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    Cell Line Development

    Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.

    Webinars

    • MAR 19, 2015 | 9:00 AM
      Keynote - Impulsivity and Compulsivity: Neural Substrates and Neuropsychiatric Implications
      Keynote - Impulsivity and Compulsivity: Neural Substrates and...
      Impulsivity can be defined as the tendency to act prematurely without foresight. Behavioural and neurobiological analysis of this construct, based on evidence from both animal and human studi...
      Speaker: Trevor Robbins, CBE FRS FMedSci FBPsS
      Presented at: Neuroscience Virtual Event Series 2015
      12
      MAR 18, 2015 | 3:00 PM
      The Human Connectome Project
      The Human Connectome Project
      Recent advances in noninvasive neuroimaging have set the stage for the systematic exploration of human brain circuits in health and disease. The Human Connectome Project (HCP) is systematical...
      Speaker: David Van Essen, PhD
      Presented at: Neuroscience Virtual Event Series 2015
      10
      MAR 18, 2015 | 12:00 PM
      Keynote - Psychosis as a Learning and Memory Disorder
      Keynote - Psychosis as a Learning and Memory Disorder
      The hippocampal formation is one of the most extensively studied regions of the brain, with well described anatomy and basic physiology; moreover, aspects of human memory mediated by hippocam...
      Speaker: Carol Tamminga, MD
      Presented at: Neuroscience Virtual Event Series 2015
      10
      MAR 18, 2015 | 9:00 AM
      Special Lecturer - DREADD2.0: an Enhanced Chemogenetic Toolkit
      Special Lecturer - DREADD2.0: an Enhanced Chemogenetic Toolkit
      The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative has the ambitious goal of elucidating how neuronal ensembles interactively encode higher brain processes....
      Speaker: Bryan L. Roth, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2015
      14
      MAR 18, 2015 | 7:30 AM
      Special Lecturer - Circuits of Reward/Motivation and Decisions: Linking Connectivity to Function and Disease
      Special Lecturer - Circuits of Reward/Motivation and Decisions:...
      The dorsal anterior cingulate cortex (dACC), orbitofrontal cortex (OFC), ventrolateral and ventromedial prefrontal cortex (vlPFC, vmPFC) and their connections with the basal ganglia play a ce...
      Speaker: Suzanne Haber, PhD
      Presented at: Neuroscience Virtual Event Series 2015
      14
      MAR 10, 2015 | 9:00 AM
      Newly Updated Guidelines for the Diagnosis of Multiple Myeloma
      Newly Updated Guidelines for the Diagnosis of Multiple Myeloma
      DATE: Tuesday, March 10, 2015 TIME: 09:00 PST, 11:00 CST, 12:00 EST, 16:00 GMTThe International Myeloma Working Group (IMWG) has issued updated criteria for the diagnosis of multiple...
      Speaker: Ola Landgren, M.D., Ph.D.
      Sponsored By: Binding Site, Binding Site
      17 7
      FEB 19, 2015 | 8:00 AM
      Presenting a complete workflow - from start to finish!
      Presenting a complete workflow - from start to finish!
      For more on Gene Editing watch “Webinar: Improve CRISPR-Cas9 experiments with rationally designed guide RNAs” The CRISPR-Cas9 system is being widely used for genome engineering...
      Speaker: Emily Anderson, Ph.D.
      Sponsored By: Dharmacon, Dharmacon
      34 1
      FEB 04, 2015 | 1:30 PM
      C.E. CREDITS
      The Surgeons Toolbox: outcomes are only as good as the contents of the box
      The Surgeons Toolbox: outcomes are only as good as the contents...
      The field of surgical research has been growing rapidly with the development of new surgical and disease models. An extremely important and often overlooked aspect of creating these models is...
      Speaker: Szczepan Baran, VMD, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      4
      FEB 04, 2015 | 7:30 AM
      C.E. CREDITS
      Normal behavior of rodents: understand it, then respect it
      Normal behavior of rodents: understand it, then respect it
      During my presentation, we will discuss:- Normal patterns of behavior (repertoire): social, food intake, territorial, agonistic, anti-predation, sleep and rest, play behavior, grooming, sex...
