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    Drug Manufacturing

    Drug Manufacturing: the process of industrial-scale synthesis of pharmaceutical drugs by pharmaceutical companies. The process of drug manufacturing can be broken down into a series of unit operations, such as milling, granulation, coating, tablet pressing, and others. FDA ensures the quality of drug products by carefully monitoring drug manufacturers' compliance with its Current Good Manufacturing Practice (CGMP) regulations.

    Webinars

    • MAR 27, 2019 | 6:00 AM
      Cannabis as an Anticancer Treatment: The Scientific and Human Evidence
      Cannabis as an Anticancer Treatment: The Scientific and Human...
      The use of cannabis to treat the symptoms of cancer and associated treatments is well known, but a growing body of evidence shows how cannabis can also be used as a direct anticancer agent. I...
      Speaker: Justin Kander
      Presented at: Cannabis Sciences Virtual Event Series 2019
      4
      MAR 27, 2019 | 6:00 AM
      Automating Cannabis Testing with LIMS and Laboratory Automation
      Automating Cannabis Testing with LIMS and Laboratory Automation
      Automating Cannabis Testing with Laboratory Information Management Systems (LIMS) Software systems automate not only key aspects of laboratory testing, but provide a comprehensive data manage...
      Speaker: Christine Paszko, PhD, MT (ASCP)
      Presented at: Cannabis Sciences Virtual Event Series 2019
      2
      FEB 27, 2019 | 3:00 PM
      BASKET Trials: Biomarker Driven Drug Development
      BASKET Trials: Biomarker Driven Drug Development
      Dramatic responses observed with targeted agents in the ‘right’ genomic context have fueled large scale sequencing efforts to identify ‘effective’ treatments for a giv...
      Speaker: Shivaani Kummar, MD, FACP
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      FEB 27, 2019 | 3:00 PM
      Do You Have the Gut-on-a-Chip?
      Do You Have the Gut-on-a-Chip?
      In-vitro epithelial barrier models that are more representative of in-vivo tissues are urgently needed. Here we present extracellular matrix-supported intestinal tubules in a perfused microfl...
      Speaker: Elena Naumovska, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      FEB 27, 2019 | 3:00 PM
      Targeted Cancer Chemotherapy: Developing NextGen Antibody-Drug Conjugates
      Targeted Cancer Chemotherapy: Developing NextGen Antibody-Drug...
      In today's presentation I will give an overview to developing NextGen ADCs. We will discuss everything from the beginning stages of development to the varying ADC combination therapies av...
      Speaker: Jagath Reddy Junutula, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 3:00 PM
      Automation Meets Cell Separation: Primary Cells for Drug Discovery Assays
      Automation Meets Cell Separation: Primary Cells for Drug Discovery...
      Whether you are performing killing assays, immunophenotyping of TILs, characterizing the tumor microenvironment, or investigating immunogenicity, primary cells are essential for the discovery...
      Speaker: Lotta Raty
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: Miltenyi Biotec
      2
      FEB 27, 2019 | 1:30 PM
      Aptamers in Drug Development: From Biomarker Discovery to Targeted Drug Delivery to Small Molecule Drug Detection
      Aptamers in Drug Development: From Biomarker Discovery to Targeted...
      Small size, highly selective nature, flexible chemistry and ease of manufacturing make nucleic acid aptamers attractive for multiple applications in human diagnostics and drug discovery. &nbs...
      Speaker: Bill Jackson, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 1:30 PM
      Advances in Three-Dimensional Cell Culture in Drug Research and Discovery
      Advances in Three-Dimensional Cell Culture in Drug Research and...
      Cellular research is optimal when using physiologically-relevant cell phenotypes and genotypes of human origin. This assertion has accelerated the adoption of primary cells, stem cells, and i...
      Speaker: Richard Eglen, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      FEB 27, 2019 | 1:30 PM
      Advanced Liver Tissue Model for Improved in Vitro Prediction
      Advanced Liver Tissue Model for Improved in Vitro Prediction
      Isolated hepatocytes or their enzymes comprise the basis of most in vitro DMPK and toxicity assays used to predict human hepatic outcomes. Because hepato-specific functions are typically lost...
