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    Gene Expression

    Gene Expression: the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as transfer RNA (tRNA) or small nuclear RNA (snRNA) genes, the product is a functional RNA. The process of gene expression is used by all known life-eukaryotes (including multicellular organisms), prokaryotes (bacteria and archaea), and utilized by viruses-to generate the macromolecular machinery for life.

    Webinars

    • MAY 08, 2019 | 9:00 AM
      Development of an Arrayed Whole Human Genome KO Library for Functional Genomics Screening, Using an Optimized Multi-sgRNA Approach
      Development of an Arrayed Whole Human Genome KO Library for Functional...
      Arrayed gene knockout (KO) libraries represent a valuable resource for performing functional genomics screening. Current generation arrayed KO libraries for the whole human genome rely on eit...
      Speaker: Kevin Holden, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      Sponsored By: Synthego
      1
      MAY 08, 2019 | 9:00 AM
      C.E. CREDITS
      Circular Synthesized CRISPR/Cas gRNAs for Functional Interrogations in Single and Multiplex Formats
      Circular Synthesized CRISPR/Cas gRNAs for Functional Interrogations...
      CRISPR/Cas gene editing has become the gold standard for individual gene perturbations as well as high-throughput functional screenings, with a rapidly increasing demand for high-quality CRIS...
      Speaker: Manuel Kaulich, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      1
      MAY 08, 2019 | 7:30 AM
      C.E. CREDITS
      Keynote Presentation: Interpreting the Zero $ Genome via Base Editing, Organoids & in Situ Omics
      Keynote Presentation: Interpreting the Zero $ Genome via Base...
      To interpret genome sequence from telomere to telomere, it is helpful end-to-end haplotypes with single-molecule epigenetics overlays, via in situ omics at sub-cellular (20 nm) resolution an...
      Speaker: George Church, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      2
      MAY 08, 2019 | 6:00 AM
      Upgrading the CRISPR Toolbox - New Strategies Sharpen the CRISPR-Cas9 Scissors Utilizing Visualization and Chromatic Accessibility
      Upgrading the CRISPR Toolbox - New Strategies Sharpen the CRISPR-Cas9...
      In this webinar, we will discuss our most recent additions to our CRISPR protein portfolio, the GFP-SpCas9 and GFP-eCas9 fusion proteins. The two GFP-Cas9 fusion proteins offer great visualiz...
      Speaker: Michelle Ding, M.S. , Yanfang Jiang, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      Sponsored By: MilliporeSigma
      1
      MAY 08, 2019 | 6:00 AM
      C.E. CREDITS
      Novel DNA Methylation in Mammals
      Novel DNA Methylation in Mammals
      Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA. Although the critical role of DNA 5-methylcytosine (5mC) in the regulation of transcription is recognize...
      Speaker: Tao Wu, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      2
      APR 17, 2019 | 9:00 AM
      You've cultured an organoid and spheroid... now what?
      You've cultured an organoid and spheroid... now what?
      DATE:  April 17, 2019TIME:  9:00am PDT...
      Speaker: Takanori Takebe
      Sponsored By: Thermo Fisher Scientific
      5
      APR 09, 2019 | 9:00 AM
      Highly Multiplexed Single-Cell Westerns for Exploring Heterogeneity in Protein Kinase C (PKC) Signaling and CRISPR Knockdown Efficiency
      Highly Multiplexed Single-Cell Westerns for Exploring Heterogeneity...
      DATE: April 9, 2019TIME: 9:00 AM PDTWe will provide a general introduction to the Single-Cell Western Technology (SCW) and then present data from 2 ongoing projects from the Col...
      Speaker: Noemi Kedei, MD , Kelly Gardner, Ph.D.
      Sponsored By: ProteinSimple
      4
      APR 03, 2019 | 9:00 AM
      How to analyze/characterize your 3D culture
      How to analyze/characterize your 3D culture
      DATE:  April 3, 2019TIME:  9:00am PDT...
      Speaker: Chris Langsdorf
      Sponsored By: Thermo Fisher Scientific
      6
      MAR 28, 2019 | 12:00 PM
      Cannabis is Personal! Learn How Your Genetics Play a Big Roll
      Cannabis is Personal! Learn How Your Genetics Play a Big Roll
      In 2018 with more and more consumers having access to legal Cannabis the interest in incorporating cannabis in to their lifestyles is becoming more and more prevalent. Len May, founder of End...
