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    Gene

    Gene: is a sequence of nucleotides in DNA or RNA that codes for a molecule that has a function. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function.

    Webinars

    • FEB 05, 2015 | 10:30 AM
      C.E. CREDITS
      Effective Workplace Training for English Language Learners
      Effective Workplace Training for English Language Learners
      Effective workplace training in a research facility is an important key in ensuring smooth operations and high standards of animal care. Today's diverse workforce offers many benefits such a...
      Speaker: Paula Clifford, MLA, RLATG, CVT
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      10
      FEB 05, 2015 | 9:00 AM
      C.E. CREDITS
      Keynote: Advances in Perioperative Care -Promoting good animal welfare and good science
      Keynote: Advances in Perioperative Care -Promoting good animal...
      Recent advances in anesthesia, monitoring, pain assessment and analgesia provide many opportunities for improving the quality of our in vivo scientific data, and promoting high standards of a...
      Speaker: Paul Flecknell, MA, VetMB, PhD, DLAS, DECVAA, DECLAM, (Hon)DACLAM, (Hon) FRCVS, Dr.hc
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      6
      FEB 05, 2015 | 7:30 AM
      C.E. CREDITS
      Fish Welfare: Stress, Pathology, Handling and Managing
      Fish Welfare: Stress, Pathology, Handling and Managing
      Fish are vertebrates but they are physiologically and psychologically different from mammals. This presentation will try to explain their differences from mammals and the different aspects t...
      Speaker: Juan Ramos, DVM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      12
      FEB 05, 2015 | 7:30 AM
      C.E. CREDITS
      Small Animal Anesthesia: A New Method to Help Control Variables
      Small Animal Anesthesia: A New Method to Help Control Variables
      An anesthesia system designed to accommodate the physiological characteristics of small animals, including rats and mice, has the potential to provide great practical value to the life scienc...
      Speaker: Andrew H Ide, BS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      12
      FEB 05, 2015 | 6:00 AM
      C.E. CREDITS
      Protect Your Research: Know Your B6 Mouse
      Protect Your Research: Know Your B6 Mouse
      Many researchers are not aware of the critical importance of genetic background of mice, including the concept of inbred substrains, and how the genetic background of substrains can impact th...
      Speaker: Brian Soper, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      8
      FEB 05, 2015 | 6:00 AM
      C.E. CREDITS
      Improving the Post-Operative Recovery of Rodents through Nutrition and Enrichment
      Improving the Post-Operative Recovery of Rodents through Nutrition...
      Laboratory animal surgical models are instrumental in biomedical research; therefore establishing healthy defined animal models is crucial to this research. Surgical procedures produce metab...
      Speaker: Jaime Lecker, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      11
      FEB 04, 2015 | 1:30 PM
      C.E. CREDITS
      The Surgeons Toolbox: outcomes are only as good as the contents of the box
      The Surgeons Toolbox: outcomes are only as good as the contents...
      The field of surgical research has been growing rapidly with the development of new surgical and disease models. An extremely important and often overlooked aspect of creating these models is...
      Speaker: Szczepan Baran, VMD, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      4
      FEB 04, 2015 | 12:00 PM
      C.E. CREDITS
      Standards and regulations for animal use in research: challenges and changes in a chilean university
      Standards and regulations for animal use in research: challenges...
      In Chile, the regulatory context regarding animal use in research is very poor. A legal framework for Animal Care and Use Committees is practically nonexistent. Also, the chilean culture play...
      Speaker: Andrea Leisewitz, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      5
      FEB 04, 2015 | 10:30 AM
      C.E. CREDITS
      Keynote: Practical Tips to Optimize Surgical Results in Rodents
      Keynote: Practical Tips to Optimize Surgical Results in Rodents
      It is the often-ignored simple tips in rodent surgery that make the difference and help minimize postoperative complications and mortality. The presenter will use his years of experience to...
      Speaker: Marcel Perret-Gentil, DVM, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      4
      FEB 04, 2015 | 9:00 AM
      C.E. CREDITS
      Keynote: Applying Principles of Biosafety in Laboratory Animal Facilities
      Keynote: Applying Principles of Biosafety in Laboratory Animal...