      Speaker: Matthew Shipton, MS
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 1:30 PM
      Comprehensive NTRK Fusion Detection, Agnostic of the Fusion Partner, for Optimal Identification of Rare Genomic Events Using TruSightTM Oncology 500
      Comprehensive NTRK Fusion Detection, Agnostic of the Fusion Partner,...
      NTRK fusions are rare but important recent biomarkers linked to response to new TRK inhibitors. Comprehensive genomic profiling on all solid tumors permits detection of rare genomic events an...
      Speaker: Phillip Febbo, MD , Maude Champagne
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: Illumina
      4
      FEB 27, 2019 | 12:00 PM
      Why Pain Control Is Good Science-The Scientific Rationale
      Why Pain Control Is Good Science-The Scientific Rationale
      Too frequently the investigator will provide “scientific” reasons to justify precluding analgesics from experimental procedures that may involve more than momentary pain, often wi...
      Speaker: Marcel Perret-Gentil, DVM, MS
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 12:00 PM
      Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint Blockade in Melanoma
      Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint...
      Surgery is the first line of treatment for Stage III melanoma. Often adjuvant therapy is administered post-surgery, which can include weeks of radiation, chemotherapy, targeted drug therapy,...
      Speaker: Sarah Warren, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: NanoString Technologies
      1
      FEB 27, 2019 | 12:00 PM
      Studies on Malignancies With a Novel Proliferation Biomarker
      Studies on Malignancies With a Novel Proliferation Biomarker
      Studies in drug development and on hematological and solid Tumors with a Thymidine Kinase 1 immunoassayThere are many tumor biomarkers but, they mostly reflect tumor mass or past growth,...
      Speaker: Martin Shaw
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 12:00 PM
      Nanostructured Molecularly Imprinted Polymers: Robust, Stable and Selective Alternatives to Antibodies
      Nanostructured Molecularly Imprinted Polymers: Robust, Stable...
      NanoMIPs, often called “plastic antibodies”, are made using a proprietary self-assembly process where the template molecule is incubated with monomers, each of which is free in so...
      Speaker: Adrian Kinkaid
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 10:30 AM
      In Vivo Surgical Models for Drug Discovery: Hidden Pitfalls and Their Avoidance
      In Vivo Surgical Models for Drug Discovery: Hidden Pitfalls and...
      Over the past 25 years surgically dependent animal models have expanded from a small, almost niche area in pharmaceutical research to an important component of most research portfolios. In t...
      Speaker: Matthew Flegal, BS, SRS
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      FEB 27, 2019 | 10:30 AM
      The Current State-of-the-Art Tissue Expression Analysis Platform for Detection & Quantification of Target & Biomarker mRNAs, Splice Variants and Mutations in Preclinical & Clinical Tissues
      The Current State-of-the-Art Tissue Expression Analysis Platform...
      Advanced Cell Diagnostics’ RNAscope products and assay services are utilized widely for tissue-based gene expression analysis in early target validation, preclinical animal efficacy and...
      Speaker: Christopher Bunker, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: Advanced Cell Diagnostics
      1
      FEB 27, 2019 | 10:30 AM
      Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics and Drug Discovery
      Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics...
      An aptamer (also known as a synthetic antibody) is a stable DNA, RNA, or peptide ligand that binds with high affinity and specificity to targets such as small molecules, peptides, proteins, b...
      Speaker: G. Thomas Caltagirone, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 10:30 AM
      Developing Precision Combination Therapies to Overcome Evolution of Therapeutic Resistance
      Developing Precision Combination Therapies to Overcome Evolution...
      Recent clinical successes in cancer genome-inspired personalized medicine have been a major breakthrough in drug discovery. However, 98% of the patients have an incomplete therapeutic respons...
      Speaker: Khyati Shah, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 9:00 AM
      Keynote Presentation: Fully Automated IHC Multiplexing: Techniques and Assay Development
      Keynote Presentation: Fully Automated IHC Multiplexing: Techniques...
