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    Safety Assessment

    Safety Assessment: like risk assessment, is the process of characterizing the nature and likelihood of a harmful effect to individuals or populations from certain human activities.

    Webinars

    • JAN 01, 2020 | 6:00 AM
      3D-Micro Tissues in Translational Toxicology and Disease Modelling
      3D-Micro Tissues in Translational Toxicology and Disease Modelling
      The aim of the lecture is to give an insight into the use of 3D liver micro tissues (3D liMTs) in drug discovery and translational safety. In translational toxicology, 3D LiMTs have a high i...
      Speaker: Armin Wolf, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      JAN 01, 2020 | 6:00 AM
      Human Tissue models for better therapies
      Human Tissue models for better therapies
      The OrganoPlate is a microtiterplate based Organ-on-a-Chip platform for high throughput drug safety and efficacy screening. It contains up to 96 cell culture chambers that allow co-culture o...
      Speaker: Sebastiaan Trietsch, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      NOV 14, 2019 | 10:30 AM
      Interferences with thyroid function tests and patient safety
      Interferences with thyroid function tests and patient safety
      Thyroid function tests play a central role to assess thyroid function and are valuable companions for clinicians. The evolution of the tests is permanent and clinical laboratories are key pla...
      Speaker: Damien Gruson, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
      2
      NOV 14, 2019 | 9:00 AM
      Drug testing in Regulatory Monitoring
      Drug testing in Regulatory Monitoring
      Random drug testing is used as a preventive and detection tool for drug or alcohol use, and medication compliance in the monitoring of regulatory and treatment compliance monitoring. Urine sc...
      Speaker: John Furman, PhD, MSN, COHN-S
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
      5 1
      NOV 14, 2019 | 9:00 AM
      The Role of Proficiency Testing in Achieving Global Outcomes for Hemoglobin A1c
      The Role of Proficiency Testing in Achieving Global Outcomes for...
      Central to the diagnosis and management of patients with diabetes mellitus is the measurement of hemoglobin A1c (HbA1c). Major studies have defined the therapeutic targets of HbA1c in order...
      Speaker: Paul Yip, PhD, FCACB, DABCC
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
      2
      SEP 26, 2019 | 6:00 AM
      Profiling Focal Areas of FFPE Tissue: Spatial Transcriptomics and the Challenge of Low Input Samples
      Profiling Focal Areas of FFPE Tissue: Spatial Transcriptomics...
      Spatial transcriptomics methods permit gene expression from focal areas within a tissue to be profiled while maintaining the morphologic context of the tissue microenvironment. This presentat...
      Speaker: Bruce Seligmann, PhD
      Presented at: Cell Biology Virtual Event Series 2019
      1
      MAR 28, 2019 | 10:30 AM
      Medical Cannabis Pharmacogenomics and Drug Interactions
      Medical Cannabis Pharmacogenomics and Drug Interactions
      The therapeutic applications of medical cannabis and cannabinoid drugs is controversial, however the number of medical conditions in which cannabinoids and cannabis have shown promise as ther...
      Speaker: Jahan Marcu, PhD
      Presented at: Cannabis Sciences Virtual Event Series 2019
      3
      MAR 28, 2019 | 9:00 AM
      Analysis of Cannabis for Pesticides and Mycotoxins Using UPLC-MS/MS and GC-MS/MS
      Analysis of Cannabis for Pesticides and Mycotoxins Using UPLC-MS/MS...
      Quantitative methods for residual pesticides and mycotoxins analysis in cannabis should provide reliable coverage and robust methodology for the entire list of analytes to fulfill the state m...
      Speaker: Marian Twohig, PhD
      Presented at: Cannabis Sciences Virtual Event Series 2019
      4
      FEB 14, 2019 | 12:00 PM
      Application of Micro-Physiological Systems for Respiratory Drug Discovery: Opportunities and Challenges
      Application of Micro-Physiological Systems for Respiratory Drug...
      The lung is a highly complex organ, comprised of more than 40 cell types that are responsible for various important functions, the lung’s complexity contributes to the subsequent challe...
      Speaker: David Rowlands, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      1
      FEB 14, 2019 | 10:30 AM
      Integrating In Vitro Microtissues and In Vivo endpoints in Drug Discovery & Development
      Integrating In Vitro Microtissues and In Vivo endpoints in Drug...
      This presentation will discuss and review the promise and potential of 3D Microtissues, and the challenges of using these Microtissues as Hazard ID tools. Lastly, we will discuss the potentia...