      Some commonly accepted principles of biosafety include the strict adherence to standard laboratory practices and techniques, the use of safety equipment such as primary barriers and personal...
      Speaker: James R Swearengen, DVM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      14
      FEB 04, 2015 | 7:30 AM
      C.E. CREDITS
      Transportation of Lab Animals - Threats from and Solutions to Animal Extremism interference
      Transportation of Lab Animals - Threats from and Solutions to...
      The transportation of laboratory animals is a critical step in obtaining the proper strain of animal that best fits the researchers needs. Animal Extremist groups have made this transportati...
      Speaker: Ted Wasky
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      4
      FEB 04, 2015 | 7:30 AM
      C.E. CREDITS
      Normal behavior of rodents: understand it, then respect it
      Normal behavior of rodents: understand it, then respect it
      During my presentation, we will discuss:- Normal patterns of behavior (repertoire): social, food intake, territorial, agonistic, anti-predation, sleep and rest, play behavior, grooming, sex...
      Speaker: Marina Snitcofsky, DVM, MSc, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      7
      FEB 04, 2015 | 6:00 AM
      C.E. CREDITS
      Training, Competency Assessment and Best Practice in Aseptic Technique
      Training, Competency Assessment and Best Practice in Aseptic Technique
      Adherence to strict aseptic technique is vital to all types of animal models requiring surgical intervention from both scientific and welfare perspectives. Training of both new and experience...
      Speaker: Angela Kerton, B.VetMed Cert LAS MRCVS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      7
      FEB 04, 2015 | 6:00 AM
      C.E. CREDITS
      PCR testing in rodent health monitoring program: where are we exactly?
      PCR testing in rodent health monitoring program: where are we...
      Soiled-bedding sentinels are not always efficient in detecting pathogens in rodent colonies. In this context, PCR-based testing can be more sensitive and is being advocated as adjunct to trad...
      Speaker: Mathias Leblanc, DVM, PhD, DES, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      33
      JAN 27, 2015 | 2:00 AM
      Catch-and-Release: Extraction and Purification of NGS-Grade DNA and RNA from FFPE Tissue Samples
      Catch-and-Release: Extraction and Purification of NGS-Grade DNA...
      Formalin Fixed, Paraffin Embedded (FFPE) tissues are rapidly being adopted for transcriptome analysis in conjunction with targeted and whole genome sequencing. Harsh formaldehyde fixation an...
      Speaker: Guillaume Durin, PhD
      Sponsored By: Covaris, Inc., Covaris, Inc.
      10
      OCT 30, 2014 | 10:30 AM
      Genomics in the Clinic: Promises and Challenges
      Genomics in the Clinic: Promises and Challenges
      Uncovering the genetic lesions underpinning cancer through genomic profiling in a clinical setting could provide insights into possible treatment options for oncologists and their patients. N...
      Speaker: John Carpten, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
      OCT 30, 2014 | 10:30 AM
      Development of molecularly targeted imaging agents and identification of novel targets in cancer
      Development of molecularly targeted imaging agents and identification...
      The era of omics has ushered in the hope for personalized medicine. Proteomic and genomic strategies that allow unbiased identification of genes and proteins and their post-transcriptional a...
      Speaker: Kimberly Kelly , PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      16
      OCT 30, 2014 | 9:00 AM
      A head-to-head comparison of whole blood derived samples (cfDNA vs CTC DNA) for cancer research using next-generation sequencing
      A head-to-head comparison of whole blood derived samples (cfDNA...
      Both cell free DNA (cfDNA) and circulating tumor cells (CTC) represent important possible templates for mutation analysis of clinical samples. Each template has different theoretical advantag...
      Speaker: Paul W. Dempsey, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      0
      OCT 30, 2014 | 7:30 AM
      Challenges in biomarker testing in non-small cell lung cancer research
      Challenges in biomarker testing in non-small cell lung cancer...
