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    Drug Development

    Drug development: describes the process of developing a new drug that energetically targets a specific weakness in a cell. The process consist of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery.

    Webinars

    • NOV 13, 2018 | 9:00 AM
      Extracellular Vesicles as Diagnostic and Therapeutic Tools for Cancer
      Extracellular Vesicles as Diagnostic and Therapeutic Tools for...
      DATE:  November 13, 2018TIME:   9:00am PST, 12:00pm ESTExtracellular vesicles (EVs) are cell-secreted nanoparticles that play a pivotal role in intercellular communic...
      Speaker: Sara Busatto
      Sponsored By: Thermo Fisher Scientific/Gibco
      4
      NOV 07, 2018 | 8:00 PM
      Analysis of Surface Antigens on Exosomes
      Analysis of Surface Antigens on Exosomes
      DATE: November 7, 2018TIME: 8:00PM PSTExosomes have been shown to have significant roles in cancer including disease progression acting in the tumor micro-environment, metasta...
      Speaker: Steve McClellan BS, MT, SCYM (ASCP)CM
      Sponsored By: Thermo Fisher Scientific
      3 1
      NOV 07, 2018 | 7:00 AM
      Analysis of Surface Antigens on Exosomes
      Analysis of Surface Antigens on Exosomes
      DATE: November 7, 2018TIME: 7:00AM PDTExosomes have been shown to have significant roles in cancer including disease progression acting in the tumor micro-environment, metastasis a...
      Speaker: Steve McClellan BS, MT, SCYM (ASCP)CM
      Sponsored By: Thermo Fisher Scientific
      11 1
      NOV 06, 2018 | 12:00 AM
      Smart Cell Monitoring: Resolving the changing needs of cellular research with continuous live-cell analysis
      Smart Cell Monitoring: Resolving the changing needs of cellular...
      The last decade has seen a significant shift in the way that mammalian cells are used in biomedical science. Researchers are increasingly turning from simple, reductionist recombinant cells t...
      Speaker: Del Trezise, PhD
      Presented at: Dimension of Time: From Culture to Assay
      3
      NOV 05, 2018 | 12:00 AM
      Smart Cell Monitoring Revisited
      Smart Cell Monitoring Revisited
      Biomedical researchers are increasingly using advanced human cell models for translational biology and therapeutic discovery studies. These include patient-specific samples, cultured micro-ti...
      Speaker: Del Trezise, PhD
      Presented at: Dimension of Time: From Culture to Assay
      1
      NOV 02, 2018 | 12:00 AM
      A Neuroscientist's Guide to Live-Cell Analysis: Techniques & Benefits
      A Neuroscientist's Guide to Live-Cell Analysis: Techniques & Benefits
      Despite exciting recent developments in neuroscience, identifying novel, truly effective treatments for patients with neurological and psychiatric conditions remains highly challenging. There...
      Speaker: Susana Alcantara
      Presented at: Dimension of Time: From Culture to Assay
      3
      NOV 01, 2018 | 12:00 AM
      Real-time Live-cell Analysis for Immunologists
      Real-time Live-cell Analysis for Immunologists
      Deriving deeper biological insight & improving productivity in immune-cell biologyThe most common in vitro methods for immunologists to analyze cells of the immune system are flow cyt...
      Speaker: Del Trezise, PhD
      Presented at: Dimension of Time: From Culture to Assay
      2
      NOV 01, 2018 | 12:00 AM
      Real-time antibody internalization assays using live-cell analysis
      Real-time antibody internalization assays using live-cell analysis
      Kinetic antibody internalization assays using live-cell analysisMonoclonal antibodies (mAb) and antibody-drug conjugates (ADCs) are widely used biological therapeutics. A key property of...
      Speaker: Nicola Bevan
      Presented at: Dimension of Time: From Culture to Assay
      1
      NOV 01, 2018 | 12:00 AM
      Advanced 3D cell models for cancer biology using real time live-cell analysis
      Advanced 3D cell models for cancer biology using real time live-cell...
      Integrated protocols and live-cell analysis solutions for different 3D tumor modelsIn the search for greater clinical translation, cancer researchers are increasingly turning to more comp...
      Speaker: Kalpana Patel
      Presented at: Dimension of Time: From Culture to Assay
      2
      OCT 30, 2018 | 10:00 AM
      Post-translational Modifications and Data-Independent Acquisitions - Challenges and Opportunities
      Post-translational Modifications and Data-Independent Acquisitions...
      DATE: October 30, 2018TIME: 10:00am PT, 1:00pm ET Identification and quantification of post-translational modifications (PTM) presents a unique challenge to proteomic studies...
      Speaker: Birgit Schilling, PhD , Matthew Stokes, PhD
      Sponsored By: Cell Signaling Technology
      5
      OCT 30, 2018 | 9:00 AM
      Practical Considerations in the Design of Bottom-Up Mass Spectrometry Based Proteomics Methods
      Practical Considerations in the Design of Bottom-Up Mass Spectrometry...
      DATE: October 30, 2018TIME:  9:00AM PSTMass spectrometry-based proteomics is a rapidly growing area of research that provides useful information for many fields including basi...
      Speaker: Sandra Spencer - Ph.D. Analytical Chemistry, BS Chemistry, minor Mathematics, BS Biochemistry, minor Spanish
      3
      OCT 25, 2018 | 10:30 AM
      Trash or Treasure: Optimizing Titration Electrodes and Consumables
      Trash or Treasure: Optimizing Titration Electrodes and Consumables
      Everyone that uses titration in their lab knows how simple and fast the technique can be.  However, uncertainty around when to replace electrodes creates confusion. Reagent quality, tubi...
      Speaker: Jessica McVay , Lori Spafford
      Presented at: Analytical Chemistry Virtual Event Series 2018
      Sponsored By: Metrohm USA
      1
      OCT 25, 2018 | 9:00 AM
      Advances in Hydrogen-Deuterium Exchange Mass Spectrometry That Can Improve Studies of Biosimilars and Membrane Protein Drug Targets
      Advances in Hydrogen-Deuterium Exchange Mass Spectrometry That...
