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    High Throughput

    High throughput cell biology is the use of automation equipment with classical cell biology techniques to address biological questions that are otherwise unattainable using conventional methods. It may incorporate techniques from optics, chemistry, biology or image analysis to permit rapid, highly parallel research into how cells function, interact with each other and how pathogens exploit them in disease. High-throughput biology serves as one facet of what has also been called "omics research" - the interface between large scale biology (genome, proteome, transcriptome), technology and researchers. High throughput cell biology has a definite focus on the cell, and methods accessing the cell such as imaging, gene expression microarrays, or genome wide screening. The basic idea is to take methods normally performed on their own and do a very large number of them without impacting their quality.

    Webinars

    • MAY 24, 2017 | 9:00 AM
      Strand NGS Server: or, why clinical bioinformaticians love Strand
      Strand NGS Server: or, why clinical bioinformaticians love Strand
      I’ll talk about Strand NGS Server, our server-client NGS offering. Strand NGS server is geared towards small-to-medium scale clinical labs with high-volume sequencing throughputs and lo...
      Speaker: Radhakrishna Bettadapura (RK), PhD
      Presented at: Lab Automation Virtual Event Series 2017
      Sponsored By: Strand
      3
      MAY 24, 2017 | 9:00 AM
      Fully Automated 3D Cell Culture for Human Cells
      Fully Automated 3D Cell Culture for Human Cells
      The consistent and optimized production of living human cells for drug discovery and regenerative medicine faces many challenges including the need for cost effective large scale expansion, i...
      Speaker: Robin Felder, PhD
      Presented at: Lab Automation Virtual Event Series 2017
      2
      MAY 24, 2017 | 7:30 AM
      Leveraging Recent Advances in Miltenyi's Cell Sorting Automation Platforms to Reduce Time to Data in Primary Cell-Based Assays.
      Leveraging Recent Advances in Miltenyi's Cell Sorting Automation...
      This seminar will give attendees a full overview of two new Miltenyi cell sorting platforms, the MultiMACS X and the CliniMACS Prodigy and how these instruments can be used in various primary...
      Speaker: Nick Trotter-Mayo, Ph.D. MBA
      Presented at: Lab Automation Virtual Event Series 2017
      Sponsored By: Miltenyi Biotec
      2
      MAY 24, 2017 | 7:30 AM
      Case Studies: Scaling Cell Therapy Manufacturing
      Case Studies: Scaling Cell Therapy Manufacturing
      Gain insights into T-cell expansion, viral vector production and scaling production of mesenchymal stem cells (MSCs) through the use of a functionally closed, automated, cell culture process....
      Speaker: Jim Beltzer, MS, PhD
      Presented at: Lab Automation Virtual Event Series 2017
      Sponsored By: TERUMO BCT
      1
      MAY 24, 2017 | 6:00 AM
      Robots in Research
      Robots in Research
      Often we are concerned at the thought of a lab run by robots, not humans-- but what if instead of having the world's brightest minds concerned with pipetting, blotting and scanning, there...
      Speaker: Mike Simson
      Presented at: Lab Automation Virtual Event Series 2017
      Sponsored By: Bosterbio
      1
      MAY 24, 2017 | 6:00 AM
      Exploring Pharmacological Interactions with Matrix: The Innovations and Challenges of NCATS Drug Combination HTS Platform
      Exploring Pharmacological Interactions with Matrix: The Innovations...
      Acoustic dispensing technology has allowed for compound plating to be highly customizable depending upon scientific needs.  The ability to dispense compounds from a single well to any we...
      Speaker: Kelli Wilson, PhD
      Presented at: Lab Automation Virtual Event Series 2017
      3 1
      MAY 16, 2017 | 9:00 AM
      WEBINAR: Disease Models
      WEBINAR: Disease Models
      EVENT DETAILS:DATE: May 16, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science our first commit...
      Speaker: David Piper, PhD , Mark Kennedy, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      5 3
      MAY 11, 2017 | 12:00 PM
      Impact of Next-Generation Sequencing on Precision Medicine
      Impact of Next-Generation Sequencing on Precision Medicine
      It was 10 years ago that Illumina first launched the Genome Analyzer II, the world’s first high-throughput sequencing platform.  That system could produce one billion bps of sequen...
      Speaker: Gary Schroth,PhD
      Presented at: Genetics and Genomics Virtual Event Series 2017
      2
      MAY 11, 2017 | 10:30 AM
      C.E. CREDITS
      Functional Characterization of Gene Regulatory Elements
      Functional Characterization of Gene Regulatory Elements
      Nucleotide variation in gene regulatory elements is a major cause of human disease. Despite continual progress in the cataloging of these elements, little is known about the code and grammati...
