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    Drug Development

    Drug development: describes the process of developing a new drug that energetically targets a specific weakness in a cell. The process consist of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery.

    Webinars

    • FEB 05, 2019 | 9:00 AM
      Complimentary Webinar: Data Privacy and Other Clinical Data Management Challenges
      Complimentary Webinar: Data Privacy and Other Clinical Data Management...
      DATE:  February 5, 2019TIME:  9:00am PST, 12:00pm EST CloudLIMS.com is pleased to invite you to attend a complimentary webinar. The webinar focuses on the importa...
      Speaker: Marianne Henderson
      Sponsored By: CloudLIMS
      9
      JAN 31, 2019 | 1:30 PM
      Standardization of Cell Viability Assays in Primary Cells as a Prerequisite for Novel Bioprocessing Applications
      Standardization of Cell Viability Assays in Primary Cells as a...
      Development of novel types of therapeutics require adaptation of traditional bioprocessing applications to include the use of primary cells, such as stem cells, fibroblasts, astrocytes and ne...
      Speaker: Simon Kaja, PhD
      Presented at: BioProcessing Virtual Event Series 2019
      2
      JAN 31, 2019 | 12:00 PM
      From Start to Finish, Bio-Techne Solutions for Bioprocessing
      From Start to Finish, Bio-Techne Solutions for Bioprocessing
      As the pace of biotherapeutic approvals increases, so does the pressure on makers of new biologics to complete their development processes faster and more efficiently. The success of the drug...
      Speaker: Christopher Heger, PhD
      Presented at: BioProcessing Virtual Event Series 2019
      Sponsored By: ACD - A Bio-Techne Brand
      3 1
      JAN 31, 2019 | 10:30 AM
      Overcoming Limitations of Conventional Tag Systems - Strep-Tactin® XT Applications
      Overcoming Limitations of Conventional Tag Systems - Strep-Tactin®...
      The Strep-Tactin®XT:Twin-Strep-tag®-purification system enables protein purification at high yields and purity under physiological conditions. Providing the highest binding affinity a...
      Speaker: Dennis Karthaus, MS
      Presented at: BioProcessing Virtual Event Series 2019
      2
      JAN 31, 2019 | 10:30 AM
      Flow-Through Polishing and The Use of Multi-Mode Ligand Libraries to Improve Process Efficiencies
      Flow-Through Polishing and The Use of Multi-Mode Ligand Libraries...
      Multi-mode chromatography has come to prominence in recent years due to the general utility of multi-mode ligands for product capture and polishing. In particular, their application in flow-t...
      Speaker: Buzz Lobbezoo
      Presented at: BioProcessing Virtual Event Series 2019
      Sponsored By: Astrea Bioseparations
      1
      JAN 31, 2019 | 9:00 AM
      Streamlining the Biologics Development Process: From Transient to Stable Production in the ExpiCHO System
      Streamlining the Biologics Development Process: From Transient...
      The biologics development process is fraught with risks from pre-clinical studies through clinical evaluation. Prominent among these risks are changes in the critical quality attributes of th...
      Speaker: Jon Zmuda, PhD
      Presented at: BioProcessing Virtual Event Series 2019
      1
      JAN 31, 2019 | 7:30 AM
      Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based Gene Delivery for Targeted Treatment of HER2-Positive Breast Cancer in Mice by Prodrugs - A New Gene-Delivered Enzyme Prodrug
      Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based...
      Prodrugs are harmless in their native state, as they are not targeted by human enzymes. But they can be converted into highly toxic compounds (the “drug”) by viral or bacterial en...
      Speaker: A.C. Matin, PhD
      Presented at: BioProcessing Virtual Event Series 2019
      1
      JAN 31, 2019 | 6:00 AM
      Overcoming Challenges in EuCODE Cell Culture Platform Development
      Overcoming Challenges in EuCODE Cell Culture Platform Development
      Ambrx’s mammalian expression platform (EuCODE™) enables non-native amino acids (nnAAs) through an expanded genetic code to both generate novel bio-therapeutics and to optimize the...
      Speaker: Weimin Lin, PhD
      Presented at: BioProcessing Virtual Event Series 2019
      3
      JAN 29, 2019 | 9:00 AM
      Targeting prostate cancer stem cells with T cell immunotherapy
      Targeting prostate cancer stem cells with T cell immunotherapy
      DATE:    January 29. 2019TIME:    09:00am PST, 12:00pm EST In healthy tissue, a reservoir of stem cells gives rise to non-stem cells while simul...