      Hydrogen-deuterium exchange mass spectrometry (HDX-MS) has developed into a powerful tool for investigating biopharmaceuticals, protein interactions, and membrane protein dynamics. Since 2010...
      Speaker: Jeffrey Hudgens, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2018
      2
      OCT 25, 2018 | 8:00 AM
      Disease modeling and cancer therapy in stem cell-derived 3D organoid systems
      Disease modeling and cancer therapy in stem cell-derived 3D organoid...
      DATE: October 25, 2018TIME:  08:00am PDT, 11:00am EDT While the significance of the microbiome is unprecedented, a thorough study to dissect the role of individual popul...
      Speaker: Devanjali Dutta, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7 1
      OCT 24, 2018 | 10:30 AM
      Chemometric Methods for Analysis of 2D 1H-13C Methyl NMR Spectra of Monoclonal Antibodies for Higher Order Structure Characterization
      Chemometric Methods for Analysis of 2D 1H-13C Methyl NMR Spectra...
      Two-dimensional (2D) 1H-13C methyl correlated NMR is increasingly being recognized as a powerful tool to characterize the higher order structure (HOS) of monoclonal antibody (mAb) therapeutic...
      Speaker: Luke Arbogast, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2018
      1
      OCT 23, 2018 | 7:00 AM
      FLIPR 1536-well application in high throughput screening
      FLIPR 1536-well application in high throughput screening
      DATE: October 23, 2018TIME: 7:00AM PDTHigh Throughput Screening for the European Lead Factory (ELF) has been performed at Pivot Park Screening Centre (PPSC). 72 HTS campaigns have...
      Speaker: Helma Van Den Hurk, PhD , Tsang Wai Lam, BSc
      Sponsored By: Molecular Devices
      4
      OCT 11, 2018 | 12:00 PM
      Lung Cancer Evolution and Immune Escape
      Lung Cancer Evolution and Immune Escape
      Lung cancer is the leading cause of cancer-related mortality worldwide. Large-scale sequencing studies have revealed the complex genomic landscape of NSCLC and genomic differences between lun...
      Speaker: Nicholas McGranahan, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 10:30 AM
      Drug Targeting for Inflammatory Breast Cancer
      Drug Targeting for Inflammatory Breast Cancer
      Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
      Speaker: Kevin Williams, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      2
      OCT 11, 2018 | 9:00 AM
      Destabilization and Degradation of MYC: More Ways Than One
      Destabilization and Degradation of MYC: More Ways Than One
      The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
      Speaker: Jason De Melo, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 7:30 AM
      Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
      Keynote Presentation: In Advanced Cancers Curative Therapies Must...
      In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
      Speaker: Krastan Blagoev, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 6:00 AM
      Revealing the Hidden Landscape of Structural Variants in Cancer Genomes
      Revealing the Hidden Landscape of Structural Variants in Cancer...
      PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
      Speaker: Jonas Korlach, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 1:30 PM
      Discovery of Biomarkers Predictive of Anticancer Drug Response in Preclinical Settings
      Discovery of Biomarkers Predictive of Anticancer Drug Response...
      Some Abstract...
      Speaker: Benjamin Haibe-Kains, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 12:00 PM
      Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
      Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
      To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...
      Speaker: Jerome Galon, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 12:00 PM
      Sample to Insight:  Everything You Need to Know About RNA Sequencing
      Sample to Insight: Everything You Need to Know About RNA Sequencing
      RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
      Speaker: Jonathan Shaffer, PhD, MBA
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
    NOV 13, 2018 | 9:00 AM
    Extracellular Vesicles as Diagnostic and Therapeutic Tools for Cancer
    Extracellular Vesicles as Diagnostic and Therapeutic Tools for...
    DATE:  November 13, 2018TIME:   9:00am PST, 12:00pm ESTExtracellular vesicles (EVs) are cell-secreted nanoparticles that play a pivotal role in intercellular communic...
    Speaker: Sara Busatto
    Sponsored By: Thermo Fisher Scientific/Gibco
    4
    NOV 07, 2018 | 8:00 PM
    Analysis of Surface Antigens on Exosomes
    Analysis of Surface Antigens on Exosomes
    DATE: November 7, 2018TIME: 8:00PM PSTExosomes have been shown to have significant roles in cancer including disease progression acting in the tumor micro-environment, metasta...
    Speaker: Steve McClellan BS, MT, SCYM (ASCP)CM
    Sponsored By: Thermo Fisher Scientific
    3 1
    NOV 07, 2018 | 7:00 AM
    Analysis of Surface Antigens on Exosomes
    Analysis of Surface Antigens on Exosomes
    DATE: November 7, 2018TIME: 7:00AM PDTExosomes have been shown to have significant roles in cancer including disease progression acting in the tumor micro-environment, metastasis a...
    Speaker: Steve McClellan BS, MT, SCYM (ASCP)CM
    Sponsored By: Thermo Fisher Scientific
    11 1
    NOV 06, 2018 | 12:00 AM
    Smart Cell Monitoring: Resolving the changing needs of cellular research with continuous live-cell analysis
    Smart Cell Monitoring: Resolving the changing needs of cellular...
    The last decade has seen a significant shift in the way that mammalian cells are used in biomedical science. Researchers are increasingly turning from simple, reductionist recombinant cells t...
    Speaker: Del Trezise, PhD
    Presented at: Dimension of Time: From Culture to Assay
    3
    NOV 05, 2018 | 12:00 AM
    Smart Cell Monitoring Revisited
    Smart Cell Monitoring Revisited
    Biomedical researchers are increasingly using advanced human cell models for translational biology and therapeutic discovery studies. These include patient-specific samples, cultured micro-ti...
    Speaker: Del Trezise, PhD
    Presented at: Dimension of Time: From Culture to Assay
    1
     