      Speaker: Len May, MSC
      Presented at: Cannabis Sciences Virtual Event Series 2019
      2
      MAR 26, 2019 | 2:00 PM
      The Role of Endosomes in Prostate Cancer
      The Role of Endosomes in Prostate Cancer
      DATE:  March 26, 2019TIME:  2:00pm PDT, 5:00pm EDT  Prostate cancer is the second most common form of cancer in males, affecting one in eight men by the time t...
      Speaker: Ian Johnson, BSc., Ph.D
      Sponsored By: Thermo Fisher Scientific/Gibco
      7
      MAR 21, 2019 | 7:00 AM
      Phenotyping the tumor micro-environment with advanced tissue-based multiplexing assays
      Phenotyping the tumor micro-environment with advanced tissue-based...
      DATE:  March 21,  2019TIME:  7:00am PDT, 10:00am EDT The benefits of multiplex immunohistochemistry assays for tissue analysis are numerous. High-level multipl...
      Speaker: Katir Patel, PhD
      Sponsored By: Ultivue
      11
      MAR 20, 2019 | 9:00 AM
      Getting started in 3D - Setting up your lab and reviewing common pitfalls of researchers new to 3D
      Getting started in 3D - Setting up your lab and reviewing common...
      DATE:  March 20, 2019TIME:  9:00am PDT...
      Speaker: Mark Kennedy, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      7
      MAR 14, 2019 | 9:00 AM
      A Gene Expression Based Screening Platform for Mouse Models of Late-Onset Alzheimer's Disease
      A Gene Expression Based Screening Platform for Mouse Models of...
      Late-onset Alzheimer’s disease (LOAD) is the most common form of dementia worldwide. To date, animal models of Alzheimer’s have focused on rare familial mutations, due to a lack o...
      Speaker: Greg Carter, PhD
      Presented at: Neuroscience Virtual Event Series 2019
      Sponsored By: NanoString Technologies
      2
      MAR 05, 2019 | 9:00 AM
      Strategies to normalize miRNA expression in serum and plasma.
      Strategies to normalize miRNA expression in serum and plasma.
      DATE:  March 5, 2019TIME:  09:00am PST, 12:00pm EST MicroRNA(miRNA) are short non-coding single stranded RNA molecules that regulate gene expression at the post tran...
      Speaker: Emily Zeringer , Harita Veereshlingam, PhD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      7
      FEB 28, 2019 | 7:00 AM
      ELISA-like Assay Formats and the Benefits of Assay Automation
      ELISA-like Assay Formats and the Benefits of Assay Automation
      DATE:    February 28, 2019TIME:    7:00 AM PST, 10:00 AM EST This presentation will cover the basic ELISA assay formats as well as ELISA-like assay f...
      Speaker: Philip Gorman, MS
      Sponsored By: Beckman Coulter Life Sciences
      9
      FEB 27, 2019 | 3:00 PM
      Targeted Cancer Chemotherapy: Developing NextGen Antibody-Drug Conjugates
      Targeted Cancer Chemotherapy: Developing NextGen Antibody-Drug...
      In today's presentation I will give an overview to developing NextGen ADCs. We will discuss everything from the beginning stages of development to the varying ADC combination therapies av...
      Speaker: Jagath Reddy Junutula, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 3:00 PM
      BASKET Trials: Biomarker Driven Drug Development
      BASKET Trials: Biomarker Driven Drug Development
      Dramatic responses observed with targeted agents in the ‘right’ genomic context have fueled large scale sequencing efforts to identify ‘effective’ treatments for a giv...
      Speaker: Shivaani Kummar, MD, FACP
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      FEB 27, 2019 | 1:30 PM
      Comprehensive NTRK Fusion Detection, Agnostic of the Fusion Partner, for Optimal Identification of Rare Genomic Events Using TruSightTM Oncology 500
      Comprehensive NTRK Fusion Detection, Agnostic of the Fusion Partner,...
      NTRK fusions are rare but important recent biomarkers linked to response to new TRK inhibitors. Comprehensive genomic profiling on all solid tumors permits detection of rare genomic events an...
