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    Targeted Therapy

    Targeted Therapy: one of the major modalities of medical treatment for cancer, others being hormonal therapy and cytotoxic chemotherapy.

    Webinars

    • APR 20, 2021 | 3:00 PM
      Panel Presentation: Accelerating precision oncology with matched FFPE and plasma biospecimens characterized using Discovery's SpecimenSeqâ„¢ NGS Service and QIAGEN's QIAseq Multimodal Panels
      Panel Presentation: Accelerating precision oncology with matched...
      Bridging a deep understanding of molecular profiles with clinical information is critical to developing innovative precision medicine tools in oncology. Discovery’s recently launched S...
      Speaker: Nathan Henson, MS , Donald Skifter, PhD, MBA
      Presented at: Genetics Week Virtual Event Series 2021
      Sponsored By: QIAGEN
      2
      APR 07, 2021 | 12:00 AM
      Niosomes as a bilayer nanocarrier for combinative drug delivery
      Niosomes as a bilayer nanocarrier for combinative drug delivery
      The past few decades have seen a substantial increase in the research based on nanocarrier based combinative drug therapies in various diseases such as cancer, tuberculosis, Alzheimer’...
      Speaker: Pratik Kulkarni, PhD
      Presented at: Bioprocessing Virtual Event Series 2021
      2
      MAR 30, 2021 | 8:00 AM
      Utilizing the Gibcoâ„¢ CTSâ„¢ Roteaâ„¢ System, a versatile closed manufacturing system, for cell and gene therapy development
      Utilizing the Gibcoâ„¢ CTSâ„¢ Roteaâ„¢ System, a versatile closed manufacturing...
      DATE: March 30, 2021 TIME: 08:00am PST In this talk, we will discuss the value of moving towards modular and automated, closed-system technologies designed to enable scalable and cost-effect...
      Speaker: Mary Ann Santos , Emily Benz , Eric Dubofsky
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      MAR 18, 2021 | 8:00 AM
      Facilitating transcriptomics of sensitive target cells with gentle cell sorting
      Facilitating transcriptomics of sensitive target cells with gentle...
      DATE: March 18, 2021 TIME: 8:00am PDT Sequencing of bulk cells, single cells, and nuclei is opening doors in the understanding of complex biological processes....
      Speaker: Alexander Jonsson , Dr. Alina Steinbach
      Sponsored By: Miltenyi Biotec
      11
      MAR 09, 2021 | 8:00 AM
      Ultrahigh-content imaging: a breath of fresh air for lung cancer research
      Ultrahigh-content imaging: a breath of fresh air for lung cancer...
      Date: March 09, 2021 Time: 8:00am (PST), 11:00am (EST) Lung cancer is one of the three most common types of cancer. Representing 85% of all lung cancers...
      Speaker: Dr. Telma Santos
      Sponsored By: Miltenyi Biotec
      13
      FEB 03, 2021 | 12:30 PM
      Optimizing High-Content Imaging of 3D Models for Drug Discovery
      Optimizing High-Content Imaging of 3D Models for Drug Discovery
      In vitro spheroid models are fast becoming the de facto standard for drug discovery applications, largely due to their human-like physiological and morphological characteristics, tissue-like...
      Speaker: Arvonn Tully , Judi Wardwell-Swanson
      Presented at: 7th Annual Conference: SBI2 High Content
      Sponsored By: SBI2, InSphero , Yokogawa
      11 10
      JAN 26, 2021 | 8:00 AM
      High-throughput CRISPR editing using the Onyxâ„¢ platform identifies essential residues in proteins
      High-throughput CRISPR editing using the Onyxâ„¢ platform identifies...
      Date: January 26, 2021 Time: 9:00am (PST), 12:00pm (EST) Over the past years, CRISPR/Cas genome editing has quickly become the method of choice for genetic manipulation, owing to its ease-of...
      Speaker: Liselot Dewachter, PhD , Laura Klitten, Ph.D.
      Sponsored By: Inscripta
      13 2
      JAN 19, 2021 | 8:00 AM
      The inhibitory role of specific macrophages in RCC
      The inhibitory role of specific macrophages in RCC
      Date: January 19, 2021 Time: 8:00am (PST), 11:00am (EST) Only a small subset of patients with clear cell Renal Cell Carcinoma (ccRCC) respond to immunotherapy with checkpoint inhibitors. Res...
      Speaker: Dr. Elfriede Nößner
      Sponsored By: Visiopharm®
      9
      DEC 03, 2020 | 4:30 PM
      An Iterative Approach to Structure-based in silico to in vivo Development of Combinatorial Anti-SARS-CoV-2 Therapy
      An Iterative Approach to Structure-based in silico to in vivo...