      Multiplexing IHC is a technique that is increasing in demand as more and more researchers and physicians are being tasked with doing more with less. With multiplexing, you have the advantage...
      Speaker: Mark Hellewell, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: Roche Diagnostics
      1
      FEB 27, 2019 | 7:30 AM
      Keynote Presentation: Second Harmonic Generation Detection of Ras Conformational Changes and Discovery of a Novel Small-Molecule Binder
      Keynote Presentation: Second Harmonic Generation Detection of...
      Second harmonic generation (SHG) is a biophysical method that sensitively measures real-time conformational change of biomolecules attached to membranes. SHG has recently been applied to dete...
      Speaker: Frank McCormick, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 6:00 AM
      Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders Using Ingenuity Pathway Analysis Software and OmicSoft OncoLand Datasets from QIAGEN
      Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders...
      The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
      Speaker: Devendra Mistry, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: QIAGEN
      1
      FEB 27, 2019 | 6:00 AM
      Biomarkers of Aging
      Biomarkers of Aging
      Ageing is a complex process that has been observed in all biological systems at every level of organisation. Some anti-ageing interventions have demonstrated life-extending effects in model o...
      Speaker: Alex Zhavoronkov, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      FEB 27, 2019 | 6:00 AM
      The Missing Link to Improving Efficiency and Productivity in the Digital Lab
      The Missing Link to Improving Efficiency and Productivity in the...
      The Chain of Custody in our labs is the unbroken link between the objects used in your research: your people, the animal models, the cell lines, reagents, compounds; the lab instruments and d...
      Speaker: Jay Campbell
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      JAN 31, 2019 | 1:30 PM
      Standardization of Cell Viability Assays in Primary Cells as a Prerequisite for Novel Bioprocessing Applications
      Standardization of Cell Viability Assays in Primary Cells as a...
      Development of novel types of therapeutics require adaptation of traditional bioprocessing applications to include the use of primary cells, such as stem cells, fibroblasts, astrocytes and ne...
      Speaker: Simon Kaja, PhD
      Presented at: BioProcessing Virtual Event Series 2019
      2
    MAR 27, 2019 | 6:00 AM
    Cannabis as an Anticancer Treatment: The Scientific and Human Evidence
    Cannabis as an Anticancer Treatment: The Scientific and Human...
    The use of cannabis to treat the symptoms of cancer and associated treatments is well known, but a growing body of evidence shows how cannabis can also be used as a direct anticancer agent. I...
    Speaker: Justin Kander
    Presented at: Cannabis Sciences Virtual Event Series 2019
    4
    MAR 27, 2019 | 6:00 AM
    Automating Cannabis Testing with LIMS and Laboratory Automation
    Automating Cannabis Testing with LIMS and Laboratory Automation
    Automating Cannabis Testing with Laboratory Information Management Systems (LIMS) Software systems automate not only key aspects of laboratory testing, but provide a comprehensive data manage...
    Speaker: Christine Paszko, PhD, MT (ASCP)
    Presented at: Cannabis Sciences Virtual Event Series 2019
    2
    FEB 27, 2019 | 3:00 PM
    BASKET Trials: Biomarker Driven Drug Development
    BASKET Trials: Biomarker Driven Drug Development
    Dramatic responses observed with targeted agents in the ‘right’ genomic context have fueled large scale sequencing efforts to identify ‘effective’ treatments for a giv...
    Speaker: Shivaani Kummar, MD, FACP
    Presented at: Drug Discovery Virtual Event Series 2019
    2
    FEB 27, 2019 | 3:00 PM
    Do You Have the Gut-on-a-Chip?
    Do You Have the Gut-on-a-Chip?
    In-vitro epithelial barrier models that are more representative of in-vivo tissues are urgently needed. Here we present extracellular matrix-supported intestinal tubules in a perfused microfl...
    Speaker: Elena Naumovska, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    2
    FEB 27, 2019 | 3:00 PM
    Targeted Cancer Chemotherapy: Developing NextGen Antibody-Drug Conjugates
    Targeted Cancer Chemotherapy: Developing NextGen Antibody-Drug...
