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    Molecular Pathogenesis

    Molecular Pathogenesis: research incorporate the study of host-pathogen interactions at the level of cellular and molecular networks with application to the understanding of virulence factors, host resistance to pathogens, and emerging (and resurgent) infectious disease agents.

    Webinars

    • JUN 03, 2020 | 12:00 PM
      Single cell multiomic analysis of T-cell exhaustion
      Single cell multiomic analysis of T-cell exhaustion
      A key step in the clinical production of CAR T cells is the expansion of engineered T cells. To generate enough cells for viable adoptive cell therapy, cells must be robustly stimulated, whi...
      Speaker: Pratip K. Chattopadhyay
      Presented at: Immuno-Oncology Virtual Event Series 2020
      Sponsored By: BD
      2
      MAY 20, 2020 | 10:00 AM
      How COVID-19 has Changed an Immuno-oncologist's Life: from Optimizing Daily Practice to the Targeted Treatment of Cytokine Storm
      How COVID-19 has Changed an Immuno-oncologist's Life: from Optimizing...
      The spread of severe acute respiratory syndrome coronavirus 2 (SARS CoV2), changed the daily life of medical oncologists. To keep safe both patients and healthy workers is the most important...
      Speaker: PLENARY: Paolo Ascierto, MD
      Presented at: Advancing Science - A Virtual Oncology Conference
      3
      MAY 14, 2020 | 5:40 PM
      First experience with the Ion Torrent Genexus Workflow
      First experience with the Ion Torrent Genexus Workflow
      Operational barriers like complicated workflows and long turnaround times have hindered broad adoption of next-generation sequencing (NGS) in clinical oncology research. The new Ion Torrent...
      Speaker: Dr. Kojo Elenitoba-Johnson
      Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
      6
      MAY 14, 2020 | 5:40 PM
      First experience with the Ion Torrent Genexus Workflow
      First experience with the Ion Torrent Genexus Workflow
      Learning Objectives: 1. Participants will become familiar with basic aspects of the user experience with the Genexus system 2. Participants will learn about preliminary studies using a targe...
      Speaker: Dr. Kojo Elenitoba-Johnson
      Presented at: OncomineWorld Autumn: A virtual NGS education meeting
      1
      MAY 14, 2020 | 3:00 PM
      Analysis of Solid Tumor Genomic Landscape in Liquid Biopsy
      Analysis of Solid Tumor Genomic Landscape in Liquid Biopsy
      Increasing evidence suggests that targeted sequencing of cell free DNA (cfDNA) can provide a comprehensive molecular portrait of solid tumors. However, the concordance between tissue and cfD...
      Speaker: Nicola Normanno, MD
      Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
      8
      MAY 14, 2020 | 3:00 PM
      Analysis of Solid Tumor Genomic Landscape in Liquid Biopsy
      Analysis of Solid Tumor Genomic Landscape in Liquid Biopsy
      Increasing evidence suggests that targeted sequencing of cell free DNA (cfDNA) can provide a comprehensive molecular portrait of solid tumors. However, the concordance between tissue and cfD...
      Speaker: Nicola Normanno, MD
      Presented at: OncomineWorld Autumn: A virtual NGS education meeting
      1
      MAY 13, 2020 | 8:00 AM
      Coronavirus Disease 2019 (COVID-19):  Role of Serologic Testing in Diagnosis and Assessment of Viral Immunity
      Coronavirus Disease 2019 (COVID-19): Role of Serologic Testing...
      Provide education on COVID-19 disease and SARS-CoV-2. Review the types of tests used for the diagnosis of infectious diseases. Discuss approaches to serologic test development. Review the ki...
      Speaker: David M. Engman, MD, PhD
      29 4
      MAR 05, 2020 | 9:00 AM
      An Update on H. pylori testing with a focus on the Houston Consensus recommendations
      An Update on H. pylori testing with a focus on the Houston Consensus...