      Speaker: Marina Snitcofsky, DVM, MSc, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      7
      JAN 26, 2015 | 8:00 AM
      How stem cells speak with immune cells
      How stem cells speak with immune cells
      Advances in stem cell biology have raised great expectations that diseases of the central nervous system may be ameliorated by the development of non-haematopoietic stem cell medicines. Yet,...
      Speaker: Stefano Pluchino, MD, PhD
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      19 2
      JAN 21, 2015 | 10:00 PM
      NGS-Quality Sample Preparation with Covaris Adaptive Focused Acoustics (AFAâ„¢)
      NGS-Quality Sample Preparation with Covaris Adaptive Focused Acoustics...
       In this presentation we will illustrate the advantages of AFA technology in clinically significant applications (NGS, FFPE, ChIP) and will demonstrate the flexibility of Covaris AFA in deliv...
      Speaker: Hamid Khoja Ph.D.
      Sponsored By: Covaris, Inc., Covaris, Inc.
      8
      JAN 09, 2015 | 5:30 AM
      Optimizing Workflows in Flow Cytometry
      Optimizing Workflows in Flow Cytometry
        In this webinar, the presenter will discuss:      An Introduction to EPFL’s Core Facility and its role in furthering flow cytometry research   &nb...
      Speaker: Loïc Tauzin
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      13
      OCT 30, 2014 | 3:00 PM
      Clinical Shotgun Proteomics in Cancer Biomarker and Drug Target Research/Discovery
      Clinical Shotgun Proteomics in Cancer Biomarker and Drug Target...
      Mass spectrometry (MS)-based profiling of clinical specimens has been increasingly used in cancer research to characterize changes in protein expression between tumor and healthy tissue or be...
      Speaker: Josip Blonder, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      30
      OCT 30, 2014 | 10:30 AM
      Development of molecularly targeted imaging agents and identification of novel targets in cancer
      Development of molecularly targeted imaging agents and identification...
      The era of omics has ushered in the hope for personalized medicine. Proteomic and genomic strategies that allow unbiased identification of genes and proteins and their post-transcriptional a...
      Speaker: Kimberly Kelly , PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      16
      OCT 30, 2014 | 9:00 AM
      A head-to-head comparison of whole blood derived samples (cfDNA vs CTC DNA) for cancer research using next-generation sequencing
      A head-to-head comparison of whole blood derived samples (cfDNA...
      Both cell free DNA (cfDNA) and circulating tumor cells (CTC) represent important possible templates for mutation analysis of clinical samples. Each template has different theoretical advantag...
      Speaker: Paul W. Dempsey, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      0
      OCT 29, 2014 | 3:00 PM
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
      Speaker: Michael J Mann, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      67
      OCT 29, 2014 | 9:00 AM
      Reading and disrupting the histone code with chemical agents: making new tools to understand epigenetic methylation pathways in stem-like cancers
      Reading and disrupting the histone code with chemical agents:...
      Post-translational methylations play central roles in epigenetic gene regulation pathways that are central to stem cell regulation. Lysine methylations are turn-on switches for hundreds of di...
      Speaker: Fraser Hof, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      7
      OCT 29, 2014 | 7:30 AM
      Antibody-based Proteomics: Fast-Tracking Molecular Diagnostics and Target Discovery in Oncology
      Antibody-based Proteomics: Fast-Tracking Molecular Diagnostics...
      The effective implementation of personalised cancer therapeutic regimens depends on the successful identification and translation of informative biomarkers to aid clinical decision-making. An...
      Speaker: Darran O'Connor, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      6
      SEP 24, 2014 | 2:00 PM
      Development and Applications of CRISPR-Cas9 for Genome Editing
      Development and Applications of CRISPR-Cas9 for Genome Editing
      The RNA-guided nuclease Cas9 from the microbial CRISPR adaptive immune system has emerged as an exciting tool for precise genome editing in eukaryotic cells. This presentation will discuss th...
      Speaker: Feng Zhang, Ph.D.
