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    Drug Design

    Drug Design: often referred to as rational drug design or simply rational design, is the inventive process of finding new medications based on the knowledge of a biological target.

    Webinars

    • NOV 17, 2015 | 8:00 AM
      Unleashing the power of biobanks to drive translational science forward
      Unleashing the power of biobanks to drive translational science...
      DATE: November 17th, 2015TIME: 8am PDT, 11am EDT, 4pm GMTBiobanks provide important capacity to collect large genomic data sets intended to enable the study of genetic signatures of an...
      Speaker: Conny Mathay , Andrew Brooks, Ph.D. , Jens Hoefkens, PhD
      Sponsored By: Revvity
      22
      OCT 27, 2015 | 8:00 AM
      Multidimensional High-Throughput Imaging with the New ImageXpress Micro Confocal System
      Multidimensional High-Throughput Imaging with the New ImageXpress...
      Date: October 27th, 2015 TIME: 8am PDT, 11am EDT, 3pm GMT, 11pm Beijing In recent years there have been great advances in automated microscopy and imaging for generating more predictive, ...
      Speaker: Jayne Hesley , Grischa Chandy, PhD
      Sponsored By: Molecular Devices, Molecular Devices
      22
      OCT 01, 2015 | 8:00 AM
      WEBINAR: Close your uncertainty gap with High Resolution Mass Spectrometry
      WEBINAR: Close your uncertainty gap with High Resolution Mass...
      Is your lab constantly challenged by case back log while trying to validate new methods to identify designer drugs? Your challenge is common to many forensic toxicology labs around the world....
      Speaker: Maciej Bromirski, MSc , Kristine Van Natta
      Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
      2 1
      SEP 22, 2015 | 8:00 AM
      WEBINAR: SPR for Aptamer-Based Molecular Interactions in Programmable Materials
      WEBINAR: SPR for Aptamer-Based Molecular Interactions in Programmable...
      Surface plasmon resonance (SPR) is a sensitive, label-free technique that detects mass changes due to biomolecular interactions on a surface. This versatile method has been used to evaluate t...
      Speaker: Erin Gaddes, MS
      Sponsored By: Ametek, Ametek
      5
      SEP 16, 2015 | 2:00 PM
      Enabling the Best Structure-Based Design Engine:a Human Expert
      Enabling the Best Structure-Based Design Engine:a Human Expert
      Structure-based drug discovery requires expert designers, aided by software that integrates 3D structure visualization and molecular editing with multivariate experimentaland calculated prope...
      Speaker: Jeff Blaney
      Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
      3
      SEP 16, 2015 | 12:00 PM
      Developing Accurate Nanomedicines: The BIND Therapeutics Approach
      Developing Accurate Nanomedicines: The BIND Therapeutics Approach
      Nanotechnology, the engineering and manufacture of materials at the atomic and molecular scale, is used at BIND Therapeutics to develop novel Accurinâ„¢ nanomedicines that utilize cytotoxic age...
      Speaker: Hagop Youssoufian
      Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
      2
      SEP 16, 2015 | 6:00 AM
      Of soft drinks and software: a framework to sustain innovation in computational molecular design
      Of soft drinks and software: a framework to sustain innovation...
      One of the challenges in sustaining innovation in computational molecular design is the need to harness and deliver promising solutions irrespective of their source, without creating new soft...
      Speaker: Enoch Huang
      Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
      2
      SEP 03, 2015 | 1:30 PM
      Challenges of Natural Preservative Application
      Challenges of Natural Preservative Application
      Natural preservation is often cited as effective and “safe” alternative to traditional synthetic preservative systems. However, the so-called natural preservatives bring a number...
      Speaker: Philip Geis, PhD
      Presented at: Microbiology Virtual Event Series 2015
      2 1
      SEP 02, 2015 | 1:30 PM
      How Anthropogenic Chemicals are Altering the Microbial World
      How Anthropogenic Chemicals are Altering the Microbial World
      The world–as microbes perceive it–is composed of physical and chemical stimuli. These stimuli create conditions that result in life or death for microbes, affecting their survival...
