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    Gene Regulation

    Gene Regulation is created by using mechanisms to inhibit or induce the expression of a gene product. Regulation of a gene can include: the binding of proteins to DNA elements in order to regulation of transcription, structural changes, chemical changes, or the translation of mRNA.

    Webinars

    • OCT 22, 2019 | 9:00 AM
      Preserving Data Integrity: 21 CFR Part 11 Compliance and Osmolality as a Process Parameter
      Preserving Data Integrity: 21 CFR Part 11 Compliance and Osmolality...
      DATE: October 22, 2019 TIME: 9:00am PDT, 12:00PM EDT...
      Speaker: Angela Bazigos , Kristeena Wright, PhD , Shweta Nair
      Sponsored By: Advanced Instruments
      10 1
      OCT 17, 2019 | 10:00 AM
      Analytical and Clinical Validation Requirements for Next Generation Sequencing Laboratory-Developed Tests
      Analytical and Clinical Validation Requirements for Next Generation...
      DATE: October 17, 2019TIME: 10:00am PDTNext generation sequencing (NGS) has revolutionized molecular diagnostic testing. It is important to note that, as with many molecular diagnost...
      Speaker: Ryan S. Robetorye, M.D., Ph.D.
      Sponsored By: Thermo Fisher Scientific
      10 3
      OCT 03, 2019 | 1:30 PM
      Application of Genome Editing for Improving Banana with Disease Resistance
      Application of Genome Editing for Improving Banana with Disease...
      Banana (Musa spp.) is one of the major staple food crops grown in over 140 countries in the subtropics and tropics with annual global production of around 148 million metric, feeding about 50...
      Speaker: Leena Tripathi, PhD
      Presented at: CRISPR Virtual Event Series 2019
      1
      OCT 03, 2019 | 1:30 PM
      Re-examining the ethical & regulatory dimensions of gene editing in the wake of the "CRISPR babies" scandal
      Re-examining the ethical & regulatory dimensions of gene editing...
      Over the last decade, the policy and regulatory trajectory of genomic and reproductive technologies has been a checkered one. Approaches around the world range from constitutional and crimina...
      Speaker: Erika Kleiderman, B.Sc. , LL.B.
      Presented at: CRISPR Virtual Event Series 2019
      3
      OCT 03, 2019 | 6:00 AM
      CRISPR Regulations: Rewriting DNA and Rethinking GMOs
      CRISPR Regulations: Rewriting DNA and Rethinking GMOs
      First discovered as a genome-editing tool just seven years ago, CRISPR systems have already changed the face of basic research, allowing researchers to alter the DNA of hundreds of organisms...
      Speaker: Lea Witkowsky, PhD
      Presented at: CRISPR Virtual Event Series 2019
      5
      SEP 27, 2019 | 9:00 AM
      Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
      Investigating how Tpz-1 may be used as a novel therapeutic agent...
      DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
      Speaker: Jessica Hess
      Sponsored By: Thermo Fisher Scientific/Gibco
      5
      SEP 24, 2019 | 9:00 AM
      Validating single-cell RNA-seq data using Single-Cell Western blotting and RNAscope® technology
      Validating single-cell RNA-seq data using Single-Cell Western...
      DATE: September 24, 2019TIME: 9:00am PDTThis webinar will cover the basics of the Milo Single-Cell Western blot (SCW) and RNAScope single-molecule fluorescence RNA In situ hybridizati...
      Speaker: Brian P. Hermann, PhD
      Sponsored By: Advanced Cell Diagnostics
      5
      SEP 12, 2019 | 10:00 AM
      High Sensitivity Purity Analysis of Adeno-Associated Virus (AAV) Capsid Proteins using CE-SDS
      High Sensitivity Purity Analysis of Adeno-Associated Virus (AAV)...
      DATE: September 12, 2019TIME: 10:00am PDT, 1:00pm EDT...