      Speaker: Nadav Ahituv, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2017
      1
      MAY 10, 2017 | 2:00 PM
      Selecting the right resin to achieve optimal results, from high throughput batch to process scale protein purification
      Selecting the right resin to achieve optimal results, from high...
      The objective of academic, biotech or pharmaceutical scientists committed to protein purification is to obtain the purest protein needed for their application, regardless of scale. Towards th...
      Speaker: Aaron McBride , Scott Meier
      Presented at: 2017 Gibco ExpressionWorld
      7
      MAY 10, 2017 | 1:00 PM
      Modification of Glycans in Bioprocessing
      Modification of Glycans in Bioprocessing
      Glycosylation is an important product quality attribute for biotherapeutic proteins expressed in CHO cells. Glycoform variability can significantly affect the safety and efficacy of therapeut...
      Speaker: Ryan Boniface
      Presented at: 2017 Gibco ExpressionWorld
      4
      MAY 10, 2017 | 12:00 PM
      Ask the Expert: Mammalian Transient Expression
      Ask the Expert: Mammalian Transient Expression
      Getting started Equipment Troubleshooting Scale up or scale down your expression runs Tackling difficult-to-express proteins 293 vs. CHO cell expression...
      Speaker: Henry Chiou, PhD , Richard Altman, MS , Jon Zmuda, PhD , Konrad Miatkowski
      Presented at: 2017 Gibco ExpressionWorld
      3
      MAY 10, 2017 | 11:00 AM
      An ongoing evaluation of our transient expression systems; Can we predict the appropriate expression system for any drug modality?
      An ongoing evaluation of our transient expression systems; Can...
      CHO cells are the predominant host for biotherapeutic protein expression with approximately 70% of licensed biologics manufactured in Chinese Hamster Ovary (CHO) cells.  The ability to e...
      Speaker: Richard Altman, MS
      Presented at: 2017 Gibco ExpressionWorld
      4
      MAY 10, 2017 | 10:30 AM
      C.E. CREDITS
      Methods to account for sequencing artifacts in large high-throughput RNA-Seq data
      Methods to account for sequencing artifacts in large high-throughput...
      Although ultrahigh-throughput RNA-sequencing has become the dominant technology for genome-wide transcriptional profiling, the vast majority of RNA-seq studies typically profile only tens of...
      Speaker: Joseph Paulson, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2017
      2
      MAY 10, 2017 | 9:00 AM
      A Semi-Automated High-Throughput Transient Expression and Purification Platform using the Expi293 Expression System
      A Semi-Automated High-Throughput Transient Expression and Purification...
      We have developed a semi-automated, high-throughput transient expression and purification system that yields milligram quantities of hundreds of proteins weekly. Starting from a glycerol stoc...
      Speaker: Matthew McKenna
      Presented at: 2017 Gibco ExpressionWorld
      4
      MAY 10, 2017 | 6:00 AM
      C.E. CREDITS
      CATS - a novel library preparation method for ultrasensitive deep sequencing of extracellular circulating RNA and DNA
      CATS - a novel library preparation method for ultrasensitive deep...
      Massive parallel sequencing (MPS) technologies have paved the way into new areas of research including individualized medicine. However, sequencing of trace amounts of nucleic acids still rem...
      Speaker: Andrey Turchinovich, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2017
      Sponsored By: Diagenode
      4
      MAY 09, 2017 | 8:00 AM
      WEBINAR: Deafness in the Genomic Era: Discoveries, Challenges and Opportunities
      WEBINAR: Deafness in the Genomic Era: Discoveries, Challenges...
      DATE: May 9, 2017TIME: 8:00am PT, 11:00am ETHearing loss is the most common sensory defect in humans. It affects 360 million people worldwide and by 2020, that number is predi...
      Speaker: Hela Azaiez, PhD
      Sponsored By: Agilent
      11 8
      MAY 09, 2017 | 7:00 AM
      WEBINAR: Advanced assays for high-throughput assessment of ion channel inhibition and cardiac toxicity
      WEBINAR: Advanced assays for high-throughput assessment of ion...
      DATE: May 9th, 2017TIME: 7:00AM PDT, 10:00AM ET, 2:00PM GMT Early detection and elimination of new chemical entities with cardiac or hERG liability could substantially improve...
      Speaker: Beiyan Zou, PhD , Oksana Sirenko, PhD
      Sponsored By: Molecular Devices
      6
      MAY 03, 2017 | 10:00 AM
      What are the current advances in Flow Cytometry?