      Speaker: Erica Hartmann, PhD
      Presented at: Microbiology Virtual Event Series 2015
      3
      MAY 26, 2015 | 9:00 AM
      Intelligent NGS Assay Design: Oncomineâ„¢ Focus Assay for NGS clinical research in oncology
      Intelligent NGS Assay Design: Oncomineâ„¢ Focus Assay for NGS clinical...
      DATE: Tuesday, May 26th, 2015TIME: 09:00AM PDT, 12:00PM EDTNext-generation sequencing (NGS) is changing the landscape of clinical research. This powerful technology is enabling researchers to...
      Speaker: Seth Sadis
      Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
      7
      MAY 13, 2015 | 6:00 AM
      Predictive Gene Signatures: Molecular Markers Distinguishing Colon Adenomatous Polyp and Carcinoma
      Predictive Gene Signatures: Molecular Markers Distinguishing Colon...
      Cancers exhibit abnormal molecular signatures associated with disease initiation and progression. Molecular signatures could improve cancer screening, detection, drug development and selectio...
      Speaker: Janice Drew, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      0
      FEB 05, 2015 | 3:00 PM
      C.E. CREDITS
      Aquaculture and Biomedical Research of Non-traditional Aquatics
      Aquaculture and Biomedical Research of Non-traditional Aquatics
      As evidenced by the changes in the new Guide for the Care and Use of Laboratory animals and the latest AVMA Panel on Euthanasia, it is clear that there is growing concern about the care and w...
      Speaker: Dan Rothen, DVM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      7
      FEB 05, 2015 | 12:00 PM
      C.E. CREDITS
      The importance of pre-operative assessment and post-operative care in surgical procedures
      The importance of pre-operative assessment and post-operative...
      The pre-operative assessment and post-operative is critical for successful surgical procedures which will in turn lead to high quality outcomes in research studies. The care of the animals go...
      Speaker: Pilar Ariza Guzman, DVM, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      6
      FEB 05, 2015 | 10:30 AM
      C.E. CREDITS
      Importance/effect of surgical training, skills and experience on performing surgical procedures within studies
      Importance/effect of surgical training, skills and experience...
      In the context of an experimental project requiring surgical preparation of animals, training is not only required for technicians lacking a strong surgical background but also for more exper...
      Speaker: Delphine Bouard DVM, Dip Vet LAS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      13
      FEB 05, 2015 | 7:30 AM
      C.E. CREDITS
      Small Animal Anesthesia: A New Method to Help Control Variables
      Small Animal Anesthesia: A New Method to Help Control Variables
      An anesthesia system designed to accommodate the physiological characteristics of small animals, including rats and mice, has the potential to provide great practical value to the life scienc...
      Speaker: Andrew H Ide, BS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      12
      FEB 04, 2015 | 10:30 AM
      C.E. CREDITS
      Keynote: Practical Tips to Optimize Surgical Results in Rodents
      Keynote: Practical Tips to Optimize Surgical Results in Rodents
      It is the often-ignored simple tips in rodent surgery that make the difference and help minimize postoperative complications and mortality. The presenter will use his years of experience to...
      Speaker: Marcel Perret-Gentil, DVM, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      4
      FEB 04, 2015 | 9:00 AM
      C.E. CREDITS
      Keynote: Applying Principles of Biosafety in Laboratory Animal Facilities
      Keynote: Applying Principles of Biosafety in Laboratory Animal...
      Some commonly accepted principles of biosafety include the strict adherence to standard laboratory practices and techniques, the use of safety equipment such as primary barriers and personal...
      Speaker: James R Swearengen, DVM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      14
      FEB 04, 2015 | 7:30 AM
      C.E. CREDITS
      Normal behavior of rodents: understand it, then respect it
      Normal behavior of rodents: understand it, then respect it
      During my presentation, we will discuss:- Normal patterns of behavior (repertoire): social, food intake, territorial, agonistic, anti-predation, sleep and rest, play behavior, grooming, sex...
      Speaker: Marina Snitcofsky, DVM, MSc, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      7
      FEB 04, 2015 | 6:00 AM
      C.E. CREDITS
      Training, Competency Assessment and Best Practice in Aseptic Technique
      Training, Competency Assessment and Best Practice in Aseptic Technique
      Adherence to strict aseptic technique is vital to all types of animal models requiring surgical intervention from both scientific and welfare perspectives. Training of both new and experience...
