Health: as defined by the World Health Organization (WHO), is "a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity." This definition has been subject to controversy, as it may have limited value for implementation. Health may be defined as the ability to adapt and manage physical, mental and social challenges throughout life.
DATE: June 14, 2017TIME: 6:00am PT, 9:00am ET, 3:00pm CETComprehensive metabolite profiling (i.e., metabolomics) offers a holistic approach for understanding the phenotype of an organis...
The nature of work in the clinical core lab has changed over the years from beakers of liquids, specimens and compounds on countertops to sophisticated equipment with prepackaged reagents and...
Those that fund and publish scientific data are actively proposing or requiring strategies to improve research conduct in the hopes of improving research outcomes and scientific deliverables....
DATE: May 22, 2017TIME: 10:00am PT, 1:00pm ETLearn from renowned clinical expert, George J. Alangaden, M.D., as he discusses how Henry Ford Health System (HFHS) implemented T2MR and the...
DATE: May 22, 2017TIME: 8:00AM PDT, 11:00AM ETCrohn's disease (CD) results from a complex interplay between host genetic factors and endogenous microbial communities. In the current...
DATE: May 17, 2017TIME: 10:30am PT, 1:30pm ETNeurons derived from human pluripotent stem cells (hPSCs) and primary rodent neurons both are excellent resources for disease modeling and d...
Much has been said about the promise of Next Generation Sequencing (NGS) to revolutionise diagnosis of rare diseases, and there are many examples of success in this arena. However, the majori...
The study of inherited genomic variation through genome wide association studies (GWAS) promised to provide key biologic insight into common diseases of public health significance such as obe...
Genetic testing currently plays a relatively niche role in healthcare, with testing typically limited to single genes and targeting a relatively narrow range of diseases, including paediatric...
Boston Children’s Hospital is developing the infrastructure needed for large-scale psychiatric research and treatment discovery. The Manton Center for Orphan Disease Research and...
Characterizing cellular hierarchy has profound implications in development and diseases. Single-cell technologies have great potential in discovering new cell types and lineage relationships,...
Although ultrahigh-throughput RNA-sequencing has become the dominant technology for genome-wide transcriptional profiling, the vast majority of RNA-seq studies typically profile only tens of...
We have developed a semi-automated, high-throughput transient expression and purification system that yields milligram quantities of hundreds of proteins weekly. Starting from a glycerol stoc...
Genome Wide Association Studies (GWAS) and expression quantitative trait locus (eQTL) analyses have identified genetic associations with a wide range of human phenotypes. However, many of the...
When studying the transcriptome, most of our inferences revolve around changes in average expression. However, more recent examples have demonstrated that analysis of the variability of gene...
DATE: May 8th, 2017TIME: 10:00AM PT, 11:00AM MT, 12:00PM CT, 1:00PM ETThis webinar will describe the potential diagnostic benefits of using the dissociated VIDAS Lyme IgM II and VIDAS L...
DATE: May 2, 2017TIME: 8:00am PT, 11:00am ET, 4:00pm GMT, 5:00pm CETThe natural immune responses that patients develop to their own tumors, as well as therapeutic regimens employin...
Neurons derived from human pluripotent stem cells (hPSCs) and primary rodent neurons both are excellent resources for disease modeling and drug screening. Human PSCs derived neural stem...
DATE: April 26, 2017TIME: 9:00AM PT, 12:00PM ETBiopsies from non-small cell lung cancer (NSCLC) and colorectal adenocarcinoma generally produce small, heterogeneous samples with li...
This presentation describes the new process by which the Centers for Medicare and Medicaid Services (CMS) will establish the prices the Agency pays for clinical diagnostic laboratory tests.&n...
Screening for cervical cancer represents one of the greatest successes achieved in disease prevention. Cytology has been central to cervical cancer screening programs for over 50 years and ha...
As next generation sequencing has lowered the price of DNA sequencing orders of magnitude below what it cost to create the first consensus human genome, the sheer diversity of human sequence...