      What are the current advances in Flow Cytometry?
      DATE: May 3, 2017TIME: 10:00am PT, 1:00pm ETA number of new instruments have appeared in recent times to accommodate different applications and highlight technology advances. This webin...
      Speaker: J. Paul Robinson, PhD
      Presented at: Protein and Cell Analysis Education Series
      Sponsored By: Thermo Fisher Scientific
      12
      MAY 01, 2017 | 8:00 AM
      Using iPSCs and Genome Engineering to Build Disease Models
      Using iPSCs and Genome Engineering to Build Disease Models
      Developing therapies for human diseases continues to face obstacles, particularly in translating targets or compounds identified by in vitro screening campaigns to valid targets or efficaciou...
      Speaker: David Piper, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      1
      APR 19, 2017 | 4:00 AM
      WEBINAR: Patient Derived Micro Tumor systems: Future Trends towards improved testing systems
      WEBINAR: Patient Derived Micro Tumor systems: Future Trends towards...
      DATE: April 20th, 2017TIME: 10:00AM SGT, 11:00AM KST, 12:00PM AEST, 2:00PM NZSTWith increasing breadth and depth of genomics studies across a range of cancers, it is now apparent that t...
      Speaker: Giridharan Periyasamy, PhD
      Sponsored By: Revvity
      8
      APR 14, 2017 | 10:00 AM
      WEBINAR: Comparative Analysis of Plasma Lipid Alterations Associated with Age and Dietary Restriction using Targeted MS and Untargeted LC-MS Lipidomics Approaches
      WEBINAR: Comparative Analysis of Plasma Lipid Alterations Associated...
      DATE: April 14, 2017TIME: 10:00AM PST, 1:00PM ET The study presented will represent the most comprehensive characterization of lipid changes in the context of aging and DR to d...
      Speaker: Kévin Contrepois , PhD
      Sponsored By: SCIEX
      6 3
      APR 12, 2017 | 10:30 AM
      Prediction of enzalutamide sensitivity in triple negative breast cancer
      Prediction of enzalutamide sensitivity in triple negative breast...
      A recent clinical trial of the AR inhibitor enzalutamide in patients with TNBC included an exploratory endpoint using RNA sequencing to identify a genomic signature of patients likely to resp...
      Speaker: Joel Parker, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2017
      Sponsored By: NanoString Technologies
      2
      APR 06, 2017 | 7:00 AM
      WEBINAR: Colony picking in a fully automated DNA assembly workflow
      WEBINAR: Colony picking in a fully automated DNA assembly workflow
      DATE:  April 6, 2017TIME:  3:00PM GMT, 7:00AM PT, 10:00AM ETThe Edinburgh Genome Foundry (EGF) is a newly established facility of the University of Edinburgh and ass...
      Speaker: Ivan Yuan, PhD , Hille Tekotte, PhD , Valentin Zulkower, PhD
      Sponsored By: Molecular Devices
      6
    MAY 24, 2017 | 9:00 AM
    Strand NGS Server: or, why clinical bioinformaticians love Strand
    Strand NGS Server: or, why clinical bioinformaticians love Strand
    I’ll talk about Strand NGS Server, our server-client NGS offering. Strand NGS server is geared towards small-to-medium scale clinical labs with high-volume sequencing throughputs and lo...
    Speaker: Radhakrishna Bettadapura (RK), PhD
    Presented at: Lab Automation Virtual Event Series 2017
    Sponsored By: Strand
    3
    MAY 24, 2017 | 9:00 AM
    Fully Automated 3D Cell Culture for Human Cells
    Fully Automated 3D Cell Culture for Human Cells
    The consistent and optimized production of living human cells for drug discovery and regenerative medicine faces many challenges including the need for cost effective large scale expansion, i...
    Speaker: Robin Felder, PhD
    Presented at: Lab Automation Virtual Event Series 2017
    2
    MAY 24, 2017 | 7:30 AM
    Leveraging Recent Advances in Miltenyi's Cell Sorting Automation Platforms to Reduce Time to Data in Primary Cell-Based Assays.
    Leveraging Recent Advances in Miltenyi's Cell Sorting Automation...
    This seminar will give attendees a full overview of two new Miltenyi cell sorting platforms, the MultiMACS X and the CliniMACS Prodigy and how these instruments can be used in various primary...
