Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
Advances in sequencing technology and increasing recognition of the importance of our microbial world have led to unprecedented discoveries in recent years with respect to the human microbiom...
The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
Managing microbial contaminants is critical during the manufacturing of biologics, food and beverage to ensure that products meet the high quality product standard as well as staying complian...
Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
DATE: August 20, 2015TIME: 8:00am PDT, 11:00am EDT, 4:00pm BSTLight Sheet Microscopy for 3D live fluorescent imaging at high spatiotemporal resolution Dr Bi-Chang Chen will discuss his ...
Date: Wednesday, June 24th, 2015 Time: 09:00AM PDT, 12:00PM EDT, 4:00PM GMT Solaris™ is a new open-air fluorescence imaging system developed by PerkinElmer, enabling translational in vivo pre...
DATE: June 17th, 2015TIME: 8am Pacific time, 11am Eastern timeSpatial heterogeneity of tumors has been identified within and between metastatic lesions and can be visualized wit...
Consistent accuracy in reporting quantitative viral load results is critically important to patients, their physicians and to the clinical laboratory. In clinical practice, quantitative viral...
Matching the mutational profile of a patient's tumor with appropriate targeted agents is a goal of personalized medicine in oncology. The number of FDA-approved targeted therapies, as well as...
Sign up here to watch this Webinar On DemandCytotoxicity remains one of the major causes of drug withdrawal and there is an urgent need for reliable and time-saving assay workflows. Cells exp...
Asthma is heritable, influenced by the environment, and is modified by in utero exposures and aging; all of these features are also common to epigenetic regulation. Furthermore, genetic varia...
I will discuss the use of genomic technologies - mostly ultrahigh-throughput DNA sequencing - to study normal human biology and to determine what goes wrong when we have disease. First I wil...
Long noncoding RNAs (lncRNAs) are increasingly recognized as having key regulatory roles in development and disease. However, these regulatory molecules often have short half lives and are ex...
The Allen Institute for Brain Science provides several brain atlases that are freely available to the public at www.brain-map.org. A common use for these atlases is to study expression patter...
Next-generation sequencing technology allows us to peer inside the cell in exquisite detail, revealing new insights into biology, evolution, and disease that would have been impossible to dis...
Cancers exhibit abnormal molecular signatures associated with disease initiation and progression. Molecular signatures could improve cancer screening, detection, drug development and selectio...
Please click here to watch this webinar On DemandsiRNA-mediated silencing of gene expression has revolutionized the study of biology by enabling rapid and unbiased loss-of-function studies to...
Centrifugal elutriation is a mature technology that has been used for purification of cell subsets such as monocytes based upon cell density and size, without the need for labeling. The techn...
Date: Tuesday, April 7th, 2015Time: 8:30AM PST, 11:30AM EST, 5:30PM CETThe development of new medicines for Diabetes Type 2 complications has proven to be challenging due to the use of cell...
The NIH BRAIN initiative, informed by the report from the scientific community (BRAIN 2025) is underway. The major funded efforts at this time fit into 3 main categories; 1) defining the comp...
DARPA’s investments aim to leverage brain-function research to alleviate the burden of illness and injury and provide novel, neurotechnology-based capabilities for military personnel an...
Behaviors are motivated by two emotional valences: Seeking pleasure and avoiding pain. The ability to select appropriate behavioral responses to environmental stimuli, such as avoiding a pred...
There is growing interest internationally in elucidating the clinical and biological profile of those at high genetic risk to bipolar disorder (BD) so as to enable the development of targeted...
Since the discovery and maturing of in vitro techniques that characterized neurotransmitter receptor systems in animal and human brain and subsequent development of in vitro and in vivo autor...
Advances in sequencing technology and increasing recognition of the importance of our microbial world have led to unprecedented discoveries in recent years with respect to the human microbiom...
The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
Managing microbial contaminants is critical during the manufacturing of biologics, food and beverage to ensure that products meet the high quality product standard as well as staying complian...
Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
DATE: August 20, 2015TIME: 8:00am PDT, 11:00am EDT, 4:00pm BSTLight Sheet Microscopy for 3D live fluorescent imaging at high spatiotemporal resolution Dr Bi-Chang Chen will discuss his ...
Date: Wednesday, June 24th, 2015 Time: 09:00AM PDT, 12:00PM EDT, 4:00PM GMT Solaris™ is a new open-air fluorescence imaging system developed by PerkinElmer, enabling translational in vivo pre...
DATE: June 17th, 2015TIME: 8am Pacific time, 11am Eastern timeSpatial heterogeneity of tumors has been identified within and between metastatic lesions and can be visualized wit...
Consistent accuracy in reporting quantitative viral load results is critically important to patients, their physicians and to the clinical laboratory. In clinical practice, quantitative viral...
Matching the mutational profile of a patient's tumor with appropriate targeted agents is a goal of personalized medicine in oncology. The number of FDA-approved targeted therapies, as well as...
Sign up here to watch this Webinar On DemandCytotoxicity remains one of the major causes of drug withdrawal and there is an urgent need for reliable and time-saving assay workflows. Cells exp...
Asthma is heritable, influenced by the environment, and is modified by in utero exposures and aging; all of these features are also common to epigenetic regulation. Furthermore, genetic varia...
I will discuss the use of genomic technologies - mostly ultrahigh-throughput DNA sequencing - to study normal human biology and to determine what goes wrong when we have disease. First I wil...
Long noncoding RNAs (lncRNAs) are increasingly recognized as having key regulatory roles in development and disease. However, these regulatory molecules often have short half lives and are ex...
The Allen Institute for Brain Science provides several brain atlases that are freely available to the public at www.brain-map.org. A common use for these atlases is to study expression patter...
Next-generation sequencing technology allows us to peer inside the cell in exquisite detail, revealing new insights into biology, evolution, and disease that would have been impossible to dis...
Cancers exhibit abnormal molecular signatures associated with disease initiation and progression. Molecular signatures could improve cancer screening, detection, drug development and selectio...
Please click here to watch this webinar On DemandsiRNA-mediated silencing of gene expression has revolutionized the study of biology by enabling rapid and unbiased loss-of-function studies to...
Centrifugal elutriation is a mature technology that has been used for purification of cell subsets such as monocytes based upon cell density and size, without the need for labeling. The techn...
Date: Tuesday, April 7th, 2015Time: 8:30AM PST, 11:30AM EST, 5:30PM CETThe development of new medicines for Diabetes Type 2 complications has proven to be challenging due to the use of cell...
The NIH BRAIN initiative, informed by the report from the scientific community (BRAIN 2025) is underway. The major funded efforts at this time fit into 3 main categories; 1) defining the comp...
DARPA’s investments aim to leverage brain-function research to alleviate the burden of illness and injury and provide novel, neurotechnology-based capabilities for military personnel an...
Behaviors are motivated by two emotional valences: Seeking pleasure and avoiding pain. The ability to select appropriate behavioral responses to environmental stimuli, such as avoiding a pred...
There is growing interest internationally in elucidating the clinical and biological profile of those at high genetic risk to bipolar disorder (BD) so as to enable the development of targeted...
Since the discovery and maturing of in vitro techniques that characterized neurotransmitter receptor systems in animal and human brain and subsequent development of in vitro and in vivo autor...
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