      Fusion genes play a central role in many cancer types. They have been used to classify malignancy, risk factors, disease prognosis, and companion diagnostic biomarkers for certain approved dr...
      Speaker: Nicola Normanno, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      14
      OCT 30, 2014 | 6:00 AM
      Epigenetic Dysregulation in the Pathogenesis of Myeloproliferative Neoplasms
      Epigenetic Dysregulation in the Pathogenesis of Myeloproliferative...
      When the BCR/ABL1 fusion protein was identified in chronic myelogenous leukemia and the JAK2 V617F mutation was identified in patients with other myeloproliferative neoplasms (MPNs) such as p...
      Speaker: Kristin Landis-Piwowar, PhD, MLS
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      8
      OCT 30, 2014 | 6:00 AM
      A platform for combining the results of WES and RNA-seq analysis
      A platform for combining the results of WES and RNA-seq analysis
      Cancer research is being revolutionized by targeted gene panels, whole exome sequencing (WES), whole genome sequencing (WGS), and transcriptome sequencing (RNA-Seq).Many analyses, such as...
      Speaker: Naomi Thomson
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
      OCT 29, 2014 | 3:00 PM
      Drug-tailored, efficacy-predictive and prognostic biomarker approaches for proper patient selection
      Drug-tailored, efficacy-predictive and prognostic biomarker approaches...
      Over the last decade we have witnessed tremendous advances in our understanding of the underlying molecular alterations in human cancer. This has stimulated excitement for our ability to deve...
      Speaker: Peter Blume-Jensen, MD, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      0
      OCT 29, 2014 | 3:00 PM
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
      Speaker: Michael J Mann, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      67
      OCT 29, 2014 | 1:30 PM
      PDX Tumor Models for Oncology Research and Preclinical Prediction
      PDX Tumor Models for Oncology Research and Preclinical Prediction
      Patient-derived xenograft (PDX) models can recapitulate patient tumor histopathology, mutational status, gene expression patterns, and drug response with remarkable fidelity. At The Jackson L...
      Speaker: Walter Ausserer, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      50
    FEB 05, 2015 | 10:30 AM
    C.E. CREDITS
    Effective Workplace Training for English Language Learners
    Effective Workplace Training for English Language Learners
    Effective workplace training in a research facility is an important key in ensuring smooth operations and high standards of animal care. Today's diverse workforce offers many benefits such a...
    Speaker: Paula Clifford, MLA, RLATG, CVT
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    10
    FEB 05, 2015 | 9:00 AM
    C.E. CREDITS
    Keynote: Advances in Perioperative Care -Promoting good animal welfare and good science
    Keynote: Advances in Perioperative Care -Promoting good animal...
    Recent advances in anesthesia, monitoring, pain assessment and analgesia provide many opportunities for improving the quality of our in vivo scientific data, and promoting high standards of a...
    Speaker: Paul Flecknell, MA, VetMB, PhD, DLAS, DECVAA, DECLAM, (Hon)DACLAM, (Hon) FRCVS, Dr.hc
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    6
    FEB 05, 2015 | 7:30 AM
    C.E. CREDITS
    Fish Welfare: Stress, Pathology, Handling and Managing
    Fish Welfare: Stress, Pathology, Handling and Managing
    Fish are vertebrates but they are physiologically and psychologically different from mammals. This presentation will try to explain their differences from mammals and the different aspects t...
    Speaker: Juan Ramos, DVM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    12
    FEB 05, 2015 | 7:30 AM
    C.E. CREDITS
    Small Animal Anesthesia: A New Method to Help Control Variables
    Small Animal Anesthesia: A New Method to Help Control Variables
    An anesthesia system designed to accommodate the physiological characteristics of small animals, including rats and mice, has the potential to provide great practical value to the life scienc...
    Speaker: Andrew H Ide, BS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    12
    FEB 05, 2015 | 6:00 AM
    C.E. CREDITS
    Protect Your Research: Know Your B6 Mouse
    Protect Your Research: Know Your B6 Mouse
    Many researchers are not aware of the critical importance of genetic background of mice, including the concept of inbred substrains, and how the genetic background of substrains can impact th...