      Speaker: Phillip Febbo, MD , Maude Champagne
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: Illumina
      4
      FEB 27, 2019 | 1:30 PM
      Advanced Liver Tissue Model for Improved in Vitro Prediction
      Advanced Liver Tissue Model for Improved in Vitro Prediction
      Isolated hepatocytes or their enzymes comprise the basis of most in vitro DMPK and toxicity assays used to predict human hepatic outcomes. Because hepato-specific functions are typically lost...
      Speaker: Matthew Shipton, MS
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 1:30 PM
      Advances in Three-Dimensional Cell Culture in Drug Research and Discovery
      Advances in Three-Dimensional Cell Culture in Drug Research and...
      Cellular research is optimal when using physiologically-relevant cell phenotypes and genotypes of human origin. This assertion has accelerated the adoption of primary cells, stem cells, and i...
      Speaker: Richard Eglen, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      FEB 27, 2019 | 10:30 AM
      Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics and Drug Discovery
      Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics...
      An aptamer (also known as a synthetic antibody) is a stable DNA, RNA, or peptide ligand that binds with high affinity and specificity to targets such as small molecules, peptides, proteins, b...
      Speaker: G. Thomas Caltagirone, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 10:30 AM
      The Current State-of-the-Art Tissue Expression Analysis Platform for Detection & Quantification of Target & Biomarker mRNAs, Splice Variants and Mutations in Preclinical & Clinical Tissues
      The Current State-of-the-Art Tissue Expression Analysis Platform...
      Advanced Cell Diagnostics’ RNAscope products and assay services are utilized widely for tissue-based gene expression analysis in early target validation, preclinical animal efficacy and...
      Speaker: Christopher Bunker, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: Advanced Cell Diagnostics
      1
      FEB 27, 2019 | 7:30 AM
      Keynote Presentation: Second Harmonic Generation Detection of Ras Conformational Changes and Discovery of a Novel Small-Molecule Binder
      Keynote Presentation: Second Harmonic Generation Detection of...
      Second harmonic generation (SHG) is a biophysical method that sensitively measures real-time conformational change of biomolecules attached to membranes. SHG has recently been applied to dete...
      Speaker: Frank McCormick, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 6:00 AM
      Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders Using Ingenuity Pathway Analysis Software and OmicSoft OncoLand Datasets from QIAGEN
      Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders...
      The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
      Speaker: Devendra Mistry, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: QIAGEN
      1
    MAY 08, 2019 | 9:00 AM
    Development of an Arrayed Whole Human Genome KO Library for Functional Genomics Screening, Using an Optimized Multi-sgRNA Approach
    Development of an Arrayed Whole Human Genome KO Library for Functional...
    Arrayed gene knockout (KO) libraries represent a valuable resource for performing functional genomics screening. Current generation arrayed KO libraries for the whole human genome rely on eit...
    Speaker: Kevin Holden, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    Sponsored By: Synthego
    1
    MAY 08, 2019 | 9:00 AM
    C.E. CREDITS
    Circular Synthesized CRISPR/Cas gRNAs for Functional Interrogations in Single and Multiplex Formats
    Circular Synthesized CRISPR/Cas gRNAs for Functional Interrogations...
    CRISPR/Cas gene editing has become the gold standard for individual gene perturbations as well as high-throughput functional screenings, with a rapidly increasing demand for high-quality CRIS...
    Speaker: Manuel Kaulich, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    1
    MAY 08, 2019 | 7:30 AM
    C.E. CREDITS
    Keynote Presentation: Interpreting the Zero $ Genome via Base Editing, Organoids & in Situ Omics
    Keynote Presentation: Interpreting the Zero $ Genome via Base...
    To interpret genome sequence from telomere to telomere, it is helpful end-to-end haplotypes with single-molecule epigenetics overlays, via in situ omics at sub-cellular (20 nm) resolution an...
    Speaker: George Church, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    2
    MAY 08, 2019 | 6:00 AM
    Upgrading the CRISPR Toolbox - New Strategies Sharpen the CRISPR-Cas9 Scissors Utilizing Visualization and Chromatic Accessibility
    Upgrading the CRISPR Toolbox - New Strategies Sharpen the CRISPR-Cas9...
    In this webinar, we will discuss our most recent additions to our CRISPR protein portfolio, the GFP-SpCas9 and GFP-eCas9 fusion proteins. The two GFP-Cas9 fusion proteins offer great visualiz...