     
  • NOV 02, 2018 | 12:00 AM
    A Neuroscientist's Guide to Live-Cell Analysis: Techniques & Benefits
    A Neuroscientist's Guide to Live-Cell Analysis: Techniques & Benefits
    Despite exciting recent developments in neuroscience, identifying novel, truly effective treatments for patients with neurological and psychiatric conditions remains highly challenging. There...
    Speaker: Susana Alcantara
    Presented at: Dimension of Time: From Culture to Assay
    3
    NOV 01, 2018 | 12:00 AM
    Real-time Live-cell Analysis for Immunologists
    Real-time Live-cell Analysis for Immunologists
    Deriving deeper biological insight & improving productivity in immune-cell biologyThe most common in vitro methods for immunologists to analyze cells of the immune system are flow cyt...
    Speaker: Del Trezise, PhD
    Presented at: Dimension of Time: From Culture to Assay
    2
    NOV 01, 2018 | 12:00 AM
    Real-time antibody internalization assays using live-cell analysis
    Real-time antibody internalization assays using live-cell analysis
    Kinetic antibody internalization assays using live-cell analysisMonoclonal antibodies (mAb) and antibody-drug conjugates (ADCs) are widely used biological therapeutics. A key property of...
    Speaker: Nicola Bevan
    Presented at: Dimension of Time: From Culture to Assay
    1
    NOV 01, 2018 | 12:00 AM
    Advanced 3D cell models for cancer biology using real time live-cell analysis
    Advanced 3D cell models for cancer biology using real time live-cell...
    Integrated protocols and live-cell analysis solutions for different 3D tumor modelsIn the search for greater clinical translation, cancer researchers are increasingly turning to more comp...
    Speaker: Kalpana Patel
    Presented at: Dimension of Time: From Culture to Assay
    2
    OCT 30, 2018 | 10:00 AM
    Post-translational Modifications and Data-Independent Acquisitions - Challenges and Opportunities
    Post-translational Modifications and Data-Independent Acquisitions...
    DATE: October 30, 2018TIME: 10:00am PT, 1:00pm ET Identification and quantification of post-translational modifications (PTM) presents a unique challenge to proteomic studies...
    Speaker: Birgit Schilling, PhD , Matthew Stokes, PhD
    Sponsored By: Cell Signaling Technology
    5
     
