Laboratory Medicine: is where clinical tests are carried out to obtain information about the health of a patient to aid in diagnosis, treatment, and prevention of disease.
The laboratory animal industry had expanded rapidly in China recently. It is critical to have a good basic understanding of the domestic laws and regulations involving laboratory animals if a...
For the purpose of ensuring research integrity, data reproducibility, and animal welfare, institutions that conduct animal research have the responsibility to evaluate vendors that provide la...
This presentation mainly includes 4 sections, the first one: introduction for CFDA/FDA GLP Regulation and analysis the difference. The second one: introduction of the most important responsi...
The popularity reached by the genetic manipulation of laboratory animals to create new models for studying human diseases, produced in turn, that the techniques for assisted reproduction cons...
Although a growing body of evidence indicates that environmental enrichment (EE) facilitates normal development and behaviour in laboratory mice, few studies were conducted to demonstrate it...
With the growth and expansion of mouse and rat transgenic models in recent years, the demand for surgically altered models mimicking human diseases is growing at an amazing rate. Surgical pro...
Modern biomedical research greatly benefits from sophisticated techniques which can detect even the most subtle alterations between different individuals or groups. This has raised the bar fo...
It is increasingly recognized that the genetic background (i.e., all genomic sequences other than the gene(s) of interest) can have profound influences on the phenotype of an animal model. I...
Rabbits are commonly used in biomedical research for many years due to its ease of use and phylogenetical similarities with humans. They are commonly used in cardiovascular research (atherosc...
All personnel involved in an animal care and use program are expected to have an appropriate level of education, training and/or qualifications to perform their duties as defined through laws...
An anesthesia system designed to accommodate the physiological characteristics of small animals, including rats and mice, has the potential to provide great practical value to the life scien...
In the laboratory setting, rats are commonly housed in clear caging in brightly lit rooms. As their natural history suggests a preference for low-light conditions, this practice is likely str...
GOAL:"A simple and reliable method for mouse intubation" is designed as an instructional tutorial with learning objectives that are twofold. First is becoming familiar with the procedure an...
Nonhuman primates are commonly used in biomedical research due to its anatomical, behavioral, and genetic similarities with humans. Macaques, especially the Rhesus macaque (Macaca mulatta) ar...
Contract Research Organizations present unique challenges in the field of environmental enrichment for laboratory animals. CRO's are service oriented and budget conscious, with large animal p...
The 8th Edition of the Guide for the Care and Use of Laboratory Animals (Guide NRC, 2011) has been in use since 2011. What changes has it brought? What are the impacts of those changes? The g...
Simplifying Rodent Surgery... Tips for improving technique without incurring unreasonable costs Good science is greatly dependent on minimization of study variables. Surgery has the potential...
Pancreatic cancer is the 4th most common cause of cancer deaths in the United States. Due to the aggressive nature of this cancer and the lack of biomarkers for early detection, the incidence...
The discovery of proteinaceous disease biomarkers and their clinical validation is critically important for the enablement of molecular diagnostics and ultimately, precision medicine. In spit...
Prostate cancer epithelial cells depend on androgens for their survival. Because of this dependence, androgen deprivation therapy is the major treatment of advanced prostate cancer. Such ther...
Recent data have confirmed the ability of cardiac troponin (cTn) measurements to identify those who are developing cardiotoxicity in response to potentially cardiotoxic chemotherapeutic agen...
Cancer cells have historically been classified by microscopic analysis of blood smears and tissue sections. Current technologies use molecular techniques to categorize and classify tumor cell...
Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, a...
Cancer and diabetes are complex diseases that have proven difficult to treat in the clinics. Until recently, most efforts have focused on hitting individual therapeutic targets cleanly. Unfor...
The laboratory animal industry had expanded rapidly in China recently. It is critical to have a good basic understanding of the domestic laws and regulations involving laboratory animals if a...
For the purpose of ensuring research integrity, data reproducibility, and animal welfare, institutions that conduct animal research have the responsibility to evaluate vendors that provide la...
This presentation mainly includes 4 sections, the first one: introduction for CFDA/FDA GLP Regulation and analysis the difference. The second one: introduction of the most important responsi...
The popularity reached by the genetic manipulation of laboratory animals to create new models for studying human diseases, produced in turn, that the techniques for assisted reproduction cons...
Although a growing body of evidence indicates that environmental enrichment (EE) facilitates normal development and behaviour in laboratory mice, few studies were conducted to demonstrate it...
With the growth and expansion of mouse and rat transgenic models in recent years, the demand for surgically altered models mimicking human diseases is growing at an amazing rate. Surgical pro...
Modern biomedical research greatly benefits from sophisticated techniques which can detect even the most subtle alterations between different individuals or groups. This has raised the bar fo...
It is increasingly recognized that the genetic background (i.e., all genomic sequences other than the gene(s) of interest) can have profound influences on the phenotype of an animal model. I...
Rabbits are commonly used in biomedical research for many years due to its ease of use and phylogenetical similarities with humans. They are commonly used in cardiovascular research (atherosc...
All personnel involved in an animal care and use program are expected to have an appropriate level of education, training and/or qualifications to perform their duties as defined through laws...
An anesthesia system designed to accommodate the physiological characteristics of small animals, including rats and mice, has the potential to provide great practical value to the life scien...
In the laboratory setting, rats are commonly housed in clear caging in brightly lit rooms. As their natural history suggests a preference for low-light conditions, this practice is likely str...
GOAL:"A simple and reliable method for mouse intubation" is designed as an instructional tutorial with learning objectives that are twofold. First is becoming familiar with the procedure an...
Nonhuman primates are commonly used in biomedical research due to its anatomical, behavioral, and genetic similarities with humans. Macaques, especially the Rhesus macaque (Macaca mulatta) ar...
Contract Research Organizations present unique challenges in the field of environmental enrichment for laboratory animals. CRO's are service oriented and budget conscious, with large animal p...
The 8th Edition of the Guide for the Care and Use of Laboratory Animals (Guide NRC, 2011) has been in use since 2011. What changes has it brought? What are the impacts of those changes? The g...
Simplifying Rodent Surgery... Tips for improving technique without incurring unreasonable costs Good science is greatly dependent on minimization of study variables. Surgery has the potential...
Pancreatic cancer is the 4th most common cause of cancer deaths in the United States. Due to the aggressive nature of this cancer and the lack of biomarkers for early detection, the incidence...
The discovery of proteinaceous disease biomarkers and their clinical validation is critically important for the enablement of molecular diagnostics and ultimately, precision medicine. In spit...
Prostate cancer epithelial cells depend on androgens for their survival. Because of this dependence, androgen deprivation therapy is the major treatment of advanced prostate cancer. Such ther...
Recent data have confirmed the ability of cardiac troponin (cTn) measurements to identify those who are developing cardiotoxicity in response to potentially cardiotoxic chemotherapeutic agen...
Cancer cells have historically been classified by microscopic analysis of blood smears and tissue sections. Current technologies use molecular techniques to categorize and classify tumor cell...
Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, a...
Cancer and diabetes are complex diseases that have proven difficult to treat in the clinics. Until recently, most efforts have focused on hitting individual therapeutic targets cleanly. Unfor...
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