    Speaker: Michelle Ding, M.S. , Yanfang Jiang, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    Sponsored By: MilliporeSigma
    1
    MAY 08, 2019 | 6:00 AM
    C.E. CREDITS
    Novel DNA Methylation in Mammals
    Novel DNA Methylation in Mammals
    Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA. Although the critical role of DNA 5-methylcytosine (5mC) in the regulation of transcription is recognize...
    Speaker: Tao Wu, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    2
     
     
  • APR 17, 2019 | 9:00 AM
    You've cultured an organoid and spheroid... now what?
    You've cultured an organoid and spheroid... now what?
    DATE:  April 17, 2019TIME:  9:00am PDT...
    Speaker: Takanori Takebe
    Sponsored By: Thermo Fisher Scientific
    5
    APR 09, 2019 | 9:00 AM
    Highly Multiplexed Single-Cell Westerns for Exploring Heterogeneity in Protein Kinase C (PKC) Signaling and CRISPR Knockdown Efficiency
    Highly Multiplexed Single-Cell Westerns for Exploring Heterogeneity...
    DATE: April 9, 2019TIME: 9:00 AM PDTWe will provide a general introduction to the Single-Cell Western Technology (SCW) and then present data from 2 ongoing projects from the Col...
    Speaker: Noemi Kedei, MD , Kelly Gardner, Ph.D.
    Sponsored By: ProteinSimple
    4
    APR 03, 2019 | 9:00 AM
    How to analyze/characterize your 3D culture
    How to analyze/characterize your 3D culture
    DATE:  April 3, 2019TIME:  9:00am PDT...
    Speaker: Chris Langsdorf
    Sponsored By: Thermo Fisher Scientific
    6
    MAR 28, 2019 | 12:00 PM
    Cannabis is Personal! Learn How Your Genetics Play a Big Roll
    Cannabis is Personal! Learn How Your Genetics Play a Big Roll
    In 2018 with more and more consumers having access to legal Cannabis the interest in incorporating cannabis in to their lifestyles is becoming more and more prevalent. Len May, founder of End...
    Speaker: Len May, MSC
    Presented at: Cannabis Sciences Virtual Event Series 2019
    2
    MAR 26, 2019 | 2:00 PM
    The Role of Endosomes in Prostate Cancer
    The Role of Endosomes in Prostate Cancer
    DATE:  March 26, 2019TIME:  2:00pm PDT, 5:00pm EDT  Prostate cancer is the second most common form of cancer in males, affecting one in eight men by the time t...
    Speaker: Ian Johnson, BSc., Ph.D
    Sponsored By: Thermo Fisher Scientific/Gibco
    7
     
     
  • MAR 21, 2019 | 7:00 AM
    Phenotyping the tumor micro-environment with advanced tissue-based multiplexing assays
    Phenotyping the tumor micro-environment with advanced tissue-based...
    DATE:  March 21,  2019TIME:  7:00am PDT, 10:00am EDT The benefits of multiplex immunohistochemistry assays for tissue analysis are numerous. High-level multipl...
    Speaker: Katir Patel, PhD
    Sponsored By: Ultivue
    11
    MAR 20, 2019 | 9:00 AM
    Getting started in 3D - Setting up your lab and reviewing common pitfalls of researchers new to 3D
    Getting started in 3D - Setting up your lab and reviewing common...
    DATE:  March 20, 2019TIME:  9:00am PDT...
    Speaker: Mark Kennedy, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    7
    MAR 14, 2019 | 9:00 AM
    A Gene Expression Based Screening Platform for Mouse Models of Late-Onset Alzheimer's Disease
    A Gene Expression Based Screening Platform for Mouse Models of...
    Late-onset Alzheimer’s disease (LOAD) is the most common form of dementia worldwide. To date, animal models of Alzheimer’s have focused on rare familial mutations, due to a lack o...
    Speaker: Greg Carter, PhD
    Presented at: Neuroscience Virtual Event Series 2019
    Sponsored By: NanoString Technologies
    2
    MAR 05, 2019 | 9:00 AM
    Strategies to normalize miRNA expression in serum and plasma.
    Strategies to normalize miRNA expression in serum and plasma.
    DATE:  March 5, 2019TIME:  09:00am PST, 12:00pm EST MicroRNA(miRNA) are short non-coding single stranded RNA molecules that regulate gene expression at the post tran...
