11, 2020
6:00 AM PDT
We present here a framework to generate a realistic multiscale circuit model of the larval zebrafish brain – the multiscale virtual fish (MVF). The model will be based on algorithms in...
C.E. CREDITS
The dopamine D4 receptor (D4R) is enriched in the prefrontal cortex where it plays important roles in cognition, attention, decision making and executive function. Novel D4R-selective ligand...
C.E. CREDITS
Striatal neuromodulation through G-protein-coupled receptors (GPCRs) regulates complex voluntary motor actions, involving decision-making, learning, and action selection. The dorsal striatum...
FEB 27, 2019
8:00 AM PST
FEB 27, 2019
8:00 AM PST
DATE: February 27, 2019TIME: 8:00am PST Pluripotent stem cells (PSCs) can form any tissue or cell in the body, and are the ideal starting material to manufacture...
DEC 06, 2018
9:00 AM PST
DEC 06, 2018
9:00 AM PST
DATE: December 6, 2018TIME: 9:00am PST, 12:00pm EST Induced pluripotent stem cells (iPSC) intended for translational applications need to be of...
MAR 15, 2017
9:00 AM PDT
MAR 15, 2017
9:00 AM PDT
The idea of schizophrenia typically conjures up images of people who hear voices, see visions and have delusional beliefs. However, clinicians have long recognized cognitive dysfunction as on...
MAR 15, 2017
7:30 AM PDT
MAR 15, 2017
7:30 AM PDT
Parkinson’s disease (PD) is characterized by the loss of dopamine and the disruption of brain circuits (basal ganglia and cortex) that are responsible for normal cognitive and motor per...
MAR 15, 2017
7:30 AM PDT
MAR 15, 2017
7:30 AM PDT
Our decisions are governed by a balance between prospective instrumental goal-oriented and retrospective habitual learning strategies. This arbitration is relevant dimensionally across psychi...