      Recommendations for key factors in testing and diagnosis of H. pylori infections to include information on appropriate patients for H.pylori testing, current testing options, post treatment...
      Speaker: David Graham, MD
      8
      JAN 14, 2020 | 9:00 AM
      Fecal Elastase-1 - a Biomarker for Pancreatic Exocrine Insufficiency
      Fecal Elastase-1 - a Biomarker for Pancreatic Exocrine Insufficiency
      Fecal elastase-1 – a biomarker for pancreatic exocrine insufficiency(EPI) continues to gain traction as an ideal biomarker for assessing EPI. This presentation will include a review of...
      Speaker: Roy Sherwood, BSc, MSC, DPhil
      Sponsored By: Diasorin S.p.A.
      5
      NOV 15, 2019 | 8:00 AM
      Exosomes and super-resolution microscopy
      Exosomes and super-resolution microscopy
      DATE: November 15, 2019TIME: 8:00am PST, 11:00am EST Exosomes are small vesicles, ranging from 30-120 nanometers in diameter, secreted from cells throughout the human body. The...
      Speaker: Ryan McNamara, PhD
      Sponsored By: ONI
      8
      NOV 06, 2019 | 7:30 AM
      Toward a universal influenza virus vaccine
      Toward a universal influenza virus vaccine
      Since the establishment of reverse genetics techniques to manipulate the influenza virus genome, it has been possible to study viral molecular signatures responsible for virulence, and the ge...
      Speaker: Adolfo Garcia-Sastre, PhD
      Presented at: Influenza Virtual Event Series 2019
      4
      NOV 06, 2019 | 6:00 AM
      Understanding the Pathogenesis of Human Influenza Virus: A Systems Virology Approach
      Understanding the Pathogenesis of Human Influenza Virus: A Systems...
      Multiple factors can affect and impact infection dynamics and virulence produced by influenza virus (IV) infections. Susceptibility factors and host responses can also have major effects in d...
      Speaker: Rafael Medina Silva, PhD
      Presented at: Influenza Virtual Event Series 2019
      1
      SEP 11, 2019 | 1:30 PM
      Development of Machine Learning Algorithms to Data Mine Meta-Omic Characterizations of Complex Microbiota
      Development of Machine Learning Algorithms to Data Mine Meta-Omic...
      Background: The vast majority of all genes are contained within the genomes of the prokaryotes, including the eubacteria and the archaea. These largely single-cellular domains of life thus...
      Speaker: Garth Ehrlich, PhD, FAAAS
      Presented at: Microbiology & Immunology Virtual Event Series 2019
      Sponsored By: PacBio
      4
      SEP 11, 2019 | 12:00 PM
      Understanding Astrovirus Pathogenesis: Who Knew Viruses Had Toxins?
      Understanding Astrovirus Pathogenesis: Who Knew Viruses Had Toxins?
      immunocompromised populations where the virus can cause systemic and even fatal infections. Indeed, we have shown that astrovirus infections are more prevalent than norovirus in our pediatric...
      Speaker: Stacey Schultz-Cherry, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2019
      5
      APR 25, 2019 | 12:00 PM
      Diagnosis and Treatment of Tuberculosis, a Case Study in Challenges and Threats Posed by Infectious Diseases
      Diagnosis and Treatment of Tuberculosis, a Case Study in Challenges...
      Tuberculosis has killed more than one billion people in the last 200 years. It is the oldest and the deadliest human pathogen, recently surpassing HIV. Its adaptation to host and drug pressur...
      Speaker: Faramarz Valafar, PhD
      Presented at: Infectious Disease Virtual Event Series 2019
      2
      APR 25, 2019 | 6:00 AM
      Is Bacterial Vaginosis a Sexually Transmitted Infection?
      Is Bacterial Vaginosis a Sexually Transmitted Infection?
      Despite over 60+ years of research, the etiology of bacterial vaginosis (BV), the most common vaginal infection, remains controversial. Epidemiological data strongly suggest that BV is acquir...