      This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
      Speaker: Garth Ehrlich, PhD, FAAAS
      Presented at: Coronavirus Series
      5
      DEC 02, 2020 | 8:00 AM
      Optimize your bioprocess - From shaker to bioreactor
      Optimize your bioprocess - From shaker to bioreactor
      DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
      Speaker: Ines Hartmann , David Solbach
      Sponsored By: Eppendorf
      11
      NOV 19, 2020 | 9:00 AM
      Highly specific multiplexed RNA imaging in tissues with split-FISH
      Highly specific multiplexed RNA imaging in tissues with split-FISH
      Date: November 19, 2020 Time: 12:00am (PDT), 9:00am (CET), 4:00pm (SGT) We present split-FISH, a multiplexed fluorescence in situ hybridization method that leverages a split-probe design to...
      Speaker: Kok Hao Chen , Alan Mullan, PhD
      Sponsored By: Andor
      6 2
      NOV 18, 2020 | 8:00 AM
      Whole-organ mapping using AI and light sheet microscopy
      Whole-organ mapping using AI and light sheet microscopy
      DATE: November 18, 2020 TIME: 08:00am PDT We develop and implement technologies to solve some of the major bottlenecks in biomedical research. In particular, we establish new imaging approac...
      Speaker: Ali Ertürk
      Sponsored By: Miltenyi Biotec
      14
      NOV 12, 2020 | 12:00 AM
      The Importance of Tissue Chemistry in Immunity-Oncology
      The Importance of Tissue Chemistry in Immunity-Oncology
      Cancer cells can acquire immune resistance resulting in a loss of immunosurveillance. Tumor cells can upregulate PDL-1 which binds to PD-1. This complex inhibits CD8 Tumor Infiltrating cells...
      Speaker: Thomas M. Grogan, MD
      Presented at: DISCOVERY Global User Symposium
      0
      NOV 12, 2020 | 12:00 AM
      Principles of Effective Method Development in Pathobiology Research
      Principles of Effective Method Development in Pathobiology Research
      Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
      Speaker: Vivian Barry, MS
      Presented at: DISCOVERY Global User Symposium
      2
      NOV 05, 2020 | 7:00 AM
      Stem cell derived exosome production in stirred-tank bioreactors
      Stem cell derived exosome production in stirred-tank bioreactors
      DATE: Date needed, 2020 TIME: Time needed Exosomes are a population of naturally occurring mobile, membrane-limited, 30 – 100 nm in diameter, extracellular vesicles containing a large...
      Speaker: Jorge Escobar , Aurélie Tacheny
      Presented at: Eppendorf Planet of Knowledge - A New Dimension
      Sponsored By: Eppendorf
      12
      NOV 04, 2020 | 11:00 AM
      Developing flow-based analytical methods for gene-edited CAR-T programs: How to ensure an efficient transition from early research to clinical development
      Developing flow-based analytical methods for gene-edited CAR-T...
      DATE: November 4th, 2020 TIME: 11:00am PST As cell therapies become more complex, the need for robust analytical tools to characterize such products as they enter the clinic has increased in...
      Speaker: Aaron Edwards
      Sponsored By: Miltenyi Biotec
      6
      OCT 21, 2020 | 10:35 PM
      Latest Developments with the Genexus System
      Latest Developments with the Genexus System
      The treatment of cancer has remarkably improved because of increased knowledge of the molecular abnormalities that drive human cancer growth. This has led to the development of ever more eff...
      Speaker: Dr. Jose Luis Costa
      Presented at: OncomineWorld Autumn: A virtual NGS education meeting
      1
      OCT 21, 2020 | 10:35 PM
      Latest Developments with the Genexus System
      Latest Developments with the Genexus System
      The treatment of cancer has remarkably improved because of increased knowledge of the molecular abnormalities that drive human cancer growth. This has led to the development of ever more eff...
      Speaker: Dr. Jose Luis Costa
      Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
      0
      OCT 21, 2020 | 9:05 PM
      Incorporating NGS in an Asian non-small cell lung cancer (NSCLC) population - a cost-effectiveness analysis
      Incorporating NGS in an Asian non-small cell lung cancer (NSCLC)...
      There is an expanding list of therapeutically relevant biomarkers for non-small cell lung cancer (NSCLC), and molecular profiling at diagnosis is paramount. Tissue attrition in scaling tradi...
      Speaker: Aaron Tan, PhD
      Presented at: OncomineWorld Autumn: A virtual NGS education meeting
      1
      OCT 21, 2020 | 9:05 PM
      Incorporating NGS in an Asian non-small cell lung cancer (NSCLC) population - a cost-effectiveness analysis
      Incorporating NGS in an Asian non-small cell lung cancer (NSCLC)...