      Speaker: Amy Codd
      Sponsored By: Thermo Fisher Scientific/Gibco
      10 2
      JAN 15, 2019 | 12:00 AM
      Flexible manufacturing strategies for cell and gene therapy products
      Flexible manufacturing strategies for cell and gene therapy products
      DATE: January 15, 2018TIME:  4:00pm SGTPThere is a clear call to automate manufacturing for cell and gene therapy products, but when should you automate? In this session, we...
      Speaker: Wenyan Leong, PhD
      Sponsored By: TERUMO BCT
      6
      DEC 10, 2018 | 10:00 PM
      Better Data, Fewer Mice: micro-CT Imaging Breathes New Life into your Lung Research
      Better Data, Fewer Mice: micro-CT Imaging Breathes New Life into...
      DATE: December 11, 2018TIME: 06:00 PSTIt’s understood and accepted that animal disease models generally offer great value for pre-clinical research and efficient drug screeni...
      Speaker: Dr. Christian Dullin , Dr. Sasha (Alexandre) Belenkov , Dr. Francesca Ruscitti
      Sponsored By: Revvity
      4 1
      DEC 06, 2018 | 8:00 AM
      Using Micro-CT Imaging for the Phenotyping and Analysis of Bone Architecture
      Using Micro-CT Imaging for the Phenotyping and Analysis of Bone...
      DATE:  December 6, 2018TIME:   11:00am EST, 5:00pm CET Introduction Micro-computed tomography (micro-CT) offers significant advantages o...
      Speaker: Rob van 't Hof, BSc, MSc, PhD
      Sponsored By: Bruker Microbiology & Diagnostics
      2
      DEC 06, 2018 | 1:00 AM
      Using Micro-CT Imaging for the Phenotyping and Analysis of Bone Architecture
      Using Micro-CT Imaging for the Phenotyping and Analysis of Bone...
      DATE:    December 6, 2018TIME:    10:00am CET, 5:00pm CST Intro Micro-computed tomography (micro-CT) offers significant advantage...
      Speaker: Rob van 't Hof, BSc, MSc, PhD
      Sponsored By: Bruker Microbiology & Diagnostics
      8
      DEC 03, 2018 | 11:00 PM
      Pluripotent stem cells: How to raise the quality of your PSC culture
      Pluripotent stem cells: How to raise the quality of your PSC culture
      DATE:    December 4, 2018TIME:    8:00am CET PSCs represent an important tool in a wide range of applications, including basic research, disease...
      Speaker: Jessica Wagener, PhD , Nadine Mellies, PhD
      Sponsored By: Eppendorf
      5
      NOV 21, 2018 | 9:00 AM
      Current Controversies in the Epidemiology, Diagnosis, and Management of Vaginal Infections
      Current Controversies in the Epidemiology, Diagnosis, and Management...
      DATE: November 21,2018TIME:  09:00am PST, 12:00pm EST Vaginal infections are a source of considerable morbidity among women. It is estimated that there are more than 10...
      Speaker: Christina Muzny, MD, MSPH, FACP
      Sponsored By: Roche Molecular Diagnostics
      8
      NOV 15, 2018 | 12:00 PM
      The Washington State Department of Health's Prescription Monitoring Program - Ensuring Safe Prescribing
      The Washington State Department of Health's Prescription Monitoring...
      Drug overdose surpassed motor vehicle accidents as the leading cause of accidental death 2006 and has remained the leading cause of accidental death at the state and national level.  Mos...
      Speaker: Gary Garrety
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2018
      1
      NOV 15, 2018 | 10:00 AM
      Applications of Brain-Model Technology
      Applications of Brain-Model Technology
      The complexity of the human brain, with thousands of neuronal types, permits the development of sophisticated behavioral repertoires, such as language, tool use, self-awareness, symbolic thou...
      Speaker: Alysson Muotri
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      4
      NOV 15, 2018 | 10:00 AM
      Multiplex fluorescence immunohistochemistry using the Ultivue InSituPlex platform on the Leica Biosystems BOND RX
      Multiplex fluorescence immunohistochemistry using the Ultivue...
      DATE:  November 15, 2018TIME:  10:00am PT, 1:00pm ET Multiplex fluorescence immunohistochemistry offers a window into the biology of human disease, enabling the ana...
      Speaker: Traci DeGeer, BS, HT (ASCP) HTL, QIHC , Alexander Klimowicz
      Sponsored By: Leica Biosystems
      6 1
      NOV 15, 2018 | 9:00 AM
      LIVE TRAINING: Routine passaging
      LIVE TRAINING: Routine passaging
      Watch how to passage feeder-free Pluripotent Stem Cells (PSCs) cultured in Essential 8 medium using EDTA. Learn the best practices to help ensure successful passage of your cells....