      Speaker: Matthew Wagoner, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      2
      FEB 13, 2019 | 10:30 AM
      Qualitative, Biased, Personal and Speculative Remarks on Digitization, Digitalization & Digital Transformation
      Qualitative, Biased, Personal and Speculative Remarks on Digitization,...
      A collection of opinions, questions and other assorted thoughts about the intersection of these developing technologies and preclinical studies primarily focused on the early discovery (as op...
      Speaker: Sean Maguire, VMD, MS, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      4
      FEB 13, 2019 | 10:30 AM
      Accurate Clinical Concentration-Response Predictions for Cardiac Arrhythmias Using a Population-Based in Vitro/In Silico Model
      Accurate Clinical Concentration-Response Predictions for Cardiac...
      Xenobiotic-induced cardiotoxicity is a major concern for both pharmaceuticals and chemicals in the marketplace. For drugs, "Thorough QT/corrected QT (QTc)" (TQT) studies are corners...
      Speaker: Weihsueh Chiu, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      5 1
      NOV 27, 2018 | 8:00 AM
      Understand the rationale behind the Q-TOF LC/MS that stably sustains sub-ppm mass accuracy
      Understand the rationale behind the Q-TOF LC/MS that stably sustains...
      DATE: November 27, 2018TIME: 8:00am PTHigh-resolution, accurate-mass (HRAM) mass spectrometers (MS) are a class of MS instrumentation with capability to resolve complex sample matr...
      Speaker: Atsuhiko (Ash) Toyama, PhD
      Sponsored By: Shimadzu
      3
      NOV 27, 2018 | 1:00 AM
      Understand the rationale behind the Q-TOF LC/MS that stably sustains sub-ppm mass accuracy.
      Understand the rationale behind the Q-TOF LC/MS that stably sustains...
      DATE: November 27, 2018TIME: 1:00am PTHigh-resolution, accurate-mass (HRAM) mass spectrometers (MS) are a class of MS instrumentation with capability to resolve complex sample matr...
      Speaker: Atsuhiko (Ash) Toyama, PhD
      Sponsored By: Shimadzu
      2
      OCT 23, 2018 | 7:00 AM
      FLIPR 1536-well application in high throughput screening
      FLIPR 1536-well application in high throughput screening
      DATE: October 23, 2018TIME: 7:00AM PDTHigh Throughput Screening for the European Lead Factory (ELF) has been performed at Pivot Park Screening Centre (PPSC). 72 HTS campaigns have...
      Speaker: Helma Van Den Hurk, PhD , Tsang Wai Lam, BSc
      Sponsored By: Molecular Devices
      4
      SEP 12, 2018 | 9:00 AM
      Antimicrobial Stewardship - Its Role in Managing Antibiotic Resistance
      Antimicrobial Stewardship - Its Role in Managing Antibiotic Resistance
      Antibiotic resistance is a national and global public health crisis.  Each year in the United States (US), at least 2 million people become infected with antibiotic-resistant bacteria an...
      Speaker: Haley Appaneal, Pharm D.
      Presented at: Microbiology & Immunology Virtual Event Series 2018
      3
      SEP 11, 2018 | 7:00 AM
      Answering the Challenges of Cell Viability and Reporter Gene Assays Screening Cost and Quality
      Answering the Challenges of Cell Viability and Reporter Gene Assays...
      DATE: September 11, 2018TIME: 07:00AM PDTWith increasing safety requirements, and time and financial pressure, the development of new drugs, and the execution of basic research p...
      Speaker: Vincent Dupriez, PhD , Jeanine Hinterneder, PhD , Maria Kuzikov, MSc
      Sponsored By: Revvity
      5
      JUN 20, 2018 | 10:30 AM
      A Pharmacogenomic Approach to Medical Cannabis
      A Pharmacogenomic Approach to Medical Cannabis
      The therapeutic applications of medical cannabis and cannabinoid drugs is controversial, however the number of medical conditions in which cannabinoids and cannabis have shown promise as ther...
      Speaker: Jahan Marcu, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      1
      MAY 30, 2018 | 6:00 AM
      Phenotypic Profiling for Improving Drug Discovery Productivity
      Phenotypic Profiling for Improving Drug Discovery Productivity
      The pharmaceutical industry’s productivity crisis is well known with >90% of drug candidates failing in clinical testing, primarily due to unexpected toxicity or lack of efficacy. &n...
      Speaker: Ellen Berg, PhD
      Presented at: Lab Automation Virtual Event Series 2018
      2 1
      MAR 28, 2018 | 6:00 AM
      Extraction and the Labeling of Cannabis Products
      Extraction and the Labeling of Cannabis Products
      There is growing consumer and patient demand for products containing cannabidiol (CBD) and other constituents of the cannabis plant, due to their purported medicinal benefits for a myriad of...
      Speaker: Jahan Marcu, PhD
      Presented at: Cannabis Sciences Virtual Event Series 2018
      6
      NOV 16, 2017 | 10:00 AM
      WEBINAR: Tracking neural network activity in the B-27â„¢ Plus Neuronal Culture System with a Maestro Pro MEA platform
      WEBINAR: Tracking neural network activity in the B-27â„¢ Plus Neuronal...
      DATE: November 16, 2017TIME: 10:00am PST, 1:00pm EST, Neuronal networks play a fundamental role in the brain, with many diseases linked to disruptions in network activity.  Cell-ba...
      Speaker: Daniel Millard, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      NOV 09, 2017 | 6:00 AM
      Biosafety Risk Assessment Fundamentals for Clinical Laboratories
      Biosafety Risk Assessment Fundamentals for Clinical Laboratories
      This session will review and describe the basic steps of a biosafety risk assessment for clinical laboratories.  The risk of exposure to infectious agents exists in every clinical labora...
      Speaker: Michael Pentella, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
      9
      MAY 09, 2017 | 7:00 AM
      WEBINAR: Advanced assays for high-throughput assessment of ion channel inhibition and cardiac toxicity
      WEBINAR: Advanced assays for high-throughput assessment of ion...
      DATE: May 9th, 2017TIME: 7:00AM PDT, 10:00AM ET, 2:00PM GMT Early detection and elimination of new chemical entities with cardiac or hERG liability could substantially improve...
      Speaker: Beiyan Zou, PhD , Oksana Sirenko, PhD
      Sponsored By: Molecular Devices
      6
      FEB 22, 2017 | 6:00 AM
      GenomeFIRST â„¢ A new paradigm for the return of genomic results
      GenomeFIRST â„¢ A new paradigm for the return of genomic results
      The starting point for an interaction between a patient and a clinician is almost always a set of clinical facts (aka a phenotype). Phenotype-first medicine is the standard way in which the p...
      Speaker: Marc Williams, MD
      Presented at: Precision Medicine Virtual Event Series 2017
      4
    JAN 01, 2020 | 6:00 AM
    3D-Micro Tissues in Translational Toxicology and Disease Modelling
    3D-Micro Tissues in Translational Toxicology and Disease Modelling
    The aim of the lecture is to give an insight into the use of 3D liver micro tissues (3D liMTs) in drug discovery and translational safety. In translational toxicology, 3D LiMTs have a high i...
    Speaker: Armin Wolf, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    JAN 01, 2020 | 6:00 AM
    Human Tissue models for better therapies
    Human Tissue models for better therapies
    The OrganoPlate is a microtiterplate based Organ-on-a-Chip platform for high throughput drug safety and efficacy screening. It contains up to 96 cell culture chambers that allow co-culture o...
    Speaker: Sebastiaan Trietsch, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    NOV 14, 2019 | 10:30 AM
    Interferences with thyroid function tests and patient safety
    Interferences with thyroid function tests and patient safety
    Thyroid function tests play a central role to assess thyroid function and are valuable companions for clinicians. The evolution of the tests is permanent and clinical laboratories are key pla...
    Speaker: Damien Gruson, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
    2
    NOV 14, 2019 | 9:00 AM
    Drug testing in Regulatory Monitoring
    Drug testing in Regulatory Monitoring
    Random drug testing is used as a preventive and detection tool for drug or alcohol use, and medication compliance in the monitoring of regulatory and treatment compliance monitoring. Urine sc...
    Speaker: John Furman, PhD, MSN, COHN-S
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
    5 1
    NOV 14, 2019 | 9:00 AM
    The Role of Proficiency Testing in Achieving Global Outcomes for Hemoglobin A1c
    The Role of Proficiency Testing in Achieving Global Outcomes for...
    Central to the diagnosis and management of patients with diabetes mellitus is the measurement of hemoglobin A1c (HbA1c). Major studies have defined the therapeutic targets of HbA1c in order...
    Speaker: Paul Yip, PhD, FCACB, DABCC
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
    2
     
     
  • SEP 26, 2019 | 6:00 AM
    Profiling Focal Areas of FFPE Tissue: Spatial Transcriptomics and the Challenge of Low Input Samples
    Profiling Focal Areas of FFPE Tissue: Spatial Transcriptomics...
    Spatial transcriptomics methods permit gene expression from focal areas within a tissue to be profiled while maintaining the morphologic context of the tissue microenvironment. This presentat...
    Speaker: Bruce Seligmann, PhD
    Presented at: Cell Biology Virtual Event Series 2019
    1
    MAR 28, 2019 | 10:30 AM
    Medical Cannabis Pharmacogenomics and Drug Interactions
    Medical Cannabis Pharmacogenomics and Drug Interactions
    The therapeutic applications of medical cannabis and cannabinoid drugs is controversial, however the number of medical conditions in which cannabinoids and cannabis have shown promise as ther...
    Speaker: Jahan Marcu, PhD
    Presented at: Cannabis Sciences Virtual Event Series 2019
    3
    MAR 28, 2019 | 9:00 AM
    Analysis of Cannabis for Pesticides and Mycotoxins Using UPLC-MS/MS and GC-MS/MS
    Analysis of Cannabis for Pesticides and Mycotoxins Using UPLC-MS/MS...
    Quantitative methods for residual pesticides and mycotoxins analysis in cannabis should provide reliable coverage and robust methodology for the entire list of analytes to fulfill the state m...
    Speaker: Marian Twohig, PhD
    Presented at: Cannabis Sciences Virtual Event Series 2019
    4
    FEB 14, 2019 | 12:00 PM
    Application of Micro-Physiological Systems for Respiratory Drug Discovery: Opportunities and Challenges
    Application of Micro-Physiological Systems for Respiratory Drug...
    The lung is a highly complex organ, comprised of more than 40 cell types that are responsible for various important functions, the lung’s complexity contributes to the subsequent challe...
    Speaker: David Rowlands, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    1
    FEB 14, 2019 | 10:30 AM
    Integrating In Vitro Microtissues and In Vivo endpoints in Drug Discovery & Development
    Integrating In Vitro Microtissues and In Vivo endpoints in Drug...
    This presentation will discuss and review the promise and potential of 3D Microtissues, and the challenges of using these Microtissues as Hazard ID tools. Lastly, we will discuss the potentia...
    Speaker: Matthew Wagoner, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    2
     
     
  • FEB 13, 2019 | 10:30 AM
    Qualitative, Biased, Personal and Speculative Remarks on Digitization, Digitalization & Digital Transformation
    Qualitative, Biased, Personal and Speculative Remarks on Digitization,...
    A collection of opinions, questions and other assorted thoughts about the intersection of these developing technologies and preclinical studies primarily focused on the early discovery (as op...
    Speaker: Sean Maguire, VMD, MS, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    4
    FEB 13, 2019 | 10:30 AM
    Accurate Clinical Concentration-Response Predictions for Cardiac Arrhythmias Using a Population-Based in Vitro/In Silico Model
    Accurate Clinical Concentration-Response Predictions for Cardiac...
    Xenobiotic-induced cardiotoxicity is a major concern for both pharmaceuticals and chemicals in the marketplace. For drugs, "Thorough QT/corrected QT (QTc)" (TQT) studies are corners...
    Speaker: Weihsueh Chiu, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    5 1
    NOV 27, 2018 | 8:00 AM
    Understand the rationale behind the Q-TOF LC/MS that stably sustains sub-ppm mass accuracy
    Understand the rationale behind the Q-TOF LC/MS that stably sustains...
    DATE: November 27, 2018TIME: 8:00am PTHigh-resolution, accurate-mass (HRAM) mass spectrometers (MS) are a class of MS instrumentation with capability to resolve complex sample matr...
    Speaker: Atsuhiko (Ash) Toyama, PhD
    Sponsored By: Shimadzu
    3
    NOV 27, 2018 | 1:00 AM
    Understand the rationale behind the Q-TOF LC/MS that stably sustains sub-ppm mass accuracy.
    Understand the rationale behind the Q-TOF LC/MS that stably sustains...
    DATE: November 27, 2018TIME: 1:00am PTHigh-resolution, accurate-mass (HRAM) mass spectrometers (MS) are a class of MS instrumentation with capability to resolve complex sample matr...
    Speaker: Atsuhiko (Ash) Toyama, PhD
    Sponsored By: Shimadzu
    2
    OCT 23, 2018 | 7:00 AM
    FLIPR 1536-well application in high throughput screening
    FLIPR 1536-well application in high throughput screening
    DATE: October 23, 2018TIME: 7:00AM PDTHigh Throughput Screening for the European Lead Factory (ELF) has been performed at Pivot Park Screening Centre (PPSC). 72 HTS campaigns have...