      There is an expanding list of therapeutically relevant biomarkers for non-small cell lung cancer (NSCLC), and molecular profiling at diagnosis is paramount. Tissue attrition in scaling tradi...
      Speaker: Aaron Tan, PhD
      Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
      0
      OCT 21, 2020 | 9:00 AM
      Managing and Monitoring Inflammatory Bowel Disease
      Managing and Monitoring Inflammatory Bowel Disease
      DATE: October 21, 2020 TIME: 08:00am PT Learning Objectives: Describe Inflammatory Bowel Disease (IBD) pathophysiology and epidemiology Understand treat to target goals Review role of fecal...
      Speaker: Dr. Anita Afzali
      Sponsored By: Diasorin S.p.A.
      13
      OCT 20, 2020 | 9:00 AM
      Understanding how in vitro macrophage assays drive IO drug development forward
      Understanding how in vitro macrophage assays drive IO drug development...
      DATE: October 20th, 2020 TIME: 08:00am PT, 11:00am ET Tumor-associated macrophages (TAMs) are key cells in the tumor microenvironment (TME) with diverse immune functions that have a major in...
      Speaker: Thibaut Janss, PhD
      Sponsored By: Miltenyi Biotec
      6 1
      OCT 08, 2020 | 6:00 PM
      Multimodal analysis of circulating cell-free RNA (ccfRNA), cell-free DNA (ccfDNA), genomic DNA (gDNA) and CTCs from blood samples in cancer research
      Multimodal analysis of circulating cell-free RNA (ccfRNA), cell-free...
      While circulating cell-free DNA (ccfDNA) and to some extend CTCs from blood are routinely used as analyte in liquid biopsy cancer research applications, circulating cell-free RNA (ccfRNA) ha...
      Speaker: Thorsten Voss, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: QIAGEN
      4
      OCT 08, 2020 | 6:00 PM
      High-throughput biomarker profiling in immuno-oncology research & development
      High-throughput biomarker profiling in immuno-oncology research...
      Soluble cytokine biomarkers are the master regulators of cell-to-cell communication-- the means by which one cell tells another what to do or where to go. Determining the biomarker signature...
      Speaker: Jenny Koenitzer, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      3
    APR 20, 2021 | 3:00 PM
    Panel Presentation: Accelerating precision oncology with matched FFPE and plasma biospecimens characterized using Discovery's SpecimenSeqâ„¢ NGS Service and QIAGEN's QIAseq Multimodal Panels
    Panel Presentation: Accelerating precision oncology with matched...
    Bridging a deep understanding of molecular profiles with clinical information is critical to developing innovative precision medicine tools in oncology. Discovery’s recently launched S...
    Speaker: Nathan Henson, MS , Donald Skifter, PhD, MBA
    Presented at: Genetics Week Virtual Event Series 2021
    Sponsored By: QIAGEN
    2
    APR 07, 2021 | 12:00 AM
    Niosomes as a bilayer nanocarrier for combinative drug delivery
    Niosomes as a bilayer nanocarrier for combinative drug delivery
    The past few decades have seen a substantial increase in the research based on nanocarrier based combinative drug therapies in various diseases such as cancer, tuberculosis, Alzheimer’...
    Speaker: Pratik Kulkarni, PhD
    Presented at: Bioprocessing Virtual Event Series 2021
    2
    MAR 30, 2021 | 8:00 AM
    Utilizing the Gibcoâ„¢ CTSâ„¢ Roteaâ„¢ System, a versatile closed manufacturing system, for cell and gene therapy development
    Utilizing the Gibcoâ„¢ CTSâ„¢ Roteaâ„¢ System, a versatile closed manufacturing...
    DATE: March 30, 2021 TIME: 08:00am PST In this talk, we will discuss the value of moving towards modular and automated, closed-system technologies designed to enable scalable and cost-effect...
    Speaker: Mary Ann Santos , Emily Benz , Eric Dubofsky
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
    MAR 18, 2021 | 8:00 AM
    Facilitating transcriptomics of sensitive target cells with gentle cell sorting
    Facilitating transcriptomics of sensitive target cells with gentle...
    DATE: March 18, 2021 TIME: 8:00am PDT Sequencing of bulk cells, single cells, and nuclei is opening doors in the understanding of complex biological processes....