      Presented at: Advances in Drug Discovery and Development
      39
      SEP 24, 2014 | 11:00 AM
      Drug Repositioning in the Era of Personalized Medicine
      Drug Repositioning in the Era of Personalized Medicine
      This presentation will focus on NuMediis general approach towards the discovery of new therapeutic uses for existing drugs. While the business models for repurposing marketed drugs versus rep...
      Speaker: Craig Webb, Ph.D.
      Presented at: Advances in Drug Discovery and Development
      32
      SEP 24, 2014 | 11:00 AM
      Structure based Drug Design for G-protein coupled receptors using the StaR(r) technology
      Structure based Drug Design for G-protein coupled receptors using...
      Heptares Therapeutics is a structure based drug discovery and development company which uses it StaR technology to enable X-ray structures, fragment screening and other biophysical techniques...
      Speaker: Fiona Marshall, PhD
      Presented at: Advances in Drug Discovery and Development
      10
      SEP 24, 2014 | 8:00 AM
      Role of Academic Institutions in Target Selection
      Role of Academic Institutions in Target Selection
      Target selection is arguably the most important decision in all drug discovery and development activities. No amount of great science can overcome the selection of the wrong target. The rapid...
      Speaker: Michael A. Foley, Ph.D.
      Presented at: Advances in Drug Discovery and Development
      32
      AUG 21, 2014 | 6:45 AM
      Development and Applications of CRISPR-Cas9 for Genome Editing
      Development and Applications of CRISPR-Cas9 for Genome Editing
      The Cas9 endonuclease from the microbial adaptive immune system CRISPR can be easily programmed to bind or cleave specific DNA sequence using a short RNA guide. Cas9 is enabling the generatio...
      Speaker: Feng Zhang, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      79
      AUG 20, 2014 | 2:15 PM
      Identifying transcriptional regulators of human embryonic development via expression variability
      Identifying transcriptional regulators of human embryonic development...
      Understanding how genes coordinate their expression across cells in a growing embryo can provide insights into the transcriptional programs that control development. Intercellular variability...
      Speaker: Jessica C. Mar, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      12
    MAR 19, 2015 | 9:00 AM
    Keynote - Impulsivity and Compulsivity: Neural Substrates and Neuropsychiatric Implications
    Keynote - Impulsivity and Compulsivity: Neural Substrates and...
    Impulsivity can be defined as the tendency to act prematurely without foresight. Behavioural and neurobiological analysis of this construct, based on evidence from both animal and human studi...
    Speaker: Trevor Robbins, CBE FRS FMedSci FBPsS
    Presented at: Neuroscience Virtual Event Series 2015
    12
    MAR 18, 2015 | 3:00 PM
    The Human Connectome Project
    The Human Connectome Project
    Recent advances in noninvasive neuroimaging have set the stage for the systematic exploration of human brain circuits in health and disease. The Human Connectome Project (HCP) is systematical...
    Speaker: David Van Essen, PhD
    Presented at: Neuroscience Virtual Event Series 2015
    10
    MAR 18, 2015 | 12:00 PM
    Keynote - Psychosis as a Learning and Memory Disorder
    Keynote - Psychosis as a Learning and Memory Disorder
    The hippocampal formation is one of the most extensively studied regions of the brain, with well described anatomy and basic physiology; moreover, aspects of human memory mediated by hippocam...
    Speaker: Carol Tamminga, MD
    Presented at: Neuroscience Virtual Event Series 2015
    10
    MAR 18, 2015 | 9:00 AM
    Special Lecturer - DREADD2.0: an Enhanced Chemogenetic Toolkit
    Special Lecturer - DREADD2.0: an Enhanced Chemogenetic Toolkit
    The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative has the ambitious goal of elucidating how neuronal ensembles interactively encode higher brain processes....
    Speaker: Bryan L. Roth, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2015
    14
    MAR 18, 2015 | 7:30 AM
    Special Lecturer - Circuits of Reward/Motivation and Decisions: Linking Connectivity to Function and Disease
    Special Lecturer - Circuits of Reward/Motivation and Decisions:...