      Speaker: Angela Kerton, B.VetMed Cert LAS MRCVS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      7
      NOV 12, 2014 | 8:00 AM
      Hallmarks of cancer - Detect and quantify cell death signatures with high content imaging
      Hallmarks of cancer - Detect and quantify cell death signatures...
      Dr. Oliver Kepp will be presenting on:Immunogenic cell death fingerprinting utilizing a high-throughput screening approachThe strategy of immunogenic cell death fingerprinting has been design...
      Speaker: Oliver Kepp, PhD and Jayne A. Hesley
      Sponsored By: Molecular Devices, Molecular Devices
      33
      OCT 30, 2014 | 3:00 PM
      Clinical Shotgun Proteomics in Cancer Biomarker and Drug Target Research/Discovery
      Clinical Shotgun Proteomics in Cancer Biomarker and Drug Target...
      Mass spectrometry (MS)-based profiling of clinical specimens has been increasingly used in cancer research to characterize changes in protein expression between tumor and healthy tissue or be...
      Speaker: Josip Blonder, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      30
      OCT 30, 2014 | 1:30 PM
      Dissecting cancer signaling pathways with chemical scalpels
      Dissecting cancer signaling pathways with chemical scalpels
      Advances in genomic research have led to identification of the majority of the drivers of tumor progression. However, our understanding of the molecular mechanisms propelling tumor growth is...
      Speaker: Nadya Tarasova, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      14
      OCT 29, 2014 | 3:00 PM
      Drug-tailored, efficacy-predictive and prognostic biomarker approaches for proper patient selection
      Drug-tailored, efficacy-predictive and prognostic biomarker approaches...
      Over the last decade we have witnessed tremendous advances in our understanding of the underlying molecular alterations in human cancer. This has stimulated excitement for our ability to deve...
      Speaker: Peter Blume-Jensen, MD, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      0
      OCT 29, 2014 | 3:00 PM
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
      Speaker: Michael J Mann, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      67
    NOV 17, 2015 | 8:00 AM
    Unleashing the power of biobanks to drive translational science forward
    Unleashing the power of biobanks to drive translational science...
    DATE: November 17th, 2015TIME: 8am PDT, 11am EDT, 4pm GMTBiobanks provide important capacity to collect large genomic data sets intended to enable the study of genetic signatures of an...
    Speaker: Conny Mathay , Andrew Brooks, Ph.D. , Jens Hoefkens, PhD
    Sponsored By: Revvity
    22
    OCT 27, 2015 | 8:00 AM
    Multidimensional High-Throughput Imaging with the New ImageXpress Micro Confocal System
    Multidimensional High-Throughput Imaging with the New ImageXpress...
    Date: October 27th, 2015 TIME: 8am PDT, 11am EDT, 3pm GMT, 11pm Beijing In recent years there have been great advances in automated microscopy and imaging for generating more predictive, ...
    Speaker: Jayne Hesley , Grischa Chandy, PhD
    Sponsored By: Molecular Devices, Molecular Devices
    22
    OCT 01, 2015 | 8:00 AM
    WEBINAR: Close your uncertainty gap with High Resolution Mass Spectrometry
    WEBINAR: Close your uncertainty gap with High Resolution Mass...
    Is your lab constantly challenged by case back log while trying to validate new methods to identify designer drugs? Your challenge is common to many forensic toxicology labs around the world....
    Speaker: Maciej Bromirski, MSc , Kristine Van Natta
    Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
    2 1
    SEP 22, 2015 | 8:00 AM
    WEBINAR: SPR for Aptamer-Based Molecular Interactions in Programmable Materials
    WEBINAR: SPR for Aptamer-Based Molecular Interactions in Programmable...
    Surface plasmon resonance (SPR) is a sensitive, label-free technique that detects mass changes due to biomolecular interactions on a surface. This versatile method has been used to evaluate t...
