An Enhancer is a small section of DNA that can be used to bind protein together in order to increase the probability that the transcription of a specific gene will develop. There are hundreds of thousands of Enhancers that can be found in Prokaryotic and Eukaryotic cells within the human genome. Enhancers are cis-regulatory elements, which regulate the transcription of nearby genes and are an essential part of genetic regulatory networks.
Nanoparticle drug delivery systems (nanoDDS) are among the most promising avenues for effective treatment of many disorders, accomplished by the targeted release of chemotherapeutics, peptide...
Diagnostic error impacts millions of US adults and children every year1,2. Failure to order an appropriate diagnostic test and incorrect interpretation of diagnostic test results are co...
Cancer immunotherapy has demonstrated promising results. However, to date, researchers have failed to overcome the complex interplay between the immune system and the immune suppressive tumor...
DATE: November 4th, 2015
TIME: 11:00am Pacific time, 2:00pm Eastern time
AMPK, a highly conserved sensor of cellular energy status, is found in all eukaryotic cells and maintains met...
Date: October 27th, 2015
TIME: 8am PDT, 11am EDT, 3pm GMT, 11pm Beijing
In recent years there have been great advances in automated microscopy and imaging for generating more predictive, ...
Multidimensional molecular characterization has led to a tsunami of cancer data. Precision Medicine assumes that new understanding and better interventions will flow from this “Big Data...
Hepatocellular carcinoma (HCC) is a significant contributor to cancer-related mortality in the United States and worldwide. Current treatments are largely ineffective: single agent and combin...
The management of prostate cancer (PCa) continues to evolve and does so at a rapid rate. Research and technological developments continue to refine our definitions and management of this comp...
The burgeoning area of molecular risk assessment (gene expression profiling and/or proteomic tests) in the diagnosis and treatment of prostate cancer is rapidly illuminating how clinicians mi...
We have been developing methods to target drugs specifically to pathologic cells, thereby avoiding collateral toxicity to healthy cells. In the case of cancer, we have exploited up-regulation...
LEARNING OBJECTIVES:1. Enhanced audience understanding regarding the controversy surrounding prostate cancer screening using the PSA blood test and use of the American Uro...
Nanotechnology, the engineering and manufacture of materials at the atomic and molecular scale, is used at BIND Therapeutics to develop novel Accurin™ nanomedicines that utilize cytotoxic age...
The process by which observations in the laboratory or the clinic are transformed into demonstrably useful interventions that tangibly improve human health is frequently termed "translation."...
Recent evidence demonstrating the importance of structural complexity in advancing compounds to the clinic points to the need for enhancing small molecule screening collections with sp3-rich ...
Consumer, Household, and Industrial (CH&I) formulations have increasingly driven towards more environmentally acceptable ingredients within water-based formulations, microbial control str...
Control of infection from methicillin resistant Staphylococcus aureus (MRSA) has been a healthcare focus for more than 50 years. One of the reasons that active surveillance testing (AST) for...
Rapid advances in sequencing technology and spectroscopy have led to new measurements of the microbiome. Labs make choices based on their environment of interest and the questions they wish t...
Asthma is heritable, influenced by the environment, and is modified by in utero exposures and aging; all of these features are also common to epigenetic regulation. Furthermore, genetic varia...
Over the past few years, evidence has been accumulating to indicate that ribosomal subunits are not simply tape-heads that decode mRNA sequences into polypeptide chains, but that they also pl...
Perhaps the greatest surprise of genetic studies of human disease is that 90% of top-scoring disease-associated loci lie outside protein-coding regions. This has increased the urgency of mapp...
The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative has the ambitious goal of elucidating how neuronal ensembles interactively encode higher brain processes....
Every cell in the body can release several types of extracellular vesicles (EVs), often called ”exosomes” or ”microvesicles”. These vesicles carry a wide array of mole...
The era of omics has ushered in the hope for personalized medicine. Proteomic and genomic strategies that allow unbiased identification of genes and proteins and their post-transcriptional a...