    In today's presentation I will give an overview to developing NextGen ADCs. We will discuss everything from the beginning stages of development to the varying ADC combination therapies av...
    Speaker: Jagath Reddy Junutula, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
     
     
  • FEB 27, 2019 | 3:00 PM
    Automation Meets Cell Separation: Primary Cells for Drug Discovery Assays
    Automation Meets Cell Separation: Primary Cells for Drug Discovery...
    Whether you are performing killing assays, immunophenotyping of TILs, characterizing the tumor microenvironment, or investigating immunogenicity, primary cells are essential for the discovery...
    Speaker: Lotta Raty
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: Miltenyi Biotec
    2
    FEB 27, 2019 | 1:30 PM
    Aptamers in Drug Development: From Biomarker Discovery to Targeted Drug Delivery to Small Molecule Drug Detection
    Aptamers in Drug Development: From Biomarker Discovery to Targeted...
    Small size, highly selective nature, flexible chemistry and ease of manufacturing make nucleic acid aptamers attractive for multiple applications in human diagnostics and drug discovery. &nbs...
    Speaker: Bill Jackson, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 1:30 PM
    Advances in Three-Dimensional Cell Culture in Drug Research and Discovery
    Advances in Three-Dimensional Cell Culture in Drug Research and...
    Cellular research is optimal when using physiologically-relevant cell phenotypes and genotypes of human origin. This assertion has accelerated the adoption of primary cells, stem cells, and i...
    Speaker: Richard Eglen, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    2
    FEB 27, 2019 | 1:30 PM
    Advanced Liver Tissue Model for Improved in Vitro Prediction
    Advanced Liver Tissue Model for Improved in Vitro Prediction
    Isolated hepatocytes or their enzymes comprise the basis of most in vitro DMPK and toxicity assays used to predict human hepatic outcomes. Because hepato-specific functions are typically lost...
    Speaker: Matthew Shipton, MS
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 1:30 PM
    Comprehensive NTRK Fusion Detection, Agnostic of the Fusion Partner, for Optimal Identification of Rare Genomic Events Using TruSightTM Oncology 500
    Comprehensive NTRK Fusion Detection, Agnostic of the Fusion Partner,...
    NTRK fusions are rare but important recent biomarkers linked to response to new TRK inhibitors. Comprehensive genomic profiling on all solid tumors permits detection of rare genomic events an...
    Speaker: Phillip Febbo, MD , Maude Champagne
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: Illumina
    4
     
     
  • FEB 27, 2019 | 12:00 PM
    Why Pain Control Is Good Science-The Scientific Rationale
    Why Pain Control Is Good Science-The Scientific Rationale
    Too frequently the investigator will provide “scientific” reasons to justify precluding analgesics from experimental procedures that may involve more than momentary pain, often wi...
    Speaker: Marcel Perret-Gentil, DVM, MS
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 12:00 PM
    Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint Blockade in Melanoma
    Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint...
    Surgery is the first line of treatment for Stage III melanoma. Often adjuvant therapy is administered post-surgery, which can include weeks of radiation, chemotherapy, targeted drug therapy,...
    Speaker: Sarah Warren, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: NanoString Technologies
    1
    FEB 27, 2019 | 12:00 PM
    Studies on Malignancies With a Novel Proliferation Biomarker
    Studies on Malignancies With a Novel Proliferation Biomarker
    Studies in drug development and on hematological and solid Tumors with a Thymidine Kinase 1 immunoassayThere are many tumor biomarkers but, they mostly reflect tumor mass or past growth,...
    Speaker: Martin Shaw
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 12:00 PM
    Nanostructured Molecularly Imprinted Polymers: Robust, Stable and Selective Alternatives to Antibodies
    Nanostructured Molecularly Imprinted Polymers: Robust, Stable...
    NanoMIPs, often called “plastic antibodies”, are made using a proprietary self-assembly process where the template molecule is incubated with monomers, each of which is free in so...