    Speaker: Alexander Jonsson , Dr. Alina Steinbach
    Sponsored By: Miltenyi Biotec
    11
    MAR 09, 2021 | 8:00 AM
    Ultrahigh-content imaging: a breath of fresh air for lung cancer research
    Ultrahigh-content imaging: a breath of fresh air for lung cancer...
    Date: March 09, 2021 Time: 8:00am (PST), 11:00am (EST) Lung cancer is one of the three most common types of cancer. Representing 85% of all lung cancers...
    Speaker: Dr. Telma Santos
    Sponsored By: Miltenyi Biotec
    13
     
     
  • FEB 03, 2021 | 12:30 PM
    Optimizing High-Content Imaging of 3D Models for Drug Discovery
    Optimizing High-Content Imaging of 3D Models for Drug Discovery
    In vitro spheroid models are fast becoming the de facto standard for drug discovery applications, largely due to their human-like physiological and morphological characteristics, tissue-like...
    Speaker: Arvonn Tully , Judi Wardwell-Swanson
    Presented at: 7th Annual Conference: SBI2 High Content
    Sponsored By: SBI2, InSphero , Yokogawa
    11 10
    JAN 26, 2021 | 8:00 AM
    High-throughput CRISPR editing using the Onyxâ„¢ platform identifies essential residues in proteins
    High-throughput CRISPR editing using the Onyxâ„¢ platform identifies...
    Date: January 26, 2021 Time: 9:00am (PST), 12:00pm (EST) Over the past years, CRISPR/Cas genome editing has quickly become the method of choice for genetic manipulation, owing to its ease-of...
    Speaker: Liselot Dewachter, PhD , Laura Klitten, Ph.D.
    Sponsored By: Inscripta
    13 2
    JAN 19, 2021 | 8:00 AM
    The inhibitory role of specific macrophages in RCC
    The inhibitory role of specific macrophages in RCC
    Date: January 19, 2021 Time: 8:00am (PST), 11:00am (EST) Only a small subset of patients with clear cell Renal Cell Carcinoma (ccRCC) respond to immunotherapy with checkpoint inhibitors. Res...
    Speaker: Dr. Elfriede Nößner
    Sponsored By: Visiopharm®
    9
    DEC 03, 2020 | 4:30 PM
    An Iterative Approach to Structure-based in silico to in vivo Development of Combinatorial Anti-SARS-CoV-2 Therapy
    An Iterative Approach to Structure-based in silico to in vivo...
    This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
    Speaker: Garth Ehrlich, PhD, FAAAS
    Presented at: Coronavirus Series
    5
    DEC 02, 2020 | 8:00 AM
    Optimize your bioprocess - From shaker to bioreactor
    Optimize your bioprocess - From shaker to bioreactor
    DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
    Speaker: Ines Hartmann , David Solbach
    Sponsored By: Eppendorf
    11
     
     
  • NOV 19, 2020 | 9:00 AM
    Highly specific multiplexed RNA imaging in tissues with split-FISH
    Highly specific multiplexed RNA imaging in tissues with split-FISH
    Date: November 19, 2020 Time: 12:00am (PDT), 9:00am (CET), 4:00pm (SGT) We present split-FISH, a multiplexed fluorescence in situ hybridization method that leverages a split-probe design to...
    Speaker: Kok Hao Chen , Alan Mullan, PhD
    Sponsored By: Andor
    6 2
    NOV 18, 2020 | 8:00 AM
    Whole-organ mapping using AI and light sheet microscopy
    Whole-organ mapping using AI and light sheet microscopy
    DATE: November 18, 2020 TIME: 08:00am PDT We develop and implement technologies to solve some of the major bottlenecks in biomedical research. In particular, we establish new imaging approac...
    Speaker: Ali Ertürk
    Sponsored By: Miltenyi Biotec
    14
    NOV 12, 2020 | 12:00 AM
    The Importance of Tissue Chemistry in Immunity-Oncology
    The Importance of Tissue Chemistry in Immunity-Oncology
    Cancer cells can acquire immune resistance resulting in a loss of immunosurveillance. Tumor cells can upregulate PDL-1 which binds to PD-1. This complex inhibits CD8 Tumor Infiltrating cells...
    Speaker: Thomas M. Grogan, MD
    Presented at: DISCOVERY Global User Symposium
    0
    NOV 12, 2020 | 12:00 AM
    Principles of Effective Method Development in Pathobiology Research
    Principles of Effective Method Development in Pathobiology Research
    Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
    Speaker: Vivian Barry, MS
    Presented at: DISCOVERY Global User Symposium
    2
    NOV 05, 2020 | 7:00 AM
    Stem cell derived exosome production in stirred-tank bioreactors
    Stem cell derived exosome production in stirred-tank bioreactors
    DATE: Date needed, 2020 TIME: Time needed Exosomes are a population of naturally occurring mobile, membrane-limited, 30 – 100 nm in diameter, extracellular vesicles containing a large...