      Speaker: Chad MacArthur
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      5
      NOV 15, 2018 | 8:00 AM
      Precise Gene Editing of Human Pluripotent Stem Cells
      Precise Gene Editing of Human Pluripotent Stem Cells
      CRISPR ribonucleoproteins (RNPs) can generate programmable gene edits, however imprecise editing and efficient delivery to human stem cells are key challenges. Here we describe novel biochemi...
      Speaker: Kris Saha
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      11
      NOV 15, 2018 | 7:00 AM
      Use of stem-cell derived endothelial cells for disease relevant cell modeling and drug discovery
      Use of stem-cell derived endothelial cells for disease relevant...
      The use of human pluripotent stem cells (hPSCs) for in vitro disease-modeling is limited by the lack of robust and efficient protocols for the differentiation of relevant adult cell types. Pr...
      Speaker: Filip Roudnicky
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      8
      NOV 15, 2018 | 4:00 AM
      Generation and application of 3D-organoid cell culture models using human induced pluripotent stem cells (iPSCs) for drug discovery
      Generation and application of 3D-organoid cell culture models...
      Development of physiologically relevant cellular models, with strong translatability to human pathophysiology, is critical for identification and validation of novel therapeutic targets. Cell...
      Speaker: Ryan Hicks
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      10 2
      NOV 14, 2018 | 3:00 PM
      Modeling Inflammation and Fibrosis in Humans with PSC-derived Steatohepatitis Liver Organoids
      Modeling Inflammation and Fibrosis in Humans with PSC-derived...
      Neuronal migration defects, including pachygyria, are among the most severe developmental brain defects in humans. Using human genetics approaches, we recently identified bi-allelic truncatin...
      Speaker: Takanori Takebe
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      8
      NOV 14, 2018 | 9:00 AM
      Accelerating Cancer Research and Clinical Innovations Using OncoLand
      Accelerating Cancer Research and Clinical Innovations Using OncoLand
      With significant decrease in the cost of sequencing in numerous commercial as well as cancer center–driven initiatives, genomic profiling is increasingly becoming routine across multipl...
      Speaker: Bing Zhou, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
    FEB 05, 2019 | 9:00 AM
    Complimentary Webinar: Data Privacy and Other Clinical Data Management Challenges
    Complimentary Webinar: Data Privacy and Other Clinical Data Management...
    DATE:  February 5, 2019TIME:  9:00am PST, 12:00pm EST CloudLIMS.com is pleased to invite you to attend a complimentary webinar. The webinar focuses on the importa...
    Speaker: Marianne Henderson
    Sponsored By: CloudLIMS
    9
    JAN 31, 2019 | 1:30 PM
    Standardization of Cell Viability Assays in Primary Cells as a Prerequisite for Novel Bioprocessing Applications
    Standardization of Cell Viability Assays in Primary Cells as a...
    Development of novel types of therapeutics require adaptation of traditional bioprocessing applications to include the use of primary cells, such as stem cells, fibroblasts, astrocytes and ne...
    Speaker: Simon Kaja, PhD
    Presented at: BioProcessing Virtual Event Series 2019
    2
    JAN 31, 2019 | 12:00 PM
    From Start to Finish, Bio-Techne Solutions for Bioprocessing
    From Start to Finish, Bio-Techne Solutions for Bioprocessing
    As the pace of biotherapeutic approvals increases, so does the pressure on makers of new biologics to complete their development processes faster and more efficiently. The success of the drug...
    Speaker: Christopher Heger, PhD
    Presented at: BioProcessing Virtual Event Series 2019
    Sponsored By: ACD - A Bio-Techne Brand
    3 1
    JAN 31, 2019 | 10:30 AM
    Overcoming Limitations of Conventional Tag Systems - Strep-Tactin® XT Applications
    Overcoming Limitations of Conventional Tag Systems - Strep-Tactin®...
    The Strep-Tactin®XT:Twin-Strep-tag®-purification system enables protein purification at high yields and purity under physiological conditions. Providing the highest binding affinity a...
    Speaker: Dennis Karthaus, MS
    Presented at: BioProcessing Virtual Event Series 2019
    2
    JAN 31, 2019 | 10:30 AM
    Flow-Through Polishing and The Use of Multi-Mode Ligand Libraries to Improve Process Efficiencies
    Flow-Through Polishing and The Use of Multi-Mode Ligand Libraries...