      Speaker: Christina Muzny, MD, MSPH, FACP
      Presented at: Infectious Disease Virtual Event Series 2019
      6
      MAR 26, 2019 | 2:00 PM
      The Role of Endosomes in Prostate Cancer
      The Role of Endosomes in Prostate Cancer
      DATE:  March 26, 2019TIME:  2:00pm PDT, 5:00pm EDT  Prostate cancer is the second most common form of cancer in males, affecting one in eight men by the time t...
      Speaker: Ian Johnson, BSc., Ph.D
      Sponsored By: Thermo Fisher Scientific/Gibco
      7
      NOV 28, 2018 | 7:00 AM
      Discover how single-cell RNA sequencing provides deeper insights into lung cancer biology
      Discover how single-cell RNA sequencing provides deeper insights...
      DATE: November 28, 2018TIME:  7:00AM PSTSingle-cell genomics enables a deep dive into the mechanisms responsible for health and disease, in areas from cancer biology to neurob...
      Speaker: Bernard Thienpont , Annika Branting , Pawel Zajac, Ph.D.
      Sponsored By: Illumina, 10x Genomics
      5
      NOV 21, 2018 | 9:00 AM
      Current Controversies in the Epidemiology, Diagnosis, and Management of Vaginal Infections
      Current Controversies in the Epidemiology, Diagnosis, and Management...
      DATE: November 21,2018TIME:  09:00am PST, 12:00pm EST Vaginal infections are a source of considerable morbidity among women. It is estimated that there are more than 10...
      Speaker: Christina Muzny, MD, MSPH, FACP
      Sponsored By: Roche Molecular Diagnostics
      8
      NOV 15, 2018 | 6:00 AM
      HDV, the most severe form of viral hepatitis.   What you need to know about it
      HDV, the most severe form of viral hepatitis. What you need...
      DATE: November 15,2018TIME:  06:00am PST, 09:00am EST, 3:00pm CET Hepatitis D virus (HDV) is a unique RNA virus that requires the hepatitis B surface antigen (HBsAg) to...
      Speaker: Valentina Svicher, PhD , Ana Avellon, PhD, MD
      Sponsored By: Diasorin
      6
      OCT 30, 2018 | 10:00 AM
      Post-translational Modifications and Data-Independent Acquisitions - Challenges and Opportunities
      Post-translational Modifications and Data-Independent Acquisitions...
      DATE: October 30, 2018TIME: 10:00am PT, 1:00pm ET Identification and quantification of post-translational modifications (PTM) presents a unique challenge to proteomic studies...
      Speaker: Birgit Schilling, PhD , Matthew Stokes, PhD
      Sponsored By: Cell Signaling Technology
      5
      SEP 18, 2018 | 8:00 AM
      High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
      High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
      DATE: September 18,2018TIME: 08:00am PDT, 11:00am EDT CRISPR-Cas9 gene editing strategies have revolutionized our ability to engineer the genomes of diverse cell types and sp...
      Speaker: Judd Hultquist, PhD
      Sponsored By: Horizon Discovery
      7
      SEP 17, 2018 | 8:00 PM
      WEBINAR: High Throughput Production of Autoantigens for Rapid Detection of Multiple Autoimmune Diseases
      WEBINAR: High Throughput Production of Autoantigens for Rapid...
      Current methods for in vitro diagnosis of autoimmune diseases (ADs) are mainly based on the detection of circulating autoantibodies using specific AD autoantigens. A high-quality recombinant...
      Speaker: Aimin Xu, PhD
      Presented at: 3rd Annual 7 Steps of Protein Virtual Event
      1
      JUN 20, 2018 | 9:00 AM
      Identifying Driver Alterations and Therapeutic Options in Cancer
      Identifying Driver Alterations and Therapeutic Options in Cancer
      With prospective clinical sequencing of tumors emerging as a mainstay in cancer care, there is an urgent need for clinical support tools that aid clinicians in their decision making. To this...