    Speaker: Brian Soper, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    8
     
     
  • FEB 05, 2015 | 6:00 AM
    C.E. CREDITS
    Improving the Post-Operative Recovery of Rodents through Nutrition and Enrichment
    Improving the Post-Operative Recovery of Rodents through Nutrition...
    Laboratory animal surgical models are instrumental in biomedical research; therefore establishing healthy defined animal models is crucial to this research. Surgical procedures produce metab...
    Speaker: Jaime Lecker, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    11
    FEB 04, 2015 | 1:30 PM
    C.E. CREDITS
    The Surgeons Toolbox: outcomes are only as good as the contents of the box
    The Surgeons Toolbox: outcomes are only as good as the contents...
    The field of surgical research has been growing rapidly with the development of new surgical and disease models. An extremely important and often overlooked aspect of creating these models is...
    Speaker: Szczepan Baran, VMD, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    4
    FEB 04, 2015 | 12:00 PM
    C.E. CREDITS
    Standards and regulations for animal use in research: challenges and changes in a chilean university
    Standards and regulations for animal use in research: challenges...
    In Chile, the regulatory context regarding animal use in research is very poor. A legal framework for Animal Care and Use Committees is practically nonexistent. Also, the chilean culture play...
    Speaker: Andrea Leisewitz, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    5
    FEB 04, 2015 | 10:30 AM
    C.E. CREDITS
    Keynote: Practical Tips to Optimize Surgical Results in Rodents
    Keynote: Practical Tips to Optimize Surgical Results in Rodents
    It is the often-ignored simple tips in rodent surgery that make the difference and help minimize postoperative complications and mortality. The presenter will use his years of experience to...
    Speaker: Marcel Perret-Gentil, DVM, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    4
    FEB 04, 2015 | 9:00 AM
    C.E. CREDITS
    Keynote: Applying Principles of Biosafety in Laboratory Animal Facilities
    Keynote: Applying Principles of Biosafety in Laboratory Animal...
    Some commonly accepted principles of biosafety include the strict adherence to standard laboratory practices and techniques, the use of safety equipment such as primary barriers and personal...
    Speaker: James R Swearengen, DVM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    14
     
     
  • FEB 04, 2015 | 7:30 AM
    C.E. CREDITS
    Transportation of Lab Animals - Threats from and Solutions to Animal Extremism interference
    Transportation of Lab Animals - Threats from and Solutions to...
    The transportation of laboratory animals is a critical step in obtaining the proper strain of animal that best fits the researchers needs. Animal Extremist groups have made this transportati...
    Speaker: Ted Wasky
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    4
    FEB 04, 2015 | 7:30 AM
    C.E. CREDITS
    Normal behavior of rodents: understand it, then respect it
    Normal behavior of rodents: understand it, then respect it
    During my presentation, we will discuss:- Normal patterns of behavior (repertoire): social, food intake, territorial, agonistic, anti-predation, sleep and rest, play behavior, grooming, sex...
    Speaker: Marina Snitcofsky, DVM, MSc, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    7
    FEB 04, 2015 | 6:00 AM
    C.E. CREDITS
    Training, Competency Assessment and Best Practice in Aseptic Technique
    Training, Competency Assessment and Best Practice in Aseptic Technique
    Adherence to strict aseptic technique is vital to all types of animal models requiring surgical intervention from both scientific and welfare perspectives. Training of both new and experience...
    Speaker: Angela Kerton, B.VetMed Cert LAS MRCVS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    7
    FEB 04, 2015 | 6:00 AM
    C.E. CREDITS
    PCR testing in rodent health monitoring program: where are we exactly?
    PCR testing in rodent health monitoring program: where are we...
    Soiled-bedding sentinels are not always efficient in detecting pathogens in rodent colonies. In this context, PCR-based testing can be more sensitive and is being advocated as adjunct to trad...