      Speaker: Tingting Li, MS
      Sponsored By: SCIEX
      2
      SEP 05, 2019 | 7:00 AM
      The bread and butter method of genomics: How to improve your (q)PCR
      The bread and butter method of genomics: How to improve your (q)PCR
      DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
      Speaker: Tim Schommartz, PhD
      Sponsored By: Eppendorf
      17 1
      AUG 15, 2019 | 9:00 AM
      Understanding and ameliorating radiation-induced damage to oligodendrocytes
      Understanding and ameliorating radiation-induced damage to oligodendrocytes
      DATE: August 15, 2019TIME: 9:00am PDT, 12:00pm EDT Radiation therapy is a critical tool for the treatment of brain tumors, however, exposure to high doses of ionizing radiation...
      Speaker: Alexandra Taraboletti, PHD
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      JUL 31, 2019 | 9:00 AM
      Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
      Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
      DATE: July 31, 2019TIME: 9:00am PT, 12:00pm ET The choroid plexus, which makes up the blood-cerebrospinal fluid barrier in the central nervous system (CNS), lines the ventricle...
      Speaker: Elizabeth Delery, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7 1
      JUN 05, 2019 | 5:00 PM
      Everyday culture practice - Improving reproducibility in cell culture
      Everyday culture practice - Improving reproducibility in cell...
      DATE: June 5, 2019TIME: 8:00am PDT, 11:00am EDT, 5:00pm CEST Eukaryotic cell cultures respond to the most subtle influence. Apart from the risk of contamination, minimal chan...
      Speaker: Jessica Wagener, PhD
      Sponsored By: Eppendorf
      23 2
      MAY 23, 2019 | 9:00 AM
      Doing More with Less: Stem Cells Regulate Their Fate by Altering Their Stiffness
      Doing More with Less: Stem Cells Regulate Their Fate by Altering...
      DATE:  May 23, 2019TIME:   9:00am PDT, 12:00pm EDT Although mesenchymal stem/stromal cells (MSCs) chondrogenic differentiation has been thoroughly investigated...
      Speaker: Melika Sarem, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7
      MAY 21, 2019 | 7:00 AM
      Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function
      Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key...
      DATE: May 21, 2019TIMEL 7:00am PT, 10:00am ET Human T cells are central effectors of immunity and cancer immunotherapy. CRISPR-based functional studies in T cells could prioriti...
      Speaker: Eric Shifrut, PhD
      Sponsored By: Thermo Fisher Scientific
      10 1
      MAY 16, 2019 | 4:00 PM
      Towards Standardized Workflows - A focus on microbiome insights
      Towards Standardized Workflows - A focus on microbiome insights
      DATE: May 16, 2019TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST The emergence of NGS is revolutionizing the microbiological sciences and transforming medicine. Deep sequencing has...
      Speaker: Rita Colwell, PhD , Christiane Honisch, PhD
      Sponsored By: Eppendorf
      10 2
      MAY 15, 2019 | 7:00 AM
      How a complete set of software and validation tools for microplate readers can help GMP/GLP labs meet FDA data integrity guidelines
      How a complete set of software and validation tools for microplate...
      DATE: May 15, 2019TIME: 7:00AM PDT, 10:00AM EDT, 3:00PM BST, 4:00PM CETLaboratories operating under GMP or GLP regulations must follow guidelines set by agencies to protect scientific i...
      Speaker: Thomas Hengstl, PhD , Sally Higham
      Sponsored By: Molecular Devices
      6
      MAY 09, 2019 | 10:30 AM
      Background and Troubleshooting for RT-PCR
      Background and Troubleshooting for RT-PCR
      Real-time PCR, or quantitative qPCR, is a commonly used molecular biology lab technique to determine the actual amount of PCR product at a given cycle. For quantitative reverse transcription...
      Speaker: Gillian Browne, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      Sponsored By: MilliporeSigma
      4
      MAY 08, 2019 | 12:00 PM
      Next-Generation Transcriptome and miRNome Sequencing: Intelligent Approaches to Insightful Outcomes
      Next-Generation Transcriptome and miRNome Sequencing: Intelligent...
      Next-generation transcriptome and miRNome sequencing are routinely performed on traditional cell or tissue samples, as well as more difficult samples such as FFPE samples and biofluids. Regar...