      Speaker: Nikolaus Schultz, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      1
    JUN 03, 2020 | 12:00 PM
    Single cell multiomic analysis of T-cell exhaustion
    Single cell multiomic analysis of T-cell exhaustion
    A key step in the clinical production of CAR T cells is the expansion of engineered T cells. To generate enough cells for viable adoptive cell therapy, cells must be robustly stimulated, whi...
    Speaker: Pratip K. Chattopadhyay
    Presented at: Immuno-Oncology Virtual Event Series 2020
    Sponsored By: BD
    2
    MAY 20, 2020 | 10:00 AM
    How COVID-19 has Changed an Immuno-oncologist's Life: from Optimizing Daily Practice to the Targeted Treatment of Cytokine Storm
    How COVID-19 has Changed an Immuno-oncologist's Life: from Optimizing...
    The spread of severe acute respiratory syndrome coronavirus 2 (SARS CoV2), changed the daily life of medical oncologists. To keep safe both patients and healthy workers is the most important...
    Speaker: PLENARY: Paolo Ascierto, MD
    Presented at: Advancing Science - A Virtual Oncology Conference
    3
    MAY 14, 2020 | 5:40 PM
    First experience with the Ion Torrent Genexus Workflow
    First experience with the Ion Torrent Genexus Workflow
    Operational barriers like complicated workflows and long turnaround times have hindered broad adoption of next-generation sequencing (NGS) in clinical oncology research. The new Ion Torrent...
    Speaker: Dr. Kojo Elenitoba-Johnson
    Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
    6
    MAY 14, 2020 | 5:40 PM
    First experience with the Ion Torrent Genexus Workflow
    First experience with the Ion Torrent Genexus Workflow
    Learning Objectives: 1. Participants will become familiar with basic aspects of the user experience with the Genexus system 2. Participants will learn about preliminary studies using a targe...
    Speaker: Dr. Kojo Elenitoba-Johnson
    Presented at: OncomineWorld Autumn: A virtual NGS education meeting
    1
    MAY 14, 2020 | 3:00 PM
    Analysis of Solid Tumor Genomic Landscape in Liquid Biopsy
    Analysis of Solid Tumor Genomic Landscape in Liquid Biopsy
    Increasing evidence suggests that targeted sequencing of cell free DNA (cfDNA) can provide a comprehensive molecular portrait of solid tumors. However, the concordance between tissue and cfD...
    Speaker: Nicola Normanno, MD
    Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
    8
     
     
  • MAY 14, 2020 | 3:00 PM
    Analysis of Solid Tumor Genomic Landscape in Liquid Biopsy
    Analysis of Solid Tumor Genomic Landscape in Liquid Biopsy
    Increasing evidence suggests that targeted sequencing of cell free DNA (cfDNA) can provide a comprehensive molecular portrait of solid tumors. However, the concordance between tissue and cfD...
    Speaker: Nicola Normanno, MD
    Presented at: OncomineWorld Autumn: A virtual NGS education meeting
    1
    MAY 13, 2020 | 8:00 AM
    Coronavirus Disease 2019 (COVID-19):  Role of Serologic Testing in Diagnosis and Assessment of Viral Immunity
    Coronavirus Disease 2019 (COVID-19): Role of Serologic Testing...
    Provide education on COVID-19 disease and SARS-CoV-2. Review the types of tests used for the diagnosis of infectious diseases. Discuss approaches to serologic test development. Review the ki...
    Speaker: David M. Engman, MD, PhD
    29 4
    MAR 05, 2020 | 9:00 AM
    An Update on H. pylori testing with a focus on the Houston Consensus recommendations
    An Update on H. pylori testing with a focus on the Houston Consensus...
    Recommendations for key factors in testing and diagnosis of H. pylori infections to include information on appropriate patients for H.pylori testing, current testing options, post treatment...
