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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
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MAR 04, 2017Cell & Molecular Biology
A special biological property that is not well known or understood seems to enable cellular structures to store energy a ...Written By: Carmen LeitchMAR 03, 2017Cell & Molecular Biology
While we may think of our genome as being relatively stable an unchanging, but there are many opportunities for subtle a ...Written By: Carmen LeitchMAR 01, 2017Plants & Animals
When it comes to the world of chickens, some breeds are more readily available than others, and this tends to be a probl ...Written By: Anthony BouchardFEB 28, 2017Cell & Molecular Biology
Scientists have been trying to use the body's natural defenses to fight successfully against cancer, a promising idea st ...Written By: Carmen LeitchFEB 26, 2017Cardiology
Pulmonary fibrosis can inhibit breathing due to scarring in the lungs. However, fibrosis is not limited to the lungs; it ...Written By: Kara MarkerFEB 24, 2017Cell & Molecular Biology
A modification to DNA called methylation has been connected to obesity. It is known that many changes are made to genes ...Written By: Carmen LeitchFEB 24, 2017Cell & Molecular Biology
Genes are the blueprint for an organism, they contain the instructions to build functional cells. But those instructiona ...Written By: Carmen LeitchFEB 24, 2017Microbiology
Researchers from Harvard Medical School have reported on the results of a large-scale search for immunomodulatory organi ...Written By: Kerry EvansFEB 23, 2017Cell & Molecular Biology
Using cells in culture for biomedical research usually involves taking an entire population, rather than i ...Written By: Carmen LeitchFEB 22, 2017Videos
The human brain is still a mysterious organ. It's challenging to study the structure and function of such a delicate org ...Written By: Carmen LeitchFEB 22, 2017Cell & Molecular Biology
Stem cells are still not well understood, but there is a lot of interest in knowing more about them for many reasons; th ...Written By: Carmen LeitchFEB 21, 2017Cell & Molecular Biology
Understanding more about an organism's ability to regenerate could help us develop therapeutics for serious injury o ...Written By: Carmen LeitchFEB 21, 2017Immunology
Human immunodeficiency virus, notoriously known as HIV, appears untouchable by the immune system, resulting in millions ...Written By: Kara MarkerFEB 20, 2017Cell & Molecular Biology
A new molecule has been found and it could help in the development of new antibiotics – a major priority for publi ...Written By: Carmen LeitchFEB 17, 2017Cell & Molecular Biology
Brain tumors are difficult to detect, often only becoming apparent long after symptoms like seizures have begun. New wor ...Written By: Carmen LeitchFEB 16, 2017Cell & Molecular Biology
The CRISPR/Cas9 genome editing system has made a tremendous impact in the years since it's development. Scientists h ...Written By: Carmen LeitchFEB 16, 2017Space & Astronomy
NASA is very interested in learning exactly how long term space missions affect the human body, and thanks to the experi ...Written By: Anthony BouchardFEB 16, 2017Microbiology
Spoiler alert, you’re infected with Epstein-Barr virus. Well, you’re probably infected - nearly 98% of peopl ...Written By: Kerry EvansFEB 15, 2017Cell & Molecular Biology
Stem cells have gained fame for their ability to become any type of cell in the body. Unlike specialized cells with very ...Written By: Carmen LeitchFEB 15, 2017Cardiology
The heart’s four chambers, made up of left and right atria and ventricles, work together in an amazingly intricate ...Written By: Kara MarkerFEB 15, 2017Neuroscience
Head injuries are always dangerous, even if they first appear to be minor. From just a small bump to a full on Trau ...Written By: Brenda Kelley KimFEB 14, 2017Cell & Molecular Biology
New work has demonstrated that bone injuries can be repaired using a sheet of a carbon compound that has photocatalytic ...Written By: Carmen LeitchFEB 14, 2017Plants & Animals
Scientists have identified a substance in oil that’s to blame for the cardiotoxicity seen in fish exposed to crude ...Written By: Futurity (futurity.org)FEB 13, 2017Cell & Molecular Biology
Research teams have made progress in the study of a group of common genetic diseases termed RASopathies because they are ...Written By: Carmen Leitch
MAR 04, 2017
Cell & Molecular Biology
A special biological property that is not well known or understood seems to enable cellular structures to store energy a
...