      Speaker: Jonathan Shaffer, PhD, MBA
      Presented at: Genetics and Genomics Virtual Event Series 2019
      Sponsored By: QIAGEN
      1
      MAY 08, 2019 | 10:30 AM
      C.E. CREDITS
      Using Networks to Understand Cancer Risk
      Using Networks to Understand Cancer Risk
      One of the central tenants of biology is that our genetics—our genotype—influences the physical characteristics we manifest—our phenotype. But with more than 25,000 human ge...
      Speaker: John Quackenbush, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      2
      MAY 08, 2019 | 10:30 AM
      Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders Using Ingenuity Pathway Analysis Software and OmicSoft OncoLand Datasets from QIAGEN
      Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders...
      The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
      Speaker: Devendra Mistry, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      Sponsored By: QIAGEN
      1
      MAY 08, 2019 | 9:00 AM
      C.E. CREDITS
      Circular Synthesized CRISPR/Cas gRNAs for Functional Interrogations in Single and Multiplex Formats
      Circular Synthesized CRISPR/Cas gRNAs for Functional Interrogations...
      CRISPR/Cas gene editing has become the gold standard for individual gene perturbations as well as high-throughput functional screenings, with a rapidly increasing demand for high-quality CRIS...
      Speaker: Manuel Kaulich, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      1
      MAY 08, 2019 | 6:00 AM
      C.E. CREDITS
      Novel DNA Methylation in Mammals
      Novel DNA Methylation in Mammals
      Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA. Although the critical role of DNA 5-methylcytosine (5mC) in the regulation of transcription is recognize...
      Speaker: Tao Wu, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      2
      MAR 05, 2019 | 9:00 AM
      Strategies to normalize miRNA expression in serum and plasma.
      Strategies to normalize miRNA expression in serum and plasma.
      DATE:  March 5, 2019TIME:  09:00am PST, 12:00pm EST MicroRNA(miRNA) are short non-coding single stranded RNA molecules that regulate gene expression at the post tran...
      Speaker: Emily Zeringer , Harita Veereshlingam, PhD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      7
      FEB 27, 2019 | 6:00 AM
      Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders Using Ingenuity Pathway Analysis Software and OmicSoft OncoLand Datasets from QIAGEN
      Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders...
      The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
      Speaker: Devendra Mistry, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: QIAGEN
      1
    OCT 22, 2019 | 9:00 AM
    Preserving Data Integrity: 21 CFR Part 11 Compliance and Osmolality as a Process Parameter
    Preserving Data Integrity: 21 CFR Part 11 Compliance and Osmolality...
    DATE: October 22, 2019 TIME: 9:00am PDT, 12:00PM EDT...
    Speaker: Angela Bazigos , Kristeena Wright, PhD , Shweta Nair
    Sponsored By: Advanced Instruments
    10 1
    OCT 17, 2019 | 10:00 AM
    Analytical and Clinical Validation Requirements for Next Generation Sequencing Laboratory-Developed Tests
    Analytical and Clinical Validation Requirements for Next Generation...
    DATE: October 17, 2019TIME: 10:00am PDTNext generation sequencing (NGS) has revolutionized molecular diagnostic testing. It is important to note that, as with many molecular diagnost...
    Speaker: Ryan S. Robetorye, M.D., Ph.D.
    Sponsored By: Thermo Fisher Scientific
    10 3
    OCT 03, 2019 | 1:30 PM
    Application of Genome Editing for Improving Banana with Disease Resistance
    Application of Genome Editing for Improving Banana with Disease...
    Banana (Musa spp.) is one of the major staple food crops grown in over 140 countries in the subtropics and tropics with annual global production of around 148 million metric, feeding about 50...
    Speaker: Leena Tripathi, PhD
    Presented at: CRISPR Virtual Event Series 2019
    1
    OCT 03, 2019 | 1:30 PM
    Re-examining the ethical & regulatory dimensions of gene editing in the wake of the "CRISPR babies" scandal
    Re-examining the ethical & regulatory dimensions of gene editing...
    Over the last decade, the policy and regulatory trajectory of genomic and reproductive technologies has been a checkered one. Approaches around the world range from constitutional and crimina...
    Speaker: Erika Kleiderman, B.Sc. , LL.B.