    Speaker: David Graham, MD
    8
    JAN 14, 2020 | 9:00 AM
    Fecal Elastase-1 - a Biomarker for Pancreatic Exocrine Insufficiency
    Fecal Elastase-1 - a Biomarker for Pancreatic Exocrine Insufficiency
    Fecal elastase-1 – a biomarker for pancreatic exocrine insufficiency(EPI) continues to gain traction as an ideal biomarker for assessing EPI. This presentation will include a review of...
    Speaker: Roy Sherwood, BSc, MSC, DPhil
    Sponsored By: Diasorin S.p.A.
    5
    NOV 15, 2019 | 8:00 AM
    Exosomes and super-resolution microscopy
    Exosomes and super-resolution microscopy
    DATE: November 15, 2019TIME: 8:00am PST, 11:00am EST Exosomes are small vesicles, ranging from 30-120 nanometers in diameter, secreted from cells throughout the human body. The...
    Speaker: Ryan McNamara, PhD
    Sponsored By: ONI
    8
     
     
  • NOV 06, 2019 | 7:30 AM
    Toward a universal influenza virus vaccine
    Toward a universal influenza virus vaccine
    Since the establishment of reverse genetics techniques to manipulate the influenza virus genome, it has been possible to study viral molecular signatures responsible for virulence, and the ge...
    Speaker: Adolfo Garcia-Sastre, PhD
    Presented at: Influenza Virtual Event Series 2019
    4
    NOV 06, 2019 | 6:00 AM
    Understanding the Pathogenesis of Human Influenza Virus: A Systems Virology Approach
    Understanding the Pathogenesis of Human Influenza Virus: A Systems...
    Multiple factors can affect and impact infection dynamics and virulence produced by influenza virus (IV) infections. Susceptibility factors and host responses can also have major effects in d...
    Speaker: Rafael Medina Silva, PhD
    Presented at: Influenza Virtual Event Series 2019
    1
    SEP 11, 2019 | 1:30 PM
    Development of Machine Learning Algorithms to Data Mine Meta-Omic Characterizations of Complex Microbiota
    Development of Machine Learning Algorithms to Data Mine Meta-Omic...
    Background: The vast majority of all genes are contained within the genomes of the prokaryotes, including the eubacteria and the archaea. These largely single-cellular domains of life thus...
    Speaker: Garth Ehrlich, PhD, FAAAS
    Presented at: Microbiology & Immunology Virtual Event Series 2019
    Sponsored By: PacBio
    4
    SEP 11, 2019 | 12:00 PM
    Understanding Astrovirus Pathogenesis: Who Knew Viruses Had Toxins?
    Understanding Astrovirus Pathogenesis: Who Knew Viruses Had Toxins?
    immunocompromised populations where the virus can cause systemic and even fatal infections. Indeed, we have shown that astrovirus infections are more prevalent than norovirus in our pediatric...
    Speaker: Stacey Schultz-Cherry, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2019
    5
    APR 25, 2019 | 12:00 PM
    Diagnosis and Treatment of Tuberculosis, a Case Study in Challenges and Threats Posed by Infectious Diseases
    Diagnosis and Treatment of Tuberculosis, a Case Study in Challenges...
    Tuberculosis has killed more than one billion people in the last 200 years. It is the oldest and the deadliest human pathogen, recently surpassing HIV. Its adaptation to host and drug pressur...
    Speaker: Faramarz Valafar, PhD
    Presented at: Infectious Disease Virtual Event Series 2019
    2
     
     
  • APR 25, 2019 | 6:00 AM
    Is Bacterial Vaginosis a Sexually Transmitted Infection?
    Is Bacterial Vaginosis a Sexually Transmitted Infection?
    Despite over 60+ years of research, the etiology of bacterial vaginosis (BV), the most common vaginal infection, remains controversial. Epidemiological data strongly suggest that BV is acquir...