    Speaker: Mathias Leblanc, DVM, PhD, DES, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    33
    JAN 27, 2015 | 2:00 AM
    Catch-and-Release: Extraction and Purification of NGS-Grade DNA and RNA from FFPE Tissue Samples
    Catch-and-Release: Extraction and Purification of NGS-Grade DNA...
    Formalin Fixed, Paraffin Embedded (FFPE) tissues are rapidly being adopted for transcriptome analysis in conjunction with targeted and whole genome sequencing. Harsh formaldehyde fixation an...
    Speaker: Guillaume Durin, PhD
    Sponsored By: Covaris, Inc., Covaris, Inc.
    10
     
     
  • OCT 30, 2014 | 10:30 AM
    Genomics in the Clinic: Promises and Challenges
    Genomics in the Clinic: Promises and Challenges
    Uncovering the genetic lesions underpinning cancer through genomic profiling in a clinical setting could provide insights into possible treatment options for oncologists and their patients. N...
    Speaker: John Carpten, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    12
    OCT 30, 2014 | 10:30 AM
    Development of molecularly targeted imaging agents and identification of novel targets in cancer
    Development of molecularly targeted imaging agents and identification...
    The era of omics has ushered in the hope for personalized medicine. Proteomic and genomic strategies that allow unbiased identification of genes and proteins and their post-transcriptional a...
    Speaker: Kimberly Kelly , PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    16
    OCT 30, 2014 | 9:00 AM
    A head-to-head comparison of whole blood derived samples (cfDNA vs CTC DNA) for cancer research using next-generation sequencing
    A head-to-head comparison of whole blood derived samples (cfDNA...
    Both cell free DNA (cfDNA) and circulating tumor cells (CTC) represent important possible templates for mutation analysis of clinical samples. Each template has different theoretical advantag...
    Speaker: Paul W. Dempsey, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    0
    OCT 30, 2014 | 7:30 AM
    Challenges in biomarker testing in non-small cell lung cancer research
    Challenges in biomarker testing in non-small cell lung cancer...
    Fusion genes play a central role in many cancer types. They have been used to classify malignancy, risk factors, disease prognosis, and companion diagnostic biomarkers for certain approved dr...
    Speaker: Nicola Normanno, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    14
    OCT 30, 2014 | 6:00 AM
    Epigenetic Dysregulation in the Pathogenesis of Myeloproliferative Neoplasms
    Epigenetic Dysregulation in the Pathogenesis of Myeloproliferative...
    When the BCR/ABL1 fusion protein was identified in chronic myelogenous leukemia and the JAK2 V617F mutation was identified in patients with other myeloproliferative neoplasms (MPNs) such as p...
    Speaker: Kristin Landis-Piwowar, PhD, MLS
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    8
     
     
  • OCT 30, 2014 | 6:00 AM
    A platform for combining the results of WES and RNA-seq analysis
    A platform for combining the results of WES and RNA-seq analysis
    Cancer research is being revolutionized by targeted gene panels, whole exome sequencing (WES), whole genome sequencing (WGS), and transcriptome sequencing (RNA-Seq).Many analyses, such as...
    Speaker: Naomi Thomson
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    12
    OCT 29, 2014 | 3:00 PM
    Drug-tailored, efficacy-predictive and prognostic biomarker approaches for proper patient selection
    Drug-tailored, efficacy-predictive and prognostic biomarker approaches...
    Over the last decade we have witnessed tremendous advances in our understanding of the underlying molecular alterations in human cancer. This has stimulated excitement for our ability to deve...
    Speaker: Peter Blume-Jensen, MD, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    0
    OCT 29, 2014 | 3:00 PM
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
    Speaker: Michael J Mann, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    67
    OCT 29, 2014 | 1:30 PM
    PDX Tumor Models for Oncology Research and Preclinical Prediction
    PDX Tumor Models for Oncology Research and Preclinical Prediction
    Patient-derived xenograft (PDX) models can recapitulate patient tumor histopathology, mutational status, gene expression patterns, and drug response with remarkable fidelity. At The Jackson L...
    Speaker: Walter Ausserer, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    50
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