Human malignant glioma is a uniformly fatal disease, causing over 14,000 deaths in the US this year. Adults diagnosed with malignant brain tumors have a median survival of approximately 15 mo...
Nanoparticle drug delivery systems (nanoDDS) are among the most promising avenues for effective treatment of many disorders, accomplished by the targeted release of chemotherapeutics, peptide...
Diagnostic error impacts millions of US adults and children every year1,2. Failure to order an appropriate diagnostic test and incorrect interpretation of diagnostic test results are co...
Cancer immunotherapy has demonstrated promising results. However, to date, researchers have failed to overcome the complex interplay between the immune system and the immune suppressive tumor...
DATE: November 4th, 2015
TIME: 11:00am Pacific time, 2:00pm Eastern time
AMPK, a highly conserved sensor of cellular energy status, is found in all eukaryotic cells and maintains met...
Date: October 27th, 2015
TIME: 8am PDT, 11am EDT, 3pm GMT, 11pm Beijing
In recent years there have been great advances in automated microscopy and imaging for generating more predictive, ...
Multidimensional molecular characterization has led to a tsunami of cancer data. Precision Medicine assumes that new understanding and better interventions will flow from this “Big Data...
Hepatocellular carcinoma (HCC) is a significant contributor to cancer-related mortality in the United States and worldwide. Current treatments are largely ineffective: single agent and combin...
The management of prostate cancer (PCa) continues to evolve and does so at a rapid rate. Research and technological developments continue to refine our definitions and management of this comp...
The burgeoning area of molecular risk assessment (gene expression profiling and/or proteomic tests) in the diagnosis and treatment of prostate cancer is rapidly illuminating how clinicians mi...
We have been developing methods to target drugs specifically to pathologic cells, thereby avoiding collateral toxicity to healthy cells. In the case of cancer, we have exploited up-regulation...
LEARNING OBJECTIVES:1. Enhanced audience understanding regarding the controversy surrounding prostate cancer screening using the PSA blood test and use of the American Uro...
Nanotechnology, the engineering and manufacture of materials at the atomic and molecular scale, is used at BIND Therapeutics to develop novel Accurin™ nanomedicines that utilize cytotoxic age...
The process by which observations in the laboratory or the clinic are transformed into demonstrably useful interventions that tangibly improve human health is frequently termed "translation."...
Recent evidence demonstrating the importance of structural complexity in advancing compounds to the clinic points to the need for enhancing small molecule screening collections with sp3-rich ...
Consumer, Household, and Industrial (CH&I) formulations have increasingly driven towards more environmentally acceptable ingredients within water-based formulations, microbial control str...
Control of infection from methicillin resistant Staphylococcus aureus (MRSA) has been a healthcare focus for more than 50 years. One of the reasons that active surveillance testing (AST) for...
Rapid advances in sequencing technology and spectroscopy have led to new measurements of the microbiome. Labs make choices based on their environment of interest and the questions they wish t...
Asthma is heritable, influenced by the environment, and is modified by in utero exposures and aging; all of these features are also common to epigenetic regulation. Furthermore, genetic varia...
Over the past few years, evidence has been accumulating to indicate that ribosomal subunits are not simply tape-heads that decode mRNA sequences into polypeptide chains, but that they also pl...
Perhaps the greatest surprise of genetic studies of human disease is that 90% of top-scoring disease-associated loci lie outside protein-coding regions. This has increased the urgency of mapp...
The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative has the ambitious goal of elucidating how neuronal ensembles interactively encode higher brain processes....
Every cell in the body can release several types of extracellular vesicles (EVs), often called ”exosomes” or ”microvesicles”. These vesicles carry a wide array of mole...
The era of omics has ushered in the hope for personalized medicine. Proteomic and genomic strategies that allow unbiased identification of genes and proteins and their post-transcriptional a...
Human malignant glioma is a uniformly fatal disease, causing over 14,000 deaths in the US this year. Adults diagnosed with malignant brain tumors have a median survival of approximately 15 mo...
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