    Speaker: Helma Van Den Hurk, PhD , Tsang Wai Lam, BSc
    Sponsored By: Molecular Devices
    4
     
     
  • SEP 12, 2018 | 9:00 AM
    Antimicrobial Stewardship - Its Role in Managing Antibiotic Resistance
    Antimicrobial Stewardship - Its Role in Managing Antibiotic Resistance
    Antibiotic resistance is a national and global public health crisis.  Each year in the United States (US), at least 2 million people become infected with antibiotic-resistant bacteria an...
    Speaker: Haley Appaneal, Pharm D.
    Presented at: Microbiology & Immunology Virtual Event Series 2018
    3
    SEP 11, 2018 | 7:00 AM
    Answering the Challenges of Cell Viability and Reporter Gene Assays Screening Cost and Quality
    Answering the Challenges of Cell Viability and Reporter Gene Assays...
    DATE: September 11, 2018TIME: 07:00AM PDTWith increasing safety requirements, and time and financial pressure, the development of new drugs, and the execution of basic research p...
    Speaker: Vincent Dupriez, PhD , Jeanine Hinterneder, PhD , Maria Kuzikov, MSc
    Sponsored By: Revvity
    5
    JUN 20, 2018 | 10:30 AM
    A Pharmacogenomic Approach to Medical Cannabis
    A Pharmacogenomic Approach to Medical Cannabis
    The therapeutic applications of medical cannabis and cannabinoid drugs is controversial, however the number of medical conditions in which cannabinoids and cannabis have shown promise as ther...
    Speaker: Jahan Marcu, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    1
    MAY 30, 2018 | 6:00 AM
    Phenotypic Profiling for Improving Drug Discovery Productivity
    Phenotypic Profiling for Improving Drug Discovery Productivity
    The pharmaceutical industry’s productivity crisis is well known with >90% of drug candidates failing in clinical testing, primarily due to unexpected toxicity or lack of efficacy. &n...
    Speaker: Ellen Berg, PhD
    Presented at: Lab Automation Virtual Event Series 2018
    2 1
    MAR 28, 2018 | 6:00 AM
    Extraction and the Labeling of Cannabis Products
    Extraction and the Labeling of Cannabis Products
    There is growing consumer and patient demand for products containing cannabidiol (CBD) and other constituents of the cannabis plant, due to their purported medicinal benefits for a myriad of...
    Speaker: Jahan Marcu, PhD
    Presented at: Cannabis Sciences Virtual Event Series 2018
    6
     
     
  • NOV 16, 2017 | 10:00 AM
    WEBINAR: Tracking neural network activity in the B-27â„¢ Plus Neuronal Culture System with a Maestro Pro MEA platform
    WEBINAR: Tracking neural network activity in the B-27â„¢ Plus Neuronal...
    DATE: November 16, 2017TIME: 10:00am PST, 1:00pm EST, Neuronal networks play a fundamental role in the brain, with many diseases linked to disruptions in network activity.  Cell-ba...
    Speaker: Daniel Millard, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
    NOV 09, 2017 | 6:00 AM
    Biosafety Risk Assessment Fundamentals for Clinical Laboratories
    Biosafety Risk Assessment Fundamentals for Clinical Laboratories
    This session will review and describe the basic steps of a biosafety risk assessment for clinical laboratories.  The risk of exposure to infectious agents exists in every clinical labora...
    Speaker: Michael Pentella, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
    9
    MAY 09, 2017 | 7:00 AM
    WEBINAR: Advanced assays for high-throughput assessment of ion channel inhibition and cardiac toxicity
    WEBINAR: Advanced assays for high-throughput assessment of ion...
    DATE: May 9th, 2017TIME: 7:00AM PDT, 10:00AM ET, 2:00PM GMT Early detection and elimination of new chemical entities with cardiac or hERG liability could substantially improve...
    Speaker: Beiyan Zou, PhD , Oksana Sirenko, PhD
    Sponsored By: Molecular Devices
    6
    FEB 22, 2017 | 6:00 AM
    GenomeFIRST â„¢ A new paradigm for the return of genomic results
    GenomeFIRST â„¢ A new paradigm for the return of genomic results
    The starting point for an interaction between a patient and a clinician is almost always a set of clinical facts (aka a phenotype). Phenotype-first medicine is the standard way in which the p...
    Speaker: Marc Williams, MD
    Presented at: Precision Medicine Virtual Event Series 2017
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