    Multi-mode chromatography has come to prominence in recent years due to the general utility of multi-mode ligands for product capture and polishing. In particular, their application in flow-t...
    Speaker: Buzz Lobbezoo
    Presented at: BioProcessing Virtual Event Series 2019
    Sponsored By: Astrea Bioseparations
    1
     
     
  • JAN 31, 2019 | 9:00 AM
    Streamlining the Biologics Development Process: From Transient to Stable Production in the ExpiCHO System
    Streamlining the Biologics Development Process: From Transient...
    The biologics development process is fraught with risks from pre-clinical studies through clinical evaluation. Prominent among these risks are changes in the critical quality attributes of th...
    Speaker: Jon Zmuda, PhD
    Presented at: BioProcessing Virtual Event Series 2019
    1
    JAN 31, 2019 | 7:30 AM
    Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based Gene Delivery for Targeted Treatment of HER2-Positive Breast Cancer in Mice by Prodrugs - A New Gene-Delivered Enzyme Prodrug
    Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based...
    Prodrugs are harmless in their native state, as they are not targeted by human enzymes. But they can be converted into highly toxic compounds (the “drug”) by viral or bacterial en...
    Speaker: A.C. Matin, PhD
    Presented at: BioProcessing Virtual Event Series 2019
    1
    JAN 31, 2019 | 6:00 AM
    Overcoming Challenges in EuCODE Cell Culture Platform Development
    Overcoming Challenges in EuCODE Cell Culture Platform Development
    Ambrx’s mammalian expression platform (EuCODE™) enables non-native amino acids (nnAAs) through an expanded genetic code to both generate novel bio-therapeutics and to optimize the...
    Speaker: Weimin Lin, PhD
    Presented at: BioProcessing Virtual Event Series 2019
    3
    JAN 29, 2019 | 9:00 AM
    Targeting prostate cancer stem cells with T cell immunotherapy
    Targeting prostate cancer stem cells with T cell immunotherapy
    DATE:    January 29. 2019TIME:    09:00am PST, 12:00pm EST In healthy tissue, a reservoir of stem cells gives rise to non-stem cells while simul...
    Speaker: Amy Codd
    Sponsored By: Thermo Fisher Scientific/Gibco
    10 2
    JAN 15, 2019 | 12:00 AM
    Flexible manufacturing strategies for cell and gene therapy products
    Flexible manufacturing strategies for cell and gene therapy products
    DATE: January 15, 2018TIME:  4:00pm SGTPThere is a clear call to automate manufacturing for cell and gene therapy products, but when should you automate? In this session, we...
    Speaker: Wenyan Leong, PhD
    Sponsored By: TERUMO BCT
    6
     
     
  • DEC 10, 2018 | 10:00 PM
    Better Data, Fewer Mice: micro-CT Imaging Breathes New Life into your Lung Research
    Better Data, Fewer Mice: micro-CT Imaging Breathes New Life into...
    DATE: December 11, 2018TIME: 06:00 PSTIt’s understood and accepted that animal disease models generally offer great value for pre-clinical research and efficient drug screeni...
    Speaker: Dr. Christian Dullin , Dr. Sasha (Alexandre) Belenkov , Dr. Francesca Ruscitti
    Sponsored By: Revvity
    4 1
    DEC 06, 2018 | 8:00 AM
    Using Micro-CT Imaging for the Phenotyping and Analysis of Bone Architecture
    Using Micro-CT Imaging for the Phenotyping and Analysis of Bone...
    DATE:  December 6, 2018TIME:   11:00am EST, 5:00pm CET Introduction Micro-computed tomography (micro-CT) offers significant advantages o...
    Speaker: Rob van 't Hof, BSc, MSc, PhD
    Sponsored By: Bruker Microbiology & Diagnostics
    2
    DEC 06, 2018 | 1:00 AM
    Using Micro-CT Imaging for the Phenotyping and Analysis of Bone Architecture
    Using Micro-CT Imaging for the Phenotyping and Analysis of Bone...
    DATE:    December 6, 2018TIME:    10:00am CET, 5:00pm CST Intro Micro-computed tomography (micro-CT) offers significant advantage...
    Speaker: Rob van 't Hof, BSc, MSc, PhD
    Sponsored By: Bruker Microbiology & Diagnostics
    8
    DEC 03, 2018 | 11:00 PM
    Pluripotent stem cells: How to raise the quality of your PSC culture
    Pluripotent stem cells: How to raise the quality of your PSC culture
    DATE:    December 4, 2018TIME:    8:00am CET PSCs represent an important tool in a wide range of applications, including basic research, disease...