    Speaker: Christina Muzny, MD, MSPH, FACP
    Presented at: Infectious Disease Virtual Event Series 2019
    6
    MAR 26, 2019 | 2:00 PM
    The Role of Endosomes in Prostate Cancer
    The Role of Endosomes in Prostate Cancer
    DATE:  March 26, 2019TIME:  2:00pm PDT, 5:00pm EDT  Prostate cancer is the second most common form of cancer in males, affecting one in eight men by the time t...
    Speaker: Ian Johnson, BSc., Ph.D
    Sponsored By: Thermo Fisher Scientific/Gibco
    7
    NOV 28, 2018 | 7:00 AM
    Discover how single-cell RNA sequencing provides deeper insights into lung cancer biology
    Discover how single-cell RNA sequencing provides deeper insights...
    DATE: November 28, 2018TIME:  7:00AM PSTSingle-cell genomics enables a deep dive into the mechanisms responsible for health and disease, in areas from cancer biology to neurob...
    Speaker: Bernard Thienpont , Annika Branting , Pawel Zajac, Ph.D.
    Sponsored By: Illumina, 10x Genomics
    5
    NOV 21, 2018 | 9:00 AM
    Current Controversies in the Epidemiology, Diagnosis, and Management of Vaginal Infections
    Current Controversies in the Epidemiology, Diagnosis, and Management...
    DATE: November 21,2018TIME:  09:00am PST, 12:00pm EST Vaginal infections are a source of considerable morbidity among women. It is estimated that there are more than 10...
    Speaker: Christina Muzny, MD, MSPH, FACP
    Sponsored By: Roche Molecular Diagnostics
    8
    NOV 15, 2018 | 6:00 AM
    HDV, the most severe form of viral hepatitis.   What you need to know about it
    HDV, the most severe form of viral hepatitis. What you need...
    DATE: November 15,2018TIME:  06:00am PST, 09:00am EST, 3:00pm CET Hepatitis D virus (HDV) is a unique RNA virus that requires the hepatitis B surface antigen (HBsAg) to...
    Speaker: Valentina Svicher, PhD , Ana Avellon, PhD, MD
    Sponsored By: Diasorin
    6
     
     
  • OCT 30, 2018 | 10:00 AM
    Post-translational Modifications and Data-Independent Acquisitions - Challenges and Opportunities
    Post-translational Modifications and Data-Independent Acquisitions...
    DATE: October 30, 2018TIME: 10:00am PT, 1:00pm ET Identification and quantification of post-translational modifications (PTM) presents a unique challenge to proteomic studies...
    Speaker: Birgit Schilling, PhD , Matthew Stokes, PhD
    Sponsored By: Cell Signaling Technology
    5
    SEP 18, 2018 | 8:00 AM
    High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
    High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
    DATE: September 18,2018TIME: 08:00am PDT, 11:00am EDT CRISPR-Cas9 gene editing strategies have revolutionized our ability to engineer the genomes of diverse cell types and sp...
    Speaker: Judd Hultquist, PhD
    Sponsored By: Horizon Discovery
    7
    SEP 17, 2018 | 8:00 PM
    WEBINAR: High Throughput Production of Autoantigens for Rapid Detection of Multiple Autoimmune Diseases
    WEBINAR: High Throughput Production of Autoantigens for Rapid...
    Current methods for in vitro diagnosis of autoimmune diseases (ADs) are mainly based on the detection of circulating autoantibodies using specific AD autoantigens. A high-quality recombinant...
    Speaker: Aimin Xu, PhD
    Presented at: 3rd Annual 7 Steps of Protein Virtual Event
    1
    JUN 20, 2018 | 9:00 AM
    Identifying Driver Alterations and Therapeutic Options in Cancer
    Identifying Driver Alterations and Therapeutic Options in Cancer
    With prospective clinical sequencing of tumors emerging as a mainstay in cancer care, there is an urgent need for clinical support tools that aid clinicians in their decision making. To this...
    Speaker: Nikolaus Schultz, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
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