    Speaker: Erin Gaddes, MS
    Sponsored By: Ametek, Ametek
    5
    SEP 16, 2015 | 2:00 PM
    Enabling the Best Structure-Based Design Engine:a Human Expert
    Enabling the Best Structure-Based Design Engine:a Human Expert
    Structure-based drug discovery requires expert designers, aided by software that integrates 3D structure visualization and molecular editing with multivariate experimentaland calculated prope...
    Speaker: Jeff Blaney
    Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
    3
     
     
  • SEP 16, 2015 | 12:00 PM
    Developing Accurate Nanomedicines: The BIND Therapeutics Approach
    Developing Accurate Nanomedicines: The BIND Therapeutics Approach
    Nanotechnology, the engineering and manufacture of materials at the atomic and molecular scale, is used at BIND Therapeutics to develop novel Accurinâ„¢ nanomedicines that utilize cytotoxic age...
    Speaker: Hagop Youssoufian
    Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
    2
    SEP 16, 2015 | 6:00 AM
    Of soft drinks and software: a framework to sustain innovation in computational molecular design
    Of soft drinks and software: a framework to sustain innovation...
    One of the challenges in sustaining innovation in computational molecular design is the need to harness and deliver promising solutions irrespective of their source, without creating new soft...
    Speaker: Enoch Huang
    Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
    2
    SEP 03, 2015 | 1:30 PM
    Challenges of Natural Preservative Application
    Challenges of Natural Preservative Application
    Natural preservation is often cited as effective and “safe” alternative to traditional synthetic preservative systems. However, the so-called natural preservatives bring a number...
    Speaker: Philip Geis, PhD
    Presented at: Microbiology Virtual Event Series 2015
    2 1
    SEP 02, 2015 | 1:30 PM
    How Anthropogenic Chemicals are Altering the Microbial World
    How Anthropogenic Chemicals are Altering the Microbial World
    The world–as microbes perceive it–is composed of physical and chemical stimuli. These stimuli create conditions that result in life or death for microbes, affecting their survival...
    Speaker: Erica Hartmann, PhD
    Presented at: Microbiology Virtual Event Series 2015
    3
    MAY 26, 2015 | 9:00 AM
    Intelligent NGS Assay Design: Oncomineâ„¢ Focus Assay for NGS clinical research in oncology
    Intelligent NGS Assay Design: Oncomineâ„¢ Focus Assay for NGS clinical...
    DATE: Tuesday, May 26th, 2015TIME: 09:00AM PDT, 12:00PM EDTNext-generation sequencing (NGS) is changing the landscape of clinical research. This powerful technology is enabling researchers to...
    Speaker: Seth Sadis
    Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
    7
     
     
  • MAY 13, 2015 | 6:00 AM
    Predictive Gene Signatures: Molecular Markers Distinguishing Colon Adenomatous Polyp and Carcinoma
    Predictive Gene Signatures: Molecular Markers Distinguishing Colon...
    Cancers exhibit abnormal molecular signatures associated with disease initiation and progression. Molecular signatures could improve cancer screening, detection, drug development and selectio...
    Speaker: Janice Drew, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    0
    FEB 05, 2015 | 3:00 PM
    C.E. CREDITS
    Aquaculture and Biomedical Research of Non-traditional Aquatics
    Aquaculture and Biomedical Research of Non-traditional Aquatics
    As evidenced by the changes in the new Guide for the Care and Use of Laboratory animals and the latest AVMA Panel on Euthanasia, it is clear that there is growing concern about the care and w...
    Speaker: Dan Rothen, DVM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    7
    FEB 05, 2015 | 12:00 PM
    C.E. CREDITS
    The importance of pre-operative assessment and post-operative care in surgical procedures
    The importance of pre-operative assessment and post-operative...
    The pre-operative assessment and post-operative is critical for successful surgical procedures which will in turn lead to high quality outcomes in research studies. The care of the animals go...
    Speaker: Pilar Ariza Guzman, DVM, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    6
    FEB 05, 2015 | 10:30 AM
    C.E. CREDITS
    Importance/effect of surgical training, skills and experience on performing surgical procedures within studies
    Importance/effect of surgical training, skills and experience...
    In the context of an experimental project requiring surgical preparation of animals, training is not only required for technicians lacking a strong surgical background but also for more exper...