    Speaker: Jessica Wagener, PhD , Nadine Mellies, PhD
    Sponsored By: Eppendorf
    5
    NOV 21, 2018 | 9:00 AM
    Current Controversies in the Epidemiology, Diagnosis, and Management of Vaginal Infections
    Current Controversies in the Epidemiology, Diagnosis, and Management...
    DATE: November 21,2018TIME:  09:00am PST, 12:00pm EST Vaginal infections are a source of considerable morbidity among women. It is estimated that there are more than 10...
    Speaker: Christina Muzny, MD, MSPH, FACP
    Sponsored By: Roche Molecular Diagnostics
    8
     
     
  • NOV 15, 2018 | 12:00 PM
    The Washington State Department of Health's Prescription Monitoring Program - Ensuring Safe Prescribing
    The Washington State Department of Health's Prescription Monitoring...
    Drug overdose surpassed motor vehicle accidents as the leading cause of accidental death 2006 and has remained the leading cause of accidental death at the state and national level.  Mos...
    Speaker: Gary Garrety
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2018
    1
    NOV 15, 2018 | 10:00 AM
    Applications of Brain-Model Technology
    Applications of Brain-Model Technology
    The complexity of the human brain, with thousands of neuronal types, permits the development of sophisticated behavioral repertoires, such as language, tool use, self-awareness, symbolic thou...
    Speaker: Alysson Muotri
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    4
    NOV 15, 2018 | 10:00 AM
    Multiplex fluorescence immunohistochemistry using the Ultivue InSituPlex platform on the Leica Biosystems BOND RX
    Multiplex fluorescence immunohistochemistry using the Ultivue...
    DATE:  November 15, 2018TIME:  10:00am PT, 1:00pm ET Multiplex fluorescence immunohistochemistry offers a window into the biology of human disease, enabling the ana...
    Speaker: Traci DeGeer, BS, HT (ASCP) HTL, QIHC , Alexander Klimowicz
    Sponsored By: Leica Biosystems
    6 1
    NOV 15, 2018 | 9:00 AM
    LIVE TRAINING: Routine passaging
    LIVE TRAINING: Routine passaging
    Watch how to passage feeder-free Pluripotent Stem Cells (PSCs) cultured in Essential 8 medium using EDTA. Learn the best practices to help ensure successful passage of your cells....
    Speaker: Chad MacArthur
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    5
    NOV 15, 2018 | 8:00 AM
    Precise Gene Editing of Human Pluripotent Stem Cells
    Precise Gene Editing of Human Pluripotent Stem Cells
    CRISPR ribonucleoproteins (RNPs) can generate programmable gene edits, however imprecise editing and efficient delivery to human stem cells are key challenges. Here we describe novel biochemi...
    Speaker: Kris Saha
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    11
     
     
  • NOV 15, 2018 | 7:00 AM
    Use of stem-cell derived endothelial cells for disease relevant cell modeling and drug discovery
    Use of stem-cell derived endothelial cells for disease relevant...
    The use of human pluripotent stem cells (hPSCs) for in vitro disease-modeling is limited by the lack of robust and efficient protocols for the differentiation of relevant adult cell types. Pr...
    Speaker: Filip Roudnicky
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    8
    NOV 15, 2018 | 4:00 AM
    Generation and application of 3D-organoid cell culture models using human induced pluripotent stem cells (iPSCs) for drug discovery
    Generation and application of 3D-organoid cell culture models...
    Development of physiologically relevant cellular models, with strong translatability to human pathophysiology, is critical for identification and validation of novel therapeutic targets. Cell...
    Speaker: Ryan Hicks
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    10 2
    NOV 14, 2018 | 3:00 PM
    Modeling Inflammation and Fibrosis in Humans with PSC-derived Steatohepatitis Liver Organoids
    Modeling Inflammation and Fibrosis in Humans with PSC-derived...
    Neuronal migration defects, including pachygyria, are among the most severe developmental brain defects in humans. Using human genetics approaches, we recently identified bi-allelic truncatin...
    Speaker: Takanori Takebe
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    8
    NOV 14, 2018 | 9:00 AM
    Accelerating Cancer Research and Clinical Innovations Using OncoLand
    Accelerating Cancer Research and Clinical Innovations Using OncoLand
    With significant decrease in the cost of sequencing in numerous commercial as well as cancer center–driven initiatives, genomic profiling is increasingly becoming routine across multipl...
    Speaker: Bing Zhou, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
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