    Speaker: Nick Trotter-Mayo, Ph.D. MBA
    Presented at: Lab Automation Virtual Event Series 2017
    Sponsored By: Miltenyi Biotec
    2
    MAY 24, 2017 | 7:30 AM
    Case Studies: Scaling Cell Therapy Manufacturing
    Case Studies: Scaling Cell Therapy Manufacturing
    Gain insights into T-cell expansion, viral vector production and scaling production of mesenchymal stem cells (MSCs) through the use of a functionally closed, automated, cell culture process....
    Speaker: Jim Beltzer, MS, PhD
    Presented at: Lab Automation Virtual Event Series 2017
    Sponsored By: TERUMO BCT
    1
    MAY 24, 2017 | 6:00 AM
    Robots in Research
    Robots in Research
    Often we are concerned at the thought of a lab run by robots, not humans-- but what if instead of having the world's brightest minds concerned with pipetting, blotting and scanning, there...
    Speaker: Mike Simson
    Presented at: Lab Automation Virtual Event Series 2017
    Sponsored By: Bosterbio
    1
     
     
  • MAY 24, 2017 | 6:00 AM
    Exploring Pharmacological Interactions with Matrix: The Innovations and Challenges of NCATS Drug Combination HTS Platform
    Exploring Pharmacological Interactions with Matrix: The Innovations...
    Acoustic dispensing technology has allowed for compound plating to be highly customizable depending upon scientific needs.  The ability to dispense compounds from a single well to any we...
    Speaker: Kelli Wilson, PhD
    Presented at: Lab Automation Virtual Event Series 2017
    3 1
    MAY 16, 2017 | 9:00 AM
    WEBINAR: Disease Models
    WEBINAR: Disease Models
    EVENT DETAILS:DATE: May 16, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science our first commit...
    Speaker: David Piper, PhD , Mark Kennedy, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    5 3
    MAY 11, 2017 | 12:00 PM
    Impact of Next-Generation Sequencing on Precision Medicine
    Impact of Next-Generation Sequencing on Precision Medicine
    It was 10 years ago that Illumina first launched the Genome Analyzer II, the world’s first high-throughput sequencing platform.  That system could produce one billion bps of sequen...
    Speaker: Gary Schroth,PhD
    Presented at: Genetics and Genomics Virtual Event Series 2017
    2
    MAY 11, 2017 | 10:30 AM
    C.E. CREDITS
    Functional Characterization of Gene Regulatory Elements
    Functional Characterization of Gene Regulatory Elements
    Nucleotide variation in gene regulatory elements is a major cause of human disease. Despite continual progress in the cataloging of these elements, little is known about the code and grammati...
    Speaker: Nadav Ahituv, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2017
    1
    MAY 10, 2017 | 2:00 PM
    Selecting the right resin to achieve optimal results, from high throughput batch to process scale protein purification
    Selecting the right resin to achieve optimal results, from high...
    The objective of academic, biotech or pharmaceutical scientists committed to protein purification is to obtain the purest protein needed for their application, regardless of scale. Towards th...
    Speaker: Aaron McBride , Scott Meier
    Presented at: 2017 Gibco ExpressionWorld
    7
     
     
  • MAY 10, 2017 | 1:00 PM
    Modification of Glycans in Bioprocessing
    Modification of Glycans in Bioprocessing
    Glycosylation is an important product quality attribute for biotherapeutic proteins expressed in CHO cells. Glycoform variability can significantly affect the safety and efficacy of therapeut...
    Speaker: Ryan Boniface
    Presented at: 2017 Gibco ExpressionWorld
    4
    MAY 10, 2017 | 12:00 PM
    Ask the Expert: Mammalian Transient Expression
    Ask the Expert: Mammalian Transient Expression
    Getting started Equipment Troubleshooting Scale up or scale down your expression runs Tackling difficult-to-express proteins 293 vs. CHO cell expression...
    Speaker: Henry Chiou, PhD , Richard Altman, MS , Jon Zmuda, PhD , Konrad Miatkowski
    Presented at: 2017 Gibco ExpressionWorld
    3
    MAY 10, 2017 | 11:00 AM
    An ongoing evaluation of our transient expression systems; Can we predict the appropriate expression system for any drug modality?
    An ongoing evaluation of our transient expression systems; Can...
    CHO cells are the predominant host for biotherapeutic protein expression with approximately 70% of licensed biologics manufactured in Chinese Hamster Ovary (CHO) cells.  The ability to e...
    Speaker: Richard Altman, MS
    Presented at: 2017 Gibco ExpressionWorld
    4
    MAY 10, 2017 | 10:30 AM
    C.E. CREDITS
    Methods to account for sequencing artifacts in large high-throughput RNA-Seq data
    Methods to account for sequencing artifacts in large high-throughput...