    Speaker: Delphine Bouard DVM, Dip Vet LAS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    13
    FEB 05, 2015 | 7:30 AM
    C.E. CREDITS
    Small Animal Anesthesia: A New Method to Help Control Variables
    Small Animal Anesthesia: A New Method to Help Control Variables
    An anesthesia system designed to accommodate the physiological characteristics of small animals, including rats and mice, has the potential to provide great practical value to the life scienc...
    Speaker: Andrew H Ide, BS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    12
     
     
  • FEB 04, 2015 | 10:30 AM
    C.E. CREDITS
    Keynote: Practical Tips to Optimize Surgical Results in Rodents
    Keynote: Practical Tips to Optimize Surgical Results in Rodents
    It is the often-ignored simple tips in rodent surgery that make the difference and help minimize postoperative complications and mortality. The presenter will use his years of experience to...
    Speaker: Marcel Perret-Gentil, DVM, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    4
    FEB 04, 2015 | 9:00 AM
    C.E. CREDITS
    Keynote: Applying Principles of Biosafety in Laboratory Animal Facilities
    Keynote: Applying Principles of Biosafety in Laboratory Animal...
    Some commonly accepted principles of biosafety include the strict adherence to standard laboratory practices and techniques, the use of safety equipment such as primary barriers and personal...
    Speaker: James R Swearengen, DVM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    14
    FEB 04, 2015 | 7:30 AM
    C.E. CREDITS
    Normal behavior of rodents: understand it, then respect it
    Normal behavior of rodents: understand it, then respect it
    During my presentation, we will discuss:- Normal patterns of behavior (repertoire): social, food intake, territorial, agonistic, anti-predation, sleep and rest, play behavior, grooming, sex...
    Speaker: Marina Snitcofsky, DVM, MSc, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    7
    FEB 04, 2015 | 6:00 AM
    C.E. CREDITS
    Training, Competency Assessment and Best Practice in Aseptic Technique
    Training, Competency Assessment and Best Practice in Aseptic Technique
    Adherence to strict aseptic technique is vital to all types of animal models requiring surgical intervention from both scientific and welfare perspectives. Training of both new and experience...
    Speaker: Angela Kerton, B.VetMed Cert LAS MRCVS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    7
    NOV 12, 2014 | 8:00 AM
    Hallmarks of cancer - Detect and quantify cell death signatures with high content imaging
    Hallmarks of cancer - Detect and quantify cell death signatures...
    Dr. Oliver Kepp will be presenting on:Immunogenic cell death fingerprinting utilizing a high-throughput screening approachThe strategy of immunogenic cell death fingerprinting has been design...
    Speaker: Oliver Kepp, PhD and Jayne A. Hesley
    Sponsored By: Molecular Devices, Molecular Devices
    33
     
     
  • OCT 30, 2014 | 3:00 PM
    Clinical Shotgun Proteomics in Cancer Biomarker and Drug Target Research/Discovery
    Clinical Shotgun Proteomics in Cancer Biomarker and Drug Target...
    Mass spectrometry (MS)-based profiling of clinical specimens has been increasingly used in cancer research to characterize changes in protein expression between tumor and healthy tissue or be...
    Speaker: Josip Blonder, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    30
    OCT 30, 2014 | 1:30 PM
    Dissecting cancer signaling pathways with chemical scalpels
    Dissecting cancer signaling pathways with chemical scalpels
    Advances in genomic research have led to identification of the majority of the drivers of tumor progression. However, our understanding of the molecular mechanisms propelling tumor growth is...
    Speaker: Nadya Tarasova, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    14
    OCT 29, 2014 | 3:00 PM
    Drug-tailored, efficacy-predictive and prognostic biomarker approaches for proper patient selection
    Drug-tailored, efficacy-predictive and prognostic biomarker approaches...
    Over the last decade we have witnessed tremendous advances in our understanding of the underlying molecular alterations in human cancer. This has stimulated excitement for our ability to deve...
    Speaker: Peter Blume-Jensen, MD, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    0
    OCT 29, 2014 | 3:00 PM
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
    Speaker: Michael J Mann, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
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