    The dorsal anterior cingulate cortex (dACC), orbitofrontal cortex (OFC), ventrolateral and ventromedial prefrontal cortex (vlPFC, vmPFC) and their connections with the basal ganglia play a ce...
    Speaker: Suzanne Haber, PhD
    Presented at: Neuroscience Virtual Event Series 2015
    14
     
     
  • MAR 10, 2015 | 9:00 AM
    Newly Updated Guidelines for the Diagnosis of Multiple Myeloma
    Newly Updated Guidelines for the Diagnosis of Multiple Myeloma
    DATE: Tuesday, March 10, 2015 TIME: 09:00 PST, 11:00 CST, 12:00 EST, 16:00 GMTThe International Myeloma Working Group (IMWG) has issued updated criteria for the diagnosis of multiple...
    Speaker: Ola Landgren, M.D., Ph.D.
    Sponsored By: Binding Site, Binding Site
    17 7
    FEB 19, 2015 | 8:00 AM
    Presenting a complete workflow - from start to finish!
    Presenting a complete workflow - from start to finish!
    For more on Gene Editing watch “Webinar: Improve CRISPR-Cas9 experiments with rationally designed guide RNAs” The CRISPR-Cas9 system is being widely used for genome engineering...
    Speaker: Emily Anderson, Ph.D.
    Sponsored By: Dharmacon, Dharmacon
    34 1
    FEB 04, 2015 | 1:30 PM
    C.E. CREDITS
    The Surgeons Toolbox: outcomes are only as good as the contents of the box
    The Surgeons Toolbox: outcomes are only as good as the contents...
    The field of surgical research has been growing rapidly with the development of new surgical and disease models. An extremely important and often overlooked aspect of creating these models is...
    Speaker: Szczepan Baran, VMD, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    4
    FEB 04, 2015 | 7:30 AM
    C.E. CREDITS
    Normal behavior of rodents: understand it, then respect it
    Normal behavior of rodents: understand it, then respect it
    During my presentation, we will discuss:- Normal patterns of behavior (repertoire): social, food intake, territorial, agonistic, anti-predation, sleep and rest, play behavior, grooming, sex...
    Speaker: Marina Snitcofsky, DVM, MSc, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    7
    JAN 26, 2015 | 8:00 AM
    How stem cells speak with immune cells
    How stem cells speak with immune cells
    Advances in stem cell biology have raised great expectations that diseases of the central nervous system may be ameliorated by the development of non-haematopoietic stem cell medicines. Yet,...
    Speaker: Stefano Pluchino, MD, PhD
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    19 2
     
     
  • JAN 21, 2015 | 10:00 PM
    NGS-Quality Sample Preparation with Covaris Adaptive Focused Acoustics (AFAâ„¢)
    NGS-Quality Sample Preparation with Covaris Adaptive Focused Acoustics...
     In this presentation we will illustrate the advantages of AFA technology in clinically significant applications (NGS, FFPE, ChIP) and will demonstrate the flexibility of Covaris AFA in deliv...
    Speaker: Hamid Khoja Ph.D.
    Sponsored By: Covaris, Inc., Covaris, Inc.
    8
    JAN 09, 2015 | 5:30 AM
    Optimizing Workflows in Flow Cytometry
    Optimizing Workflows in Flow Cytometry
      In this webinar, the presenter will discuss:      An Introduction to EPFL’s Core Facility and its role in furthering flow cytometry research   &nb...
    Speaker: Loïc Tauzin
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    13
    OCT 30, 2014 | 3:00 PM
    Clinical Shotgun Proteomics in Cancer Biomarker and Drug Target Research/Discovery
    Clinical Shotgun Proteomics in Cancer Biomarker and Drug Target...
    Mass spectrometry (MS)-based profiling of clinical specimens has been increasingly used in cancer research to characterize changes in protein expression between tumor and healthy tissue or be...
    Speaker: Josip Blonder, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    30
    OCT 30, 2014 | 10:30 AM
    Development of molecularly targeted imaging agents and identification of novel targets in cancer
    Development of molecularly targeted imaging agents and identification...