    Speaker: Adrian Kinkaid
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 10:30 AM
    In Vivo Surgical Models for Drug Discovery: Hidden Pitfalls and Their Avoidance
    In Vivo Surgical Models for Drug Discovery: Hidden Pitfalls and...
    Over the past 25 years surgically dependent animal models have expanded from a small, almost niche area in pharmaceutical research to an important component of most research portfolios. In t...
    Speaker: Matthew Flegal, BS, SRS
    Presented at: Drug Discovery Virtual Event Series 2019
    2
     
     
  • FEB 27, 2019 | 10:30 AM
    The Current State-of-the-Art Tissue Expression Analysis Platform for Detection & Quantification of Target & Biomarker mRNAs, Splice Variants and Mutations in Preclinical & Clinical Tissues
    The Current State-of-the-Art Tissue Expression Analysis Platform...
    Advanced Cell Diagnostics’ RNAscope products and assay services are utilized widely for tissue-based gene expression analysis in early target validation, preclinical animal efficacy and...
    Speaker: Christopher Bunker, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: Advanced Cell Diagnostics
    1
    FEB 27, 2019 | 10:30 AM
    Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics and Drug Discovery
    Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics...
    An aptamer (also known as a synthetic antibody) is a stable DNA, RNA, or peptide ligand that binds with high affinity and specificity to targets such as small molecules, peptides, proteins, b...
    Speaker: G. Thomas Caltagirone, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 10:30 AM
    Developing Precision Combination Therapies to Overcome Evolution of Therapeutic Resistance
    Developing Precision Combination Therapies to Overcome Evolution...
    Recent clinical successes in cancer genome-inspired personalized medicine have been a major breakthrough in drug discovery. However, 98% of the patients have an incomplete therapeutic respons...
    Speaker: Khyati Shah, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 9:00 AM
    Keynote Presentation: Fully Automated IHC Multiplexing: Techniques and Assay Development
    Keynote Presentation: Fully Automated IHC Multiplexing: Techniques...
    Multiplexing IHC is a technique that is increasing in demand as more and more researchers and physicians are being tasked with doing more with less. With multiplexing, you have the advantage...
    Speaker: Mark Hellewell, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: Roche Diagnostics
    1
    FEB 27, 2019 | 7:30 AM
    Keynote Presentation: Second Harmonic Generation Detection of Ras Conformational Changes and Discovery of a Novel Small-Molecule Binder
    Keynote Presentation: Second Harmonic Generation Detection of...
    Second harmonic generation (SHG) is a biophysical method that sensitively measures real-time conformational change of biomolecules attached to membranes. SHG has recently been applied to dete...
    Speaker: Frank McCormick, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
     
     
  • FEB 27, 2019 | 6:00 AM
    Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders Using Ingenuity Pathway Analysis Software and OmicSoft OncoLand Datasets from QIAGEN
    Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders...
    The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
    Speaker: Devendra Mistry, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: QIAGEN
    1
    FEB 27, 2019 | 6:00 AM
    Biomarkers of Aging
    Biomarkers of Aging
    Ageing is a complex process that has been observed in all biological systems at every level of organisation. Some anti-ageing interventions have demonstrated life-extending effects in model o...
    Speaker: Alex Zhavoronkov, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    2
    FEB 27, 2019 | 6:00 AM
    The Missing Link to Improving Efficiency and Productivity in the Digital Lab
    The Missing Link to Improving Efficiency and Productivity in the...
    The Chain of Custody in our labs is the unbroken link between the objects used in your research: your people, the animal models, the cell lines, reagents, compounds; the lab instruments and d...
    Speaker: Jay Campbell
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    JAN 31, 2019 | 1:30 PM
    Standardization of Cell Viability Assays in Primary Cells as a Prerequisite for Novel Bioprocessing Applications
    Standardization of Cell Viability Assays in Primary Cells as a...
    Development of novel types of therapeutics require adaptation of traditional bioprocessing applications to include the use of primary cells, such as stem cells, fibroblasts, astrocytes and ne...
    Speaker: Simon Kaja, PhD
    Presented at: BioProcessing Virtual Event Series 2019
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