Written By:
Carmen Leitch
MAR 03, 2017
Cell & Molecular Biology
While we may think of our genome as being relatively stable an unchanging, but there are many opportunities for subtle a
...
Written By:
Carmen Leitch
MAR 01, 2017
Plants & Animals
When it comes to the world of chickens, some breeds are more readily available than others, and this tends to be a probl
...
Written By:
Anthony Bouchard
FEB 28, 2017
Cell & Molecular Biology
Scientists have been trying to use the body's natural defenses to fight successfully against cancer, a promising idea st
...
Written By:
Carmen Leitch
FEB 26, 2017
Cardiology
Pulmonary fibrosis can inhibit breathing due to scarring in the lungs. However, fibrosis is not limited to the lungs; it
...
Written By:
Kara Marker
FEB 24, 2017
Cell & Molecular Biology
A modification to DNA called methylation has been connected to obesity. It is known that many changes are made to genes
...
Written By:
Carmen Leitch
FEB 24, 2017
Cell & Molecular Biology
Genes are the blueprint for an organism, they contain the instructions to build functional cells. But those instructiona
...
Written By:
Carmen Leitch
FEB 24, 2017
Microbiology
Researchers from Harvard Medical School have reported on the results of a large-scale search for immunomodulatory organi
...
Written By:
Kerry Evans
FEB 23, 2017
Cell & Molecular Biology
Using cells in culture for biomedical research usually involves taking an entire population, rather than i
...
Written By:
Carmen Leitch
FEB 22, 2017
Videos
The human brain is still a mysterious organ. It's challenging to study the structure and function of such a delicate org
...
Written By:
Carmen Leitch
FEB 22, 2017
Cell & Molecular Biology
Stem cells are still not well understood, but there is a lot of interest in knowing more about them for many reasons; th
...
Written By:
Carmen Leitch
FEB 21, 2017
Cell & Molecular Biology
Understanding more about an organism's ability to regenerate could help us develop therapeutics for serious injury o
...
Written By:
Carmen Leitch
FEB 21, 2017
Immunology
Human immunodeficiency virus, notoriously known as HIV, appears untouchable by the immune system, resulting in millions
...
Written By:
Kara Marker
FEB 20, 2017
Cell & Molecular Biology
A new molecule has been found and it could help in the development of new antibiotics – a major priority for publi
...
Written By:
Carmen Leitch
FEB 17, 2017
Cell & Molecular Biology
Brain tumors are difficult to detect, often only becoming apparent long after symptoms like seizures have begun. New wor
...
Written By:
Carmen Leitch
FEB 16, 2017
Cell & Molecular Biology
The CRISPR/Cas9 genome editing system has made a tremendous impact in the years since it's development. Scientists h
...
Written By:
Carmen Leitch
FEB 16, 2017
Space & Astronomy
NASA is very interested in learning exactly how long term space missions affect the human body, and thanks to the experi
...
Written By:
Anthony Bouchard
FEB 16, 2017
Microbiology
Spoiler alert, you’re infected with Epstein-Barr virus. Well, you’re probably infected - nearly 98% of peopl
...
Written By:
Kerry Evans
FEB 15, 2017
Cell & Molecular Biology
Stem cells have gained fame for their ability to become any type of cell in the body. Unlike specialized cells with very
...
Written By:
Carmen Leitch
FEB 15, 2017
Cardiology
The heart’s four chambers, made up of left and right atria and ventricles, work together in an amazingly intricate
...
Written By:
Kara Marker
FEB 15, 2017
Neuroscience
Head injuries are always dangerous, even if they first appear to be minor. From just a small bump to a full on Trau
...
Written By:
Brenda Kelley Kim
FEB 14, 2017
Cell & Molecular Biology
New work has demonstrated that bone injuries can be repaired using a sheet of a carbon compound that has photocatalytic
...
Written By:
Carmen Leitch
FEB 14, 2017
Plants & Animals
Scientists have identified a substance in oil that’s to blame for the cardiotoxicity seen in fish exposed to crude
...
Written By:
Futurity (futurity.org)
FEB 13, 2017
Cell & Molecular Biology
Research teams have made progress in the study of a group of common genetic diseases termed RASopathies because they are
...
Written By:
Carmen Leitch