    The era of omics has ushered in the hope for personalized medicine. Proteomic and genomic strategies that allow unbiased identification of genes and proteins and their post-transcriptional a...
    Speaker: Kimberly Kelly , PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    16
    OCT 30, 2014 | 9:00 AM
    A head-to-head comparison of whole blood derived samples (cfDNA vs CTC DNA) for cancer research using next-generation sequencing
    A head-to-head comparison of whole blood derived samples (cfDNA...
    Both cell free DNA (cfDNA) and circulating tumor cells (CTC) represent important possible templates for mutation analysis of clinical samples. Each template has different theoretical advantag...
    Speaker: Paul W. Dempsey, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    0
     
     
  • OCT 29, 2014 | 3:00 PM
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
    Speaker: Michael J Mann, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    67
    OCT 29, 2014 | 9:00 AM
    Reading and disrupting the histone code with chemical agents: making new tools to understand epigenetic methylation pathways in stem-like cancers
    Reading and disrupting the histone code with chemical agents:...
    Post-translational methylations play central roles in epigenetic gene regulation pathways that are central to stem cell regulation. Lysine methylations are turn-on switches for hundreds of di...
    Speaker: Fraser Hof, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    7
    OCT 29, 2014 | 7:30 AM
    Antibody-based Proteomics: Fast-Tracking Molecular Diagnostics and Target Discovery in Oncology
    Antibody-based Proteomics: Fast-Tracking Molecular Diagnostics...
    The effective implementation of personalised cancer therapeutic regimens depends on the successful identification and translation of informative biomarkers to aid clinical decision-making. An...
    Speaker: Darran O'Connor, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    6
    SEP 24, 2014 | 2:00 PM
    Development and Applications of CRISPR-Cas9 for Genome Editing
    Development and Applications of CRISPR-Cas9 for Genome Editing
    The RNA-guided nuclease Cas9 from the microbial CRISPR adaptive immune system has emerged as an exciting tool for precise genome editing in eukaryotic cells. This presentation will discuss th...
    Speaker: Feng Zhang, Ph.D.
    Presented at: Advances in Drug Discovery and Development
    39
    SEP 24, 2014 | 11:00 AM
    Drug Repositioning in the Era of Personalized Medicine
    Drug Repositioning in the Era of Personalized Medicine
    This presentation will focus on NuMediis general approach towards the discovery of new therapeutic uses for existing drugs. While the business models for repurposing marketed drugs versus rep...
    Speaker: Craig Webb, Ph.D.
    Presented at: Advances in Drug Discovery and Development
    32
     
     
  • SEP 24, 2014 | 11:00 AM
    Structure based Drug Design for G-protein coupled receptors using the StaR(r) technology
    Structure based Drug Design for G-protein coupled receptors using...
    Heptares Therapeutics is a structure based drug discovery and development company which uses it StaR technology to enable X-ray structures, fragment screening and other biophysical techniques...
    Speaker: Fiona Marshall, PhD
    Presented at: Advances in Drug Discovery and Development
    10
    SEP 24, 2014 | 8:00 AM
    Role of Academic Institutions in Target Selection
    Role of Academic Institutions in Target Selection
    Target selection is arguably the most important decision in all drug discovery and development activities. No amount of great science can overcome the selection of the wrong target. The rapid...
    Speaker: Michael A. Foley, Ph.D.
    Presented at: Advances in Drug Discovery and Development
    32
    AUG 21, 2014 | 6:45 AM
    Development and Applications of CRISPR-Cas9 for Genome Editing
    Development and Applications of CRISPR-Cas9 for Genome Editing
    The Cas9 endonuclease from the microbial adaptive immune system CRISPR can be easily programmed to bind or cleave specific DNA sequence using a short RNA guide. Cas9 is enabling the generatio...
    Speaker: Feng Zhang, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    79
    AUG 20, 2014 | 2:15 PM
    Identifying transcriptional regulators of human embryonic development via expression variability
    Identifying transcriptional regulators of human embryonic development...
    Understanding how genes coordinate their expression across cells in a growing embryo can provide insights into the transcriptional programs that control development. Intercellular variability...
    Speaker: Jessica C. Mar, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
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