    Speaker: Jorge Escobar , Aurélie Tacheny
    Presented at: Eppendorf Planet of Knowledge - A New Dimension
    Sponsored By: Eppendorf
    12
     
     
  • NOV 04, 2020 | 11:00 AM
    Developing flow-based analytical methods for gene-edited CAR-T programs: How to ensure an efficient transition from early research to clinical development
    Developing flow-based analytical methods for gene-edited CAR-T...
    DATE: November 4th, 2020 TIME: 11:00am PST As cell therapies become more complex, the need for robust analytical tools to characterize such products as they enter the clinic has increased in...
    Speaker: Aaron Edwards
    Sponsored By: Miltenyi Biotec
    6
    OCT 21, 2020 | 10:35 PM
    Latest Developments with the Genexus System
    Latest Developments with the Genexus System
    The treatment of cancer has remarkably improved because of increased knowledge of the molecular abnormalities that drive human cancer growth. This has led to the development of ever more eff...
    Speaker: Dr. Jose Luis Costa
    Presented at: OncomineWorld Autumn: A virtual NGS education meeting
    1
    OCT 21, 2020 | 10:35 PM
    Latest Developments with the Genexus System
    Latest Developments with the Genexus System
    The treatment of cancer has remarkably improved because of increased knowledge of the molecular abnormalities that drive human cancer growth. This has led to the development of ever more eff...
    Speaker: Dr. Jose Luis Costa
    Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
    0
    OCT 21, 2020 | 9:05 PM
    Incorporating NGS in an Asian non-small cell lung cancer (NSCLC) population - a cost-effectiveness analysis
    Incorporating NGS in an Asian non-small cell lung cancer (NSCLC)...
    There is an expanding list of therapeutically relevant biomarkers for non-small cell lung cancer (NSCLC), and molecular profiling at diagnosis is paramount. Tissue attrition in scaling tradi...
    Speaker: Aaron Tan, PhD
    Presented at: OncomineWorld Autumn: A virtual NGS education meeting
    1
    OCT 21, 2020 | 9:05 PM
    Incorporating NGS in an Asian non-small cell lung cancer (NSCLC) population - a cost-effectiveness analysis
    Incorporating NGS in an Asian non-small cell lung cancer (NSCLC)...
    There is an expanding list of therapeutically relevant biomarkers for non-small cell lung cancer (NSCLC), and molecular profiling at diagnosis is paramount. Tissue attrition in scaling tradi...
    Speaker: Aaron Tan, PhD
    Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
    0
     
     
  • OCT 21, 2020 | 9:00 AM
    Managing and Monitoring Inflammatory Bowel Disease
    Managing and Monitoring Inflammatory Bowel Disease
    DATE: October 21, 2020 TIME: 08:00am PT Learning Objectives: Describe Inflammatory Bowel Disease (IBD) pathophysiology and epidemiology Understand treat to target goals Review role of fecal...
    Speaker: Dr. Anita Afzali
    Sponsored By: Diasorin S.p.A.
    13
    OCT 20, 2020 | 9:00 AM
    Understanding how in vitro macrophage assays drive IO drug development forward
    Understanding how in vitro macrophage assays drive IO drug development...
    DATE: October 20th, 2020 TIME: 08:00am PT, 11:00am ET Tumor-associated macrophages (TAMs) are key cells in the tumor microenvironment (TME) with diverse immune functions that have a major in...
    Speaker: Thibaut Janss, PhD
    Sponsored By: Miltenyi Biotec
    6 1
    OCT 08, 2020 | 6:00 PM
    Multimodal analysis of circulating cell-free RNA (ccfRNA), cell-free DNA (ccfDNA), genomic DNA (gDNA) and CTCs from blood samples in cancer research
    Multimodal analysis of circulating cell-free RNA (ccfRNA), cell-free...
    While circulating cell-free DNA (ccfDNA) and to some extend CTCs from blood are routinely used as analyte in liquid biopsy cancer research applications, circulating cell-free RNA (ccfRNA) ha...
    Speaker: Thorsten Voss, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: QIAGEN
    4
    OCT 08, 2020 | 6:00 PM
    High-throughput biomarker profiling in immuno-oncology research & development
    High-throughput biomarker profiling in immuno-oncology research...
    Soluble cytokine biomarkers are the master regulators of cell-to-cell communication-- the means by which one cell tells another what to do or where to go. Determining the biomarker signature...
    Speaker: Jenny Koenitzer, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    3
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