    Although ultrahigh-throughput RNA-sequencing has become the dominant technology for genome-wide transcriptional profiling, the vast majority of RNA-seq studies typically profile only tens of...
    Speaker: Joseph Paulson, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2017
    2
    MAY 10, 2017 | 9:00 AM
    A Semi-Automated High-Throughput Transient Expression and Purification Platform using the Expi293 Expression System
    A Semi-Automated High-Throughput Transient Expression and Purification...
    We have developed a semi-automated, high-throughput transient expression and purification system that yields milligram quantities of hundreds of proteins weekly. Starting from a glycerol stoc...
    Speaker: Matthew McKenna
    Presented at: 2017 Gibco ExpressionWorld
    4
     
     
  • MAY 10, 2017 | 6:00 AM
    C.E. CREDITS
    CATS - a novel library preparation method for ultrasensitive deep sequencing of extracellular circulating RNA and DNA
    CATS - a novel library preparation method for ultrasensitive deep...
    Massive parallel sequencing (MPS) technologies have paved the way into new areas of research including individualized medicine. However, sequencing of trace amounts of nucleic acids still rem...
    Speaker: Andrey Turchinovich, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2017
    Sponsored By: Diagenode
    4
    MAY 09, 2017 | 8:00 AM
    WEBINAR: Deafness in the Genomic Era: Discoveries, Challenges and Opportunities
    WEBINAR: Deafness in the Genomic Era: Discoveries, Challenges...
    DATE: May 9, 2017TIME: 8:00am PT, 11:00am ETHearing loss is the most common sensory defect in humans. It affects 360 million people worldwide and by 2020, that number is predi...
    Speaker: Hela Azaiez, PhD
    Sponsored By: Agilent
    11 8
    MAY 09, 2017 | 7:00 AM
    WEBINAR: Advanced assays for high-throughput assessment of ion channel inhibition and cardiac toxicity
    WEBINAR: Advanced assays for high-throughput assessment of ion...
    DATE: May 9th, 2017TIME: 7:00AM PDT, 10:00AM ET, 2:00PM GMT Early detection and elimination of new chemical entities with cardiac or hERG liability could substantially improve...
    Speaker: Beiyan Zou, PhD , Oksana Sirenko, PhD
    Sponsored By: Molecular Devices
    6
    MAY 03, 2017 | 10:00 AM
    What are the current advances in Flow Cytometry?
    What are the current advances in Flow Cytometry?
    DATE: May 3, 2017TIME: 10:00am PT, 1:00pm ETA number of new instruments have appeared in recent times to accommodate different applications and highlight technology advances. This webin...
    Speaker: J. Paul Robinson, PhD
    Presented at: Protein and Cell Analysis Education Series
    Sponsored By: Thermo Fisher Scientific
    12
    MAY 01, 2017 | 8:00 AM
    Using iPSCs and Genome Engineering to Build Disease Models
    Using iPSCs and Genome Engineering to Build Disease Models
    Developing therapies for human diseases continues to face obstacles, particularly in translating targets or compounds identified by in vitro screening campaigns to valid targets or efficaciou...
    Speaker: David Piper, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    1
     
     
  • APR 19, 2017 | 4:00 AM
    WEBINAR: Patient Derived Micro Tumor systems: Future Trends towards improved testing systems
    WEBINAR: Patient Derived Micro Tumor systems: Future Trends towards...
    DATE: April 20th, 2017TIME: 10:00AM SGT, 11:00AM KST, 12:00PM AEST, 2:00PM NZSTWith increasing breadth and depth of genomics studies across a range of cancers, it is now apparent that t...
    Speaker: Giridharan Periyasamy, PhD
    Sponsored By: Revvity
    8
    APR 14, 2017 | 10:00 AM
    WEBINAR: Comparative Analysis of Plasma Lipid Alterations Associated with Age and Dietary Restriction using Targeted MS and Untargeted LC-MS Lipidomics Approaches
    WEBINAR: Comparative Analysis of Plasma Lipid Alterations Associated...
    DATE: April 14, 2017TIME: 10:00AM PST, 1:00PM ET The study presented will represent the most comprehensive characterization of lipid changes in the context of aging and DR to d...
    Speaker: Kévin Contrepois , PhD
    Sponsored By: SCIEX
    6 3
    APR 12, 2017 | 10:30 AM
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    Speaker: Joel Parker, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2017
    Sponsored By: NanoString Technologies
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    APR 06, 2017 | 7:00 AM
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    Speaker: Ivan Yuan, PhD , Hille Tekotte, PhD , Valentin Zulkower, PhD
    Sponsored By: Molecular Devices
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