DATE: April 11, 2017TIME: 8:00 AM PT, 11:00 AM ET Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond....
DATE: June 14, 2017TIME: 6:00am PT, 9:00am ET, 3:00pm CETComprehensive metabolite profiling (i.e., metabolomics) offers a holistic approach for understanding the phenotype of an organis...
The nature of work in the clinical core lab has changed over the years from beakers of liquids, specimens and compounds on countertops to sophisticated equipment with prepackaged reagents and...
Those that fund and publish scientific data are actively proposing or requiring strategies to improve research conduct in the hopes of improving research outcomes and scientific deliverables....
DATE: May 22, 2017TIME: 10:00am PT, 1:00pm ETLearn from renowned clinical expert, George J. Alangaden, M.D., as he discusses how Henry Ford Health System (HFHS) implemented T2MR and the...
DATE: May 22, 2017TIME: 8:00AM PDT, 11:00AM ETCrohn's disease (CD) results from a complex interplay between host genetic factors and endogenous microbial communities. In the current...
DATE: May 17, 2017TIME: 10:30am PT, 1:30pm ETNeurons derived from human pluripotent stem cells (hPSCs) and primary rodent neurons both are excellent resources for disease modeling and d...
Much has been said about the promise of Next Generation Sequencing (NGS) to revolutionise diagnosis of rare diseases, and there are many examples of success in this arena. However, the majori...
The study of inherited genomic variation through genome wide association studies (GWAS) promised to provide key biologic insight into common diseases of public health significance such as obe...
Genetic testing currently plays a relatively niche role in healthcare, with testing typically limited to single genes and targeting a relatively narrow range of diseases, including paediatric...
Boston Children’s Hospital is developing the infrastructure needed for large-scale psychiatric research and treatment discovery. The Manton Center for Orphan Disease Research and...
Characterizing cellular hierarchy has profound implications in development and diseases. Single-cell technologies have great potential in discovering new cell types and lineage relationships,...
Although ultrahigh-throughput RNA-sequencing has become the dominant technology for genome-wide transcriptional profiling, the vast majority of RNA-seq studies typically profile only tens of...
We have developed a semi-automated, high-throughput transient expression and purification system that yields milligram quantities of hundreds of proteins weekly. Starting from a glycerol stoc...
Genome Wide Association Studies (GWAS) and expression quantitative trait locus (eQTL) analyses have identified genetic associations with a wide range of human phenotypes. However, many of the...
When studying the transcriptome, most of our inferences revolve around changes in average expression. However, more recent examples have demonstrated that analysis of the variability of gene...
DATE: May 8th, 2017TIME: 10:00AM PT, 11:00AM MT, 12:00PM CT, 1:00PM ETThis webinar will describe the potential diagnostic benefits of using the dissociated VIDAS Lyme IgM II and VIDAS L...
DATE: May 2, 2017TIME: 8:00am PT, 11:00am ET, 4:00pm GMT, 5:00pm CETThe natural immune responses that patients develop to their own tumors, as well as therapeutic regimens employin...
Neurons derived from human pluripotent stem cells (hPSCs) and primary rodent neurons both are excellent resources for disease modeling and drug screening. Human PSCs derived neural stem...
DATE: April 26, 2017TIME: 9:00AM PT, 12:00PM ETBiopsies from non-small cell lung cancer (NSCLC) and colorectal adenocarcinoma generally produce small, heterogeneous samples with li...
This presentation describes the new process by which the Centers for Medicare and Medicaid Services (CMS) will establish the prices the Agency pays for clinical diagnostic laboratory tests.&n...
Screening for cervical cancer represents one of the greatest successes achieved in disease prevention. Cytology has been central to cervical cancer screening programs for over 50 years and ha...
As next generation sequencing has lowered the price of DNA sequencing orders of magnitude below what it cost to create the first consensus human genome, the sheer diversity of human sequence...
DATE: April 11, 2017TIME: 8:00 AM PT, 11:00 AM ET Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond....