Since its initial description more than 70 years ago, autism spectrum disorder (ASD) has been diagnosed more frequently in boys. However, we remain unsure of why males are affected in greater...
Biomedical research depends on the use of model systems to explore basic biology, probe disease mechanisms, and conduct drug discovery and development. However, results from such systems are...
Complex animal behavior is produced by dynamic interactions between discrete regions of the brain. As such, defining functional connections between brain regions is critical in gaining a full...
G-protein coupled receptors (GPCRs) represent the single largest class of druggable targets in the human genome. Of the 390 or so druggable and non-olfactory human GPCRs there exist many whic...
Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the Methyl CpG Binding Protein 2 (MECP2) gene. In mouse models of RTT, deficits in long-term potentiation (LTP) at...
Preclinical translational imaging, and specifically molecular imaging methods such as positron emission tomography (PET) or single photon emission computed tomography (SPECT) as well as magne...
Compassion fatigue, or the state of chronic stress for those caring for people or animals in distress, can affect anyone working in the lab animal sciences. This can even affect employe...
The translation gap in biomedical research can be attributed in part to differences in how outcomes are assessed in preclinical research and in the clinic. Reasons for these mismatches includ...
Analgesics are commonly employed drugs for perioperative procedures and are required for painful procedures. They include not only non-steroidal anti-inflammatory drugs (NSAIDs) but also opio...
Assessment of how changes in husbandry affect an animal can be challenging as most common methods of assessment, such as corticosterone levels, are more reliable for assessment of acute stres...
Digital technology is improving the speed and accuracy of all the world’s work processes and activities, the including the research vivarium. This presentation will address some...
There is a growing debate about the usefulness of animal studies in biomedical research and drug development. Some of the challenges in translation from animals to human patients may be from...
Nonterminal blood collection from mice is frequently performed in biomedical research. Multiple phlebotomy sites and restraint techniques are available to investigators. Methods that minimize...
The aerodigestive tract is a combination of the respiratory tract and the upper portion of the digestive tract. As these two organ systems share many of the necessary structures used for swal...
Introduction:The cannulation of the cisterna magna in the rat is a valuable model for in-vivo sampling of cerebrospinal fluid for studying delivery of new drugs into the central nervous sys...
Compassion Fatigue can affect all those that care for and work with laboratory animals, including husbandry staff, veterinary staff, researchers, and other support staff. It is known as the &...
The ability to rapidly and accurately identify pain in mice is critical for providing them optimal care and welfare. To meet this need, we developed and validated the Grooming Transfer Test (...
This session will explore the interpretation of multi-species scattergrams in normal and pathologic conditions. Numerous case studies will be reviewed....
Tuberculosis (TB) is the No.1 cause of death due to a single infectious agent in the world today. According to the global report from World Health Organization, one third of world population...
Conspecific aggression is a common problem amongst laboratory housed male mice. While C57BL/6 are not the most aggressive strain we house, they are exceedingly common, and dealing with...
Welfare First, a programme developed to recognise the importance of welfare within the life sciences sector and to meet the aims of its position statement. Animal welfare is a priority,...
There is a considerable interest and need for evidence-based recommendations regarding the social housing of laboratory rabbits. This presentation will review the principles surrounding the s...
DATE: January 25, 2018TIME: 8:00AM PST, 10:00AM CSTProstate cancer (PCa) is the most common noncutaneous malignancy in men in the US. A significant fraction of advanced PCa treate...
DATE: November 15, 2017TIME: 09:00am PST, 12:00pm ESTMicroRNAs (miRNA) are a class of small non-coding RNAs (approximately 21 nt long) that bind complementary sequences in target mRNAs...
Since its initial description more than 70 years ago, autism spectrum disorder (ASD) has been diagnosed more frequently in boys. However, we remain unsure of why males are affected in greater...
Biomedical research depends on the use of model systems to explore basic biology, probe disease mechanisms, and conduct drug discovery and development. However, results from such systems are...
Complex animal behavior is produced by dynamic interactions between discrete regions of the brain. As such, defining functional connections between brain regions is critical in gaining a full...
G-protein coupled receptors (GPCRs) represent the single largest class of druggable targets in the human genome. Of the 390 or so druggable and non-olfactory human GPCRs there exist many whic...
Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the Methyl CpG Binding Protein 2 (MECP2) gene. In mouse models of RTT, deficits in long-term potentiation (LTP) at...
Preclinical translational imaging, and specifically molecular imaging methods such as positron emission tomography (PET) or single photon emission computed tomography (SPECT) as well as magne...
Compassion fatigue, or the state of chronic stress for those caring for people or animals in distress, can affect anyone working in the lab animal sciences. This can even affect employe...
The translation gap in biomedical research can be attributed in part to differences in how outcomes are assessed in preclinical research and in the clinic. Reasons for these mismatches includ...
Analgesics are commonly employed drugs for perioperative procedures and are required for painful procedures. They include not only non-steroidal anti-inflammatory drugs (NSAIDs) but also opio...
Assessment of how changes in husbandry affect an animal can be challenging as most common methods of assessment, such as corticosterone levels, are more reliable for assessment of acute stres...
Digital technology is improving the speed and accuracy of all the world’s work processes and activities, the including the research vivarium. This presentation will address some...
There is a growing debate about the usefulness of animal studies in biomedical research and drug development. Some of the challenges in translation from animals to human patients may be from...
Nonterminal blood collection from mice is frequently performed in biomedical research. Multiple phlebotomy sites and restraint techniques are available to investigators. Methods that minimize...
The aerodigestive tract is a combination of the respiratory tract and the upper portion of the digestive tract. As these two organ systems share many of the necessary structures used for swal...
Introduction:The cannulation of the cisterna magna in the rat is a valuable model for in-vivo sampling of cerebrospinal fluid for studying delivery of new drugs into the central nervous sys...
Compassion Fatigue can affect all those that care for and work with laboratory animals, including husbandry staff, veterinary staff, researchers, and other support staff. It is known as the &...
The ability to rapidly and accurately identify pain in mice is critical for providing them optimal care and welfare. To meet this need, we developed and validated the Grooming Transfer Test (...
This session will explore the interpretation of multi-species scattergrams in normal and pathologic conditions. Numerous case studies will be reviewed....
Tuberculosis (TB) is the No.1 cause of death due to a single infectious agent in the world today. According to the global report from World Health Organization, one third of world population...
Conspecific aggression is a common problem amongst laboratory housed male mice. While C57BL/6 are not the most aggressive strain we house, they are exceedingly common, and dealing with...
Welfare First, a programme developed to recognise the importance of welfare within the life sciences sector and to meet the aims of its position statement. Animal welfare is a priority,...
There is a considerable interest and need for evidence-based recommendations regarding the social housing of laboratory rabbits. This presentation will review the principles surrounding the s...
DATE: January 25, 2018TIME: 8:00AM PST, 10:00AM CSTProstate cancer (PCa) is the most common noncutaneous malignancy in men in the US. A significant fraction of advanced PCa treate...
DATE: November 15, 2017TIME: 09:00am PST, 12:00pm ESTMicroRNAs (miRNA) are a class of small non-coding RNAs (approximately 21 nt long) that bind complementary sequences in target mRNAs...
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