    Presented at: CRISPR Virtual Event Series 2019
    3
    OCT 03, 2019 | 6:00 AM
    CRISPR Regulations: Rewriting DNA and Rethinking GMOs
    CRISPR Regulations: Rewriting DNA and Rethinking GMOs
    First discovered as a genome-editing tool just seven years ago, CRISPR systems have already changed the face of basic research, allowing researchers to alter the DNA of hundreds of organisms...
    Speaker: Lea Witkowsky, PhD
    Presented at: CRISPR Virtual Event Series 2019
    5
     
     
  • SEP 27, 2019 | 9:00 AM
    Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
    Investigating how Tpz-1 may be used as a novel therapeutic agent...
    DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
    Speaker: Jessica Hess
    Sponsored By: Thermo Fisher Scientific/Gibco
    5
    SEP 24, 2019 | 9:00 AM
    Validating single-cell RNA-seq data using Single-Cell Western blotting and RNAscope® technology
    Validating single-cell RNA-seq data using Single-Cell Western...
    DATE: September 24, 2019TIME: 9:00am PDTThis webinar will cover the basics of the Milo Single-Cell Western blot (SCW) and RNAScope single-molecule fluorescence RNA In situ hybridizati...
    Speaker: Brian P. Hermann, PhD
    Sponsored By: Advanced Cell Diagnostics
    5
    SEP 12, 2019 | 10:00 AM
    High Sensitivity Purity Analysis of Adeno-Associated Virus (AAV) Capsid Proteins using CE-SDS
    High Sensitivity Purity Analysis of Adeno-Associated Virus (AAV)...
    DATE: September 12, 2019TIME: 10:00am PDT, 1:00pm EDT...
    Speaker: Tingting Li, MS
    Sponsored By: SCIEX
    2
    SEP 05, 2019 | 7:00 AM
    The bread and butter method of genomics: How to improve your (q)PCR
    The bread and butter method of genomics: How to improve your (q)PCR
    DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
    Speaker: Tim Schommartz, PhD
    Sponsored By: Eppendorf
    17 1
    AUG 15, 2019 | 9:00 AM
    Understanding and ameliorating radiation-induced damage to oligodendrocytes
    Understanding and ameliorating radiation-induced damage to oligodendrocytes
    DATE: August 15, 2019TIME: 9:00am PDT, 12:00pm EDT Radiation therapy is a critical tool for the treatment of brain tumors, however, exposure to high doses of ionizing radiation...
    Speaker: Alexandra Taraboletti, PHD
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
     
     
  • JUL 31, 2019 | 9:00 AM
    Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
    Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
    DATE: July 31, 2019TIME: 9:00am PT, 12:00pm ET The choroid plexus, which makes up the blood-cerebrospinal fluid barrier in the central nervous system (CNS), lines the ventricle...
    Speaker: Elizabeth Delery, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    7 1
    JUN 05, 2019 | 5:00 PM
    Everyday culture practice - Improving reproducibility in cell culture
    Everyday culture practice - Improving reproducibility in cell...
    DATE: June 5, 2019TIME: 8:00am PDT, 11:00am EDT, 5:00pm CEST Eukaryotic cell cultures respond to the most subtle influence. Apart from the risk of contamination, minimal chan...
    Speaker: Jessica Wagener, PhD
    Sponsored By: Eppendorf
    23 2
    MAY 23, 2019 | 9:00 AM
    Doing More with Less: Stem Cells Regulate Their Fate by Altering Their Stiffness
    Doing More with Less: Stem Cells Regulate Their Fate by Altering...
    DATE:  May 23, 2019TIME:   9:00am PDT, 12:00pm EDT Although mesenchymal stem/stromal cells (MSCs) chondrogenic differentiation has been thoroughly investigated...
    Speaker: Melika Sarem, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    7
    MAY 21, 2019 | 7:00 AM
    Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function
    Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key...
    DATE: May 21, 2019TIMEL 7:00am PT, 10:00am ET Human T cells are central effectors of immunity and cancer immunotherapy. CRISPR-based functional studies in T cells could prioriti...