     
  • OCT 30, 2018 | 9:00 AM
    Practical Considerations in the Design of Bottom-Up Mass Spectrometry Based Proteomics Methods
    Practical Considerations in the Design of Bottom-Up Mass Spectrometry...
    DATE: October 30, 2018TIME:  9:00AM PSTMass spectrometry-based proteomics is a rapidly growing area of research that provides useful information for many fields including basi...
    Speaker: Sandra Spencer - Ph.D. Analytical Chemistry, BS Chemistry, minor Mathematics, BS Biochemistry, minor Spanish
    3
    OCT 25, 2018 | 10:30 AM
    Trash or Treasure: Optimizing Titration Electrodes and Consumables
    Trash or Treasure: Optimizing Titration Electrodes and Consumables
    Everyone that uses titration in their lab knows how simple and fast the technique can be.  However, uncertainty around when to replace electrodes creates confusion. Reagent quality, tubi...
    Speaker: Jessica McVay , Lori Spafford
    Presented at: Analytical Chemistry Virtual Event Series 2018
    Sponsored By: Metrohm USA
    1
    OCT 25, 2018 | 9:00 AM
    Advances in Hydrogen-Deuterium Exchange Mass Spectrometry That Can Improve Studies of Biosimilars and Membrane Protein Drug Targets
    Advances in Hydrogen-Deuterium Exchange Mass Spectrometry That...
    Hydrogen-deuterium exchange mass spectrometry (HDX-MS) has developed into a powerful tool for investigating biopharmaceuticals, protein interactions, and membrane protein dynamics. Since 2010...
    Speaker: Jeffrey Hudgens, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2018
    2
    OCT 25, 2018 | 8:00 AM
    Disease modeling and cancer therapy in stem cell-derived 3D organoid systems
    Disease modeling and cancer therapy in stem cell-derived 3D organoid...
    DATE: October 25, 2018TIME:  08:00am PDT, 11:00am EDT While the significance of the microbiome is unprecedented, a thorough study to dissect the role of individual popul...
    Speaker: Devanjali Dutta, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    7 1
    OCT 24, 2018 | 10:30 AM
    Chemometric Methods for Analysis of 2D 1H-13C Methyl NMR Spectra of Monoclonal Antibodies for Higher Order Structure Characterization
    Chemometric Methods for Analysis of 2D 1H-13C Methyl NMR Spectra...
    Two-dimensional (2D) 1H-13C methyl correlated NMR is increasingly being recognized as a powerful tool to characterize the higher order structure (HOS) of monoclonal antibody (mAb) therapeutic...
    Speaker: Luke Arbogast, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2018
    1
     
     
  • OCT 23, 2018 | 7:00 AM
    FLIPR 1536-well application in high throughput screening
    FLIPR 1536-well application in high throughput screening
    DATE: October 23, 2018TIME: 7:00AM PDTHigh Throughput Screening for the European Lead Factory (ELF) has been performed at Pivot Park Screening Centre (PPSC). 72 HTS campaigns have...
    Speaker: Helma Van Den Hurk, PhD , Tsang Wai Lam, BSc
    Sponsored By: Molecular Devices
    4
    OCT 11, 2018 | 12:00 PM
    Lung Cancer Evolution and Immune Escape
    Lung Cancer Evolution and Immune Escape
    Lung cancer is the leading cause of cancer-related mortality worldwide. Large-scale sequencing studies have revealed the complex genomic landscape of NSCLC and genomic differences between lun...
    Speaker: Nicholas McGranahan, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 10:30 AM
    Drug Targeting for Inflammatory Breast Cancer
    Drug Targeting for Inflammatory Breast Cancer
    Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
    Speaker: Kevin Williams, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    2
    OCT 11, 2018 | 9:00 AM
    Destabilization and Degradation of MYC: More Ways Than One
    Destabilization and Degradation of MYC: More Ways Than One
    The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
    Speaker: Jason De Melo, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 7:30 AM
    Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
    Keynote Presentation: In Advanced Cancers Curative Therapies Must...
    In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
    Speaker: Krastan Blagoev, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
     
     
  • OCT 11, 2018 | 6:00 AM
    Revealing the Hidden Landscape of Structural Variants in Cancer Genomes
    Revealing the Hidden Landscape of Structural Variants in Cancer...
    PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
    Speaker: Jonas Korlach, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 1:30 PM
    Discovery of Biomarkers Predictive of Anticancer Drug Response in Preclinical Settings
    Discovery of Biomarkers Predictive of Anticancer Drug Response...
    Some Abstract...
    Speaker: Benjamin Haibe-Kains, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 12:00 PM
    Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
    Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
    To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...
    Speaker: Jerome Galon, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 12:00 PM
    Sample to Insight:  Everything You Need to Know About RNA Sequencing
    Sample to Insight: Everything You Need to Know About RNA Sequencing
    RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
    Speaker: Jonathan Shaffer, PhD, MBA
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
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