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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
OCT 03, 2019 | 12:00 PM
CRISPR based gene editing has proven to be an incredibly powerful tool for studying functions of individual proteins, understanding the role of multi-gene pathways, and even knocking out prot...
SEP 27, 2019 | 9:00 AM
DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
SEP 25, 2019 | 8:00 AM
DATE: September 25, 2019TIME: 8:00am PT, 11:00am ET This talk will focus on strategies for optimizing expression levels of membrane proteins using the Gibco™ Expi293™ and ExpiCHO™ Expres...
SEP 12, 2019 | 10:30 AM
The emergence and spread of antimicrobial-resistant (AMR) bacteria and resistance mechanisms pose a serious challenge to laboratories in both hospital clinical microbiology and public health...
SEP 10, 2019 | 3:00 PM
DATE: September 10, 2019 TIME: 3:00pm CEST, 06:00am PT, 09:00am ET The assessment of cell health and cellular responses after experimental manipulation continue to be...
SEP 05, 2019 | 7:00 AM
DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
AUG 22, 2019 | 10:30 AM
DNA profiling tools to teach undergraduate students about forensics generally utilize the PV92 Alu and D1S80 VNTR markers, but are both limited in scope. In contrast, advanced profiling syste...
AUG 15, 2019 | 9:00 AM
DATE: August 15, 2019TIME: 9:00am PDT, 12:00pm EDT Radiation therapy is a critical tool for the treatment of brain tumors, however, exposure to high doses of ionizing radiation...
JUL 31, 2019 | 9:00 AM
DATE: July 31, 2019TIME: 9:00am PT, 12:00pm ET The choroid plexus, which makes up the blood-cerebrospinal fluid barrier in the central nervous system (CNS), lines the ventricle...
MAY 23, 2019 | 9:00 AM
DATE: May 23, 2019TIME: 9:00am PDT, 12:00pm EDT Although mesenchymal stem/stromal cells (MSCs) chondrogenic differentiation has been thoroughly investigated...
APR 23, 2019 | 9:00 AM
DATE: April 23, 2019TIME: 9:00am PDT, 12:00pm EDT ABSTRACT: Learning Objectives: List benefits of liquid based collection and transport systems...
APR 02, 2019 | 3:00 PM
DATE: April 2, 2019TIME: 3:00pm CEST Dans ce webinaire, Marie Piketty rappelle que depuis quelques années, plusieurs cas d'interférences provoquées par l...
MAR 28, 2019 | 12:00 PM
Whole food plant-based diets and medical cannabis have shared and continues to share similar levels of scrutiny, doubt, and stigma by the traditional medical community. One reason for the med...
FEB 27, 2019 | 12:00 PM
Surgery is the first line of treatment for Stage III melanoma. Often adjuvant therapy is administered post-surgery, which can include weeks of radiation, chemotherapy, targeted drug therapy,...
FEB 27, 2019 | 8:00 AM
DATE: February 27, 2019TIME: 8:00am PST Pluripotent stem cells (PSCs) can form any tissue or cell in the body, and are the ideal starting material to manufacture...
JAN 31, 2019 | 1:30 PM
Development of novel types of therapeutics require adaptation of traditional bioprocessing applications to include the use of primary cells, such as stem cells, fibroblasts, astrocytes and ne...
JAN 31, 2019 | 12:00 PM
As the pace of biotherapeutic approvals increases, so does the pressure on makers of new biologics to complete their development processes faster and more efficiently. The success of the drug...