    Speaker: Eric Shifrut, PhD
    Sponsored By: Thermo Fisher Scientific
    10 1
    MAY 16, 2019 | 4:00 PM
    Towards Standardized Workflows - A focus on microbiome insights
    Towards Standardized Workflows - A focus on microbiome insights
    DATE: May 16, 2019TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST The emergence of NGS is revolutionizing the microbiological sciences and transforming medicine. Deep sequencing has...
    Speaker: Rita Colwell, PhD , Christiane Honisch, PhD
    Sponsored By: Eppendorf
    10 2
     
     
  • MAY 15, 2019 | 7:00 AM
    How a complete set of software and validation tools for microplate readers can help GMP/GLP labs meet FDA data integrity guidelines
    How a complete set of software and validation tools for microplate...
    DATE: May 15, 2019TIME: 7:00AM PDT, 10:00AM EDT, 3:00PM BST, 4:00PM CETLaboratories operating under GMP or GLP regulations must follow guidelines set by agencies to protect scientific i...
    Speaker: Thomas Hengstl, PhD , Sally Higham
    Sponsored By: Molecular Devices
    6
    MAY 09, 2019 | 10:30 AM
    Background and Troubleshooting for RT-PCR
    Background and Troubleshooting for RT-PCR
    Real-time PCR, or quantitative qPCR, is a commonly used molecular biology lab technique to determine the actual amount of PCR product at a given cycle. For quantitative reverse transcription...
    Speaker: Gillian Browne, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    Sponsored By: MilliporeSigma
    4
    MAY 08, 2019 | 12:00 PM
    Next-Generation Transcriptome and miRNome Sequencing: Intelligent Approaches to Insightful Outcomes
    Next-Generation Transcriptome and miRNome Sequencing: Intelligent...
    Next-generation transcriptome and miRNome sequencing are routinely performed on traditional cell or tissue samples, as well as more difficult samples such as FFPE samples and biofluids. Regar...
    Speaker: Jonathan Shaffer, PhD, MBA
    Presented at: Genetics and Genomics Virtual Event Series 2019
    Sponsored By: QIAGEN
    1
    MAY 08, 2019 | 10:30 AM
    C.E. CREDITS
    Using Networks to Understand Cancer Risk
    Using Networks to Understand Cancer Risk
    One of the central tenants of biology is that our genetics—our genotype—influences the physical characteristics we manifest—our phenotype. But with more than 25,000 human ge...
    Speaker: John Quackenbush, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    2
    MAY 08, 2019 | 10:30 AM
    Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders Using Ingenuity Pathway Analysis Software and OmicSoft OncoLand Datasets from QIAGEN
    Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders...
    The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
    Speaker: Devendra Mistry, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    Sponsored By: QIAGEN
    1
     
     
  • MAY 08, 2019 | 9:00 AM
    C.E. CREDITS
    Circular Synthesized CRISPR/Cas gRNAs for Functional Interrogations in Single and Multiplex Formats
    Circular Synthesized CRISPR/Cas gRNAs for Functional Interrogations...
    CRISPR/Cas gene editing has become the gold standard for individual gene perturbations as well as high-throughput functional screenings, with a rapidly increasing demand for high-quality CRIS...
    Speaker: Manuel Kaulich, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    1
    MAY 08, 2019 | 6:00 AM
    C.E. CREDITS
    Novel DNA Methylation in Mammals
    Novel DNA Methylation in Mammals
    Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA. Although the critical role of DNA 5-methylcytosine (5mC) in the regulation of transcription is recognize...
    Speaker: Tao Wu, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    2
    MAR 05, 2019 | 9:00 AM
    Strategies to normalize miRNA expression in serum and plasma.
    Strategies to normalize miRNA expression in serum and plasma.
    DATE:  March 5, 2019TIME:  09:00am PST, 12:00pm EST MicroRNA(miRNA) are short non-coding single stranded RNA molecules that regulate gene expression at the post tran...
    Speaker: Emily Zeringer , Harita Veereshlingam, PhD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    7
    FEB 27, 2019 | 6:00 AM
    Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders Using Ingenuity Pathway Analysis Software and OmicSoft OncoLand Datasets from QIAGEN
    Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders...
    The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
    Speaker: Devendra Mistry, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: QIAGEN
    1
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