    Speaker: Emily Zeringer , Harita Veereshlingam, PhD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    7
    FEB 28, 2019 | 7:00 AM
    ELISA-like Assay Formats and the Benefits of Assay Automation
    ELISA-like Assay Formats and the Benefits of Assay Automation
    DATE:    February 28, 2019TIME:    7:00 AM PST, 10:00 AM EST This presentation will cover the basic ELISA assay formats as well as ELISA-like assay f...
    Speaker: Philip Gorman, MS
    Sponsored By: Beckman Coulter Life Sciences
    9
     
     
  • FEB 27, 2019 | 3:00 PM
    Targeted Cancer Chemotherapy: Developing NextGen Antibody-Drug Conjugates
    Targeted Cancer Chemotherapy: Developing NextGen Antibody-Drug...
    In today's presentation I will give an overview to developing NextGen ADCs. We will discuss everything from the beginning stages of development to the varying ADC combination therapies av...
    Speaker: Jagath Reddy Junutula, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 3:00 PM
    BASKET Trials: Biomarker Driven Drug Development
    BASKET Trials: Biomarker Driven Drug Development
    Dramatic responses observed with targeted agents in the ‘right’ genomic context have fueled large scale sequencing efforts to identify ‘effective’ treatments for a giv...
    Speaker: Shivaani Kummar, MD, FACP
    Presented at: Drug Discovery Virtual Event Series 2019
    2
    FEB 27, 2019 | 1:30 PM
    Comprehensive NTRK Fusion Detection, Agnostic of the Fusion Partner, for Optimal Identification of Rare Genomic Events Using TruSightTM Oncology 500
    Comprehensive NTRK Fusion Detection, Agnostic of the Fusion Partner,...
    NTRK fusions are rare but important recent biomarkers linked to response to new TRK inhibitors. Comprehensive genomic profiling on all solid tumors permits detection of rare genomic events an...
    Speaker: Phillip Febbo, MD , Maude Champagne
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: Illumina
    4
    FEB 27, 2019 | 1:30 PM
    Advanced Liver Tissue Model for Improved in Vitro Prediction
    Advanced Liver Tissue Model for Improved in Vitro Prediction
    Isolated hepatocytes or their enzymes comprise the basis of most in vitro DMPK and toxicity assays used to predict human hepatic outcomes. Because hepato-specific functions are typically lost...
    Speaker: Matthew Shipton, MS
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 1:30 PM
    Advances in Three-Dimensional Cell Culture in Drug Research and Discovery
    Advances in Three-Dimensional Cell Culture in Drug Research and...
    Cellular research is optimal when using physiologically-relevant cell phenotypes and genotypes of human origin. This assertion has accelerated the adoption of primary cells, stem cells, and i...
    Speaker: Richard Eglen, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    2
     
     
  • FEB 27, 2019 | 10:30 AM
    Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics and Drug Discovery
    Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics...
    An aptamer (also known as a synthetic antibody) is a stable DNA, RNA, or peptide ligand that binds with high affinity and specificity to targets such as small molecules, peptides, proteins, b...
    Speaker: G. Thomas Caltagirone, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 10:30 AM
    The Current State-of-the-Art Tissue Expression Analysis Platform for Detection & Quantification of Target & Biomarker mRNAs, Splice Variants and Mutations in Preclinical & Clinical Tissues
    The Current State-of-the-Art Tissue Expression Analysis Platform...
    Advanced Cell Diagnostics’ RNAscope products and assay services are utilized widely for tissue-based gene expression analysis in early target validation, preclinical animal efficacy and...
    Speaker: Christopher Bunker, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: Advanced Cell Diagnostics
    1
    FEB 27, 2019 | 7:30 AM
    Keynote Presentation: Second Harmonic Generation Detection of Ras Conformational Changes and Discovery of a Novel Small-Molecule Binder
    Keynote Presentation: Second Harmonic Generation Detection of...
    Second harmonic generation (SHG) is a biophysical method that sensitively measures real-time conformational change of biomolecules attached to membranes. SHG has recently been applied to dete...
    Speaker: Frank McCormick, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 6:00 AM
    Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders Using Ingenuity Pathway Analysis Software and OmicSoft OncoLand Datasets from QIAGEN
    Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders...
    The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
    Speaker: Devendra Mistry, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: QIAGEN
    1
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